 Joseph Holthoff
| Title | Assistant Professor |
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| Institution | University of Arkansas for Medical Sciences |
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| Department | Internal Med, College of Medicine |
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| Division | Internal Med Nephrology |
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| Address | B2-129-2 Biomedical Research I
324 UAMS Campus Dr.
Mail Slot # 501
Little Rock AR 72205
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| Phone | 501-686-5162 |
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| vCard | Download vCard |
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 Research 5R01DK126452 (HOLTHOFF, JOSEPH H)Feb 2, 2023 - May 31, 2026 NIH/Nat. Inst. of Diabetes & Digestive & Kidney Diseases
Endothelial Epoxygenase, Kidney Injury, and Blood Pressure Regulation
Role: Principal Investigator |
| 5R01DK126452-04 (HOLTHOFF, JOSEPH H)Feb 2, 2023 - May 31, 2026 NIH/Nat. Inst. of Diabetes & Digestive & Kidney Diseases
Endothelial Epoxygenase, Kidney Injury, and Blood Pressure Regulation
Role: Principal Investigator |
| 5R01DK126452-05 (HOLTHOFF, JOSEPH H)Feb 2, 2023 - May 31, 2026 NIH/Nat. Inst. of Diabetes & Digestive & Kidney Diseases
Endothelial Epoxygenase, Kidney Injury, and Blood Pressure Regulation
Role: Principal Investigator |
| 5R01DK126452-06 (HOLTHOFF, JOSEPH H)Feb 2, 2023 - May 31, 2026 NIH/Nat. Inst. of Diabetes & Digestive & Kidney Diseases
Endothelial Epoxygenase, Kidney Injury, and Blood Pressure Regulation
Role: Principal Investigator |
| 7R01DK126452 (HOLTHOFF, JOSEPH H)Feb 2, 2023 - May 31, 2026 NIH/Nat. Inst. of Diabetes & Digestive & Kidney Diseases
Endothelial Epoxygenase, Kidney Injury, and Blood Pressure Regulation
Role: Principal Investigator |
| 7R01DK126452-03 (HOLTHOFF, JOSEPH H)Feb 2, 2023 - May 31, 2026 NIH/Nat. Inst. of Diabetes & Digestive & Kidney Diseases
Endothelial Epoxygenase, Kidney Injury, and Blood Pressure Regulation
Role: Principal Investigator |
| C (HOLTHOFF, JOSEPH H)Dec 1, 2022 - Dec 30, 2024 Dialysis Clinic, Inc.
Investigating the mechanism of protection of IGFBP-1 in a murine model of acute kidney injury
Role: Principal Investigator |
| C-4208 (HOLTHOFF, JOSEPH H)Dec 1, 2022 - Dec 30, 2024 Dialysis Clinic, Inc.
Investigating the mechanism of protection of IGFBP-1 in a murine model of acute kidney injury
Role: Principal Investigator |
| F30DK085705 (HOLTHOFF, JOSEPH HUNTER)Apr 1, 2010 - Dec 31, 2014 NIH
Preclinical evaluation of resveratrol in sepsis-induced renal injury
Role: Principal Investigator |
Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Holthoff JH, Harville Y, Herzog C, Juncos LA, Karakala N, Arthur JM. SOD1 is a novel prognostic biomarker of acute kidney injury following cardiothoracic surgery. BMC Nephrol. 2023 10 11; 24(1):299. PMID: 37821813.
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Holthoff JH, Chandrashekar K, Juncos LA. The Role of Esm-1 in Diabetic Kidney Disease: More Than Just a Biomarker. Kidney360. 2022 Dec 29; 3(12):1998-2000. PMID: 36591366.
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Holthoff JH, Wang Z, Patil NK, Gokden N, Mayeux PR. Rolipram improves renal perfusion and function during sepsis in the mouse. J Pharmacol Exp Ther. 2013 Nov; 347(2):357-64. PMID: 24018639.
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Wang Z, Holthoff JH, Seely KA, Pathak E, Spencer HJ, Gokden N, Mayeux PR. Development of oxidative stress in the peritubular capillary microenvironment mediates sepsis-induced renal microcirculatory failure and acute kidney injury. Am J Pathol. 2012 Feb; 180(2):505-16. PMID: 22119717.
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Holthoff JH, Wang Z, Seely KA, Gokden N, Mayeux PR. Resveratrol improves renal microcirculation, protects the tubular epithelium, and prolongs survival in a mouse model of sepsis-induced acute kidney injury. Kidney Int. 2012 Feb; 81(4):370-8. PMID: 21975863.
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Myers CN, Berner GB, Holthoff JH, Martinez-Fonts K, Harper JA, Alford S, Taylor MN, Duina AA. Mutant versions of the S. cerevisiae transcription elongation factor Spt16 define regions of Spt16 that functionally interact with histone H3. PLoS One. 2011; 6(6):e20847. PMID: 21673966.
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Seely KA, Holthoff JH, Burns ST, Wang Z, Thakali KM, Gokden N, Rhee SW, Mayeux PR. Hemodynamic changes in the kidney in a pediatric rat model of sepsis-induced acute kidney injury. Am J Physiol Renal Physiol. 2011 Jul; 301(1):F209-17. PMID: 21511700.
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Holthoff JH, Woodling KA, Doerge DR, Burns ST, Hinson JA, Mayeux PR. Resveratrol, a dietary polyphenolic phytoalexin, is a functional scavenger of peroxynitrite. Biochem Pharmacol. 2010 Oct 15; 80(8):1260-5. PMID: 20599800.
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Wu L, Tiwari MM, Messer KJ, Holthoff JH, Gokden N, Brock RW, Mayeux PR. Peritubular capillary dysfunction and renal tubular epithelial cell stress following lipopolysaccharide administration in mice. Am J Physiol Renal Physiol. 2007 Jan; 292(1):F261-8. PMID: 16926442.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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| Year | Publications |
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| 2006 | 1 | | 2010 | 1 | | 2011 | 4 | | 2013 | 1 | | 2022 | 1 | | 2023 | 1 |
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