 HCT116 Cells
"HCT116 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Human COLORECTAL CARCINOMA cell line.
| Descriptor ID |
D045325
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| MeSH Number(s) |
A11.251.210.190.380 A11.251.860.180.380
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| Concept/Terms |
HCT116 Cells- HCT116 Cells
- Cell, HCT116
- Cells, HCT116
- HCT116 Cell
- HCT-116 Cells
- Cell, HCT-116
- Cells, HCT-116
- HCT-116 Cell
- HCT 116 Cells
- Cell, HCT 116
- Cells, HCT 116
- HCT 116 Cell
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Below are MeSH descriptors whose meaning is more general than "HCT116 Cells".
Below are MeSH descriptors whose meaning is more specific than "HCT116 Cells".
This graph shows the total number of publications written about "HCT116 Cells" by people in UAMS Profiles by year, and whether "HCT116 Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2025 | 0 | 2 | 2 | | 2024 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 | | 2021 | 0 | 2 | 2 | | 2020 | 0 | 3 | 3 | | 2019 | 0 | 3 | 3 | | 2018 | 0 | 1 | 1 | | 2017 | 0 | 3 | 3 | | 2016 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2011 | 0 | 5 | 5 | | 2009 | 0 | 3 | 3 | | 2008 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "HCT116 Cells" by people in Profiles over the past ten years.
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Neupane R, Karthikeyan C, Piedra V, Pasternak M, Boddu SHS, Ashby CR, Babu RJ, Tiwari AK. Novel macropinocytosis inducers selectively modulate intracellular delivery of small and macromolecules in cancer cells. Int J Biol Macromol. 2025 Sep; 322(Pt 3):146366.
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Xu J, Zhong Y, Qin M, Zhang Y, Ma Y, Hu B, Fu Q, Sun Y, Cheng M, Liu Y, Li J. Discovery and Administration Optimization of Novel Selective CDK9 Inhibitor, 1-7a-B1, for Improved Pharmacokinetics and Antitumor Efficacy In Vivo. J Med Chem. 2025 Jun 12; 68(11):11586-11605.
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El Sala AA, Khawaja G, Khalil M, Salam SA. Rosemary essential oil potentiates the antitumour activity of 5-fluorouracil in human colorectal carcinoma cells. J Pharm Pharmacol. 2024 Jun 06; 76(6):691-700.
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Xiao H, Ye X, Vishwakarma V, Preet R, Dixon DA. CRC-derived exosomes containing the RNA binding protein HuR promote lung cell proliferation by stabilizing c-Myc mRNA. Cancer Biol Ther. 2022 12 31; 23(1):139-149.
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Fields CJ, Li L, Hiers NM, Li T, Sheng P, Huda T, Shan J, Gay L, Gu T, Bian J, Kilberg MS, Renne R, Xie M. Sequencing of Argonaute-bound microRNA/mRNA hybrids reveals regulation of the unfolded protein response by microRNA-320a. PLoS Genet. 2021 12; 17(12):e1009934.
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Neupane R, Malla S, Abou-Dahech MS, Balaji S, Kumari S, Waiker DK, Moorthy NSHN, Trivedi P, Ashby CR, Karthikeyan C, Tiwari AK. Antiproliferative Efficacy of N-(3-chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine, DW-8, in Colon Cancer Cells Is Mediated by Intrinsic Apoptosis. Molecules. 2021 Jul 22; 26(15).
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Petitjean O, Girardi E, Ngondo RP, Lupashin V, Pfeffer S. Genome-Wide CRISPR-Cas9 Screen Reveals the Importance of the Heparan Sulfate Pathway and the Conserved Oligomeric Golgi Complex for Synthetic Double-Stranded RNA Uptake and Sindbis Virus Infection. mSphere. 2020 11 11; 5(6).
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Das KC, Muniyappa H, Kundumani-Sridharan V, Subramani J. Thioredoxin Decreases Anthracycline Cardiotoxicity, But Sensitizes Cancer Cell Apoptosis. Cardiovasc Toxicol. 2021 02; 21(2):142-151.
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Xu J, Tan HB, Zhang YJ, Tang DY, Zhan F, Li HY, Chen ZZ, Xu ZG. Catalyst-Free One-Pot Synthesis of Densely Substituted Pyrazole-Pyrazines as Anti-Colorectal Cancer Agents. Sci Rep. 2020 06 09; 10(1):9281.
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Jaiswal AS, Williamson EA, Srinivasan G, Kong K, Lomelino CL, McKenna R, Walter C, Sung P, Narayan S, Hromas R. The splicing component ISY1 regulates APE1 in base excision repair. DNA Repair (Amst). 2020 02; 86:102769.
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Wohak LE, Monien B, Phillips DH, Arlt VM. Impact of p53 function on the sulfotransferase-mediated bioactivation of the alkylated polycyclic aromatic hydrocarbon 1-hydroxymethylpyrene in vitro. Environ Mol Mutagen. 2019 10; 60(8):752-758.
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New J, Subramaniam D, Ramalingam S, Enders J, Sayed AAA, Ponnurangam S, Standing D, Ramamoorthy P, O'Neil M, Dixon DA, Saha S, Umar S, Gunewardena S, Jensen RA, Thomas SM, Anant S. Pleotropic role of RNA binding protein CELF2 in autophagy induction. Mol Carcinog. 2019 08; 58(8):1400-1409.
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Short SP, Barrett CW, Stengel KR, Revetta FL, Choksi YA, Coburn LA, Lintel MK, McDonough EM, Washington MK, Wilson KT, Prokhortchouk E, Chen X, Hiebert SW, Reynolds AB, Williams CS. Kaiso is required for MTG16-dependent effects on colitis-associated carcinoma. Oncogene. 2019 06; 38(25):5091-5106.
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Wohak LE, Baranski AC, Krais AM, Schmeiser HH, Phillips DH, Arlt VM. The impact of p53 function on the metabolic activation of the carcinogenic air pollutant 3-nitrobenzanthrone and its metabolites 3-aminobenzanthrone and N-hydroxy-3-aminobenzanthrone in human cells. Mutagenesis. 2018 10 11; 33(4):311-321.
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Hamed ANE, Schmitz R, Bergermann A, Totzke F, Kubbutat M, M?ller WEG, Youssef DTA, Bishr MM, Kamel MS, Edrada-Ebel R, W?tjen W, Proksch P. Bioactive pyrrole alkaloids isolated from the Red Sea: marine sponge Stylissa carteri. Z Naturforsch C J Biosci. 2018 Apr 25; 73(5-6):199-210.
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Willis AJ, Indra R, Wohak LE, Sozeri O, Feser K, Mrizova I, Phillips DH, Stiborova M, Arlt VM. The impact of chemotherapeutic drugs on the CYP1A1-catalysed metabolism of the environmental carcinogen benzo[a]pyrene: Effects in human colorectal HCT116 TP53(+/+), TP53(+/-) and TP53(-/-) cells. Toxicology. 2018 04 01; 398-399:1-12.
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Phillips CM, Zatarain JR, Nicholls ME, Porter C, Widen SG, Thanki K, Johnson P, Jawad MU, Moyer MP, Randall JW, Hellmich JL, Maskey M, Qiu S, Wood TG, Druzhyna N, Szczesny B, M?dis K, Szabo C, Chao C, Hellmich MR. Upregulation of Cystathionine-?-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis. Cancer Res. 2017 11 01; 77(21):5741-5754.
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Brandt KE, Falls KC, Schoenfeld JD, Rodman SN, Gu Z, Zhan F, Cullen JJ, Wagner BA, Buettner GR, Allen BG, Berg DJ, Spitz DR, Fath MA. Augmentation of intracellular iron using iron sucrose enhances the toxicity of pharmacological ascorbate in colon cancer cells. Redox Biol. 2018 04; 14:82-87.
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Zeng H, Taussig DP, Cheng WH, Johnson LK, Hakkak R. Butyrate Inhibits Cancerous HCT116 Colon Cell Proliferation but to a Lesser Extent in Noncancerous NCM460 Colon Cells. Nutrients. 2017 Jan 01; 9(1).
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Blanco FF, Preet R, Aguado A, Vishwakarma V, Stevens LE, Vyas A, Padhye S, Xu L, Weir SJ, Anant S, Meisner-Kober N, Brody JR, Dixon DA. Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis. Oncotarget. 2016 Nov 08; 7(45):74043-74058.
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Tseng A, Yang CH, Chen CH, Chen CH, Hsu SL, Lee MH, Lee HC, Su LJ. An in vivo molecular response analysis of colorectal cancer treated with Astragalus membranaceus extract. Oncol Rep. 2016 Feb; 35(2):659-68.
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