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Ping-Ching Hsu

TitleAssociate Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentEnvironmental Health Sciences, College of Public Health
DivisionEnvironmental Health Sciences
Address220 UAMS Campus Dr.
Mail Slot # 820
Little Rock AR 72205
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    Collapse Overview 

    Collapse Affiliation 
    Collapse member of
    Metabolomics Society
    American Association for Cancer Research (AACR)
    Metabolomics Association of North America (MANA)

    Collapse Teaching 

    Collapse Research 
    Collapse research overview
    My laboratory is interested in biomarker discovery using global metabolite profiling (metabolomics). We use metabolomics to identify the “metabotype” that are consisting of oxidized lipids and metabolites in patients and animal models hoping to find early indicators of chemotherapy-induced cardiotoxicity and cognitive impairments in breast cancer patients. We also work on addressing the issue of cigarette smoking especially menthol cigarette smoking that’s contributing to the disparity of lethal prostate cancer in African-Americans, by identifying smoking-related metabolomics patterns associated with highly aggressive prostate cancer in African-Americans compared to European-Americans.

    Collapse research activities and funding
    HT94252310924     (HSU, PING-CHING)Sep 1, 2023 - Aug 31, 2026
    US Department of Defense - Pass Through: University of Texas Southwestern Medical Center
    Modulation effect of folate on the association between inorganic arsenic and aggressive prostate cancer
    Role: Principal Investigator
    W81XWH-21-1-0226     (Ping-Ching Hsu)Apr 1, 2021 - Mar 31, 2024
    US Department of Defense
    Metabolomics of Menthol Cigarette Smoking and Risk for Aggressive Prostate Cancer Among African American Men
    Role: Principal Investigator
    W81XWH2110226     (LANDES, REID D)Apr 1, 2021 - Mar 31, 2024
    US Department of Defense
    Metabolomics of menthol cigarette smoking and risk for aggressive prostate cancer among African-American men
    Role: Principal Investigator
         (Hsu/Makhoul/Allen)Apr 1, 2021 - Mar 31, 2022
    Winthrop P. Rockefeller Team Science Pilot Award
    Feasibility study to improve the assessment of cancer treatment-related cognitive impairment.
    Role: Principal Investigator
    U01DD001285     (NEMBHARD, WENDY N)Dec 1, 2018 - Aug 31, 2023
    NIH
    RFA-DD-18-001 Birth Defects Study To Evaluate Pregnancy exposures (BD-STEPS) II Core & Component B Steps -Stillbirth
    Role: Co-Investigator
    R15CA231510     (HSU, PING-CHING)Sep 6, 2018 - May 31, 2022
    NIH/Nat. Cancer Institute
    Evaluating Impact of Diet and Fresh Food Access on Aggressive Prostate Cancer using Multi-Level Modeling
    Role: Principal Investigator
    1U01DD001229-01     Sep 1, 2018 - Aug 7, 2023
    Center for Disease Control and Prevention
    Component A: Arkansas Proposal to participate in the Birth Defect Study to Evaluate Pregnancy exposureS (BD-STEPS II)
    Role: Co-Investigator
    CI-Tobacco Prevention Internal Award     (ORLOFF, MOHAMMED S)Jul 1, 2017 - Jun 30, 2019
    UAMS Internal Research Awards
    Interaction of lug microbiome and tobaccorelated insults in lung cancer
    Role: Principal Investigator
    CI-TobaccoPreventionInternalAward     (ORLOFF, MOHAMMED S)Jul 1, 2017 - Jun 30, 2019
    UAMS Internal Research Awards
    Interaction of lug microbiome and tobaccorelated insults in lung cancer
    Role: Principal Investigator
    CPPS Pilot Award 2017     (QUICK, CHARLES M)Jul 1, 2017 - Dec 31, 2018
    UAMS College of Medicine
    Cancer Prevention and Population Sciences Program
    Role: Principal Investigator
    CPPSPilotAward2017     (QUICK, CHARLES M)Jul 1, 2017 - Dec 31, 2018
    UAMS College of Medicine
    Cancer Prevention and Population Sciences Program
    Role: Principal Investigator
    P20GM109005     (BOERMA, MARJAN)Jun 24, 2015 - May 31, 2025
    NIH
    Center for Studies of Host Response to Cancer Therapy
    Role Description: The goal of the study is to examine whether type of cigarette smoked contribute to racial disparity in prostate cancer.
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Wu CE, Chang CF, Huang CY, Yang CT, Kuo CS, Hsu PC, Chang JW. Feasibility and effectiveness of afatinib for poor performance status patients with EGFR-mutation-positive non-small-cell lung cancer: a retrospective cohort study. BMC Cancer. 2021 Jul 27; 21(1):859. PMID: 34315431.
      View in: PubMed
    2. Chu CH, Chiu TH, Wang CC, Chang WC, Huang AC, Liu CY, Wang CL, Ko HW, Chung FT, Hsu PC, Guo YK, Kuo CS, Yang CT. Consolidation treatment of durvalumab after chemoradiation in real-world patients with stage III unresectable non-small cell lung cancer. Thorac Cancer. 2020 06; 11(6):1541-1549. PMID: 32281272.
      View in: PubMed
    3. Huang SH, Huang AC, Wang CC, Chang WC, Liu CY, Pavlidis S, Ko HW, Chung FT, Hsu PC, Guo YK, Kuo CS, Yang CT. Front-line treatment of ceritinib improves efficacy over crizotinib for Asian patients with anaplastic lymphoma kinase fusion NSCLC: The role of systemic progression control. Thorac Cancer. 2019 12; 10(12):2274-2281. PMID: 31613427.
      View in: PubMed
    4. Hsu PC, Chang JW, Wang CC, Wu CT, Lin YC, Wang CL, Lin TY, Li SH, Wu YC, Kuo SC, Yang CT, Liu CY, Chen CH. Oral vinorelbine plus cisplatin with concomitant radiotherapy as induction therapy for stage III non-small cell lung cancer: Results of a single-arm prospective cohort study. Thorac Cancer. 2019 08; 10(8):1683-1691. PMID: 31276309.
      View in: PubMed
    5. Kuo SH, Wu MS, Yeh KH, Lin CW, Hsu PN, Chen LT, Cheng AL. Novel Insights of Lymphomagenesis of Helicobacter pylori-Dependent Gastric Mucosa-Associated Lymphoid Tissue Lymphoma. Cancers (Basel). 2019 Apr 17; 11(4). PMID: 30999581.
      View in: PubMed
    6. Hsu PC, Lan RS, Brasky TM, Marian C, Cheema AK, Ressom HW, Loffredo CA, Pickworth WB, Shields PG. Menthol Smokers: Metabolomic Profiling and Smoking Behavior. Cancer Epidemiol Biomarkers Prev. 2017 01; 26(1):51-60. PMID: 27628308.
      View in: PubMed
    7. Hsu PC, Lan RS, Brasky TM, Marian C, Cheema AK, Ressom HW, Loffredo CA, Pickworth WB, Shields PG. Metabolomic profiles of current cigarette smokers. Mol Carcinog. 2017 02; 56(2):594-606. PMID: 27341184.
      View in: PubMed
    8. Weng DY, Chen J, Taslim C, Hsu PC, Marian C, David SP, Loffredo CA, Shields PG. Persistent alterations of gene expression profiling of human peripheral blood mononuclear cells from smokers. Mol Carcinog. 2016 10; 55(10):1424-37. PMID: 26294040.
      View in: PubMed
    9. Hsu PI, Wu DC, Chen WC, Tseng HH, Yu HC, Wang HM, Kao SS, Lai KH, Chen A, Tsay FW. Randomized controlled trial comparing 7-day triple, 10-day sequential, and 7-day concomitant therapies for Helicobacter pylori infection. Antimicrob Agents Chemother. 2014 Oct; 58(10):5936-42. PMID: 25070099.
      View in: PubMed
    10. Tzeng HT, Tsai HF, Chyuan IT, Liao HJ, Chen CJ, Chen PJ, Hsu PN. Tumor necrosis factor-alpha induced by hepatitis B virus core mediating the immune response for hepatitis B viral clearance in mice model. PLoS One. 2014; 9(7):e103008. PMID: 25047809.
      View in: PubMed
    11. Chen WC, Chen YH, Hsu PI, Tsay FW, Chan HH, Cheng JS, Lai KH. Gastrointestinal hemorrhage in warfarin anticoagulated patients: incidence, risk factor, management, and outcome. Biomed Res Int. 2014; 2014:463767. PMID: 24987683.
      View in: PubMed
    12. Tsai WL, Lai KH, Liang HL, Hsu PI, Chan HH, Chen WC, Yu HC, Tsay FW, Wang HM, Tsai HC, Cheng JS. Hepatic arterial infusion chemotherapy for patients with huge unresectable hepatocellular carcinoma. PLoS One. 2014; 9(5):e92784. PMID: 24824520.
      View in: PubMed
    13. Chu TH, Chan HH, Kuo HM, Liu LF, Hu TH, Sun CK, Kung ML, Lin SW, Wang EM, Ma YL, Cheng KH, Lai KH, Wen ZH, Hsu PI, Tai MH. Celecoxib suppresses hepatoma stemness and progression by up-regulating PTEN. Oncotarget. 2014 Mar 30; 5(6):1475-90. PMID: 24721996.
      View in: PubMed
    14. Huang YW, Hsu CK, Lin SC, Wei SC, Hu JT, Chang HY, Liang CW, Chen DS, Chen PJ, Hsu PN, Yang SS, Kao JH. Reduced toll-like receptor 9 expression on peripheral CD14+ monocytes of chronic hepatitis B patients and its restoration by effective therapy. Antivir Ther. 2014; 19(7):637-43. PMID: 24622882.
      View in: PubMed
    15. Wang HM, Chan HH, Wu MJ, Hsu PI, Lin CK, Yu HC, Chen WC, Tsai WL, Tsay FW, Tsai TJ. Not only hysterectomy but also cesarean section can predict incomplete flexible sigmoidoscopy among patients with prior abdominal or pelvic surgery. J Chin Med Assoc. 2014 Mar; 77(3):122-7. PMID: 24388006.
      View in: PubMed
    16. Yu HC, Lin KH, Hsu PI, Tsay FW, Wang HM, Tsai TJ, Lai KH. Real-world application of the roadmap model in chronic hepatitis B patients with telbivudine therapy. Clin Ther. 2013 Sep; 35(9):1386-99. PMID: 24054706.
      View in: PubMed
    17. Tzeng HT, Hsu PN, Chen PJ. Immunocompetent nontransgenic mouse models for studying hepatitis B virus immune responses. J Gastroenterol Hepatol. 2013 Aug; 28 Suppl 1:116-9. PMID: 23855306.
      View in: PubMed
    18. Huang YW, Lin SC, Wei SC, Hu JT, Chang HY, Huang SH, Chen DS, Chen PJ, Hsu PN, Yang SS, Kao JH. Reduced Toll-like receptor 3 expression in chronic hepatitis B patients and its restoration by interferon therapy. Antivir Ther. 2013; 18(7):877-84. PMID: 23744559.
      View in: PubMed
    19. Hsu PC, Zhou B, Zhao Y, Ressom HW, Cheema AK, Pickworth W, Shields PG. Feasibility of identifying the tobacco-related global metabolome in blood by UPLC-QTOF-MS. J Proteome Res. 2013 Feb 01; 12(2):679-91. PMID: 23240883.
      View in: PubMed
    20. Tsai TJ, Lai KH, Lin CK, Chan HH, Wang EM, Tsai WL, Cheng JS, Yu HC, Chen WC, Hsu PI. The relationship between gallbladder status and recurrent biliary complications in patients with choledocholithiasis following endoscopic treatment. J Chin Med Assoc. 2012 Nov; 75(11):560-6. PMID: 23158033.
      View in: PubMed
    21. Kuo CH, Hsu PI, Kuo FC, Wang SS, Hu HM, Liu CJ, Chuah SK, Chen YH, Hsieh MC, Wu DC, Tseng HH. Comparison of 10 day bismuth quadruple therapy with high-dose metronidazole or levofloxacin for second-line Helicobacter pylori therapy: a randomized controlled trial. J Antimicrob Chemother. 2013 Jan; 68(1):222-8. PMID: 22984204.
      View in: PubMed
    22. Wang HM, Lo GH, Chen WC, Hsu PI, Yu HC, Lin CK, Chan HH, Tsai WL, Tsay FW, Liu TP, Wang EM, Lai KH. Efficacy of transient elastography in screening for large esophageal varices in patients with suspicious or proven liver cirrhosis. J Dig Dis. 2012 Aug; 13(8):430-8. PMID: 22788929.
      View in: PubMed
    23. Tzeng HT, Tsai HF, Liao HJ, Lin YJ, Chen L, Chen PJ, Hsu PN. PD-1 blockage reverses immune dysfunction and hepatitis B viral persistence in a mouse animal model. PLoS One. 2012; 7(6):e39179. PMID: 22761734.
      View in: PubMed
    24. Yen ML, Hsu PN, Liao HJ, Lee BH, Tsai HF. TRAF-6 dependent signaling pathway is essential for TNF-related apoptosis-inducing ligand (TRAIL) induces osteoclast differentiation. PLoS One. 2012; 7(6):e38048. PMID: 22719861.
      View in: PubMed
    25. Kao JT, Lai HC, Tsai SM, Lin PC, Chuang PH, Yu CJ, Cheng KS, Su WP, Hsu PN, Peng CY, Wu YY. Rather than interleukin-27, interleukin-6 expresses positive correlation with liver severity in na?ve hepatitis B infection patients. Liver Int. 2012 Jul; 32(6):928-36. PMID: 22230324.
      View in: PubMed
    26. Wu DC, Hsu PI, Tseng HH, Tsay FW, Lai KH, Kuo CH, Wang SW, Chen A. Helicobacter pylori infection: a randomized, controlled study comparing 2 rescue therapies after failure of standard triple therapies. Medicine (Baltimore). 2011 May; 90(3):180-185. PMID: 21512411.
      View in: PubMed
    27. Hu CY, Chang SK, Wu CS, Tsai WI, Hsu PN. Galectin-3 gene (LGALS3) +292C allele is a genetic predisposition factor for rheumatoid arthritis in Taiwan. Clin Rheumatol. 2011 Sep; 30(9):1227-33. PMID: 21475983.
      View in: PubMed
    28. Huang SC, Tsai HF, Tzeng HT, Liao HJ, Hsu PN. Lipid raft assembly and Lck recruitment in TRAIL costimulation mediates NF-?B activation and T cell proliferation. J Immunol. 2011 Jan 15; 186(2):931-9. PMID: 21160038.
      View in: PubMed
    29. Hsu PI, Lai KH, Liu CP. Esomeprazole with clopidogrel reduces peptic ulcer recurrence, compared with clopidogrel alone, in patients with atherosclerosis. Gastroenterology. 2011 Mar; 140(3):791-8. PMID: 21144850.
      View in: PubMed
    30. Hsu PN, Yang TC, Kao JT, Cheng KS, Lee YJ, Wang YM, Hsieh CT, Lin CW, Wu YY. Increased PD-1 and decreased CD28 expression in chronic hepatitis B patients with advanced hepatocellular carcinoma. Liver Int. 2010 Oct; 30(9):1379-86. PMID: 20738778.
      View in: PubMed
    31. Lin WC, Tsai HF, Kuo SH, Wu MS, Lin CW, Hsu PI, Cheng AL, Hsu PN. Translocation of Helicobacter pylori CagA into Human B lymphocytes, the origin of mucosa-associated lymphoid tissue lymphoma. Cancer Res. 2010 Jul 15; 70(14):5740-8. PMID: 20587516.
      View in: PubMed
    32. Lin YJ, Huang LR, Yang HC, Tzeng HT, Hsu PN, Wu HL, Chen PJ, Chen DS. Hepatitis B virus core antigen determines viral persistence in a C57BL/6 mouse model. Proc Natl Acad Sci U S A. 2010 May 18; 107(20):9340-5. PMID: 20439715.
      View in: PubMed
    33. Hsu PI, Chen CH, Hsiao M, Wu DC, Lin CY, Lai KH, Lu PJ. Diagnosis of gastric malignancy using gastric juice alpha1-antitrypsin. Cancer Epidemiol Biomarkers Prev. 2010 Feb; 19(2):405-11. PMID: 20086110.
      View in: PubMed
    34. Wang FW, Tu MS, Chuang HY, Yu HC, Cheng LC, Hsu PI. Erosive esophagitis in asymptomatic subjects: risk factors. Dig Dis Sci. 2010 May; 55(5):1320-4. PMID: 19685186.
      View in: PubMed
    35. Tsai TJ, Lai KH, Hsu PI, Tsai CC, Fu TY. Gallbladder cancer manifesting as recurrent common bile duct stone and duodenal ulcer bleeding. J Chin Med Assoc. 2009 Aug; 72(8):434-7. PMID: 19687000.
      View in: PubMed
    36. Chan HH, Lai KH, Lin CK, Tsai WL, Peng NJ, Hsu PI, Lo GH, Wei MC, Wang EM, Chang HW. Impact of food on hepatic clearance of patients after endoscopic sphincterotomy. J Chin Med Assoc. 2009 Jan; 72(1):10-4. PMID: 19181591.
      View in: PubMed
    37. Chen TA, Tsao YC, Chen A, Lo GH, Lin CK, Yu HC, Cheng LC, Hsu PI, Tsai WL. Effect of intravenous albumin on endotoxin removal, cytokines, and nitric oxide production in patients with cirrhosis and spontaneous bacterial peritonitis. Scand J Gastroenterol. 2009; 44(5):619-25. PMID: 19191184.
      View in: PubMed
    38. Peng NJ, Lai KH, Lo GH, Hsu PI. Comparison of noninvasive diagnostic tests for Helicobacter pylori infection. Med Princ Pract. 2009; 18(1):57-61. PMID: 19060493.
      View in: PubMed
    39. Chan HH, Lai KH, Lin CK, Tsai WL, Lo GH, Hsu PI, Wei MC, Wang EM. Effect of somatostatin in the prevention of pancreatic complications after endoscopic retrograde cholangiopancreatography. J Chin Med Assoc. 2008 Dec; 71(12):605-9. PMID: 19114324.
      View in: PubMed
    40. Pan MH, Hsieh MC, Hsu PC, Ho SY, Lai CS, Wu H, Sang S, Ho CT. 6-Shogaol suppressed lipopolysaccharide-induced up-expression of iNOS and COX-2 in murine macrophages. Mol Nutr Food Res. 2008 Dec; 52(12):1467-77. PMID: 18683823.
      View in: PubMed
    41. Wang HM, Lo GH, Hsu PI, Lin CK, Chan HH, Chen WC, Lai KH, Wang BW, Lin SL. Nodular regenerative hyperplasia of the liver. J Chin Med Assoc. 2008 Oct; 71(10):523-7. PMID: 18955187.
      View in: PubMed
    42. Lo GH, Chen WC, Lin CK, Tsai WL, Chan HH, Chen TA, Yu HC, Hsu PI, Lai KH. Improved survival in patients receiving medical therapy as compared with banding ligation for the prevention of esophageal variceal rebleeding. Hepatology. 2008 Aug; 48(2):580-7. PMID: 18666235.
      View in: PubMed
    43. Kuo SH, Yeh PY, Chen LT, Wu MS, Lin CW, Yeh KH, Tzeng YS, Chen JY, Hsu PN, Lin JT, Cheng AL. Overexpression of B cell-activating factor of TNF family (BAFF) is associated with Helicobacter pylori-independent growth of gastric diffuse large B-cell lymphoma with histologic evidence of MALT lymphoma. Blood. 2008 Oct 01; 112(7):2927-34. PMID: 18628489.
      View in: PubMed
    44. Yu HC, Lo GH, Lai KH, Hsu PI, Chen IS, Hsieh PP. Adenomyoma of the jejunum --- a rare cause of gastrointestinal bleeding. J Chin Med Assoc. 2008 Feb; 71(2):96-9. PMID: 18290255.
      View in: PubMed
    45. Wu CS, Hu CY, Hsu PN. Anti-SSB/La antibody is negatively associated with HLA-DR2 in chronic hepatitis C infection. Clin Rheumatol. 2008 Mar; 27(3):365-8. PMID: 17992468.
      View in: PubMed
    46. Chou MY, Hsu PI, Chou SL, Chou YM, Wang FW, Hsueh KC, Chen LK, Hwang SJ, Tu MS. Factors related to incomplete flexible sigmoidoscopy among adult Chinese in Taiwan. J Chin Med Assoc. 2007 Sep; 70(9):361-6. PMID: 17908649.
      View in: PubMed
    47. Chen TA, Lo GH, Lin CK, Lai KH, Wong HY, Yu HC, Hsu PI, Chen HH, Tsai WL, Chen WC. Acute pancreatitis-associated acute gastrointestinal mucosal lesions: incidence, characteristics, and clinical significance. J Clin Gastroenterol. 2007 Jul; 41(6):630-4. PMID: 17577121.
      View in: PubMed
    48. Wu YY, Tsai HF, Lin WC, Hsu PI, Shun CT, Wu MS, Hsu PN. Upregulation of CCL20 and recruitment of CCR6+ gastric infiltrating lymphocytes in Helicobacter pylori gastritis. Infect Immun. 2007 Sep; 75(9):4357-63. PMID: 17562763.
      View in: PubMed
    49. Hsu PC, Pan MH, Li LA, Chen CJ, Tsai SS, Guo YL. Exposure in utero to 2,2',3,3',4,6'-hexachlorobiphenyl (PCB 132) impairs sperm function and alters testicular apoptosis-related gene expression in rat offspring. Toxicol Appl Pharmacol. 2007 May 15; 221(1):68-75. PMID: 17445852.
      View in: PubMed
    50. Li KJ, Yu CL, Hsu CY, Hsieh SC, Hsu PN. Spinal pseudoarthrosis: a rare complication in psoriatic arthritis. J Formos Med Assoc. 2006 Aug; 105(8):685-8. PMID: 16935772.
      View in: PubMed
    51. Tseng LH, Lee CW, Pan MH, Tsai SS, Li MH, Chen JR, Lay JJ, Hsu PC. Postnatal exposure of the male mouse to 2,2',3,3',4,4',5,5',6,6'-decabrominated diphenyl ether: decreased epididymal sperm functions without alterations in DNA content and histology in testis. Toxicology. 2006 Jul 05; 224(1-2):33-43. PMID: 16713668.
      View in: PubMed
    52. Chen WC, Lo GH, Tsai WL, Hsu PI, Lin CK, Lai KH. Emergency endoscopic variceal ligation versus somatostatin for acute esophageal variceal bleeding. J Chin Med Assoc. 2006 Feb; 69(2):60-7. PMID: 16570572.
      View in: PubMed
    53. Lin TC, Chien SC, Hsu PC, Li LA. Mechanistic study of polychlorinated biphenyl 126-induced CYP11B1 and CYP11B2 up-regulation. Endocrinology. 2006 Mar; 147(3):1536-44. PMID: 16396990.
      View in: PubMed
    54. Hsu PI, Lai KH, Lin CK, Chen WC, Yu HC, Cheng JS, Tsay FW, Wu CJ, Lo CC, Tseng HH, Yamaoka Y, Chen JL, Lo GH. A prospective randomized trial of esomeprazole- versus pantoprazole-based triple therapy for Helicobacter pylori eradication. Am J Gastroenterol. 2005 Nov; 100(11):2387-92. PMID: 16279889.
      View in: PubMed
    55. Tsai WL, Lai KH, Lin CK, Chan HH, Lo CC, Hsu PI, Chen WC, Cheng JS, Lo GH. Composition of common bile duct stones in Chinese patients during and after endoscopic sphincterotomy. World J Gastroenterol. 2005 Jul 21; 11(27):4246-9. PMID: 16015699.
      View in: PubMed
    56. Hung CH, Li CY, Lai YS, Hsu PC, Hua YM, Yang KD. Discrepant clinical responses and blood chemokine profiles between two non-steroidal anti-inflammatory medications for children with mild persistent asthma. Pediatr Allergy Immunol. 2005 Jun; 16(4):306-9. PMID: 15943593.
      View in: PubMed
    57. Hsu PI, Jwo JJ, Tseng HH, Lai KH, Lo GH, Lo CC, Wu CJ, Chuah SK, Hwang IR, Chen JL, Chen YS, Chen A. Association of the myeloperoxidase -468G-->A polymorphism with gastric inflammation and duodenal ulcer risk. World J Gastroenterol. 2005 May 14; 11(18):2796-801. PMID: 15884126.
      View in: PubMed
    58. Lu H, Hsu PI, Graham DY, Yamaoka Y. Duodenal ulcer promoting gene of Helicobacter pylori. Gastroenterology. 2005 Apr; 128(4):833-48. PMID: 15825067.
      View in: PubMed
    59. Chou AH, Tsai HF, Wu YY, Hu CY, Hwang LH, Hsu PI, Hsu PN. Hepatitis C virus core protein modulates TRAIL-mediated apoptosis by enhancing Bid cleavage and activation of mitochondria apoptosis signaling pathway. J Immunol. 2005 Feb 15; 174(4):2160-6. PMID: 15699147.
      View in: PubMed
    60. Lin CP, Yu HC, Cheng JS, Lai KH, Lo GH, Hsu PI, Lin CK, Chen HH, Lo CC, Liang HL, Tseng HH. Clinical effects of intra-arterial infusion chemotherapy with cisplatin, mitomycin C, leucovorin and 5-flourouracil for unresectable advanced hepatocellular carcinoma. J Chin Med Assoc. 2004 Dec; 67(12):602-10. PMID: 15779483.
      View in: PubMed
    61. Lo GH, Chen WC, Chen MH, Tsai WL, Chan HH, Cheng LC, Hsu PI, Lai KH. The characteristics and the prognosis for patients presenting with actively bleeding esophageal varices at endoscopy. Gastrointest Endosc. 2004 Nov; 60(5):714-20. PMID: 15557947.
      View in: PubMed
    62. Chen WC, Lo GH, Lai KH, Cheng JS, Hsu PI, Lin CK. Development of hepatocellular carcinoma after successful management of esophageal variceal bleeding. J Chin Med Assoc. 2004 Nov; 67(11):557-64. PMID: 15720069.
      View in: PubMed
    63. Tsai CS, Hsu PC, Huang GS, Lin TC, Hong GJ, Shih CM, Li CY. Midazolam attenuates adenosine diphosphate-induced P-selectin expression and platelet-leucocyte aggregation. Eur J Anaesthesiol. 2004 Nov; 21(11):871-6. PMID: 15717703.
      View in: PubMed
    64. Hsu PC, Huang YT, Tsai ML, Wang YJ, Lin JK, Pan MH. Induction of apoptosis by shikonin through coordinative modulation of the Bcl-2 family, p27, and p53, release of cytochrome c, and sequential activation of caspases in human colorectal carcinoma cells. J Agric Food Chem. 2004 Oct 06; 52(20):6330-7. PMID: 15453709.
      View in: PubMed
    65. Huang GS, Li CY, Hsu PC, Tsai CS, Lin TC, Wong CS. Sevoflurane anesthesia attenuates adenosine diphosphate-induced P-selectin expression and platelet-leukocyte conjugate formation. Anesth Analg. 2004 Oct; 99(4):1121-1126. PMID: 15385361.
      View in: PubMed
    66. Wu YY, Tsai HF, Lin WC, Chou AH, Chen HT, Yang JC, Hsu PI, Hsu PN. Helicobacter pylori enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in human gastric epithelial cells. World J Gastroenterol. 2004 Aug 15; 10(16):2334-9. PMID: 15285015.
      View in: PubMed
    67. Wu CJ, Hsu PI, Lo GH, Lo CC, Lin CK, Shie CB, Peng NJ, Tseng HH, Jou HS, Tsai PM, Chen A, Chen JL, Lai KH. Comparison of cetraxate-based and pantoprazole-based triple therapies in the treatment of Helicobacter pylori infection. J Chin Med Assoc. 2004 Apr; 67(4):161-7. PMID: 15244013.
      View in: PubMed
    68. Lo GH, Chen WC, Chen MH, Lin CP, Lo CC, Hsu PI, Cheng JS, Lai KH. Endoscopic ligation vs. nadolol in the prevention of first variceal bleeding in patients with cirrhosis. Gastrointest Endosc. 2004 Mar; 59(3):333-8. PMID: 14997127.
      View in: PubMed
    69. Tsai HF, Lai JJ, Chou AH, Wang TF, Wu CS, Hsu PN. Induction of costimulation of human CD4 T cells by tumor necrosis factor-related apoptosis-inducing ligand: possible role in T cell activation in systemic lupus erythematosus. Arthritis Rheum. 2004 Feb; 50(2):629-39. PMID: 14872508.
      View in: PubMed
    70. Chen MY, Lee KL, Hsu PN, Wu CS, Wu CH. Is there an ethnic difference in the prevalence of lupus cystitis? A report of six cases. Lupus. 2004; 13(4):263-9. PMID: 15176663.
      View in: PubMed
    71. Li CY, Tsai CS, Hsu PC, Chueh SH, Wong CS, Ho ST. Lidocaine attenuates monocyte chemoattractant protein-1 production and chemotaxis in human monocytes: possible mechanisms for its effect on inflammation. Anesth Analg. 2003 Nov; 97(5):1312-1316. PMID: 14570645.
      View in: PubMed
    72. Wang YY, Lo GH, Lai KH, Cheng JS, Lin CK, Hsu PI. Increased serum concentrations of tumor necrosis factor-alpha are associated with disease progression and malnutrition in hepatocellular carcinoma. J Chin Med Assoc. 2003 Oct; 66(10):593-8. PMID: 14703276.
      View in: PubMed
    73. Yeh CL, Lai KH, Lo GH, Lin CK, Hsu PI, Chan HH, Tsai WL, Lin CP. Endoscopic treatment in a patient with obstructive jaundice caused by pancreatic pseudocyst. J Chin Med Assoc. 2003 Sep; 66(9):555-9. PMID: 14649681.
      View in: PubMed
    74. Li CY, Tsai CS, Hsu PC, Wu CT, Wong CS, Ho ST. Dobutamine modulates lipopolysaccharide-induced macrophage inflammatory protein-1alpha and interleukin-8 production in human monocytes. Anesth Analg. 2003 Jul; 97(1):210-5, table of contents. PMID: 12818968.
      View in: PubMed
    75. Li CY, Tsai CS, Chueh SH, Hsu PC, Wang JY, Wong CS, Ho ST. Dobutamine inhibits monocyte chemoattractant protein-1 production and chemotaxis in human monocytes. Anesth Analg. 2003 Jul; 97(1):205-9, table of contents. PMID: 12818967.
      View in: PubMed
    76. Hsu PC, Li MH, Guo YL. Postnatal exposure of 2,2',3,3',4,6'-hexachlorobiphenyl and 2,2',3,4',5',6-hexachlorobiphenyl on sperm function and hormone levels in adult rats. Toxicology. 2003 May 03; 187(2-3):117-26. PMID: 12699901.
      View in: PubMed
    77. Yeh GC, Chen JC, Tsai HC, Wu HH, Lin CY, Hsu PC, Peng YC. Amphetamine inhibits the N-methyl-D-aspartate receptor-mediated responses by directly interacting with the receptor/channel complex. J Pharmacol Exp Ther. 2002 Mar; 300(3):1008-16. PMID: 11861810.
      View in: PubMed
    78. Chen JY, Hsu PC, Hsu IL, Yeh GC. Sequential up-regulation of the c-fos, c-jun and bax genes in the cortex, striatum and cerebellum induced by a single injection of a low dose of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in C57BL/6 mice. Neurosci Lett. 2001 Nov 13; 314(1-2):49-52. PMID: 11698144.
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