 Caenorhabditis elegans
"Caenorhabditis elegans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A species of nematode that is widely used in biological, biochemical, and genetic studies.
| Descriptor ID |
D017173
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| MeSH Number(s) |
B01.050.500.500.294.700.700.660.250.250
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| Concept/Terms |
Caenorhabditis elegans- Caenorhabditis elegans
- Caenorhabditis elegan
- elegan, Caenorhabditis
- elegans, Caenorhabditis
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Below are MeSH descriptors whose meaning is more general than "Caenorhabditis elegans".
Below are MeSH descriptors whose meaning is more specific than "Caenorhabditis elegans".
This graph shows the total number of publications written about "Caenorhabditis elegans" by people in UAMS Profiles by year, and whether "Caenorhabditis elegans" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 3 | 1 | 4 | | 2023 | 0 | 1 | 1 | | 2022 | 1 | 3 | 4 | | 2021 | 0 | 2 | 2 | | 2020 | 1 | 1 | 2 | | 2019 | 2 | 0 | 2 | | 2018 | 2 | 1 | 3 | | 2017 | 0 | 1 | 1 | | 2016 | 4 | 2 | 6 | | 2014 | 3 | 2 | 5 | | 2013 | 2 | 1 | 3 | | 2012 | 1 | 2 | 3 | | 2011 | 3 | 0 | 3 | | 2010 | 0 | 1 | 1 | | 2009 | 4 | 1 | 5 | | 2008 | 3 | 0 | 3 | | 2007 | 1 | 1 | 2 | | 2006 | 1 | 1 | 2 | | 2005 | 3 | 0 | 3 | | 2004 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2000 | 1 | 2 | 3 | | 1997 | 1 | 1 | 2 | | 1996 | 1 | 0 | 1 | | 1995 | 1 | 0 | 1 | | 1994 | 1 | 0 | 1 | | 1993 | 1 | 0 | 1 |
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Below are the most recent publications written about "Caenorhabditis elegans" by people in Profiles over the past ten years.
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Duckett M, Taylor MN, Bowman C, Vega NM. Parallel evolution of alternate morphotypes of Chryseobacterium gleum during experimental evolution with Caenorhabditis elegans. FEMS Microbiol Ecol. 2024 Apr 10; 100(5).
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Martinez MAQ, Zhao CZ, Moore FEQ, Yee C, Zhang W, Shen K, Martin BL, Matus DQ. Cell cycle perturbation uncouples mitotic progression and invasive behavior in a post-mitotic cell. Differentiation. 2024 May-Jun; 137:100765.
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Mazur A, Ayyadevara S, Mainali N, Patchett S, Uden M, Roa RI, Fahy GM, Shmookler Reis RJ. Model biological systems demonstrate the inducibility of pathways that strongly reduce cryoprotectant toxicity. Cryobiology. 2024 Jun; 115:104881.
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Balasubramaniam M, Narasimhappagari J, Liu L, Ganne A, Ayyadevara S, Atluri R, Ayyadevara H, Caldwell G, Shmookler Reis RJ, Barger SW, Griffin WST. Rescue of ApoE4-related lysosomal autophagic failure in Alzheimer's disease by targeted small molecules. Commun Biol. 2024 01 08; 7(1):60.
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AlAbdi L, Desbois M, Rusnac DV, Sulaiman RA, Rosenfeld JA, Lalani S, Murdock DR, Burrage LC, Billie Au PY, Towner S, Wilson WG, Wong L, Brunet T, Strobl-Wildemann G, Burton JE, Hoganson G, McWalter K, Begtrup A, Zarate YA, Christensen EL, Opperman KJ, Giles AC, Helaby R, Kania A, Zheng N, Grill B, Alkuraya FS. Loss-of-function variants in MYCBP2 cause neurobehavioural phenotypes and corpus callosum defects. Brain. 2023 04 19; 146(4):1373-1387.
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Ganne A, Balasubramaniam M, Mainali N, Atluri P, Shmookler Reis RJ, Ayyadevara S. Physiological Consequences of Targeting 14-3-3 and Its Interacting Partners in Neurodegenerative Diseases. Int J Mol Sci. 2022 Dec 07; 23(24).
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Sun Q, Vega NM, Cervantes B, Mancuso CP, Mao N, Taylor MN, Collins JJ, Khalil AS, Gore J, Lu TK. Enhancing nutritional niche and host defenses by modifying the gut microbiome. Mol Syst Biol. 2022 11; 18(11):e9933.
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Taylor MN, Spandana Boddu S, Vega NM. Using Single-Worm Data to Quantify Heterogeneity in Caenorhabditis elegans-Bacterial Interactions. J Vis Exp. 2022 07 22; (185).
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Turcu AL, Companys-Alemany J, Phillips MB, Patel DS, Gri??n-Ferr? C, Loza MI, Brea JM, P?rez B, Soto D, Sureda FX, Kurnikova MG, Johnson JW, Pall?s M, V?zquez S. Design, synthesis, and in?vitro and in?vivo characterization of new memantine analogs for Alzheimer's disease. Eur J Med Chem. 2022 Jun 05; 236:114354.
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Nedosekin DA, Chen T, Ayyadevara S, Zharov VP, Shmookler Reis RJ. Label-free photothermal disruption of cytotoxic aggregates rescues pathology in a C. elegans model of Huntington's disease. Sci Rep. 2021 10 05; 11(1):19732.
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Var?o AM, Silva JDS, Amaral LO, Aleixo LLP, Onduras A, Santos CS, Silva LPD, Ribeiro DE, Filho JLL, Bornhorst J, Stiboller M, Schwerdtle T, Alves LC, Soares FAA, Gubert P. Toxic effects of thallium acetate by acute exposure to the nematode C. elegans. J Trace Elem Med Biol. 2021 Dec; 68:126848.
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Wang W, Li J, Tan J, Wang M, Yang J, Zhang ZM, Li C, Basnakian AG, Tang HW, Perrimon N, Zhou Q. Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response. Nat Commun. 2021 01 20; 12(1):476.
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Rikitake M, Matsuda A, Murata D, Dejima K, Nomura KH, Abbott KL, Mitani S, Nomura K. Analysis of GPI-anchored proteins involved in germline stem cell proliferation in the Caenorhabditis elegans germline stem cell niche. J Biochem. 2020 Dec 26; 168(6):589-602.
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Adikes RC, Kohrman AQ, Martinez MAQ, Palmisano NJ, Smith JJ, Medwig-Kinney TN, Min M, Sallee MD, Ahmed OB, Kim N, Liu S, Morabito RD, Weeks N, Zhao Q, Zhang W, Feldman JL, Barkoulas M, Pani AM, Spencer SL, Martin BL, Matus DQ. Visualizing the metazoan proliferation-quiescence decision in vivo. Elife. 2020 12 22; 9.
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Tarkhov AE, Alla R, Ayyadevara S, Pyatnitskiy M, Menshikov LI, Shmookler Reis RJ, Fedichev PO. A universal transcriptomic signature of age reveals the temporal scaling of Caenorhabditis elegans aging trajectories. Sci Rep. 2019 05 14; 9(1):7368.
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Chen YZ, Kl?ditz K, Lee ES, Nguyen DP, Yuan Q, Johnson J, Lee-Yow Y, Hall A, Mitani S, Xia NS, Fadeel B, Xue D. Structure and function analysis of the C. elegans aminophospholipid translocase TAT-1. J Cell Sci. 2019 02 28; 132(5).
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Ayyadevara S, Ganne A, Hendrix RD, Balasubramaniam M, Shmookler Reis RJ, Barger SW. Functional assessments through novel proteomics approaches: Application to insulin/IGF signaling in neurodegenerative disease'. J Neurosci Methods. 2019 05 01; 319:40-46.
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Balasubramaniam M, Ayyadevara S, Shmookler Reis RJ. Structural insights into pro-aggregation effects of C. elegans CRAM-1 and its human ortholog SERF2. Sci Rep. 2018 10 05; 8(1):14891.
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Martin EM, Jackson MP, Gamerdinger M, Gense K, Karamonos TK, Humes JR, Deuerling E, Ashcroft AE, Radford SE. Conformational flexibility within the nascent polypeptide-associated complex enables its interactions with structurally diverse client proteins. J Biol Chem. 2018 06 01; 293(22):8554-8568.
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Ayyadevara S, Balasubramaniam M, Kakraba S, Alla R, Mehta JL, Shmookler Reis RJ. Aspirin-Mediated Acetylation Protects Against Multiple Neurodegenerative Pathologies by Impeding Protein Aggregation. Antioxid Redox Signal. 2017 Dec 10; 27(17):1383-1396.
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Ayyadevara S, Balasubramaniam M, Suri P, Mackintosh SG, Tackett AJ, Sullivan DH, Shmookler Reis RJ, Dennis RA. Proteins that accumulate with age in human skeletal-muscle aggregates contribute to declines in muscle mass and function in Caenorhabditis elegans. Aging (Albany NY). 2016 12 15; 8(12):3486-3497.
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Hao L, Ben-David O, Babb SM, Futerman AH, Cohen BM, Buttner EA. Clozapine Modulates Glucosylceramide, Clears Aggregated Proteins, and Enhances ATG8/LC3 in Caenorhabditis elegans. Neuropsychopharmacology. 2017 Mar; 42(4):951-962.
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Ayyadevara S, Balasubramaniam M, Johnson J, Alla R, Mackintosh SG, Shmookler Reis RJ. PIP3-binding proteins promote age-dependent protein aggregation and limit survival in C. elegans. Oncotarget. 2016 Aug 02; 7(31):48870-48886.
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Imanikia S, Galea F, Nagy E, Phillips DH, St?rzenbaum SR, Arlt VM. The application of the comet assay to assess the genotoxicity of environmental pollutants in the nematode Caenorhabditis elegans. Environ Toxicol Pharmacol. 2016 Jul; 45:356-61.
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Joo JH, Wang B, Frankel E, Ge L, Xu L, Iyengar R, Li-Harms X, Wright C, Shaw TI, Lindsten T, Green DR, Peng J, Hendershot LM, Kilic F, Sze JY, Audhya A, Kundu M. The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis. Mol Cell. 2016 05 19; 62(4):491-506.
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Wang X, Li N, Xiong N, You Q, Li J, Yu J, Qing H, Wang T, Cordell HJ, Isacson O, Vance JM, Martin ER, Zhao Y, Cohen BM, Buttner EA, Lin Z. Genetic Variants of Microtubule Actin Cross-linking Factor 1 (MACF1) Confer Risk for Parkinson's Disease. Mol Neurobiol. 2017 05; 54(4):2878-2888.
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Fu Q, Martin BL, Matus DQ, Gao L. Imaging multicellular specimens with real-time optimized tiling light-sheet selective plane illumination microscopy. Nat Commun. 2016 Mar 23; 7:11088.
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Ayyadevara S, Balasubramaniam M, Gao Y, Yu LR, Alla R, Shmookler Reis R. Proteins in aggregates functionally impact multiple neurodegenerative disease models by forming proteasome-blocking complexes. Aging Cell. 2015 Feb; 14(1):35-48.
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