 TNF-Related Apoptosis-Inducing Ligand
"TNF-Related Apoptosis-Inducing Ligand" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transmembrane-protein belonging to the TNF family of intercellular signaling proteins. It is a widely expressed ligand that activates APOPTOSIS by binding to TNF-RELATED APOPTOSIS-INDUCING LIGAND RECEPTORS. The membrane-bound form of the protein can be cleaved by specific CYSTEINE ENDOPEPTIDASES to form a soluble ligand form.
| Descriptor ID |
D053221
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| MeSH Number(s) |
D12.644.276.374.750.625 D12.644.276.972.625 D12.776.467.374.750.625 D12.776.467.972.625 D23.529.374.750.625 D23.529.972.625
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| Concept/Terms |
TNF-Related Apoptosis-Inducing Ligand- TNF-Related Apoptosis-Inducing Ligand
- Apoptosis-Inducing Ligand, TNF-Related
- TNF Related Apoptosis Inducing Ligand
- Tumor Necrosis Factor Ligand Superfamily Member 10
- TNF Superfamily, Member 10
- TRAIL Protein
- Apo-2 Ligand
- Apo 2 Ligand
- Apo-2L Protein
- Apo 2L Protein
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Below are MeSH descriptors whose meaning is more general than "TNF-Related Apoptosis-Inducing Ligand".
Below are MeSH descriptors whose meaning is more specific than "TNF-Related Apoptosis-Inducing Ligand".
This graph shows the total number of publications written about "TNF-Related Apoptosis-Inducing Ligand" by people in UAMS Profiles by year, and whether "TNF-Related Apoptosis-Inducing Ligand" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2010 | 3 | 0 | 3 | | 2009 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2004 | 0 | 4 | 4 | | 2002 | 0 | 1 | 1 |
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Below are the most recent publications written about "TNF-Related Apoptosis-Inducing Ligand" by people in Profiles over the past ten years.
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Ryu S, Ahn YJ, Yoon C, Chang JH, Park Y, Kim TH, Howland AR, Armstrong CA, Song PI, Moon AR. The regulation of combined treatment-induced cell death with recombinant TRAIL and bortezomib through TRAIL signaling in TRAIL-resistant cells. BMC Cancer. 2018 04 16; 18(1):432.
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Collison AM, Sokulsky LA, Sherrill JD, Nightingale S, Hatchwell L, Talley NJ, Walker MM, Rothenberg ME, Mattes J. TNF-related apoptosis-inducing ligand (TRAIL) regulates midline-1, thymic stromal lymphopoietin, inflammation, and remodeling in experimental eosinophilic esophagitis. J Allergy Clin Immunol. 2015 Oct; 136(4):971-82.
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