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Matthew Jorgenson

TitleAssistant Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentMicrobiology & Immunology, College of Medicine
Address325 S. Elm St.
Mail Slot # 511
Little Rock AR 72205
Phone501-526-6805
ORCID ORCID Icon0000-0003-1351-7730 Additional info
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    Collapse Research 
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    R35GM154672     (JORGENSON, MATTHEW)Jun 10, 2024 - Apr 30, 2029
    NIH/Nat. Inst. of General Medical Sciences
    Manipulating undecaprenyl phosphate levels to decipher mechanisms of competing cell envelope assembly pathways in Escherichia coli
    Role: Principal Investigator
    P30GM145393     (SMELTZER, MARK S)May 5, 2022 - Apr 30, 2027
    NIH
    Center for Microbial Pathogenesis and Host Inflammatory Responses
    Role: Co-Investigator
    R01GM123251     (TROUTMAN, JERRY M)May 1, 2017 - Aug 31, 2024
    NIH
    In vitro and cellular tools for complex polysaccharide biosynthesis
    Role: Co-Investigator
    P20GM103625     (SMELTZER, MARK S)Aug 15, 2012 - Apr 30, 2022
    NIH
    Center for Microbial Pathogenesis and Host Inflammatory Responses
    Role: Co-Investigator
    P00007     (YOUNG, KEVIN)Mar 15, 2010 - Dec 14, 2015
    US Department of the Army
    Composition and characteristics of cell poles as a measure of bacterial growth history
    Role: Co-Investigator
    R01GM061019     (VOTH, DANIEL E)Mar 1, 2000 - Dec 31, 2021
    NIH
    Bacterial cell wall synthesis, shape and septation
    Role: Co-Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Lei MG, Jorgenson MA, Robbs EJ, Black IM, Archer-Hartmann S, Shalygin S, Azadi P, Lee CY. Characterization of Ssc, an N-acetylgalactosamine-containing Staphylococcus aureus surface polysaccharide. J Bacteriol. 2024 05 23; 206(5):e0004824. PMID: 38712944.
      View in: PubMed
    2. Kay EJ, Dooda MK, Bryant JC, Reid AJ, Wren BW, Troutman JM, Jorgenson MA. Engineering Escherichia coli for increased Und-P availability leads to material improvements in glycan expression technology. Microb Cell Fact. 2024 Mar 01; 23(1):72. PMID: 38429691.
      View in: PubMed
    3. Reid AJ, Eade CR, Jones KJ, Jorgenson MA, Troutman JM. Tracking Colanic Acid Repeat Unit Formation from Stepwise Biosynthesis Inactivation in Escherichia coli. Biochemistry. 2021 07 13; 60(27):2221-2230. PMID: 34159784.
      View in: PubMed
    4. Eade CR, Wallen TW, Gates CE, Oliverio CL, Scarbrough BA, Reid AJ, Jorgenson MA, Young KD, Troutman JM. Making the Enterobacterial Common Antigen Glycan and Measuring Its Substrate Sequestration. ACS Chem Biol. 2021 04 16; 16(4):691-700. PMID: 33740380.
      View in: PubMed
    5. Jorgenson MA, Bryant JC. A genetic screen to identify factors affected by undecaprenyl phosphate recycling uncovers novel connections to morphogenesis in Escherichia coli. Mol Microbiol. 2021 02; 115(2):191-207. PMID: 32979869.
      View in: PubMed
    6. Jorgenson MA, MacCain WJ, Meberg BM, Kannan S, Bryant JC, Young KD. Simultaneously inhibiting undecaprenyl phosphate production and peptidoglycan synthases promotes rapid lysis in Escherichia coli. Mol Microbiol. 2019 07; 112(1):233-248. PMID: 31022322.
      View in: PubMed
    7. Jorgenson MA, Young KD. YtfB, an OapA Domain-Containing Protein, Is a New Cell Division Protein in Escherichia coli. J Bacteriol. 2018 07 01; 200(13). PMID: 29686141.
      View in: PubMed
    8. Jorgenson MA. Bacterial Size: Tuning In to a Clearer Connection. Curr Biol. 2017 11 20; 27(22):R1216-R1218. PMID: 29161559.
      View in: PubMed
    9. Yahashiri A, Jorgenson MA, Weiss DS. The SPOR Domain, a Widely Conserved Peptidoglycan Binding Domain That Targets Proteins to the Site of Cell Division. J Bacteriol. 2017 07 15; 199(14). PMID: 28396350.
      View in: PubMed
    10. Ranjit DK, Jorgenson MA, Young KD. PBP1B Glycosyltransferase and Transpeptidase Activities Play Different Essential Roles during the De Novo Regeneration of Rod Morphology in Escherichia coli. J Bacteriol. 2017 04 01; 199(7). PMID: 28096447.
      View in: PubMed
    11. Jorgenson MA, Young KD. Interrupting Biosynthesis of O Antigen or the Lipopolysaccharide Core Produces Morphological Defects in Escherichia coli by Sequestering Undecaprenyl Phosphate. J Bacteriol. 2016 11 15; 198(22):3070-3079. PMID: 27573014.
      View in: PubMed
    12. Jorgenson MA, Kannan S, Laubacher ME, Young KD. Dead-end intermediates in the enterobacterial common antigen pathway induce morphological defects in Escherichia coli by competing for undecaprenyl phosphate. Mol Microbiol. 2016 Apr; 100(1):1-14. PMID: 26593043.
      View in: PubMed
    13. Yahashiri A, Jorgenson MA, Weiss DS. Bacterial SPOR domains are recruited to septal peptidoglycan by binding to glycan strands that lack stem peptides. Proc Natl Acad Sci U S A. 2015 Sep 08; 112(36):11347-52. PMID: 26305949.
      View in: PubMed
    14. Jorgenson MA, Chen Y, Yahashiri A, Popham DL, Weiss DS. The bacterial septal ring protein RlpA is a lytic transglycosylase that contributes to rod shape and daughter cell separation in Pseudomonas aeruginosa. Mol Microbiol. 2014 Jul; 93(1):113-28. PMID: 24806796.
      View in: PubMed
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