 Insulin-Like Growth Factor Binding Protein 1
"Insulin-Like Growth Factor Binding Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the six homologous proteins that specifically bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions. The function of this protein is not completely defined. However, several studies demonstrate that it inhibits IGF binding to cell surface receptors and thereby inhibits IGF-mediated mitogenic and cell metabolic actions. (Proc Soc Exp Biol Med 1993;204(1):4-29)
| Descriptor ID |
D018970
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| MeSH Number(s) |
D12.776.157.420.250
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Insulin-Like Growth Factor Binding Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Insulin-Like Growth Factor Binding Protein 1".
This graph shows the total number of publications written about "Insulin-Like Growth Factor Binding Protein 1" by people in UAMS Profiles by year, and whether "Insulin-Like Growth Factor Binding Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2025 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 | | 2005 | 1 | 0 | 1 | | 1998 | 0 | 1 | 1 |
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Below are the most recent publications written about "Insulin-Like Growth Factor Binding Protein 1" by people in Profiles over the past ten years.
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Holthoff JH, Karakala N, Basnakian AG, Edmondson RD, Fite TW, Gokden N, Harville Y, Herzog C, Holthoff KG, Juncos LA, Reynolds KL, Shelton RS, Arthur JM. The role of IGFBP-1 in the clinical prognosis and pathophysiology of acute kidney injury. Am J Physiol Renal Physiol. 2025 May 01; 328(5):F647-F661.
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Thakali KM, Faske JB, Ishwar A, Alfaro MP, Cleves MA, Badger TM, Andres A, Shankar K. Maternal obesity and gestational weight gain are modestly associated with umbilical cord DNA methylation. Placenta. 2017 Sep; 57:194-203.
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