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Mei Lei

TitlePrincipal Staff Scientist
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentMicrobiology & Immunology, College of Medicine
DivisionMBIM Lee Lab
Address509 Biomedical Research II
200 South Cedar
Mail Slot # 511
Little Rock AR 72202
Phone501-526-7937
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    Collapse Research 
    Collapse research activities and funding
    R21AI168850     (LEE, CHIA Y.)Mar 1, 2023 - Feb 28, 2025
    NIH
    Modulation of Agr system by ClpC chaperone in S. aureus
    Role: Co-Investigator
    R21AI159212     (LEE, CHIA Y.)Mar 16, 2021 - Feb 29, 2024
    NIH
    Characterization of a novel S. aureus biofilm polysaccharide
    Role: Co-Investigator
    R01AI113766     (LEE, CHIA Y.)Mar 1, 2015 - Feb 28, 2021
    NIH
    Virulence gene regulation in Staphylococcus aureus
    Role: Co-Investigator
    R56AI113766     (LEE, CHIA Y.)Jul 10, 2014 - Feb 28, 2015
    NIH
    Virulence gene regulation in Staphylococcus aureus
    Role: Co-Investigator
    R21AI112028     (LEE, CHIA Y.)Apr 7, 2014 - Mar 31, 2017
    NIH
    Proteomic analysis of S aureus biofilm in vivo
    Role: Co-Investigator
    R01AI067857     (LEE, CHIA Y.)Jul 5, 2007 - Jun 30, 2014
    NIH
    Regulation of Staphylococcus aureus biofilm by Rbf
    Role: Co-Investigator
    R01AI054607     (LEE, CHIA Y.)Apr 1, 2003 - Mar 31, 2009
    NIH
    Global regulation by mgr in S. aureus
    Role: Co-Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Lei MG, Jorgenson MA, Robbs EJ, Black IM, Archer-Hartmann S, Shalygin S, Azadi P, Lee CY. Characterization of Ssc, an N-acetylgalactosamine-containing Staphylococcus aureus surface polysaccharide. J Bacteriol. 2024 05 23; 206(5):e0004824. PMID: 38712944.
      View in: PubMed
    2. Lei MG, Lee CY. Regulation of Staphylococcal Capsule by SarZ is SigA-Dependent. J Bacteriol. 2022 08 16; 204(8):e0015222. PMID: 35862799.
      View in: PubMed
    3. Lei MG, Gupta RK, Lee CY. A Rat Model of Orthopedic Implant-Associated Infection for Identification of Staphylococcal Biofilm Proteins. Methods Mol Biol. 2021; 2341:117-125. PMID: 34264467.
      View in: PubMed
    4. Lei MG, Lee CY. MgrA Activates Staphylococcal Capsule via SigA-Dependent Promoter. J Bacteriol. 2020 12 18; 203(2). PMID: 33077637.
      View in: PubMed
    5. Lei MG, Gudeta DD, Luong TT, Lee CY. MgrA Negatively Impacts Staphylococcus aureus Invasion by Regulating Capsule and FnbA. Infect Immun. 2019 12; 87(12). PMID: 31591167.
      View in: PubMed
    6. Gudeta DD, Lei MG, Lee CY. Contribution of hla Regulation by SaeR to Staphylococcus aureus USA300 Pathogenesis. Infect Immun. 2019 09; 87(9). PMID: 31209148.
      View in: PubMed
    7. Lei MG, Lee CY. Repression of Capsule Production by XdrA and CodY in Staphylococcus aureus. J Bacteriol. 2018 09 15; 200(18). PMID: 29967117.
      View in: PubMed
    8. Lei MG, Gupta RK, Lee CY. Proteomics of Staphylococcus aureus biofilm matrix in a rat model of orthopedic implant-associated infection. PLoS One. 2017; 12(11):e0187981. PMID: 29121106.
      View in: PubMed
    9. Lei MG, Lee CY. RbsR Activates Capsule but Represses the rbsUDK Operon in Staphylococcus aureus. J Bacteriol. 2015 Dec; 197(23):3666-75. PMID: 26350136.
      View in: PubMed
    10. Cue D, Junecko JM, Lei MG, Blevins JS, Smeltzer MS, Lee CY. SaeRS-dependent inhibition of biofilm formation in Staphylococcus aureus Newman. PLoS One. 2015; 10(4):e0123027. PMID: 25853849.
      View in: PubMed
    11. Graham JW, Lei MG, Lee CY. Trapping and identification of cellular substrates of the Staphylococcus aureus ClpC chaperone. J Bacteriol. 2013 Oct; 195(19):4506-16. PMID: 23913326.
      View in: PubMed
    12. Cue D, Lei MG, Lee CY. Activation of sarX by Rbf is required for biofilm formation and icaADBC expression in Staphylococcus aureus. J Bacteriol. 2013 Apr; 195(7):1515-24. PMID: 23354746.
      View in: PubMed
    13. Cue D, Lei MG, Lee CY. Genetic regulation of the intercellular adhesion locus in staphylococci. Front Cell Infect Microbiol. 2012; 2:38. PMID: 23061050.
      View in: PubMed
    14. Lei MG, Cue D, Alba J, Junecko J, Graham JW, Lee CY. A single copy integration vector that integrates at an engineered site on the Staphylococcus aureus chromosome. BMC Res Notes. 2012 Jan 05; 5:5. PMID: 22221385.
      View in: PubMed
    15. Lei MG, Cue D, Roux CM, Dunman PM, Lee CY. Rsp inhibits attachment and biofilm formation by repressing fnbA in Staphylococcus aureus MW2. J Bacteriol. 2011 Oct; 193(19):5231-41. PMID: 21804010.
      View in: PubMed
    16. Cue D, Lei MG, Luong TT, Kuechenmeister L, Dunman PM, O'Donnell S, Rowe S, O'Gara JP, Lee CY. Rbf promotes biofilm formation by Staphylococcus aureus via repression of icaR, a negative regulator of icaADBC. J Bacteriol. 2009 Oct; 191(20):6363-73. PMID: 19684134.
      View in: PubMed
    17. Zhu Y, Xiong YQ, Sadykov MR, Fey PD, Lei MG, Lee CY, Bayer AS, Somerville GA. Tricarboxylic acid cycle-dependent attenuation of Staphylococcus aureus in vivo virulence by selective inhibition of amino acid transport. Infect Immun. 2009 Oct; 77(10):4256-64. PMID: 19667045.
      View in: PubMed
    18. Cue, D, Lei MG, Luong, TT, Kuechenmeister, L, Dunman, PM, O'Donnell, S, Rowe, S, O'Gara, JP, Lee, CY. Rbf promotes biofilm formation by Staphylococcus aureus via repression of icsR, a negative regulator of icaADBC. J. BACTERIOL. 2009; (191):6363-6373.
    19. Luong, TT, Lei MG, Lee, CY, Lei M. Staphylococcus aureus Rbf activates biofilm formation in vitro and promotes virulence in a murine foreigh body infection model. Infect Immun. 2009; 77(1):335-340.
    20. Zhu, Y, Xioung, YQ, Sadykov, MR, Fey, PD, Lei MG, Lee, CY, Bayer, AS, Somerville, GA. Tricarboxylic acid. cycle-dependent attenuation of Staphlococcus aureus in vivo virulence by selective inhibition of amino acid transport. Infect Immun. 2009; 77(10):4256-4264.
    21. Luong TT, Lei MG, Lee CY. Staphylococcus aureus Rbf activates biofilm formation in vitro and promotes virulence in a murine foreign body infection model. Infect Immun. 2009 Jan; 77(1):335-40. PMID: 18955475.
      View in: PubMed
    22. Lei MG, Tan X, Qureshi N, Morrison DC. Regulation of cellular caveolin-1 protein expression in murine macrophages by microbial products. Infect Immun. 2005 Dec; 73(12):8136-43. PMID: 16299308.
      View in: PubMed
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