 Amyloid Precursor Protein Secretases
"Amyloid Precursor Protein Secretases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Endopeptidases that are specific for AMYLOID PROTEIN PRECURSOR. Three secretase subtypes referred to as alpha, beta, and gamma have been identified based upon the region of amyloid protein precursor they cleave.
| Descriptor ID |
D053829
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| MeSH Number(s) |
D08.811.277.656.300.032
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Amyloid Precursor Protein Secretases".
Below are MeSH descriptors whose meaning is more specific than "Amyloid Precursor Protein Secretases".
This graph shows the total number of publications written about "Amyloid Precursor Protein Secretases" by people in UAMS Profiles by year, and whether "Amyloid Precursor Protein Secretases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2023 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Amyloid Precursor Protein Secretases" by people in Profiles over the past ten years.
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Garc?a-Guerrero E, Rodr?guez-Lobato LG, Sierro-Mart?nez B, Danhof S, Bates S, Frenz S, Haertle L, G?tz R, Sauer M, Rasche L, Kort?m KM, P?rez-Sim?n JA, Einsele H, Hudecek M, Prommersberger SR. All-trans retinoic acid works synergistically with the ?-secretase inhibitor crenigacestat to augment BCMA on multiple myeloma and the efficacy of BCMA-CAR T cells. Haematologica. 2023 02 01; 108(2):568-580.
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Dungan CM, Valentino T, Vechetti IJ, Zdunek CJ, Murphy MP, Lin AL, McCarthy JJ, Peterson CA. Exercise-mediated alteration of hippocampal Dicer mRNA and miRNAs is associated with lower BACE1 gene expression and A?1-42 in female 3xTg-AD mice. J Neurophysiol. 2020 12 01; 124(6):1571-1577.
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Wang W, Moerman-Herzog AM, Slaton A, Barger SW. Presenilin 1 mutations influence processing and trafficking of the ApoE receptor apoER2. Neurobiol Aging. 2017 01; 49:145-153.
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