 Ikaros Transcription Factor
"Ikaros Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor that plays a role as a key regulator of HEMATOPOIESIS. Aberrant Ikaros expression has been associated with LYMPHOBLASTIC LEUKEMIA.
| Descriptor ID |
D051740
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| MeSH Number(s) |
D12.776.260.522.500 D12.776.930.375.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ikaros Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "Ikaros Transcription Factor".
This graph shows the total number of publications written about "Ikaros Transcription Factor" by people in UAMS Profiles by year, and whether "Ikaros Transcription Factor" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ikaros Transcription Factor" by people in Profiles over the past ten years.
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Li D, Yu X, Kottur J, Gong W, Zhang Z, Storey AJ, Tsai YH, Uryu H, Shen Y, Byrum SD, Edmondson RD, Mackintosh SG, Cai L, Liu Z, Aggarwal AK, Tackett AJ, Liu J, Jin J, Wang GG. Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic. Oncogene. 2022 06; 41(24):3328-3340.
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Barrio S, Munawar U, Zhu YX, Giesen N, Shi CX, Vi? MD, Sanchez R, Bruins L, Demler T, M?ller N, Haertle L, Garitano A, Steinbrunn T, Danhof S, Cuenca I, Barrio-Garcia C, Braggio E, Rosenwald A, Martinez-Lopez J, Rasche L, Raab MS, Stewart AK, Einsele H, St?hmer T, Kort?m KM. IKZF1/3 and CRL4CRBN E3 ubiquitin ligase mutations and resistance to immunomodulatory drugs in multiple myeloma. Haematologica. 2020 05; 105(5):e237-e241.
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Patil A, Manzano M, Gottwein E. CK1a and IRF4 are essential and independent effectors of immunomodulatory drugs in primary effusion lymphoma. Blood. 2018 08 09; 132(6):577-586.
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