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Gabriella ten Have

TitleAssociate Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentCOM | Peds Developmental Nutrition
Address4301 W Markham
Little Rock AR 72205
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Morse R, Ten Have GAM, Thaden JJ, Engelen MPKJ, Rice S, Hagve M, Deutz NEP. The role of adipose and muscle tissue breakdown on interorgan energy substrate fluxes in a Pseudomonas aeruginosa induced sepsis model in female pigs. Physiol Rep. 2025 Jan; 13(1):e70129. PMID: 39753379.
      View in: PubMed
    2. Rice SA, Ten Have GAM, Engelen MPKJ, Deutz NEP. Muscle protein catabolism and splanchnic arginine consumption drive arginine dysregulation during Pseudomonas Aeruginosa induced early acute sepsis in swine. Am J Physiol Gastrointest Liver Physiol. 2024 Sep 03. PMID: 39224070.
      View in: PubMed
    3. Sobhi HF, Mercer KE, Lan RS, Yeruva L, Ten Have GAM, Deutz NEP, Piccolo BD, Deb?dat J, Pack LM, Adams SH. Novel odd-chain cyclopropane fatty acids: detection in a mammalian lipidome and uptake by hepatosplanchnic tissues. J Lipid Res. 2024 Oct; 65(10):100632. PMID: 39182606.
      View in: PubMed
    4. Engelen MPKJ, Simbo SY, Ruebush LE, Thaden JJ, Ten Have GAM, Harrykissoon RI, Zachria AJ, Calder PC, Pereira SL, Deutz NEP. Functional and metabolic effects of omega-3 polyunsaturated fatty acid supplementation and the role of ?-hydroxy-?-methylbutyrate addition in chronic obstructive pulmonary disease: A randomized clinical trial. Clin Nutr. 2024 Sep; 43(9):2263-2278. PMID: 39181037.
      View in: PubMed
    5. Deutz NEP, Singer P, Wierzchowska-McNew RA, Viana MV, Ben-David IA, Pantet O, Thaden JJ, Ten Have GAM, Engelen MPKJ, Berger MM. Females have a different metabolic response to critical illness, measured by comprehensive amino acid flux analysis. Metabolism. 2023 05; 142:155400. PMID: 36717057.
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    6. Wierzchowska-McNew RA, Engelen MPKJ, Thaden JJ, Ten Have GAM, Deutz NEP. Obesity- and sex-related metabolism of arginine and nitric oxide in adults. Am J Clin Nutr. 2022 12 19; 116(6):1610-1620. PMID: 36166849.
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    7. Ten Have GAM, Engelen MPKJ, Deutz NEP. In-vivo production of branched-chain amino acids, branched-chain keto acids, and ?-hydroxy ?-methylbutyric acid. Curr Opin Clin Nutr Metab Care. 2022 01 01; 25(1):43-49. PMID: 34798641.
      View in: PubMed
    8. Viana MV, Becce F, Pantet O, Schmidt S, Bagnoud G, Thaden JJ, Ten Have GAM, Engelen MPKJ, Voidey A, Deutz NEP, Berger MM. Impact of ?-hydroxy-?-methylbutyrate (HMB) on muscle loss and protein metabolism in critically ill patients: A RCT. Clin Nutr. 2021 08; 40(8):4878-4887. PMID: 34358832.
      View in: PubMed
    9. Deutz NEP, Singer P, Wierzchowska-McNew RA, Viana MV, Ben-David IA, Pantet O, Thaden JJ, Ten Have GAM, Engelen MPKJ, Berger MM. Comprehensive metabolic amino acid flux analysis in critically ill patients. Clin Nutr. 2021 05; 40(5):2876-2897. PMID: 33946038.
      View in: PubMed
    10. Cross KM, Granados JZ, Ten Have GAM, Thaden JJ, Engelen MPKJ, Lightfoot JT, Deutz NEP. Correction: Protein fractional synthesis rates within tissues of high- and low-active mice. PLoS One. 2021; 16(2):e0248081. PMID: 33630961.
      View in: PubMed
    11. Ten Have GAM, Jansen L, Schooneman MG, Engelen MPKJ, Deutz NEP. Metabolic flux analysis of branched-chain amino and keto acids (BCAA, BCKA) and ?-hydroxy ?-methylbutyric acid across multiple organs in the pig. Am J Physiol Endocrinol Metab. 2021 03 01; 320(3):E629-E640. PMID: 33522397.
      View in: PubMed
    12. Rice SA, Ten Have GAM, Reisz JA, Gehrke S, Stefanoni D, Frare C, Barati Z, Coker RH, D'Alessandro A, Deutz NEP, Drew KL. Nitrogen recycling buffers against ammonia toxicity from skeletal muscle breakdown in hibernating arctic ground squirrels. Nat Metab. 2020 12; 2(12):1459-1471. PMID: 33288952.
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    13. Cross KM, Granados JZ, Ten Have GAM, Thaden JJ, Engelen MPKJ, Lightfoot JT, Deutz NEP. Protein fractional synthesis rates within tissues of high- and low-active mice. PLoS One. 2020; 15(11):e0242926. PMID: 33253250.
      View in: PubMed
    14. Ligthart-Melis GC, Engelen MPKJ, Simbo SY, Ten Have GAM, Thaden JJ, Cynober L, Deutz NEP. Metabolic Consequences of Supplemented Methionine in a Clinical Context. J Nutr. 2020 10 01; 150(Suppl 1):2538S-2547S. PMID: 33000166.
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    15. Granados JZ, Ten Have GAM, Letsinger AC, Thaden JJ, Engelen MPKJ, Lightfoot JT, Deutz NEP. Activated whole-body arginine pathway in high-active mice. PLoS One. 2020; 15(6):e0235095. PMID: 32589680.
      View in: PubMed
    16. Mercer KE, Ten Have GAM, Pack L, Lan R, Deutz NEP, Adams SH, Piccolo BD. Net release and uptake of xenometabolites across intestinal, hepatic, muscle, and renal tissue beds in healthy conscious pigs. Am J Physiol Gastrointest Liver Physiol. 2020 08 01; 319(2):G133-G141. PMID: 32538141.
      View in: PubMed
    17. Engelen MPKJ, Jonker R, Thaden JJ, Ten Have GAM, Jeon MS, Dasarathy S, Deutz NEP. Comprehensive metabolic flux analysis to explain skeletal muscle weakness in COPD. Clin Nutr. 2020 10; 39(10):3056-3065. PMID: 32035752.
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    18. Engelen MPKJ, Ten Have GAM, Thaden JJ, Deutz NEP. New advances in stable tracer methods to assess whole-body protein and amino acid metabolism. Curr Opin Clin Nutr Metab Care. 2019 09; 22(5):337-346. PMID: 31192825.
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    19. Ilaiwy A, Ten Have GAM, Bain JR, Muehlbauer MJ, O'Neal SK, Berthiaume JM, Parry TL, Deutz NE, Willis MS. Identification of Metabolic Changes in Ileum, Jejunum, Skeletal Muscle, Liver, and Lung in a Continuous I.V. Pseudomonas aeruginosa Model of Sepsis Using Nontargeted Metabolomics Analysis. Am J Pathol. 2019 09; 189(9):1797-1813. PMID: 31439155.
      View in: PubMed
    20. Deutz NEP, Thaden JJ, Ten Have GAM, Walker DK, Engelen MPKJ. Metabolic phenotyping using kinetic measurements in young and older healthy adults. Metabolism. 2018 01; 78:167-178. PMID: 28986165.
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    21. Ten Have GAM, Deutz RCI, Engelen MPKJ, Wolfe RR, Deutz NEP. Characteristics of a Pseudomonas aeruginosa induced porcine sepsis model for multi-organ metabolic flux measurements. Lab Anim. 2018 Apr; 52(2):163-175. PMID: 28679339.
      View in: PubMed
    22. Eggink HM, van Nierop FS, Schooneman MG, Boelen A, Kalsbeek A, Koehorst M, Ten Have GAM, de Brauw LM, Groen AK, Romijn JA, Deutz NEP, Soeters MR. Transhepatic bile acid kinetics in pigs and humans. Clin Nutr. 2018 08; 37(4):1406-1414. PMID: 28669667.
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    23. Kumar A, Davuluri G, Silva RNE, Engelen MPKJ, Ten Have GAM, Prayson R, Deutz NEP, Dasarathy S. Ammonia lowering reverses sarcopenia of cirrhosis by restoring skeletal muscle proteostasis. Hepatology. 2017 06; 65(6):2045-2058. PMID: 28195332.
      View in: PubMed
    24. Ten Have GAM, Engelen MPKJ, Wolfe RR, Deutz NEP. Phenylalanine isotope pulse method to measure effect of sepsis on protein breakdown and membrane transport in the pig. Am J Physiol Endocrinol Metab. 2017 06 01; 312(6):E519-E529. PMID: 28292760.
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    25. Bosoi CR, Oliveira MM, Ochoa-Sanchez R, Tremblay M, Ten Have GA, Deutz NE, Rose CF, Bemeur C. The bile duct ligated rat: A relevant model to study muscle mass loss in cirrhosis. Metab Brain Dis. 2017 04; 32(2):513-518. PMID: 27981407.
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    26. Ten Have GA, van der Pijl PC, Kies AK, Deutz NE. Enhanced Lacto-Tri-Peptide Bio-Availability by Co-Ingestion of Macronutrients. PLoS One. 2015; 10(6):e0130638. PMID: 26098114.
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    27. Schooneman MG, Ten Have GA, van Vlies N, Houten SM, Deutz NE, Soeters MR. Transorgan fluxes in a porcine model reveal a central role for liver in acylcarnitine metabolism. Am J Physiol Endocrinol Metab. 2015 Aug 01; 309(3):E256-64. PMID: 26037250.
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    28. Tsien C, Davuluri G, Singh D, Allawy A, Ten Have GA, Thapaliya S, Schulze JM, Barnes D, McCullough AJ, Engelen MP, Deutz NE, Dasarathy S. Metabolic and molecular responses to leucine-enriched branched chain amino acid supplementation in the skeletal muscle of alcoholic cirrhosis. Hepatology. 2015 Jun; 61(6):2018-29. PMID: 25613922.
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    29. Luiking YC, Ten Have GA, Wolfe RR, Deutz NE. Arginine de novo and nitric oxide production in disease states. Am J Physiol Endocrinol Metab. 2012 Nov 15; 303(10):E1177-89. PMID: 23011059.
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    30. Sharma V, Ten Have GA, Ytrebo L, Sen S, Rose CF, Dalton RN, Turner C, Revhaug A, van-Eijk HM, Deutz NE, Jalan R, Mookerjee RP, Davies NA. Nitric oxide and L-arginine metabolism in a devascularized porcine model of acute liver failure. Am J Physiol Gastrointest Liver Physiol. 2012 Aug 01; 303(3):G435-41. PMID: 22421619.
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    31. Ten Have GA, Engelen MP, Soeters PB, Deutz NE. Absence of post-prandial gut anabolism after intake of a low quality protein meal. Clin Nutr. 2012 Apr; 31(2):273-82. PMID: 22001026.
      View in: PubMed
    32. He Y, Hakvoort TBM, K?hler SE, Vermeulen JLM, de Waart DR, de Theije C, Ten Have GAM, van Eijk HMH, Kunne C, Labruyere WT, Houten SM, Sokolovic M, Ruijter JM, Deutz NEP, Lamers WH. Glutamine synthetase in muscle is required for glutamine production during fasting and extrahepatic ammonia detoxification. J Biol Chem. 2010 Mar 26; 285(13):9516-9524. PMID: 20064933.
      View in: PubMed
    33. van der Pijl PC, Kies AK, Ten Have GA, Duchateau GS, Deutz NE. Pharmacokinetics of proline-rich tripeptides in the pig. Peptides. 2008 Dec; 29(12):2196-202. PMID: 18789987.
      View in: PubMed
    34. Ten Have GA, Engelen MP, Luiking YC, Deutz NE. Absorption kinetics of amino acids, peptides, and intact proteins. Int J Sport Nutr Exerc Metab. 2007 Aug; 17 Suppl:S23-36. PMID: 18577772.
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    35. Ytreb? LM, Sen S, Rose C, Davies NA, Nedredal GI, Fuskevaag OM, Ten Have GA, Prinzen FW, Williams R, Deutz NE, Jalan R, Revhaug A. Systemic and regional hemodynamics in pigs with acute liver failure and the effect of albumin dialysis. Scand J Gastroenterol. 2006 Nov; 41(11):1350-60. PMID: 17060130.
      View in: PubMed
    36. Ytreb? LM, Sen S, Rose C, Ten Have GA, Davies NA, Hodges S, Nedredal GI, Romero-Gomez M, Williams R, Revhaug A, Jalan R, Deutz NE. Interorgan ammonia, glutamate, and glutamine trafficking in pigs with acute liver failure. Am J Physiol Gastrointest Liver Physiol. 2006 Sep; 291(3):G373-81. PMID: 16782695.
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    37. Boelens PG, Melis GC, van Leeuwen PA, ten Have GA, Deutz NE. Route of administration (enteral or parenteral) affects the contribution of L-glutamine to de novo L-arginine synthesis in mice: a stable-isotope study. Am J Physiol Endocrinol Metab. 2006 Oct; 291(4):E683-90. PMID: 16684848.
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    38. Braulio VB, Ten Have GA, Vissers YL, Deutz NE. Time course of nitric oxide production after endotoxin challenge in mice. Am J Physiol Endocrinol Metab. 2004 Nov; 287(5):E912-8. PMID: 15265764.
      View in: PubMed
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