 8,11,14-Eicosatrienoic Acid
"8,11,14-Eicosatrienoic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. It differs from arachidonic acid, 5,8,11,14-eicosatetraenoic acid, only at position 5.
| Descriptor ID |
D015126
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| MeSH Number(s) |
D10.251.355.255.207
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| Concept/Terms |
8,11,14-Eicosatrienoic Acid- 8,11,14-Eicosatrienoic Acid
- Dihomo-gamma-Linolenic Acid
- Acid, Dihomo-gamma-Linolenic
- Dihomo gamma Linolenic Acid
- Dihomogammalinolenic Acid
- Acid, Dihomogammalinolenic
- 8,11,14 Eicosatrienoic Acid
- DHLA
Homo-gamma Linolenic Acid- Homo-gamma Linolenic Acid
- Acid, Homo-gamma Linolenic
- Homo gamma Linolenic Acid
- Linolenic Acid, Homo-gamma
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Below are MeSH descriptors whose meaning is more general than "8,11,14-Eicosatrienoic Acid".
Below are MeSH descriptors whose meaning is more specific than "8,11,14-Eicosatrienoic Acid".
This graph shows the total number of publications written about "8,11,14-Eicosatrienoic Acid" by people in UAMS Profiles by year, and whether "8,11,14-Eicosatrienoic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2016 | 2 | 0 | 2 | | 2015 | 1 | 1 | 2 | | 2014 | 1 | 1 | 2 | | 2013 | 2 | 0 | 2 | | 2012 | 1 | 0 | 1 | | 2011 | 1 | 1 | 2 | | 2010 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2006 | 2 | 0 | 2 |
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Below are the most recent publications written about "8,11,14-Eicosatrienoic Acid" by people in Profiles over the past ten years.
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Imig JD, Hye Khan MA, Burkhan A, Chen G, Adebesin AM, Falck JR. Kidney-Targeted Epoxyeicosatrienoic Acid Analog, EET-F01, Reduces Inflammation, Oxidative Stress, and Cisplatin-Induced Nephrotoxicity. Int J Mol Sci. 2021 Mar 10; 22(6).
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Imig JD, Jankiewicz WK, Khan AH. Epoxy Fatty Acids: From Salt Regulation to Kidney and Cardiovascular Therapeutics: 2019 Lewis K. Dahl Memorial Lecture. Hypertension. 2020 07; 76(1):3-15.
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Neck?r J, Hsu A, Hye Khan MA, Gross GJ, Nithipatikom K, Cyprov? M, Ben?k D, Hlav?ckov? M, Sot?kov?-Ka?parov? D, Falck JR, Sedmera D, Kol?r F, Imig JD. Infarct size-limiting effect of epoxyeicosatrienoic acid analog EET-B is mediated by hypoxia-inducible factor-1a via downregulation of prolyl hydroxylase 3. Am J Physiol Heart Circ Physiol. 2018 11 01; 315(5):H1148-H1158.
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Campbell WB, Imig JD, Schmitz JM, Falck JR. Orally Active Epoxyeicosatrienoic Acid Analogs. J Cardiovasc Pharmacol. 2017 Oct; 70(4):211-224.
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J?chov? ?, Kopkan L, Huskov? Z, Dole?elov? ?, Neck?r J, Kujal P, Vernerov? Z, Kramer HJ, Sadowski J, Kompanowska-Jezierska E, Reddy RN, Falck JR, Imig JD, Cervenka L. Epoxyeicosatrienoic acid analog attenuates the development of malignant hypertension, but does not reverse it once established: a study in Cyp1a1-Ren-2 transgenic rats. J Hypertens. 2016 10; 34(10):2008-25.
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Sporkov? A, Reddy RN, Falck JR, Imig JD, Kopkan L, Sadowski J, Cervenka L. Interlobular Arteries From 2-Kidney, 1-Clip Goldblatt Hypertensive Rats' Exhibit-Impaired Vasodilator Response to Epoxyeicosatrienoic Acids. Am J Med Sci. 2016 05; 351(5):513-9.
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Al?nov? P, Huskov? Z, Kopkan L, Sporkov? A, J?chov? ?, Neck?r J, Imig JD, Klevstig M, Kol?r F, Rami Reddy N, Falck JR, Sadowski J, Nishiyama A, Kramer HJ, Melenovsk? V, Cervenkov? L, Kujal P, Vernerov? Z, Cervenka L. Orally active epoxyeicosatrienoic acid analog does not exhibit antihypertensive and reno- or cardioprotective actions in two-kidney, one-clip Goldblatt hypertensive rats. Vascul Pharmacol. 2015 Oct; 73:45-56.
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Imig JD. Epoxyeicosatrienoic acids, hypertension, and kidney injury. Hypertension. 2015 Mar; 65(3):476-82.
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Hye Khan MA, Pavlov TS, Christain SV, Neck?r J, Staruschenko A, Gauthier KM, Capdevila JH, Falck JR, Campbell WB, Imig JD. Epoxyeicosatrienoic acid analogue lowers blood pressure through vasodilation and sodium channel inhibition. Clin Sci (Lond). 2014 Oct; 127(7):463-74.
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Falck JR, Koduru SR, Mohapatra S, Manne R, Atcha KR, Atcha R, Manthati VL, Capdevila JH, Christian S, Imig JD, Campbell WB. 14,15-Epoxyeicosa-5,8,11-trienoic Acid (14,15-EET) surrogates: carboxylate modifications. J Med Chem. 2014 Aug 28; 57(16):6965-72.
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