Christian Herzog
Title | Assistant Professor |
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Institution | University of Arkansas for Medical Sciences |
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Department | Internal Med, College of Medicine |
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Division | Internal Med Nephrology |
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Address | Campus General 200 South Cedar Mail Slot # 501 Little Rock AR 72202
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Phone | 501-626-8254 |
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ORCID
| 0000-0001-6024-3491 |
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vCard | Download vCard |
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Affiliation CCTR Pilot Study grant: 1UL1RR029884
Title: Nidogen as a Biomarker in Early Detection of Acute Kidney Injury
IACUC at CAVHS American Society of Nephrology
Research 1R41DK138646-01A1 (HERZOG, CHRISTIAN)Aug 1, 2024 - Jul 31, 2025 NIH/Nat. Inst. of Diabetes & Digestive & Kidney Diseases - Pass Through: Nephsmart, LLC A Device for Detection of Acute Kidney Injury Role: Principal Investigator |
| 1R41DK130702 (HERZOG, CHRISTIAN)Jul 1, 2021 - Jun 30, 2022 NIH/National Institutes of Health - Pass Through: Arkana Laboratories Development of a Precision Medicine-Based Diagnostic Tool for Membranous Nephropathy Role: Principal Investigator |
| U01DK103225 (ARTHUR, JOHN M)Jul 1, 2017 - Jun 30, 2018 NIH/Nat. Inst. of Diabetes & Digestive & Kidney Diseases - Pass Through: University of Pennsylvania Pilot: Glomerular biomarkers of progression in IgA nephropathy Role: Co-Investigator |
| R01DK081690 (KAUSHAL, GUR PRASAD)Mar 1, 2010 - Aug 31, 2015 NIH Meprin A Metalloproteinase in Acute Kidney Injury Role: Co-Investigator |
Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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Arthur JM, Forrest JC, Boehme KW, Kennedy JL, Owens S, Herzog C, Liu J, Harville TO. Correction: Development of ACE2 autoantibodies after SARS-CoV-2 infection. PLoS One. 2024; 19(11):e0314426. PMID: 39565738.
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Holthoff JH, Harville Y, Herzog C, Juncos LA, Karakala N, Arthur JM. SOD1 is a novel prognostic biomarker of acute kidney injury following cardiothoracic surgery. BMC Nephrol. 2023 10 11; 24(1):299. PMID: 37821813.
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Caza TN, Storey AJ, Hassen SI, Herzog C, Edmondson RD, Arthur JM, Kenan DJ, Larsen CP. Discovery of seven novel putative antigens in membranous nephropathy and membranous lupus nephritis identified by mass spectrometry. Kidney Int. 2023 03; 103(3):593-606. PMID: 36638888.
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Arthur JM, Forrest JC, Boehme KW, Kennedy JL, Owens S, Herzog C, Liu J, Harville TO. Development of ACE2 autoantibodies after SARS-CoV-2 infection. PLoS One. 2021; 16(9):e0257016. PMID: 34478478.
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Caza TN, Hassen SI, Kenan DJ, Storey A, Arthur JM, Herzog C, Edmondson RD, Bourne TD, Beck LH, Larsen CP. Transforming Growth Factor Beta Receptor 3 (TGFBR3)-Associated Membranous Nephropathy. Kidney360. 2021 08 26; 2(8):1275-1286. PMID: 35369660.
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Al-Rabadi LF, Caza T, Trivin-Avillach C, Rodan AR, Andeen N, Hayashi N, Williams B, Revelo MP, Clayton F, Abraham J, Lin E, Liou W, Zou CJ, Ramkumar N, Cummins T, Wilkey DW, Kawalit I, Herzog C, Storey A, Edmondson R, Sjoberg R, Yang T, Chien J, Merchant M, Arthur J, Klein J, Larsen C, Beck LH. Serine Protease HTRA1 as a Novel Target Antigen in Primary Membranous Nephropathy. J Am Soc Nephrol. 2021 Jul; 32(7):1666-1681. PMID: 33952630.
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Caza TN, Hassen SI, Kuperman M, Sharma SG, Dvanajscak Z, Arthur J, Edmondson R, Storey A, Herzog C, Kenan DJ, Larsen CP. Neural cell adhesion molecule 1 is a novel autoantigen in membranous lupus nephritis. Kidney Int. 2021 07; 100(1):171-181. PMID: 33045259.
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Caza TN, Hassen SI, Dvanajscak Z, Kuperman M, Edmondson R, Herzog C, Storey A, Arthur J, Cossey LN, Sharma SG, Kenan DJ, Larsen CP. NELL1 is a target antigen in malignancy-associated membranous nephropathy. Kidney Int. 2021 04; 99(4):967-976. PMID: 32828756.
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Larsen CP, Sharma SG, Caza TN, Kenan DJ, Storey AJ, Edmondson RD, Herzog C, Arthur JM. Serum amyloid P deposition is a sensitive and specific feature of membranous-like glomerulopathy with masked IgG kappa deposits. Kidney Int. 2020 03; 97(3):602-608. PMID: 32001064.
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Herzog C, Haun RS, Kaushal GP. Role of meprin metalloproteinases in cytokine processing and inflammation. Cytokine. 2019 02; 114:18-25. PMID: 30580156.
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Herzog C, Haun RS, Shah SV, Kaushal GP. Proteolytic processing and inactivation of CCL2/MCP-1 by meprins. Biochem Biophys Rep. 2016 Dec; 8:146-150. PMID: 28955950.
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Herzog C, Marisiddaiah R, Haun RS, Kaushal GP. Basement membrane protein nidogen-1 is a target of meprin ? in cisplatin nephrotoxicity. Toxicol Lett. 2015 Jul 16; 236(2):110-6. PMID: 25957482.
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Herzog C, Haun RS, Ludwig A, Shah SV, Kaushal GP. ADAM10 is the major sheddase responsible for the release of membrane-associated meprin A. J Biol Chem. 2014 May 09; 289(19):13308-22. PMID: 24662289.
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Kaushal V, Herzog C, Haun RS, Kaushal GP. Caspase protocols in mice. Methods Mol Biol. 2014; 1133:141-54. PMID: 24567100.
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Kaushal GP, Haun RS, Herzog C, Shah SV. Meprin A metalloproteinase and its role in acute kidney injury. Am J Physiol Renal Physiol. 2013 May 01; 304(9):F1150-8. PMID: 23427141.
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Herzog C, Yang C, Holmes A, Kaushal GP. zVAD-fmk prevents cisplatin-induced cleavage of autophagy proteins but impairs autophagic flux and worsens renal function. Am J Physiol Renal Physiol. 2012 Oct 15; 303(8):F1239-50. PMID: 22896037.
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Wang Z, Herzog C, Kaushal GP, Gokden N, Mayeux PR. Actinonin, a meprin A inhibitor, protects the renal microcirculation during sepsis. Shock. 2011 Feb; 35(2):141-7. PMID: 20577148.
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Liu L, Yang C, Herzog C, Seth R, Kaushal GP. Proteasome inhibitors prevent cisplatin-induced mitochondrial release of apoptosis-inducing factor and markedly ameliorate cisplatin nephrotoxicity. Biochem Pharmacol. 2010 Jan 15; 79(2):137-46. PMID: 19699182.
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Herzog C, Haun RS, Kaushal V, Mayeux PR, Shah SV, Kaushal GP. Meprin A and meprin alpha generate biologically functional IL-1beta from pro-IL-1beta. Biochem Biophys Res Commun. 2009 Feb 20; 379(4):904-8. PMID: 19135030.
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Kaushal GP, Kaushal V, Herzog C, Yang C. Autophagy delays apoptosis in renal tubular epithelial cells in cisplatin cytotoxicity. Autophagy. 2008 Jul; 4(5):710-2. PMID: 18497570.
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Herzog C, Seth R, Shah SV, Kaushal GP. Role of meprin A in renal tubular epithelial cell injury. Kidney Int. 2007 May; 71(10):1009-18. PMID: 17377510.
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Herzog C, Kaushal GP, Haun RS. Generation of biologically active interleukin-1beta by meprin B. Cytokine. 2005 Sep 07; 31(5):394-403. PMID: 16095909.
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Pal A, Gu Y, Herzog C, Srivastava SK, Zimniak P, Ji X, Singh SV. Role of arginine 216 in catalytic activity of murine Alpha class glutathione transferases mGSTAl-1 and mGSTA2-2 toward carcinogenic diol epoxides of polycyclic aromatic hydrocarbons. Carcinogenesis. 2001 Aug; 22(8):1301-5. PMID: 11470762.
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Pal A, Desai DH, Amin S, Srivastava SK, Hu X, Herzog C, Zimniak P, Singh SV. Location of the epoxide function determines specificity of the allelic variants of human glutathione transferase Pi toward benzo[c]chrysene diol epoxide isomers. FEBS Lett. 2000 Dec 08; 486(2):163-6. PMID: 11113459.
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Ji X, Blaszczyk J, Xiao B, O'Donnell R, Hu X, Herzog C, Singh SV, Zimniak P. Structure and function of residue 104 and water molecules in the xenobiotic substrate-binding site in human glutathione S-transferase P1-1. Biochemistry. 1999 Aug 10; 38(32):10231-8. PMID: 10441116.
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Hu X, Herzog C, Zimniak P, Singh SV. Differential protection against benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced DNA damage in HepG2 cells stably transfected with allelic variants of pi class human glutathione S-transferase. Cancer Res. 1999 May 15; 59(10):2358-62. PMID: 10344744.
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Mat? MJ, Zamocky M, Nykyri LM, Herzog C, Alzari PM, Betzel C, Koller F, Fita I. Structure of catalase-A from Saccharomyces cerevisiae. J Mol Biol. 1999 Feb 12; 286(1):135-49. PMID: 9931255.
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Hu X, Xia H, Srivastava SK, Herzog C, Awasthi YC, Ji X, Zimniak P, Singh SV. Activity of four allelic forms of glutathione S-transferase hGSTP1-1 for diol epoxides of polycyclic aromatic hydrocarbons. Biochem Biophys Res Commun. 1997 Sep 18; 238(2):397-402. PMID: 9299520.
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Zamocky M, Herzog C, Nykyri LM, Koller F. Site-directed mutagenesis of the lower parts of the major substrate channel of yeast catalase A leads to highly increased peroxidatic activity. FEBS Lett. 1995 Jul 03; 367(3):241-5. PMID: 7607315.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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Year | Publications |
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1995 | 1 | 1997 | 1 | 1999 | 3 | 2000 | 1 | 2001 | 1 | 2005 | 1 | 2007 | 1 | 2008 | 1 | 2009 | 2 | 2011 | 1 | 2012 | 1 | 2013 | 1 | 2014 | 2 | 2015 | 1 | 2016 | 1 | 2018 | 1 | 2019 | 1 | 2020 | 2 | 2021 | 3 | 2023 | 2 | 2024 | 1 |
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