 Mutagens
"Mutagens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes.
| Descriptor ID |
D009153
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| MeSH Number(s) |
D27.888.569.468
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Mutagens".
Below are MeSH descriptors whose meaning is more specific than "Mutagens".
This graph shows the total number of publications written about "Mutagens" by people in UAMS Profiles by year, and whether "Mutagens" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 1 | 1 | 2 | | 2020 | 1 | 1 | 2 | | 2019 | 2 | 1 | 3 | | 2018 | 2 | 0 | 2 | | 2016 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2012 | 2 | 1 | 3 | | 2010 | 1 | 1 | 2 | | 2008 | 0 | 2 | 2 | | 2006 | 0 | 2 | 2 | | 2005 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 | | 2003 | 1 | 1 | 2 | | 2002 | 3 | 1 | 4 | | 2001 | 0 | 2 | 2 | | 1999 | 1 | 0 | 1 | | 1997 | 0 | 1 | 1 | | 1993 | 1 | 0 | 1 | | 1992 | 0 | 1 | 1 | | 1991 | 1 | 0 | 1 | | 1989 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mutagens" by people in Profiles over the past ten years.
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Wang Y, Mittelstaedt RA, Wynne R, Chen Y, Cao X, Muskhelishvili L, Davis K, Robison TW, Sun W, Schmidt EK, Smith TH, Norgaard ZK, Valentine CC, Yaplee J, Williams LN, Salk JJ, Heflich RH. Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing. Environ Mol Mutagen. 2021 06; 62(5):306-318.
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Maura F, Weinhold N, Diamond B, Kazandjian D, Rasche L, Morgan G, Landgren O. The mutagenic impact of melphalan in multiple myeloma. Leukemia. 2021 08; 35(8):2145-2150.
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H?lzl-Armstrong L, Kucab JE, Zwart EP, Luijten M, Phillips DH, Arlt VM. Mutagenicity of N-hydroxy-4-aminobiphenyl in human TP53 knock-in (Hupki) mouse embryo fibroblasts. Environ Mol Mutagen. 2021 04; 62(4):252-264.
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H?lzl-Armstrong L, Kucab JE, Moody S, Zwart EP, Loutkotov? L, Duffy V, Luijten M, Gamboa da Costa G, Stratton MR, Phillips DH, Arlt VM. Mutagenicity of acrylamide and glycidamide in human TP53 knock-in (Hupki) mouse embryo fibroblasts. Arch Toxicol. 2020 12; 94(12):4173-4196.
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Hayes M, Ferruzzi MG. Update on the bioavailability and chemopreventative mechanisms of dietary chlorophyll derivatives. Nutr Res. 2020 09; 81:19-37.
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Demir E, Qin T, Li Y, Zhang Y, Guo X, Ingle T, Yan J, Orza AI, Biris AS, Ghorai S, Zhou T, Chen T. Cytotoxicity and genotoxicity of cadmium oxide nanoparticles evaluated using in vitro assays. Mutat Res Genet Toxicol Environ Mutagen. 2020 Feb - Mar; 850-851:503149.
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Phillips DH, Arlt VM. 32P-Postlabeling Analysis of DNA Adducts. Methods Mol Biol. 2020; 2102:291-302.
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Sborchia M, De Prez EG, Antoine MH, Bienfait L, Indra R, Valbuena G, Phillips DH, Nortier JL, Stiborov? M, Keun HC, Arlt VM. The impact of p53 on aristolochic acid I-induced nephrotoxicity and DNA damage in vivo and in vitro. Arch Toxicol. 2019 11; 93(11):3345-3366.
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Lewis L, Borowa-Mazgaj B, de Conti A, Chappell GA, Luo YS, Bodnar W, Konganti K, Wright FA, Threadgill DW, Chiu WA, Pogribny IP, Rusyn I. Population-Based Analysis of DNA Damage and Epigenetic Effects of 1,3-Butadiene in the Mouse. Chem Res Toxicol. 2019 05 20; 32(5):887-898.
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de Conti A, Tryndyak V, VonTungeln LS, Churchwell MI, Beland FA, Antunes AMM, Pogribny IP. Genotoxic and Epigenotoxic Alterations in the Lung and Liver of Mice Induced by Acrylamide: A 28 Day Drinking Water Study. Chem Res Toxicol. 2019 05 20; 32(5):869-877.
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Seo JE, Tryndyak V, Wu Q, Dreval K, Pogribny I, Bryant M, Zhou T, Robison TW, Mei N, Guo X. Quantitative comparison of in vitro genotoxicity between metabolically competent HepaRG cells and HepG2 cells using the high-throughput high-content CometChip assay. Arch Toxicol. 2019 05; 93(5):1433-1448.
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Lewis L, Chappell GA, Kobets T, O'Brian BE, Sangaraju D, Kosyk O, Bodnar W, Tretyakova NY, Pogribny IP, Rusyn I. Sex-specific differences in genotoxic and epigenetic effects of 1,3-butadiene among mouse tissues. Arch Toxicol. 2019 03; 93(3):791-800.
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Acevedo-Whitehouse K, Cole KJ, Phillips DH, Jepson PD, Deaville R, Arlt VM. Hepatic DNA damage in harbour porpoises (Phocoena phocoena) stranded along the English and Welsh coastlines. Environ Mol Mutagen. 2018 08; 59(7):613-624.
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Slavov SH, Stoyanova-Slavova I, Mattes W, Beger RD, Br?schweiler BJ. Computational identification of structural factors affecting the mutagenic potential of aromatic amines: study design and experimental validation. Arch Toxicol. 2018 07; 92(7):2369-2384.
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Imanikia S, Galea F, Nagy E, Phillips DH, St?rzenbaum SR, Arlt VM. The application of the comet assay to assess the genotoxicity of environmental pollutants in the nematode Caenorhabditis elegans. Environ Toxicol Pharmacol. 2016 Jul; 45:356-61.
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Chappell G, Pogribny IP, Guyton KZ, Rusyn I. Epigenetic alterations induced by genotoxic occupational and environmental human chemical carcinogens: A systematic literature review. Mutat Res Rev Mutat Res. 2016 Apr-Jun; 768:27-45.
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Singleton B, Turner J, Walter L, Lathan N, Thorpe D, Ogbevoen P, Daye J, Alcorn D, Wilson S, Semien J, Richard T, Johnson T, McCabe K, Estrada JJ, Galvez F, Velasco C, Reiss K. Environmental stress in the Gulf of Mexico and its potential impact on public health. Environ Res. 2016 Apr; 146:108-15.
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Kucab JE, Zwart EP, van Steeg H, Luijten M, Schmeiser HH, Phillips DH, Arlt VM. TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblasts. DNA Repair (Amst). 2016 Mar; 39:21-33.
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Nik-Zainal S, Kucab JE, Morganella S, Glodzik D, Alexandrov LB, Arlt VM, Weninger A, Hollstein M, Stratton MR, Phillips DH. The genome as a record of environmental exposure. Mutagenesis. 2015 Nov; 30(6):763-70.
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Kucab JE, van Steeg H, Luijten M, Schmeiser HH, White PA, Phillips DH, Arlt VM. TP53 mutations induced by BPDE in Xpa-WT and Xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts. Mutat Res. 2015 Mar; 773:48-62.
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Zeiger E, Gollapudi B, Aardema MJ, Auerbach S, Boverhof D, Custer L, Dedon P, Honma M, Ishida S, Kasinski AL, Kim JH, Manjanatha MG, Marlowe J, Pfuhler S, Pogribny I, Slikker W, Stankowski LF, Tanir JY, Tice R, van Benthem J, White P, Witt KL, Thybaud V. Opportunities to integrate new approaches in genetic toxicology: an ILSI-HESI workshop report. Environ Mol Mutagen. 2015 Apr; 56(3):277-85.
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