 Gene Targeting
"Gene Targeting" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The integration of exogenous DNA into the genome of an organism at sites where its expression can be suitably controlled. This integration occurs as a result of homologous recombination.
| Descriptor ID |
D018390
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| MeSH Number(s) |
E05.393.335
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| Concept/Terms |
Gene Targeting- Gene Targeting
- Gene Targetings
- Targeting, Gene
- Targetings, Gene
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Below are MeSH descriptors whose meaning is more general than "Gene Targeting".
Below are MeSH descriptors whose meaning is more specific than "Gene Targeting".
This graph shows the total number of publications written about "Gene Targeting" by people in UAMS Profiles by year, and whether "Gene Targeting" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 | | 2018 | 2 | 0 | 2 | | 2014 | 1 | 0 | 1 | | 2013 | 3 | 1 | 4 | | 2010 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2008 | 2 | 0 | 2 | | 2006 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 |
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Below are the most recent publications written about "Gene Targeting" by people in Profiles over the past ten years.
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Protacio RU, Wahls WP. Targeted Forward Genetics: Saturating Mutational Analyses of Specific Target Loci Within the Genome. Methods Mol Biol. 2025; 2862:223-239.
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Storey AJ, Wang HP, Protacio RU, Davidson MK, Wahls WP. Targeted Forward Genetics: Population-Scale Analyses of Allele Replacements Spanning Thousands of Base Pairs in Fission Yeast. G3 (Bethesda). 2019 12 03; 9(12):4097-4106.
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Iwata M, Englund DA, Wen Y, Dungan CM, Murach KA, Vechetti IJ, Mobley CB, Peterson CA, McCarthy JJ. A novel tetracycline-responsive transgenic mouse strain for skeletal muscle-specific gene expression. Skelet Muscle. 2018 10 27; 8(1):33.
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O'Brien CA, Morello R. Modeling Rare Bone Diseases in Animals. Curr Osteoporos Rep. 2018 08; 16(4):458-465.
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