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Cytochrome P-450 CYP1A2

"Cytochrome P-450 CYP1A2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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A cytochrome P-450 monooxygenase that can be induced by polycyclic aromatic xenobiotics in the liver of human and several animal species. This enzyme is of significant clinical interest due to the large number of drug interactions associated with its induction and its metabolism of THEOPHYLLINE. Caffeine is considered to be a model substrate for this enzyme. CYP1A2 activity can also be increased by environmental factors such as cigarette smoking, charbroiled meat, cruciferous vegetables, and a number of drugs including phenytoin, phenobarbital, and omeprazole.


expand / collapse publications
This graph shows the total number of publications written about "Cytochrome P-450 CYP1A2" by people in UAMS Profiles by year, and whether "Cytochrome P-450 CYP1A2" was a major or minor topic of these publications.
Bar chart showing 29 publications over 14 distinct years, with a maximum of 4 publications in 2008
To see the data from this visualization as text, click here.