 Nanoparticles
"Nanoparticles" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nanometer-sized particles that are nanoscale in three dimensions. They include nanocrystaline materials; NANOCAPSULES; METAL NANOPARTICLES; DENDRIMERS, and QUANTUM DOTS. The uses of nanoparticles include DRUG DELIVERY SYSTEMS and cancer targeting and imaging.
| Descriptor ID |
D053758
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| MeSH Number(s) |
J01.637.512.600
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| Concept/Terms |
Nanocrystalline Materials- Nanocrystalline Materials
- Material, Nanocrystalline
- Materials, Nanocrystalline
- Nanocrystalline Material
- Nanocrystals
- Nanocrystal
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Below are MeSH descriptors whose meaning is more general than "Nanoparticles".
Below are MeSH descriptors whose meaning is more specific than "Nanoparticles".
This graph shows the total number of publications written about "Nanoparticles" by people in UAMS Profiles by year, and whether "Nanoparticles" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2024 | 1 | 2 | 3 | | 2022 | 5 | 0 | 5 | | 2021 | 2 | 1 | 3 | | 2020 | 4 | 0 | 4 | | 2019 | 2 | 2 | 4 | | 2018 | 3 | 0 | 3 | | 2017 | 14 | 2 | 16 | | 2016 | 4 | 2 | 6 | | 2015 | 8 | 2 | 10 | | 2014 | 6 | 2 | 8 | | 2013 | 5 | 1 | 6 | | 2012 | 8 | 3 | 11 | | 2011 | 5 | 4 | 9 | | 2010 | 3 | 3 | 6 | | 2009 | 5 | 1 | 6 | | 2008 | 1 | 0 | 1 | | 2007 | 1 | 1 | 2 | | 2006 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Nanoparticles" by people in Profiles over the past ten years.
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Marwaha D, Singh N, Gautam S, Rai N, Tiwari P, Bakshi AK, Kumar A, Agarwal N, Sharma M, Shukla RP, Mishra PR. Pemetrexed-loaded supramolecular acetal-functionalized pH-responsive nanocarriers selectively induce apoptosis through biotin receptors to enhance antitumor efficacy. Colloids Surf B Biointerfaces. 2025 Jan; 245:114247.
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Ranch K, Chawnani D, Jani H, Acharya D, Patel CA, Jacob S, Babu RJ, Tiwari AK, Al-Tabakha MM, Boddu SHS. An update on the latest strategies in retinal drug delivery. Expert Opin Drug Deliv. 2024 May; 21(5):695-712.
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Khare S, Jog R, Bright A, Burgess DJ, Chakder SK, Gokulan K. Evaluation of mucosal immune profile associated with Zileuton nanocrystal-formulated BCS-II drug upon oral administration in Sprague Dawley rats. Nanotoxicology. 2023 Dec; 17(10):583-603.
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Adnan RM, Mezher M, Abdallah AM, Awad R, Khalil MI. Synthesis, Characterization, and Antibacterial Activity of Mg-Doped CuO Nanoparticles. Molecules. 2022 Dec 23; 28(1).
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Soltani-Kordshuli F, Choudhury D, Goss JA, Campbell M, Smith E, Sonntag S, Niyonshuti II, Okyere D, Smeltzer MS, Chen J, Zou M. Cartilage-inspired surface textures for improved tribological performance of orthopedic implants. J Mech Behav Biomed Mater. 2023 02; 138:105572.
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Li Y, Tiwari AK, Ng JS, Seah GL, Lim HK, Suteewong T, Tay CY, Lam YM, Tan KW. One-Pot Synthesis of Aminated Bimodal Mesoporous Silica Nanoparticles as Silver-Embedded Antibacterial Nanocarriers and CO2 Capture Sorbents. ACS Appl Mater Interfaces. 2022 Nov 23; 14(46):52279-52288.
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Ledezma DK, Balakrishnan PB, Shukla A, Medina JA, Chen J, Oakley E, Bollard CM, Shafirstein G, Miscuglio M, Fernandes R. Interstitial Photothermal Therapy Generates Durable Treatment Responses in Neuroblastoma. Adv Healthc Mater. 2022 10; 11(20):e2201084.
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Macchi S, Jalihal A, Hooshmand N, Zubair M, Jenkins S, Alwan N, El-Sayed M, Ali N, Griffin RJ, Siraj N. Enhanced photothermal heating and combination therapy of NIR dye via conversion to self-assembled ionic nanomaterials. J Mater Chem B. 2022 02 02; 10(5):806-816.
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Silva M, Kato Y, Melo MB, Phung I, Freeman BL, Li Z, Roh K, Van Wijnbergen JW, Watkins H, Enemuo CA, Hartwell BL, Chang JYH, Xiao S, Rodrigues KA, Cirelli KM, Li N, Haupt S, Aung A, Cossette B, Abraham W, Kataria S, Bastidas R, Bhiman J, Linde C, Bloom NI, Groschel B, Georgeson E, Phelps N, Thomas A, Bals J, Carnathan DG, Lingwood D, Burton DR, Alter G, Padera TP, Belcher AM, Schief WR, Silvestri G, Ruprecht RM, Crotty S, Irvine DJ. A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity. Sci Immunol. 2021 Dec 03; 6(66):eabf1152.
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Palliyage GH, Hussein N, Mimlitz M, Weeder C, Alnasser MHA, Singh S, Ekpenyong A, Tiwari AK, Chauhan H. Novel Curcumin-Resveratrol Solid Nanoparticles Synergistically Inhibit Proliferation of Melanoma Cells. Pharm Res. 2021 May; 38(5):851-871.
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Adkins D, Ley J, Atiq O, Powell S, Spanos WC, Gitau M, Rigden C, Palka K, Liu J, Oppelt P. Nanoparticle albumin-bound paclitaxel with cetuximab and carboplatin as first-line therapy for recurrent or metastatic head and neck cancer: A single-arm, multicenter, phase 2 trial. Oral Oncol. 2021 04; 115:105173.
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Cohen AA, Gnanapragasam PNP, Lee YE, Hoffman PR, Ou S, Kakutani LM, Keeffe JR, Wu HJ, Howarth M, West AP, Barnes CO, Nussenzweig MC, Bjorkman PJ. Mosaic nanoparticles elicit cross-reactive immune responses to zoonotic coronaviruses in mice. Science. 2021 02 12; 371(6530):735-741.
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Omyan G, Gholami S, Zad AG, Severgnini M, Longo F, Kalantari F. Monte Carlo simulation and analytical calculation methods to investigate the potential of nanoparticles for INTRABEAM? IORT machine. Nanomedicine. 2020 11; 30:102288.
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Newby SD, Masi T, Griffin CD, King WJ, Chipman A, Stephenson S, Anderson DE, Biris AS, Bourdo SE, Dhar M. Functionalized Graphene Nanoparticles Induce Human Mesenchymal Stem Cells to Express Distinct Extracellular Matrix Proteins Mediating Osteogenesis. Int J Nanomedicine. 2020; 15:2501-2513.
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Alam M, Zameer S, Najmi AK, Ahmad FJ, Imam SS, Akhtar M. Thymoquinone Loaded Solid Lipid Nanoparticles Demonstrated Antidepressant-Like Activity in Rats via Indoleamine 2, 3- Dioxygenase Pathway. Drug Res (Stuttg). 2020 May; 70(5):206-213.
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Darrigues E, Nima ZA, Nedosekin DA, Watanabe F, Alghazali KM, Zharov VP, Biris AS. Tracking Gold Nanorods' Interaction with Large 3D Pancreatic-Stromal Tumor Spheroids by Multimodal Imaging: Fluorescence, Photoacoustic, and Photothermal Microscopies. Sci Rep. 2020 02 25; 10(1):3362.
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Zhang L, Beatty A, Lu L, Abdalrahman A, Makris TM, Wang G, Wang Q. Microfluidic-assisted polymer-protein assembly to fabricate homogeneous functionalnanoparticles. Mater Sci Eng C Mater Biol Appl. 2020 Jun; 111:110768.
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Moyer TJ, Kato Y, Abraham W, Chang JYH, Kulp DW, Watson N, Turner HL, Menis S, Abbott RK, Bhiman JN, Melo MB, Simon HA, Herrera-De la Mata S, Liang S, Seumois G, Agarwal Y, Li N, Burton DR, Ward AB, Schief WR, Crotty S, Irvine DJ. Engineered immunogen binding to alum adjuvant enhances humoral immunity. Nat Med. 2020 03; 26(3):430-440.
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Heenatigala Palliyage G, Singh S, Ashby CR, Tiwari AK, Chauhan H. Pharmaceutical Topical Delivery of Poorly Soluble Polyphenols: Potential Role in Prevention and Treatment of Melanoma. AAPS PharmSciTech. 2019 Jul 11; 20(6):250.
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Zhang Q, Higginbotham JN, Jeppesen DK, Yang YP, Li W, McKinley ET, Graves-Deal R, Ping J, Britain CM, Dorsett KA, Hartman CL, Ford DA, Allen RM, Vickers KC, Liu Q, Franklin JL, Bellis SL, Coffey RJ. Transfer of Functional Cargo in Exomeres. Cell Rep. 2019 04 16; 27(3):940-954.e6.
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Gumireddy A, Christman R, Kumari D, Tiwari A, North EJ, Chauhan H. Preparation, Characterization, and In vitro Evaluation of Curcumin- and Resveratrol-Loaded Solid Lipid Nanoparticles. AAPS PharmSciTech. 2019 Mar 18; 20(4):145.
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Nima ZA, Watanabe F, Jamshidi-Parsian A, Sarimollaoglu M, Nedosekin DA, Han M, Watts JA, Biris AS, Zharov VP, Galanzha EI. Bioinspired magnetic nanoparticles as multimodal photoacoustic, photothermal and photomechanical contrast agents. Sci Rep. 2019 01 29; 9(1):887.
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Tokatlian T, Read BJ, Jones CA, Kulp DW, Menis S, Chang JYH, Steichen JM, Kumari S, Allen JD, Dane EL, Liguori A, Sangesland M, Lingwood D, Crispin M, Schief WR, Irvine DJ. Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers. Science. 2019 02 08; 363(6427):649-654.
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Taghizadehghalehjoughi A, Hacimuftuoglu A, Cetin M, Ugur AB, Galateanu B, Mezhuev Y, Okkay U, Taspinar N, Taspinar M, Uyanik A, Gundogdu B, Mohammadzadeh M, Nalci KA, Stivaktakis P, Tsatsakis A, Jung TW, Jeong JH, Abd El-Aty AM. Effect of metformin/irinotecan-loaded poly-lactic-co-glycolic acid nanoparticles on glioblastoma: in vitro and in vivo studies. Nanomedicine (Lond). 2018 07; 13(13):1595-1606.
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Meeker DG, Wang T, Harrington WN, Zharov VP, Johnson SA, Jenkins SV, Oyibo SE, Walker CM, Mills WB, Shirtliff ME, Beenken KE, Chen J, Smeltzer MS. Versatility of targeted antibiotic-loaded gold nanoconstructs for the treatment of biofilm-associated bacterial infections. Int J Hyperthermia. 2018 03; 34(2):209-219.
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Khan MA, Zafaryab M, Mehdi SH, Ahmad I, Rizvi MMA. Physicochemical Characterization of Curcumin Loaded Chitosan Nanoparticles: Implications in Cervical Cancer. Anticancer Agents Med Chem. 2018; 18(8):1131-1137.
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Qi R, Wang Y, Bruno PM, Xiao H, Yu Y, Li T, Lauffer S, Wei W, Chen Q, Kang X, Song H, Yang X, Huang X, Detappe A, Matulonis U, Pepin D, Hemann MT, Birrer MJ, Ghoroghchian PP. Nanoparticle conjugates of a highly potent toxin enhance safety and circumvent platinum resistance in ovarian cancer. Nat Commun. 2017 12 18; 8(1):2166.
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Shakeel K, Raisuddin S, Ali S, Imam SS, Rahman MA, Jain GK, Ahmad FJ. Development and in vitro/in vivo evaluation of artemether and lumefantrine co-loaded nanoliposomes for parenteral delivery. J Liposome Res. 2019 Mar; 29(1):35-43.
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Noh K, Mangala LS, Han HD, Zhang N, Pradeep S, Wu SY, Ma S, Mora E, Rupaimoole R, Jiang D, Wen Y, Shahzad MMK, Lyons Y, Cho M, Hu W, Nagaraja AS, Haemmerle M, Mak CSL, Chen X, Gharpure KM, Deng H, Xiong W, Kingsley CV, Liu J, Jennings N, Birrer MJ, Bouchard RR, Lopez-Berestein G, Coleman RL, An Z, Sood AK. Differential Effects of EGFL6 on Tumor versus Wound Angiogenesis. Cell Rep. 2017 Dec 05; 21(10):2785-2795.
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Koonce NA, Juratli MA, Cai C, Sarimollaoglu M, Menyaev YA, Dent J, Quick CM, Dings RPM, Nedosekin D, Zharov V, Griffin RJ. Real-time monitoring of circulating tumor cell (CTC) release after nanodrug or tumor radiotherapy using in?vivo flow cytometry. Biochem Biophys Res Commun. 2017 10 21; 492(3):507-512.
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Buchanan R. Introduction to graphene special edition. J Appl Toxicol. 2017 11; 37(11):1286-1287.
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Bourdo SE, Al Faouri R, Sleezer R, Nima ZA, Lafont A, Chhetri BP, Benamara M, Martin B, Salamo GJ, Biris AS. Physicochemical characteristics of pristine and functionalized graphene. J Appl Toxicol. 2017 Nov; 37(11):1288-1296.
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Darrigues E, Dantuluri V, Nima ZA, Vang-Dings KB, Griffin RJ, Biris AR, Ghosh A, Biris AS. Raman spectroscopy using plasmonic and carbon-based nanoparticles for cancer detection, diagnosis, and treatment guidance. Part 2: Treatment. Drug Metab Rev. 2017 05; 49(2):253-283.
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Darrigues E, Nima ZA, Majeed W, Vang-Dings KB, Dantuluri V, Biris AR, Zharov VP, Griffin RJ, Biris AS. Raman spectroscopy using plasmonic and carbon-based nanoparticles for cancer detection, diagnosis, and treatment guidance.Part 1: Diagnosis. Drug Metab Rev. 2017 05; 49(2):212-252.
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Elkhenany H, Bourdo S, Hecht S, Donnell R, Gerard D, Abdelwahed R, Lafont A, Alghazali K, Watanabe F, Biris AS, Anderson D, Dhar M. Graphene nanoparticles as osteoinductive and osteoconductive platform for stem cell and bone regeneration. Nanomedicine. 2017 Oct; 13(7):2117-2126.
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Fahmi T, Branch D, Nima ZA, Jang DS, Savenka AV, Biris AS, Basnakian AG. Mechanism of graphene-induced cytotoxicity: Role of endonucleases. J Appl Toxicol. 2017 Nov; 37(11):1325-1332.
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Nedosekin DA, Nolan J, Cai C, Bourdo SE, Nima Z, Biris AS, Zharov VP. In vivo noninvasive analysis of graphene nanomaterial pharmacokinetics using photoacoustic flow cytometry. J Appl Toxicol. 2017 Nov; 37(11):1297-1304.
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Al Faouri R, Henry R, Biris AS, Sleezer R, Salamo GJ. Adhesive force between graphene nanoscale flakes and living biological cells. J Appl Toxicol. 2017 Nov; 37(11):1346-1353.
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Lahiani MH, Gokulan K, Williams K, Khodakovskaya MV, Khare S. Graphene and carbon nanotubes activate different cell surface receptors on macrophages before and after deactivation of endotoxins. J Appl Toxicol. 2017 Nov; 37(11):1305-1316.
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Tao Z, Dang X, Huang X, Muzumdar MD, Xu ES, Bardhan NM, Song H, Qi R, Yu Y, Li T, Wei W, Wyckoff J, Birrer MJ, Belcher AM, Ghoroghchian PP. Early tumor detection afforded by in?vivo imaging of near-infrared II fluorescence. Biomaterials. 2017 Jul; 134:202-215.
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Petibone DM, Mustafa T, Bourdo SE, Lafont A, Ding W, Karmakar A, Nima ZA, Watanabe F, Casciano D, Morris SM, Dobrovolsky VN, Biris AS. p53-competent cells and p53-deficient cells display different susceptibility to oxygen functionalized graphene cytotoxicity and genotoxicity. J Appl Toxicol. 2017 Nov; 37(11):1333-1345.
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Gopala Krishna P, Paduvarahalli Ananthaswamy P, Trivedi P, Chaturvedi V, Bhangi Mutta N, Sannaiah A, Erra A, Yadavalli T. Antitubercular activity of ZnO nanoparticles prepared by solution combustion synthesis using lemon juice as bio-fuel. Mater Sci Eng C Mater Biol Appl. 2017 Jun 01; 75:1026-1033.
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Khan MA, Zafaryab M, Mehdi SH, Quadri J, Rizvi MM. Characterization and carboplatin loaded chitosan nanoparticles for the chemotherapy against breast cancer in vitro studies. Int J Biol Macromol. 2017 Apr; 97:115-122.
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Khan MA, Zafaryab M, Mehdi SH, Ahmad I, Rizvi MM. Characterization and anti-proliferative activity of curcumin loaded chitosan nanoparticles in cervical cancer. Int J Biol Macromol. 2016 Dec; 93(Pt A):242-253.
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Zhou Z, Kennell C, Lee JY, Leung YK, Tarapore P. Calcium phosphate-polymer hybrid nanoparticles for enhanced triple negative breast cancer treatment via co-delivery of paclitaxel and miR-221/222 inhibitors. Nanomedicine. 2017 02; 13(2):403-410.
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Zhang X, Tang K, Wang H, Liu Y, Bao B, Fang Y, Zhang X, Lu W. Design, Synthesis, and Biological Evaluation of New Cathepsin B-Sensitive Camptothecin Nanoparticles Equipped with a Novel Multifuctional Linker. Bioconjug Chem. 2016 05 18; 27(5):1267-75.
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Charlton JR, Pearl VM, Denotti AR, Lee JB, Swaminathan S, Scindia YM, Charlton NP, Baldelomar EJ, Beeman SC, Bennett KM. Biocompatibility of ferritin-based nanoparticles as targeted MRI contrast agents. Nanomedicine. 2016 08; 12(6):1735-45.
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Galanzha EI, Viegas MG, Malinsky TI, Melerzanov AV, Juratli MA, Sarimollaoglu M, Nedosekin DA, Zharov VP. In vivo acoustic and photoacoustic focusing of circulating cells. Sci Rep. 2016 Mar 16; 6:21531.
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Bekele AZ, Gokulan K, Williams KM, Khare S. Dose and Size-Dependent Antiviral Effects of Silver Nanoparticles on Feline Calicivirus, a Human Norovirus Surrogate. Foodborne Pathog Dis. 2016 05; 13(5):239-44.
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Zong H, Sen S, Zhang G, Mu C, Albayati ZF, Gorenstein DG, Liu X, Ferrari M, Crooks PA, Roboz GJ, Shen H, Guzman ML. In vivo targeting of leukemia stem cells by directing parthenolide-loaded nanoparticles to the bone marrow niche. Leukemia. 2016 07; 30(7):1582-6.
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Lu X, Miousse IR, Pirela SV, Moore JK, Melnyk S, Koturbash I, Demokritou P. In vivo epigenetic effects induced by engineered nanomaterials: A case study of copper oxide and laser printer-emitted engineered nanoparticles. Nanotoxicology. 2016; 10(5):629-39.
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Sethi P, Jyoti A, Swindell EP, Chan R, Langner UW, Feddock JM, Nagarajan R, O'Halloran TV, Upreti M. 3D tumor tissue analogs and their orthotopic implants for understanding tumor-targeting of microenvironment-responsive nanosized chemotherapy and radiation. Nanomedicine. 2015 Nov; 11(8):2013-23.
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Koonce NA, Quick CM, Hardee ME, Jamshidi-Parsian A, Dent JA, Paciotti GF, Nedosekin D, Dings RP, Griffin RJ. Combination of Gold Nanoparticle-Conjugated Tumor Necrosis Factor-a and Radiation Therapy Results in a Synergistic Antitumor Response in Murine Carcinoma Models. Int J Radiat Oncol Biol Phys. 2015 Nov 01; 93(3):588-96.
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Nanaware-Kharade N, Thakkar S, Gonzalez GA, Peterson EC. A Nanotechnology-Based Platform for Extending the Pharmacokinetic and Binding Properties of Anti-methamphetamine Antibody Fragments. Sci Rep. 2015 Jul 10; 5:12060.
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Nedosekin DA, Foster S, Nima ZA, Biris AS, Galanzha EI, Zharov VP. Photothermal confocal multicolor microscopy of nanoparticles and nanodrugs in live cells. Drug Metab Rev. 2015 08; 47(3):346-55.
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Pirela SV, Miousse IR, Lu X, Castranova V, Thomas T, Qian Y, Bello D, Kobzik L, Koturbash I, Demokritou P. Effects of Laser Printer-Emitted Engineered Nanoparticles on Cytotoxicity, Chemokine Expression, Reactive Oxygen Species, DNA Methylation, and DNA Damage: A Comprehensive in Vitro Analysis in Human Small Airway Epithelial Cells, Macrophages, and Lymphoblasts. Environ Health Perspect. 2016 Feb; 124(2):210-9.
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Lu X, Miousse IR, Pirela SV, Melnyk S, Koturbash I, Demokritou P. Short-term exposure to engineered nanomaterials affects cellular epigenome. Nanotoxicology. 2016; 10(2):140-50.
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Williamson SK, Johnson GA, Maulhardt HA, Moore KM, McMeekin DS, Schulz TK, Reed GA, Roby KF, Mackay CB, Smith HJ, Weir SJ, Wick JA, Markman M, diZerega GS, Baltezor MJ, Espinosa J, Decedue CJ. A phase I study of intraperitoneal nanoparticulate paclitaxel (Nanotax?) in patients with peritoneal malignancies. Cancer Chemother Pharmacol. 2015 May; 75(5):1075-87.
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Zhou Z, Badkas A, Stevenson M, Lee JY, Leung YK. Herceptin conjugated PLGA-PHis-PEG pH sensitive nanoparticles for targeted and controlled drug delivery. Int J Pharm. 2015 Jun 20; 487(1-2):81-90.
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Rychahou P, Haque F, Shu Y, Zaytseva Y, Weiss HL, Lee EY, Mustain W, Valentino J, Guo P, Evers BM. Delivery of RNA nanoparticles into colorectal cancer metastases following systemic administration. ACS Nano. 2015 Feb 24; 9(2):1108-16.
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