A group of inherited metabolic disorders which have in common elevations of serum LYSINE levels. Enzyme deficiencies of alpha-aminoadipic semialdehyde dehydrogenase and the SACCHAROPINE DEHYDROGENASES have been associated with hyperlysinemia. Clinical manifestations include mental retardation, recurrent emesis, hypotonia, lethargy, diarrhea, and developmental delay. (From Menkes, Textbook of Child Neurology, 5th ed, p56)

Descriptor ID	D020167
MeSH Number(s)	C10.228.140.163.100.380 C16.320.565.100.544 C16.320.565.189.380 C18.452.132.100.380 C18.452.648.100.544 C18.452.648.189.380
Concept/Terms	Hyperlysinemias Hyperlysinemias Lysine:Alpha-Ketoglutarate Reductase Deficiency L-Lysine:Nad-Oxido-Reductase Deficiency Hyperlysinemia Hyperlysinemia, Familial Familial Hyperlysinemia Familial Hyperlysinemias Hyperlysinemias, Familial Saccharopine Dehydrogenase Deficiency Disease Saccharopine Dehydrogenase Deficiency Disease Deficiency Disease, Saccharopine Dehydrogenase Lysine Alpha-Ketoglutarate Reductase Deficiency Disease Lysine Alpha-Ketoglutarate Reductase Deficiency Disease Lysine Alpha Ketoglutarate Reductase Deficiency Disease Deficiency Disease, Lysine Alpha-Ketoglutarate Reductase Deficiency Disease, Lysine Alpha Ketoglutarate Reductase Alpha-Aminoadipic Semialdehyde Deficiency Disease Alpha-Aminoadipic Semialdehyde Deficiency Disease Alpha Aminoadipic Semialdehyde Deficiency Disease Deficiency Disease, Alpha-Aminoadipic Semialdehyde Deficiency Disease, Alpha Aminoadipic Semialdehyde Hyperlysinemia, Periodic Hyperlysinemia, Periodic Hyperlysinemias, Periodic Periodic Hyperlysinemia Periodic Hyperlysinemias Hyperlysinuria With Hyperammonemia

Below are MeSH descriptors whose meaning is more general than "Hyperlysinemias".

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Below are MeSH descriptors whose meaning is more specific than "Hyperlysinemias".