 Alkylating Agents
"Alkylating Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases.
| Descriptor ID |
D000477
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| MeSH Number(s) |
D27.505.519.124 D27.888.569.035
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Alkylating Agents".
Below are MeSH descriptors whose meaning is more specific than "Alkylating Agents".
This graph shows the total number of publications written about "Alkylating Agents" by people in UAMS Profiles by year, and whether "Alkylating Agents" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2011 | 1 | 1 | 2 | | 2008 | 0 | 1 | 1 | | 2004 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2000 | 0 | 1 | 1 | | 1996 | 1 | 0 | 1 | | 1993 | 1 | 0 | 1 |
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Below are the most recent publications written about "Alkylating Agents" by people in Profiles over the past ten years.
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Swaminathan SS, Jammal AA, Medeiros FA, Gedde SJ. Visual Field Outcomes in the Primary Tube Versus Trabeculectomy Study. Ophthalmology. 2024 Oct; 131(10):1157-1163.
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Kreher MA, Konda S, Noland MMB, Longo MI, Valdes-Rodriguez R. Risk of melanoma and nonmelanoma skin cancer with immunosuppressants, part II: Methotrexate, alkylating agents, biologics, and small molecule inhibitors. J Am Acad Dermatol. 2023 Mar; 88(3):534-542.
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Pakbin M, Khabazkhoob M, Pakravan M, Fotouhi A, Jafarzadehpour E, Aghamirsalim M, Seyedian MA, Hashemi H. Duration of topical steroid application after photorefractive keratectomy with mitomycin C. J Cataract Refract Surg. 2020 04; 46(4):622-632.
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Esfandiari H, Pakravan M, Yazdani S, Doozandeh A, Yaseri M, Conner IP. Treatment Outcomes of Mitomycin C-Augmented Trabeculectomy, Sub-Tenon Injection versus Soaked Sponges, after 3 Years of Follow-up: A Randomized Clinical Trial. Ophthalmol Glaucoma. 2018 Jul - Aug; 1(1):66-74.
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Yung ES, Moster MR, Sanvicente C, Pluta J, Rahmatnejad K, Patel AS, Williams A, Abramowitz B, Katz LJ, Pro M. Trypan Blue for the Assessment of Filtering Bleb Function During Cataract Surgery. J Glaucoma. 2018 03; 27(3):246-250.
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Pakravan M, Esfandiari H, Yazdani S, Douzandeh A, Amouhashemi N, Yaseri M, Pakravan P. Mitomycin C-augmented trabeculectomy: subtenon injection versus soaked sponges: a randomised clinical trial. Br J Ophthalmol. 2017 09; 101(9):1275-1280.
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Yazdani S, Mahboobipour H, Pakravan M, Doozandeh A, Ghahari E. Adjunctive Mitomycin C or Amniotic Membrane Transplantation for Ahmed Glaucoma Valve Implantation: A Randomized Clinical Trial. J Glaucoma. 2016 05; 25(5):415-21.
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Mercer KE, Pulliam C, Hennings L, Lai K, Cleves M, Jones E, Drake RR, Ronis M. Soy Protein Isolate Protects Against Ethanol-Mediated Tumor Progression in Diethylnitrosamine-Treated Male Mice. Cancer Prev Res (Phila). 2016 06; 9(6):466-75.
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Bettis DI, Morshedi RG, Chaya C, Goldsmith J, Crandall A, Zabriskie N. Trabeculectomy With Mitomycin C or Ahmed Valve Implantation in Eyes With Uveitic Glaucoma. J Glaucoma. 2015 Oct-Nov; 24(8):591-9.
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Pakravan M, Alvani A, Yazdani S, Esfandiari H, Yaseri M. Intraocular lens power changes after mitomycin trabeculectomy. Eur J Ophthalmol. 2015 Nov-Dec; 25(6):478-82.
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