 Ubiquitin-Activating Enzymes
"Ubiquitin-Activating Enzymes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of enzymes that catalyzes the ATP-dependent formation of a thioester bond between itself and UBIQUITIN. It then transfers the activated ubiquitin to one of the UBIQUITIN-PROTEIN LIGASES.
| Descriptor ID |
D044764
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| MeSH Number(s) |
D08.811.464.938.249
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| Concept/Terms |
Ubiquitin-Activating Enzymes- Ubiquitin-Activating Enzymes
- Enzymes, Ubiquitin-Activating
- Ubiquitin Activating Enzymes
- Ubiquitin-Activating Enzyme E1
- Enzyme E1, Ubiquitin-Activating
- Ubiquitin Activating Enzyme E1
- Ubiquitination Activating Enzyme E1
- Ubiquitin-Activating Enzyme
- Enzyme, Ubiquitin-Activating
- Ubiquitin Activating Enzyme
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Below are MeSH descriptors whose meaning is more general than "Ubiquitin-Activating Enzymes".
Below are MeSH descriptors whose meaning is more specific than "Ubiquitin-Activating Enzymes".
This graph shows the total number of publications written about "Ubiquitin-Activating Enzymes" by people in UAMS Profiles by year, and whether "Ubiquitin-Activating Enzymes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 1999 | 1 | 1 | 2 |
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Below are the most recent publications written about "Ubiquitin-Activating Enzymes" by people in Profiles over the past ten years.
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Chen X, Zhang Y, Ren X, Su Q, Liu Y, Dang X, Qin Y, Yang X, Xing Z, Shen Y, Wang Y, Bai Z, Yeh ETH, Wu H, Qi Y. The SUMO-specific protease SENP2 plays an essential role in the regulation of Kv7.2 and Kv7.3 potassium channels. J Biol Chem. 2021 10; 297(4):101183.
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Hyer ML, Milhollen MA, Ciavarri J, Fleming P, Traore T, Sappal D, Huck J, Shi J, Gavin J, Brownell J, Yang Y, Stringer B, Griffin R, Bruzzese F, Soucy T, Duffy J, Rabino C, Riceberg J, Hoar K, Lublinsky A, Menon S, Sintchak M, Bump N, Pulukuri SM, Langston S, Tirrell S, Kuranda M, Veiby P, Newcomb J, Li P, Wu JT, Powe J, Dick LR, Greenspan P, Galvin K, Manfredi M, Claiborne C, Amidon BS, Bence NF. A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment. Nat Med. 2018 02; 24(2):186-193.
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