 rac1 GTP-Binding Protein
"rac1 GTP-Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A rac GTP-binding protein involved in regulating actin filaments at the plasma membrane. It controls the development of filopodia and lamellipodia in cells and thereby influences cellular motility and adhesion. It is also involved in activation of NADPH OXIDASE. This enzyme was formerly listed as EC 3.6.1.47.
| Descriptor ID |
D020830
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| MeSH Number(s) |
D08.811.277.040.330.300.400.700.100.500 D12.644.360.525.700.100.100 D12.776.157.325.515.700.100.100 D12.776.476.525.700.100.100
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| Concept/Terms |
rac1 GTP-Binding Protein- rac1 GTP-Binding Protein
- GTP-Binding Protein, rac1
- rac1 GTP Binding Protein
- ras-Related C3 Botulinum Toxin Substrate 1
- ras Related C3 Botulinum Toxin Substrate 1
- TC-25 GTP-Binding Protein
- GTP-Binding Protein, TC-25
- TC 25 GTP Binding Protein
- rac1 Protein
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Below are MeSH descriptors whose meaning is more general than "rac1 GTP-Binding Protein".
Below are MeSH descriptors whose meaning is more specific than "rac1 GTP-Binding Protein".
This graph shows the total number of publications written about "rac1 GTP-Binding Protein" by people in UAMS Profiles by year, and whether "rac1 GTP-Binding Protein" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 0 | 1 | 1 | | 2021 | 0 | 1 | 1 | | 2020 | 1 | 1 | 2 | | 2018 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 | | 2015 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2010 | 1 | 1 | 2 | | 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "rac1 GTP-Binding Protein" by people in Profiles over the past ten years.
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Chen YH, Hsu JY, Chu CT, Chang YW, Fan JR, Yang MH, Chen HC. Loss of cell-cell adhesion triggers cell migration through Rac1-dependent ROS generation. Life Sci Alliance. 2023 02; 6(2).
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Garitano-Trojaola A, Sancho A, G?tz R, Eiring P, Walz S, Jetani H, Gil-Pulido J, Da Via MC, Teufel E, Rhodes N, Haertle L, Arellano-Viera E, Tibes R, Rosenwald A, Rasche L, Hudecek M, Sauer M, Groll J, Einsele H, Kraus S, Kort?m MK. Actin cytoskeleton deregulation confers midostaurin resistance in FLT3-mutant acute myeloid leukemia. Commun Biol. 2021 06 25; 4(1):799.
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de Conti A, Tryndyak V, Heidor R, Jimenez L, Moreno FS, Beland FA, Rusyn I, Pogribny IP. Butyrate-containing structured lipids inhibit RAC1 and epithelial-to-mesenchymal transition markers: a chemopreventive mechanism against hepatocarcinogenesis. J Nutr Biochem. 2020 12; 86:108496.
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Newton J, Brown T, Corley C, Alexander T, Trujillo M, McElroy T, Ntagwabira F, Wang J, Byrum SD, Allen AR. Cranial irradiation impairs juvenile social memory and modulates hippocampal physiology. Brain Res. 2020 12 01; 1748:147095.
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Bright MD, Clarke PA, Workman P, Davies FE. Oncogenic RAC1 and NRAS drive resistance to endoplasmic reticulum stress through MEK/ERK signalling. Cell Signal. 2018 04; 44:127-137.
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Hassed S, Li S, Mulvihill J, Aston C, Palmer S. Adams-Oliver syndrome review of the literature: Refining the diagnostic phenotype. Am J Med Genet A. 2017 Mar; 173(3):790-800.
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Zhu M, Sun BH, Saar K, Simpson C, Troiano N, Dallas SL, Tiede-Lewis LM, Nevius E, Pereira JP, Weinstein RS, Tommasini SM, Insogna KL. Deletion of Rac in Mature Osteoclasts Causes Osteopetrosis, an Age-Dependent Change in Osteoclast Number, and a Reduced Number of Osteoblasts In Vivo. J Bone Miner Res. 2016 Apr; 31(4):864-73.
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