An autosomal recessive disorder due to defects in PEROXISOME biogenesis which involves more than 13 genes encoding peroxin proteins of the peroxisomal membrane and matrix. Zellweger syndrome is typically seen in the neonatal period with features such as dysmorphic skull; MUSCLE HYPOTONIA; SENSORINEURAL HEARING LOSS; visual compromise; SEIZURES; progressive degeneration of the KIDNEYS and the LIVER. Zellweger-like syndrome refers to phenotypes resembling the neonatal Zellweger syndrome but seen in children or adults with apparently intact peroxisome biogenesis.

Descriptor ID	D015211
MeSH Number(s)	C06.552.970 C10.228.140.163.100.680.970 C12.777.419.978 C13.351.968.419.978 C16.131.077.970 C16.320.565.189.680.970 C16.320.565.663.970 C18.452.132.100.680.970 C18.452.648.189.680.970 C18.452.648.663.970
Concept/Terms	Zellweger Syndrome Zellweger Syndrome Cerebrohepatorenal Syndrome Cerebrohepatorenal Syndromes Zellweger's Syndrome Zellwegers Syndrome Cerebro-Hepato-Renal Syndrome Cerebro Hepato Renal Syndrome Cerebro-Hepato-Renal Syndromes Zellweger Disease Zellweger-Like Syndrome Zellweger-Like Syndrome Zellweger Like Syndrome

Below are MeSH descriptors whose meaning is more general than "Zellweger Syndrome".

Below are MeSH descriptors whose meaning is related to "Zellweger Syndrome".

Below are MeSH descriptors whose meaning is more specific than "Zellweger Syndrome".