 Hep G2 Cells
"Hep G2 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A human liver tumor cell line used to study a variety of liver-specific metabolic functions.
| Descriptor ID |
D056945
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| MeSH Number(s) |
A11.251.860.180.432 A11.436.348.500
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| Concept/Terms |
Hep G2 Cells- Hep G2 Cells
- Cell, Hep G2
- Cells, Hep G2
- Hep G2 Cell
- HepG2 Cells
- Cell, HepG2
- Cells, HepG2
- HepG2 Cell
- Hep G2 Cell Line
- Hepatoblastoma G2 Cell Line
- Cell Line, Hep G2
- Cell Line, Hepatoblastoma G2
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Below are MeSH descriptors whose meaning is more general than "Hep G2 Cells".
Below are MeSH descriptors whose meaning is more specific than "Hep G2 Cells".
This graph shows the total number of publications written about "Hep G2 Cells" by people in UAMS Profiles by year, and whether "Hep G2 Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 0 | 1 | 1 | | 2020 | 0 | 4 | 4 | | 2019 | 0 | 4 | 4 | | 2018 | 0 | 3 | 3 | | 2017 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2015 | 0 | 6 | 6 | | 2014 | 0 | 2 | 2 | | 2013 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2011 | 0 | 4 | 4 | | 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hep G2 Cells" by people in Profiles over the past ten years.
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Wang W, Li J, Tan J, Wang M, Yang J, Zhang ZM, Li C, Basnakian AG, Tang HW, Perrimon N, Zhou Q. Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response. Nat Commun. 2021 01 20; 12(1):476.
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Partridge EC, Chhetri SB, Prokop JW, Ramaker RC, Jansen CS, Goh ST, Mackiewicz M, Newberry KM, Brandsmeier LA, Meadows SK, Messer CL, Hardigan AA, Coppola CJ, Dean EC, Jiang S, Savic D, Mortazavi A, Wold BJ, Myers RM, Mendenhall EM. Occupancy maps of 208 chromatin-associated proteins in one human cell type. Nature. 2020 07; 583(7818):720-728.
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Ramaker RC, Hardigan AA, Goh ST, Partridge EC, Wold B, Cooper SJ, Myers RM. Dissecting the regulatory activity and sequence content of loci with exceptional numbers of transcription factor associations. Genome Res. 2020 07; 30(7):939-950.
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Elsawy H, Algefare AI, Alfwuaires M, Khalil M, Elmenshawy OM, Sedky A, Abdel-Moneim AM. Naringin alleviates methotrexate-induced liver injury in male albino rats and enhances its antitumor efficacy in HepG2 cells. Biosci Rep. 2020 06 26; 40(6).
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Reed L, Jarvis IWH, Phillips DH, Arlt VM. Enhanced DNA adduct formation by benzo[a]pyrene in human liver cells lacking cytochrome P450 oxidoreductase. Mutat Res Genet Toxicol Environ Mutagen. 2020 Apr; 852:503162.
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Hamida RS, Abdelmeguid NE, Ali MA, Bin-Meferij MM, Khalil MI. Synthesis of Silver Nanoparticles Using a Novel Cyanobacteria Desertifilum sp. extract: Their Antibacterial and Cytotoxicity Effects. Int J Nanomedicine. 2020; 15:49-63.
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Borowa-Mazgaj B, de Conti A, Tryndyak V, Steward CR, Jimenez L, Melnyk S, Seneshaw M, Mirshahi F, Rusyn I, Beland FA, Sanyal AJ, Pogribny IP. Gene Expression and DNA Methylation Alterations in the Glycine N-Methyltransferase Gene in Diet-Induced Nonalcoholic Fatty Liver Disease-Associated Carcinogenesis. Toxicol Sci. 2019 08 01; 170(2):273-282.
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Feng H, Bao S, Rahman MA, Weyn-Vanhentenryck SM, Khan A, Wong J, Shah A, Flynn ED, Krainer AR, Zhang C. Modeling RNA-Binding Protein Specificity In?Vivo by Precisely Registering Protein-RNA Crosslink Sites. Mol Cell. 2019 06 20; 74(6):1189-1204.e6.
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Khanal T, Leung YK, Jiang W, Timchenko N, Ho SM, Kim K. NR2E3 is a key component in p53 activation by regulating a long noncoding RNA DINO in acute liver injuries. FASEB J. 2019 07; 33(7):8335-8348.
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Seo JE, Tryndyak V, Wu Q, Dreval K, Pogribny I, Bryant M, Zhou T, Robison TW, Mei N, Guo X. Quantitative comparison of in vitro genotoxicity between metabolically competent HepaRG cells and HepG2 cells using the high-throughput high-content CometChip assay. Arch Toxicol. 2019 05; 93(5):1433-1448.
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Jamshidi-Parsian A, Griffin RJ, Kore RA, Todorova VK, Makhoul I. Tumor-endothelial cell interaction in an experimental model of human hepatocellular carcinoma. Exp Cell Res. 2018 11 01; 372(1):16-24.
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Bohanon FJ, Nunez Lopez O, Herndon DN, Wang X, Bhattarai N, Ayadi AE, Prasai A, Jay JW, Rojas-Khalil Y, Toliver-Kinsky TE, Finnerty CC, Radhakrishnan RS, Porter C. Burn Trauma Acutely Increases the Respiratory Capacity and Function of Liver Mitochondria. Shock. 2018 04; 49(4):466-473.
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Hejazi II, Khanam R, Mehdi SH, Bhat AR, Rizvi MMA, Thakur SC, Athar F. Antioxidative and anti-proliferative potential of Curculigo orchioides Gaertn in oxidative stress induced cytotoxicity: In vitro, ex vivo and in silico studies. Food Chem Toxicol. 2018 May; 115:244-259.
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Hejazi II, Khanam R, Mehdi SH, Bhat AR, Moshahid Alam Rizvi M, Islam A, Thakur SC, Athar F. New insights into the antioxidant and apoptotic potential of Glycyrrhiza glabra L. during hydrogen peroxide mediated oxidative stress: An in vitro and in silico evaluation. Biomed Pharmacother. 2017 Oct; 94:265-279.
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Jarret A, McFarland AP, Horner SM, Kell A, Schwerk J, Hong M, Badil S, Joslyn RC, Baker DP, Carrington M, Hagedorn CH, Gale M, Savan R. Hepatitis-C-virus-induced microRNAs dampen interferon-mediated antiviral signaling. Nat Med. 2016 Dec; 22(12):1475-1481.
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Asakura M, Karaki F, Fujii H, Atsuda K, Itoh T, Fujiwara R. Vildagliptin and its metabolite M20.7 induce the expression of S100A8 and S100A9 in human hepatoma HepG2 and leukemia HL-60 cells. Sci Rep. 2016 10 19; 6:35633.
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Yamashita Y, Asakura M, Mitsugi R, Fujii H, Nagai K, Atsuda K, Itoh T, Fujiwara R. MicroRNA expression in the vildagliptin-treated two- and three-dimensional HepG2 cells. Drug Metab Pharmacokinet. 2016 Jun; 31(3):201-9.
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Zhang Y, Liu C, Barbier O, Smalling R, Tsuchiya H, Lee S, Delker D, Zou A, Hagedorn CH, Wang L. Bcl2 is a critical regulator of bile acid homeostasis by dictating Shp and lncRNA H19 function. Sci Rep. 2016 Feb 03; 6:20559.
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Kindrat I, Tryndyak V, de Conti A, Shpyleva S, Mudalige TK, Kobets T, Erstenyuk AM, Beland FA, Pogribny IP. MicroRNA-152-mediated dysregulation of hepatic transferrin receptor 1 in liver carcinogenesis. Oncotarget. 2016 Jan 12; 7(2):1276-87.
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Mitsugi R, Sumida K, Fujie Y, Tukey RH, Itoh T, Fujiwara R. Acyl-glucuronide as a Possible Cause of Trovafloxacin-Induced Liver Toxicity: Induction of Chemokine (C-X-C Motif) Ligand 2 by Trovafloxacin Acyl-glucuronide. Biol Pharm Bull. 2016; 39(10):1604-1610.
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Hajirahimkhan A, Simmler C, Dong H, Lantvit DD, Li G, Chen SN, Nikolic D, Pauli GF, van Breemen RB, Dietz BM, Bolton JL. Induction of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) by Glycyrrhiza Species Used for Women's Health: Differential Effects of the Michael Acceptors Isoliquiritigenin and Licochalcone A. Chem Res Toxicol. 2015 Nov 16; 28(11):2130-41.
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Liem PH, Mu A, Kikuta S, Ohta K, Kitajima S, Taketani S. A simple and highly sensitive method of measuring heme oxygenase activity. Biol Chem. 2015 Nov; 396(11):1265-8.
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Khalil MI, Ibrahim MM, El-Gaaly GA, Sultan AS. Trigonella foenum (Fenugreek) Induced Apoptosis in Hepatocellular Carcinoma Cell Line, HepG2, Mediated by Upregulation of p53 and Proliferating Cell Nuclear Antigen. Biomed Res Int. 2015; 2015:914645.
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Yu D, Tolleson WH, Knox B, Jin Y, Guo L, Guo Y, Kadlubar SA, Ning B. Modulation of ALDH5A1 and SLC22A7 by microRNA hsa-miR-29a-3p in human liver cells. Biochem Pharmacol. 2015 Dec 15; 98(4):671-80.
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Woolbright BL, McGill MR, Yan H, Jaeschke H. Bile Acid-Induced Toxicity in HepaRG Cells Recapitulates the Response in Primary Human Hepatocytes. Basic Clin Pharmacol Toxicol. 2016 Feb; 118(2):160-7.
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Yu D, Green B, Marrone A, Guo Y, Kadlubar S, Lin D, Fuscoe J, Pogribny I, Ning B. Suppression of CYP2C9 by microRNA hsa-miR-128-3p in human liver cells and association with hepatocellular carcinoma. Sci Rep. 2015 Feb 23; 5:8534.
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Bogusiewicz A, Boysen G, Mock DM. In HepG2 cells, coexisting carnitine deficiency masks important indicators of marginal biotin deficiency. J Nutr. 2015 Jan; 145(1):32-40.
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