 Hydroxyeicosatetraenoic Acids
"Hydroxyeicosatetraenoic Acids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Eicosatetraenoic acids substituted in any position by one or more hydroxy groups. They are important intermediates in a series of biosynthetic processes leading from arachidonic acid to a number of biologically active compounds such as prostaglandins, thromboxanes, and leukotrienes.
| Descriptor ID |
D006893
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| MeSH Number(s) |
D10.251.355.096.450 D10.251.355.255.100.300
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hydroxyeicosatetraenoic Acids".
Below are MeSH descriptors whose meaning is more specific than "Hydroxyeicosatetraenoic Acids".
This graph shows the total number of publications written about "Hydroxyeicosatetraenoic Acids" by people in UAMS Profiles by year, and whether "Hydroxyeicosatetraenoic Acids" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2020 | 1 | 0 | 1 | | 2018 | 2 | 0 | 2 | | 2015 | 1 | 1 | 2 | | 2014 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2011 | 0 | 4 | 4 | | 2010 | 2 | 0 | 2 | | 2007 | 1 | 1 | 2 | | 2004 | 2 | 1 | 3 | | 1999 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hydroxyeicosatetraenoic Acids" by people in Profiles over the past ten years.
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Gawrys O, Huskov? Z, Baranowska I, Walkowska A, Sadowski J, Kikerlov? S, Vanourkov? Z, Honetschl?gerov? Z, ?karoupkov? P, Cervenka L, Falck JR, Imig JD, Kompanowska-Jezierska E. Combined treatment with epoxyeicosatrienoic acid analog and 20-hydroxyeicosatetraenoic acid antagonist provides substantial hypotensive effect in spontaneously hypertensive rats. J Hypertens. 2020 09; 38(9):1802-1810.
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Sedl?kov? L, Kikerlov? S, Huskov? Z, Cervenkov? L, Ch?bov? VC, Zicha J, Falck JR, Imig JD, Kompanowska-Jezierska E, Sadowski J, Kr?tk? V, Cervenka L, Kopkan L. 20-Hydroxyeicosatetraenoic acid antagonist attenuates the development of malignant hypertension and reverses it once established: a study in Cyp1a1-Ren-2 transgenic rats. Biosci Rep. 2018 10 31; 38(5).
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Yeboah MM, Hye Khan MA, Chesnik MA, Skibba M, Kolb LL, Imig JD. Role of the cytochrome P-450/ epoxyeicosatrienoic acids pathway in the pathogenesis of renal dysfunction in cirrhosis. Nephrol Dial Transplant. 2018 08 01; 33(8):1333-1343.
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Al?nov? P, Huskov? Z, Kopkan L, Sporkov? A, J?chov? ?, Neck?r J, Imig JD, Klevstig M, Kol?r F, Rami Reddy N, Falck JR, Sadowski J, Nishiyama A, Kramer HJ, Melenovsk? V, Cervenkov? L, Kujal P, Vernerov? Z, Cervenka L. Orally active epoxyeicosatrienoic acid analog does not exhibit antihypertensive and reno- or cardioprotective actions in two-kidney, one-clip Goldblatt hypertensive rats. Vascul Pharmacol. 2015 Oct; 73:45-56.
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Muroya Y, Fan F, Regner KR, Falck JR, Garrett MR, Juncos LA, Roman RJ. Deficiency in the Formation of 20-Hydroxyeicosatetraenoic Acid Enhances Renal Ischemia-Reperfusion Injury. J Am Soc Nephrol. 2015 Oct; 26(10):2460-9.
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Gangadhariah MH, Luther JM, Garcia V, Paueksakon P, Zhang MZ, Hayward SW, Love HD, Falck JR, Manthati VL, Imig JD, Schwartzman ML, Zent R, Capdevila JH, Pozzi A. Hypertension is a major contributor to 20-hydroxyeicosatetraenoic acid-mediated kidney injury in diabetic nephropathy. J Am Soc Nephrol. 2015 Mar; 26(3):597-610.
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