 Lactones
"Lactones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cyclic esters of hydroxy carboxylic acids, containing a 1-oxacycloalkan-2-one structure. Large cyclic lactones of over a dozen atoms are MACROLIDES.
| Descriptor ID |
D007783
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| MeSH Number(s) |
D02.540
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lactones".
Below are MeSH descriptors whose meaning is more specific than "Lactones".
This graph shows the total number of publications written about "Lactones" by people in UAMS Profiles by year, and whether "Lactones" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 0 | 1 | 1 | | 2020 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2009 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2006 | 0 | 2 | 2 | | 2004 | 3 | 0 | 3 | | 2003 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lactones" by people in Profiles over the past ten years.
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Penthala NR, Balasubramaniam M, Dachavaram SS, Morris EJ, Bhat-Nakshatri P, Ponder J, Jordan CT, Nakshatri H, Crooks PA. Antitumor properties of novel sesquiterpene lactone analogs as NF?B inhibitors that bind to the IKK? ubiquitin-like domain (ULD). Eur J Med Chem. 2021 Nov 15; 224:113675.
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Ord??ez PE, Mery DE, Sharma KK, Nemu S, Reynolds WF, Enriquez RG, Burns DC, Malag?n O, Jones DE, Guzman ML, Compadre CM. Synthesis, Crystallography, and Anti-Leukemic Activity of the Amino Adducts of Dehydroleucodine. Molecules. 2020 Oct 20; 25(20).
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Badros A, Singh Z, Dhakal B, Kwok Y, MacLaren A, Richardson P, Trikha M, Hari P. Marizomib for central nervous system-multiple myeloma. Br J Haematol. 2017 04; 177(2):221-225.
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Ord??ez PE, Sharma KK, Bystrom LM, Alas MA, Enriquez RG, Malag?n O, Jones DE, Guzman ML, Compadre CM. Dehydroleucodine, a Sesquiterpene Lactone from Gynoxys verrucosa, Demonstrates Cytotoxic Activity against Human Leukemia Cells. J Nat Prod. 2016 Apr 22; 79(4):691-6.
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