 Steroid 21-Hydroxylase
"Steroid 21-Hydroxylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An adrenal microsomal cytochrome P450 enzyme that catalyzes the 21-hydroxylation of steroids in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP21 gene, converts progesterones to precursors of adrenal steroid hormones (CORTICOSTERONE; HYDROCORTISONE). Defects in CYP21 cause congenital adrenal hyperplasia (ADRENAL HYPERPLASIA, CONGENITAL).
| Descriptor ID |
D013255
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| MeSH Number(s) |
D08.244.453.915.760 D08.811.682.690.708.170.915.760 D08.811.682.690.708.783.760 D12.776.422.220.453.915.760
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| Concept/Terms |
Steroid 21-Hydroxylase- Steroid 21-Hydroxylase
- Steroid 21 Hydroxylase
- Cytochrome P-450 21-Hydroxylase
- Cytochrome P 450 21 Hydroxylase
- Cytochrome P-450 c21
- Cytochrome P 450 c21
- P-450 c21, Cytochrome
- Steroid-21-Hydroxylase
- Cytochrome P-450(c-21)
- Cytochrome P450c21
- Progesterone 21-Hydroxylase
- Progesterone 21 Hydroxylase
- Steroid 21-Monooxygenase
- Steroid 21 Monooxygenase
- 21-Hydroxylase
- 21 Hydroxylase
- Cytochrome P-450 CYP21
- Cytochrome P 450 CYP21
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Below are MeSH descriptors whose meaning is more general than "Steroid 21-Hydroxylase".
Below are MeSH descriptors whose meaning is more specific than "Steroid 21-Hydroxylase".
This graph shows the total number of publications written about "Steroid 21-Hydroxylase" by people in UAMS Profiles by year, and whether "Steroid 21-Hydroxylase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Steroid 21-Hydroxylase" by people in Profiles over the past ten years.
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Raisingani M, Contreras MF, Prasad K, Pappas JG, Kluge ML, Shah B, David R. Unusual phenotype of congenital adrenal hyperplasia (CAH) with a novel mutation of the CYP21A2 gene. J Pediatr Endocrinol Metab. 2016 Jul 01; 29(7):867-71.
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Krone N, Rose IT, Willis DS, Hodson J, Wild SH, Doherty EJ, Hahner S, Parajes S, Stimson RH, Han TS, Carroll PV, Conway GS, Walker BR, MacDonald F, Ross RJ, Arlt W. Genotype-phenotype correlation in 153 adult patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency: analysis of the United Kingdom Congenital adrenal Hyperplasia Adult Study Executive (CaHASE) cohort. J Clin Endocrinol Metab. 2013 Feb; 98(2):E346-54.
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