 Microtubules
"Microtubules" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Slender, cylindrical filaments found in the cytoskeleton of plant and animal cells. They are composed of the protein TUBULIN and are influenced by TUBULIN MODULATORS.
| Descriptor ID |
D008870
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| MeSH Number(s) |
A11.284.430.214.190.750.602
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Microtubules".
Below are MeSH descriptors whose meaning is more specific than "Microtubules".
This graph shows the total number of publications written about "Microtubules" by people in UAMS Profiles by year, and whether "Microtubules" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2023 | 0 | 2 | 2 | | 2022 | 0 | 1 | 1 | | 2018 | 2 | 1 | 3 | | 2016 | 1 | 1 | 2 | | 2015 | 2 | 0 | 2 | | 2013 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2011 | 0 | 3 | 3 | | 2010 | 1 | 0 | 1 | | 2008 | 2 | 0 | 2 | | 2006 | 1 | 0 | 1 | | 2005 | 0 | 2 | 2 | | 2004 | 0 | 2 | 2 | | 2002 | 1 | 1 | 2 | | 2000 | 1 | 1 | 2 | | 1996 | 0 | 1 | 1 | | 1995 | 0 | 1 | 1 | | 1994 | 1 | 0 | 1 | | 1991 | 0 | 1 | 1 |
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Below are the most recent publications written about "Microtubules" by people in Profiles over the past ten years.
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Rahi A, Chakraborty M, Agarwal S, Vosberg KM, Agarwal S, Wang AY, McKenney RJ, Varma D. The Ndc80-Cdt1-Ska1 complex is a central processive kinetochore-microtubule coupling unit. J Cell Biol. 2023 08 07; 222(8).
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Ganne A, Balasubramaniam M, Ayyadevara H, Kiaei L, Shmookler Reis RJ, Varughese KI, Kiaei M. In silico analysis of TUBA4A mutations in Amyotrophic Lateral Sclerosis to define mechanisms of microtubule disintegration. Sci Rep. 2023 02 06; 13(1):2096.
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Delgado M, Rainwater RR, Heflin B, Urbaniak A, Butler K, Davidson M, Protacio RM, Baldini G, Edwards A, Reed MR, Raney KD, Chambers TC. Primary acute lymphoblastic leukemia cells are susceptible to microtubule depolymerization in G1 and M phases through distinct cell death pathways. J Biol Chem. 2022 06; 298(6):101939.
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Delgado M, Urbaniak A, Chambers TC. Contrasting effects of microtubule destabilizers versus stabilizers on induction of death in G1 phase of the cell cycle. Biochem Pharmacol. 2019 04; 162:213-223.
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Delgado M, Chambers TC. Microtubules play an essential role in the survival of primary acute lymphoblastic leukemia cells advancing through G1 phase. Cell Cycle. 2018; 17(14):1784-1796.
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Ding X, Pervere LM, Bascom C, Bibeau JP, Khurana S, Butt AM, Orr RG, Flaherty PJ, Bezanilla M, Vidali L. Conditional genetic screen in Physcomitrella patens reveals a novel microtubule depolymerizing-end-tracking protein. PLoS Genet. 2018 05; 14(5):e1007221.
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Renshaw H, Vargas-Mu?iz JM, Juvvadi PR, Richards AD, Waitt G, Soderblom EJ, Moseley MA, Steinbach WJ. The tail domain of the Aspergillus fumigatus class V myosin MyoE orchestrates septal localization and hyphal growth. J Cell Sci. 2018 02 07; 131(3).
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Ho SM, Rao R, To S, Schoch E, Tarapore P. Bisphenol A and its analogues disrupt centrosome cycle and microtubule dynamics in prostate cancer. Endocr Relat Cancer. 2017 02; 24(2):83-96.
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Colonne PM, Winchell CG, Voth DE. Hijacking Host Cell Highways: Manipulation of the Host Actin Cytoskeleton by Obligate Intracellular Bacterial Pathogens. Front Cell Infect Microbiol. 2016; 6:107.
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Kothari A, Hittelman WN, Chambers TC. Cell Cycle-Dependent Mechanisms Underlie Vincristine-Induced Death of Primary Acute Lymphoblastic Leukemia Cells. Cancer Res. 2016 06 15; 76(12):3553-61.
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Wang R, Stone RL, Kaelber JT, Rochat RH, Nick AM, Vijayan KV, Afshar-Kharghan V, Schmid MF, Dong JF, Sood AK, Chiu W. Electron cryotomography reveals ultrastructure alterations in platelets from patients with ovarian cancer. Proc Natl Acad Sci U S A. 2015 Nov 17; 112(46):14266-71.
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Wei W, Birrer MJ. Spleen Tyrosine Kinase Confers Paclitaxel Resistance in Ovarian Cancer. Cancer Cell. 2015 Jul 13; 28(1):7-9.
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