 Antihypertensive Agents
"Antihypertensive Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
| Descriptor ID |
D000959
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| MeSH Number(s) |
D27.505.954.411.162
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| Concept/Terms |
Antihypertensive Agents- Antihypertensive Agents
- Agents, Antihypertensive
- Antihypertensives
- Anti-Hypertensives
- Anti Hypertensives
- Antihypertensive Drugs
- Drugs, Antihypertensive
- Anti-Hypertensive Agents
- Agents, Anti-Hypertensive
- Anti Hypertensive Agents
- Anti-Hypertensive Drugs
- Anti Hypertensive Drugs
- Drugs, Anti-Hypertensive
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Below are MeSH descriptors whose meaning is more general than "Antihypertensive Agents".
Below are MeSH descriptors whose meaning is more specific than "Antihypertensive Agents".
This graph shows the total number of publications written about "Antihypertensive Agents" by people in UAMS Profiles by year, and whether "Antihypertensive Agents" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2024 | 4 | 0 | 4 | | 2023 | 0 | 2 | 2 | | 2022 | 2 | 1 | 3 | | 2021 | 2 | 0 | 2 | | 2020 | 4 | 4 | 8 | | 2019 | 1 | 1 | 2 | | 2018 | 3 | 3 | 6 | | 2017 | 2 | 2 | 4 | | 2016 | 2 | 0 | 2 | | 2015 | 0 | 2 | 2 | | 2014 | 8 | 2 | 10 | | 2013 | 5 | 3 | 8 | | 2012 | 7 | 1 | 8 | | 2011 | 3 | 2 | 5 | | 2010 | 3 | 2 | 5 | | 2009 | 3 | 1 | 4 | | 2008 | 1 | 3 | 4 | | 2007 | 0 | 2 | 2 | | 2006 | 2 | 2 | 4 | | 2004 | 1 | 3 | 4 | | 2003 | 2 | 0 | 2 | | 2002 | 3 | 1 | 4 | | 1999 | 1 | 0 | 1 | | 1997 | 2 | 0 | 2 | | 1996 | 3 | 1 | 4 |
To return to the timeline, click here.
Below are the most recent publications written about "Antihypertensive Agents" by people in Profiles over the past ten years.
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Moore MD, Kuo HC, Sinkey RG, Boggess K, Dugoff L, Sibai B, Lawrence K, Hughes BL, Bell J, Aagaard K, Edwards RK, Gibson KS, Haas DM, Plante L, Metz TD, Casey B, Esplin S, Longo S, Hoffman MK, Saade GR, Hoppe KK, Foroutan J, Tuuli M, Owens MY, Simhan HN, Frey HA, Rosen T, Palatnik A, Baker S, August P, Reddy UM, Kinzler W, Su EJ, Krishna I, Nguyen NA, Norton ME, Skupski D, El-Sayed YY, Ogunyemi D, Librizzi R, Pereira L, Magann EF, Habli M, Williams S, Mari G, Pridjian G, McKenna DS, Parrish M, Chang E, Osmundson S, Qui?ones JN, Leach J, Sanusi A, Galis ZS, Harper L, Ambalavanan N, Szychowski JM, Tita ATN. Mean Arterial Pressure and Neonatal Outcomes in Pregnancies Complicated by Mild Chronic Hypertension. Obstet Gynecol. 2024 Jul 01; 144(1):101-108.
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Sanusi AA, Leach J, Boggess K, Dugoff L, Sibai B, Lawrence K, Hughes BL, Bell J, Aagaard K, Edwards RK, Gibson KS, Haas DM, Plante L, Metz TD, Casey B, Esplin S, Longo S, Hoffman MK, Saade GR, Hoppe KK, Foroutan J, Tuuli M, Owens MY, Simhan HN, Frey H, Rosen T, Palatnik A, Baker S, August P, Reddy UM, Su EJ, Krishna I, Nguyen NA, Norton ME, Skupski D, El-Sayed YY, Ogunyemi D, Galis ZS, Harper L, Ambalavanan N, Geller NL, Kuo HC, Sinkey RG, Librizzi R, Pereira L, Magann EF, Habli M, Williams S, Mari G, Pridjian G, McKenna DS, Parrish M, Chang E, Osmundson S, Quinones J, Szychowski JM, Tita ATN. Pregnancy Outcomes of Nifedipine Compared With Labetalol for Oral Treatment of Mild Chronic Hypertension. Obstet Gynecol. 2024 Jul 01; 144(1):126-134.
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Smith KM, Keshwani S, Walsh MG, Winterstein AG, Gurka MJ, Libby A, Hogan WR, Pepine CJ, Cooper-DeHoff RM, Smith SM. Initial Antihypertensive Prescribing in Relation to Blood Pressure Among Florida Medicaid and Medicare Recipients in the OneFlorida+ Research Consortium. Hypertension. 2024 Feb; 81(2):e7-e9.
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Jafari E, Cooper-DeHoff RM, Effron MB, Hogan WR, McDonough CW. Characteristics and Predictors of Apparent Treatment-Resistant Hypertension in Real-World Populations Using Electronic Health Record-Based Data. Am J Hypertens. 2024 01 01; 37(1):60-68.
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Weinreb RN, Christie WC, Medeiros FA, Craven ER, Kim K, Nguyen A, Bejanian M, Wirta DL. Single Administration of Bimatoprost Implant: Effects on 24-Hour Intraocular Pressure and 1-Year?Outcomes. Ophthalmol Glaucoma. 2023 Nov-Dec; 6(6):599-608.
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Imig JD. Bioactive lipids in hypertension. Adv Pharmacol. 2023; 97:1-35.
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Charisis S, Rashid T, Liu H, Ware JB, Jensen PN, Austin TR, Li K, Fadaee E, Hilal S, Chen C, Hughes TM, Romero JR, Toledo JB, Longstreth WT, Hohman TJ, Nasrallah I, Bryan RN, Launer LJ, Davatzikos C, Seshadri S, Heckbert SR, Habes M. Assessment of Risk Factors and Clinical Importance of Enlarged Perivascular Spaces by Whole-Brain Investigation in the Multi-Ethnic Study of Atherosclerosis. JAMA Netw Open. 2023 04 03; 6(4):e239196.
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Smith SM, Winterstein AG, Gurka MJ, Walsh MG, Keshwani S, Libby AM, Hogan WR, Pepine CJ, Cooper-DeHoff RM. Initial Antihypertensive Regimens in Newly Treated Patients: Real World Evidence From the OneFlorida+ Clinical Research Network. J Am Heart Assoc. 2023 01 03; 12(1):e026652.
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Weinreb RN, Bacharach J, Brubaker JW, Medeiros FA, Bejanian M, Bernstein P, Robinson MR. Bimatoprost Implant Biodegradation in the Phase 3, Randomized, 20-Month ARTEMIS Studies. J Ocul Pharmacol Ther. 2023 Jan-Feb; 39(1):55-62.
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Salah HM, Mehta JL. Best time for administration of antihypertensive medications: morning or evening? Lancet. 2022 10 22; 400(10361):1383-1385.
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Rogers SC, Ko YA, Quyyumi AA, Hajjar I. Differential Sex-Specific Effects of Angiotensin-Converting Enzyme Inhibition and Angiotensin Receptor Blocker Therapy on Arterial Function in Hypertension: CALIBREX Trial. Hypertension. 2022 10; 79(10):2316-2327.
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Scelfo C, ElSheikh RH, Shamim MM, Abbasian J, Ghaffarieh A, Elhusseiny AM. Ocular Surface Disease in Glaucoma Patients. Curr Eye Res. 2023 03; 48(3):219-230.
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Dalli LL, Andrew NE, Kim J, Cadilhac DA, Sanfilippo FM, Thrift AG, Nelson MR, Lannin NA, Olaiya MT, Ryan OF, Booth B, Gall S, Kilkenny MF. Understanding of medications and associations with adherence, unmet needs, and perceived control of risk factors at two years post-stroke. Res Social Adm Pharm. 2022 09; 18(9):3542-3549.
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Adeneye AA, Olorundare OE, Omobowale TO, Akinsola AO, Kolo PM, Albrecht RMA, Crooks PA. Selected Antihypertensive Agents and Their Fixed-Dose Combinations Effectively Ameliorate Trastuzumab-Mediated Cardiac Dysfunction In Rats. Niger J Physiol Sci. 2021 Jun 30; 36(1):57-65.
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Mohandas R, Chamarthi G, Bozorgmehri S, Carlson J, Ozrazgat-Baslanti T, Ruchi R, Shukla A, Kazory A, Bihorac A, Canales M, Segal MS. Pro Re Nata Antihypertensive Medications and Adverse Outcomes in Hospitalized Patients: A Propensity-Matched Cohort Study. Hypertension. 2021 08; 78(2):516-524.
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Mathur P, Kadavath S, Marsh JD, Mehta JL. Chronotherapy for hypertension: improvement in patient outcomes with bedtime administration of antihypertensive drugs. Eur Heart J. 2020 12 21; 41(48):4577-4579.
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Henry D. Antihypertensive drugs and COVID-19. Heart. 2021 01; 107(1):85.
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Sharma T, Mathur P, Mehta JL. Daytime or Nighttime Administration of Antihypertensive Medications? Am J Hypertens. 2020 11 03; 33(11):987-989.
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Gawrys O, Huskov? Z, Baranowska I, Walkowska A, Sadowski J, Kikerlov? S, Vanourkov? Z, Honetschl?gerov? Z, ?karoupkov? P, Cervenka L, Falck JR, Imig JD, Kompanowska-Jezierska E. Combined treatment with epoxyeicosatrienoic acid analog and 20-hydroxyeicosatetraenoic acid antagonist provides substantial hypotensive effect in spontaneously hypertensive rats. J Hypertens. 2020 09; 38(9):1802-1810.
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Teeter BS, Thomas JL, Curran GM, Balamurugan A. Classifying intervention modifications in the community pharmacy context: A demonstration study. J Am Pharm Assoc (2003). 2020 Nov - Dec; 60(6):e230-e235.
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Critser PJ, Higano NS, Lang SM, Kingma PS, Fleck RJ, Hirsch R, Taylor MD, Woods JC. Cardiovascular magnetic resonance imaging derived septal curvature in neonates with bronchopulmonary dysplasia associated pulmonary hypertension. J Cardiovasc Magn Reson. 2020 07 23; 22(1):50.
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Magvanjav O, Cooper-Dehoff RM, McDonough CW, Gong Y, Hogan WR, Johnson JA. Combination Antihypertensive Therapy Prescribing and Blood Pressure Control in a Real-World Setting. Am J Hypertens. 2020 04 01; 33(4):316-324.
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Modrall JG, Zhu H, Weaver FA. Clinical predictors of blood pressure response after renal artery stenting. J Vasc Surg. 2020 10; 72(4):1269-1275.
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Amr BS, Lippmann M, Tobbia P, Isom N, Dalia T, Buechler T, Pierpoline M, Patel N, Hockstad E, Wiley M, Tadros P, Mehta A, Earnest M, Chen JG, Gupta K. Impact of short term oral steroid use for intravenous contrast media hypersensitivity prophylaxis in diabetic patients undergoing nonemergent coronary angiography or interventions. Catheter Cardiovasc Interv. 2020 12; 96(7):1392-1398.
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Raisingani M, Brar PC. Characterization of the duration of treatment with diazoxide in infants with prolonged hyperinsulinism (PHI). J Pediatr Endocrinol Metab. 2019 Nov 26; 32(11):1241-1245.
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Inger HE, McGregor ML, Jordan CO, Reem RE, Aylward SC, Scoville NM, Bai S, Rogers DL. Surgical intervention in pediatric intracranial hypertension: incidence, risk factors, and visual outcomes. J AAPOS. 2019 04; 23(2):96.e1-96.e7.
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Magvanjav O, Cooper-DeHoff RM, McDonough CW, Gong Y, Segal MS, Hogan WR, Johnson JA. Antihypertensive therapy prescribing patterns and correlates of blood pressure control among hypertensive patients with chronic kidney disease. J Clin Hypertens (Greenwich). 2019 01; 21(1):91-101.
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Sedl?kov? L, Kikerlov? S, Huskov? Z, Cervenkov? L, Ch?bov? VC, Zicha J, Falck JR, Imig JD, Kompanowska-Jezierska E, Sadowski J, Kr?tk? V, Cervenka L, Kopkan L. 20-Hydroxyeicosatetraenoic acid antagonist attenuates the development of malignant hypertension and reverses it once established: a study in Cyp1a1-Ren-2 transgenic rats. Biosci Rep. 2018 10 31; 38(5).
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Ahmed HA, Ishrat T, Pillai B, Fouda AY, Sayed MA, Eldahshan W, Waller JL, Ergul A, Fagan SC. RAS modulation prevents progressive cognitive impairment after experimental stroke: a randomized, blinded preclinical trial. J Neuroinflammation. 2018 Aug 13; 15(1):229.
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Correa A, Rochlani Y, Khan MH, Aronow WS. Pharmacological management of hypertension in the elderly and frail populations. Expert Rev Clin Pharmacol. 2018 Aug; 11(8):805-817.
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Cervenka L, Huskov? Z, Kopkan L, Kikerlov? S, Sedl?kov? L, Vanourkov? Z, Al?nov? P, Kol?r F, Hammock BD, Hwang SH, Imig JD, Falck JR, Sadowski J, Kompanowska-Jezierska E, Neck?r J. Two pharmacological epoxyeicosatrienoic acid-enhancing therapies are effectively antihypertensive and reduce the severity of ischemic arrhythmias in rats with angiotensin II-dependent hypertension. J Hypertens. 2018 06; 36(6):1326-1341.
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Pakravan M, Esfandiari H, Yazdani S, Doozandeh A, Dastborhan Z, Gerami E, Kheiri B, Pakravan P, Yaseri M, Hassanpour K. Clinical outcomes of Ahmed glaucoma valve implantation in pediatric glaucoma. Eur J Ophthalmol. 2019 Jan; 29(1):44-51.
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Torok RD, Li JS, Kannankeril PJ, Atz AM, Bishai R, Bolotin E, Breitenstein S, Chen C, Diacovo T, Feltes T, Furlong P, Hanna M, Graham EM, Hsu D, Ivy DD, Murphy D, Kammerman LA, Kearns G, Lawrence J, Lebeaut B, Li D, Male C, McCrindle B, Mugnier P, Newburger JW, Pearson GD, Peiris V, Percival L, Pina M, Portman R, Shaddy R, Stockbridge NL, Temple R, Hill KD. Recommendations to Enhance Pediatric Cardiovascular Drug Development: Report of a Multi-Stakeholder Think Tank. J Am Heart Assoc. 2018 02 10; 7(4).
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Rochlani Y, Khan MH, Aronow WS. Managing Hypertension in Patients Aged 75?Years and Older. Curr Hypertens Rep. 2017 Oct 18; 19(11):88.
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Ferdinand KC, Yadav K, Nasser SA, Clayton-Jeter HD, Lewin J, Cryer DR, Senatore FF. Disparities in hypertension and cardiovascular disease in blacks: The critical role of medication adherence. J Clin Hypertens (Greenwich). 2017 Oct; 19(10):1015-1024.
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Hogan WR, Hanna J, Hicks A, Amirova S, Bramblett B, Diller M, Enderez R, Modzelewski T, Vasconcelos M, Delcher C. Therapeutic indications and other use-case-driven updates in the drug ontology: anti-malarials, anti-hypertensives, opioid analgesics, and a large term request. J Biomed Semantics. 2017 Mar 03; 8(1):10.
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Rochlani Y, Khan MH, Banach M, Aronow WS. Are two drugs better than one? A review of combination therapies for hypertension. Expert Opin Pharmacother. 2017 Mar; 18(4):377-386.
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Theodoropoulou S, Ellabban AA, Johnston RL, Cilliers H, Mohamed Q, Sallam AB. Short-term safety of dexamethasone implant for treatment of macular edema due to retinal vein occlusion, in eyes with glaucoma or treated ocular hypertension. Graefes Arch Clin Exp Ophthalmol. 2017 Apr; 255(4):725-732.
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Bagherani N, Smoller BR. Efficacy of bimatoprost in the treatment of non-facial vitiligo. Dermatol Ther. 2017 Mar; 30(2).
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Khurshid K, Yabes J, Weiss PM, Dharia S, Brown L, Unruh M, Jhamb M. Effect of Antihypertensive Medications on the Severity of Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis. J Clin Sleep Med. 2016 08 15; 12(8):1143-51.
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Hye Khan MA, Sharma A, Rarick KR, Roman RJ, Harder DR, Imig JD. Elevated Aminopeptidase P Attenuates Cerebral Arterial Responses to Bradykinin in Fawn-Hooded Hypertensive Rats. PLoS One. 2015; 10(12):e0145335.
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Imig JD. Epoxyeicosatrienoic acids, hypertension, and kidney injury. Hypertension. 2015 Mar; 65(3):476-82.
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Diaz KM, Veerabhadrappa P, Brown MD, Whited MC, Dubbert PM, Hickson DA. Prevalence, Determinants, and Clinical Significance of Masked Hypertension in a Population-Based Sample of African Americans: The Jackson Heart Study. Am J Hypertens. 2015 Jul; 28(7):900-8.
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Sporkov? A, J?chov? S, Huskov? Z, Kopkan L, Nishiyama A, Hwang SH, Hammock BD, Imig JD, Kompanowska-Jezierska E, Sadowski J, Kramer HJ, Cervenka L. Different mechanisms of acute versus long-term antihypertensive effects of soluble epoxide hydrolase inhibition: studies in Cyp1a1-Ren-2 transgenic rats. Clin Exp Pharmacol Physiol. 2014 Dec; 41(12):1003-13.
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Pakravan M, Yazdani S. Author reply: To PMID 24819857. Ophthalmology. 2014 Dec; 121(12):e69.
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Bano M, Kanaan UB, Ehrlich AC, McCracken C, Morrow G, Oster ME, Sachdeva R. Improvement in Tricuspid Annular Plane Systolic Excursion with Pulmonary Hypertension Therapy in Pediatric Patients. Echocardiography. 2015 Aug; 32(8):1228-32.
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