Cross-Over Studies
"Cross-Over Studies" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)
Descriptor ID |
D018592
|
MeSH Number(s) |
E05.318.780.150 N05.715.360.780.150 N06.850.520.445.150
|
Concept/Terms |
Cross-Over Studies- Cross-Over Studies
- Cross Over Studies
- Cross-Over Study
- Studies, Cross-Over
- Study, Cross-Over
- Crossover Studies
- Crossover Study
- Studies, Crossover
- Study, Crossover
- Cross-Over Trials
- Cross Over Trials
- Trial, Cross-Over
- Trials, Cross-Over
- Crossover Trials
- Trial, Crossover
- Trials, Crossover
Cross-Over Design- Cross-Over Design
- Cross Over Design
- Cross-Over Designs
- Design, Cross-Over
- Designs, Cross-Over
- Crossover Design
- Crossover Designs
- Design, Crossover
- Designs, Crossover
|
Below are MeSH descriptors whose meaning is more general than "Cross-Over Studies".
Below are MeSH descriptors whose meaning is more specific than "Cross-Over Studies".
This graph shows the total number of publications written about "Cross-Over Studies" by people in UAMS Profiles by year, and whether "Cross-Over Studies" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
---|
2025 | 0 | 4 | 4 | 2024 | 3 | 1 | 4 | 2023 | 0 | 1 | 1 | 2022 | 0 | 3 | 3 | 2021 | 0 | 2 | 2 | 2020 | 0 | 5 | 5 | 2019 | 0 | 6 | 6 | 2018 | 0 | 5 | 5 | 2017 | 0 | 8 | 8 | 2016 | 0 | 4 | 4 | 2015 | 0 | 3 | 3 | 2014 | 0 | 2 | 2 | 2013 | 0 | 1 | 1 | 2012 | 0 | 6 | 6 | 2011 | 0 | 5 | 5 | 2010 | 0 | 3 | 3 | 2009 | 0 | 2 | 2 | 2008 | 0 | 3 | 3 | 2007 | 0 | 3 | 3 | 2006 | 0 | 1 | 1 | 2005 | 0 | 5 | 5 | 2004 | 0 | 5 | 5 | 2003 | 0 | 4 | 4 | 2002 | 0 | 1 | 1 | 2001 | 0 | 2 | 2 | 2000 | 0 | 1 | 1 | 1999 | 0 | 7 | 7 | 1998 | 0 | 3 | 3 | 1996 | 0 | 1 | 1 | 1995 | 0 | 1 | 1 | 1994 | 0 | 2 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Cross-Over Studies" by people in Profiles over the past ten years.
-
Kirschner SK, Engelen MP, Haas P, Bischoff SC, Deutz NE. Short-chain fatty acid kinetics and concentrations are higher after inulin supplementation in young and older adults: a randomized trial. Am J Clin Nutr. 2025 Jun; 121(6):1224-1235.
-
Hill Z, McCarty PJ, Boles RG, Frye RE. A Mitochondrial Supplement Improves Function and Mitochondrial Activity in Autism: A Double-Blind Placebo-Controlled Cross-Over Trial. Int J Mol Sci. 2025 Mar 10; 26(6).
-
Nghiem PP, Rutledge AM, Tehas K, Kaderli C, Poling M, Arnim S, Dernov V, van Sas C, Mackey ML, Have GAMT, Engelen MPKJ, Deutz NEP. Beta-hydroxy-beta-methylbutyrate (HMB) improves daily activity and whole-body protein metabolism in Duchenne muscular dystrophy dogs: a pilot study. Sci Rep. 2025 Feb 02; 15(1):4026.
-
Porter A, Smith AM, Gokarakonda SB, Wilson MP, Martin BC. Empty bottles, rising risks: A case-crossover study on psychotherapeutic medication depletion and suicide triggers. J Affect Disord. 2025 Apr 01; 374:579-586.
-
Rose NR, Bailey J, Anderson JD, Chalamalla AR, Ryan KJ, Acosta EP, Guimbellot JS. Pilot and feasibility study of dietary composition with elexacaftor-tezacaftor-ivacaftor concentrations in people with cystic fibrosis. Pharmacotherapy. 2024 Dec; 44(12):920-926.
-
Smith AM, Peng C, Porter A, Martin BC. The role of prescribed controlled substance acquisition as potential triggers of opioid overdose: A case-crossover study. Int J Drug Policy. 2024 Dec; 134:104620.
-
Woodward A, Coleman E, Ronaldson S, Zoltie T, Bartlett P, Wilson L, Archer T, Kawalek J, Boele F, Chang B, Kalantzis G, Theaker M, El-Hindy N, Walshaw E, Gout T, Watson J. A cross-over, randomised feasibility study of digitally-printed versus hand-painted artificial eyes in adults: PERSONAL-EYE-S. Eye (Lond). 2024 Dec; 38(17):3263-3271.
-
Jebai R, Asfar T, Cano M?, Nakkash R, Schmidt M, Wu W, Bursac Z, Maziak W. Effects of Pictorial Health Warning Labels on Intention to Quit Waterpipe in Lebanon: A Mediation Analysis. Nicotine Tob Res. 2024 05 22; 26(6):764-770.
-
Lynch AL, Matlock DN, Akmyradov C, Weisner MD, Beck J, Sinderby C, Courtney SE. Tidal volume delivery during nasal intermittent positive pressure ventilation: infant cannula vs. nasal continuous positive airway pressure prongs. J Perinatol. 2024 02; 44(2):244-249.
-
Hodges JK, Maiz M, Cao S, Lachcik PJ, Peacock M, McCabe GP, McCabe LD, Cladis DP, Jackson GS, Ferruzzi MG, Lila MA, Bailey RL, Martin BR, Weaver CM. Moderate consumption of freeze-dried blueberry powder increased net bone calcium retention compared with no treatment in healthy postmenopausal women: a randomized crossover trial. Am J Clin Nutr. 2023 08; 118(2):382-390.
-
Chawla V. EBNEO commentary on "umbilical cord milking in nonvigorous infants: A cluster-randomised crossover trial". Acta Paediatr. 2023 02; 112(2):324-325.
-
Hirsch KR, Church DD, Wolfe RR, Ferrando AA. Continuous oral stable isotope ingestion to measure whole-body protein turnover. Clin Nutr ESPEN. 2022 06; 49:385-389.
-
Uyoga MA, Mzembe G, Stoffel NU, Moretti D, Zeder C, Phiri K, Sabatier M, Hays NP, Zimmermann MB, Mwangi MN. Iron Bioavailability from Infant Cereals Containing Whole Grains and Pulses: A Stable Isotope Study in Malawian Children. J Nutr. 2022 03 03; 152(3):826-834.
-
Coelho OGL, Alfenas RCG, Debelo H, Wightman JD, Ferruzzi MG, Mattes RD. Effects of Concord grape juice flavor intensity and phenolic compound content on glycemia, appetite and cognitive function in adults with excess body weight: a randomized double-blind crossover trial. Food Funct. 2021 Nov 15; 12(22):11469-11481.
-
Thompson AM, Fernandez JM, Shih T, Hamzavi I, Hsiao JL, Shi VY. Improving hidradenitis suppurativa patient education using written action plan: a randomized controlled trial. J Dermatolog Treat. 2022 Aug; 33(5):2677-2679.
-
Fishe J, Zheng Y, Lyu T, Bian J, Hu H. Environmental effects on acute exacerbations of respiratory diseases: A real-world big data study. Sci Total Environ. 2022 Feb 01; 806(Pt 1):150352.
-
Davis AM, Darden PM, Snowden J, Simon AE, McCulloh RJ, Bimali M, Lee J. Rationale and protocol for a cluster randomized, cross-over trial of recruitment methods of rural children in primary care clinics: A feasibility study of a pediatric weight control trial in the IDeA States Pediatric Clinical Trials Network. Contemp Clin Trials. 2021 08; 107:106476.
-
Suh H, Lieberman HR, Jansen LT, Colburn AT, Adams JD, Seal AD, Butts CL, Kirkland TM, Melander O, Vanhaecke T, Dolci A, Lemetais G, Perrier ET, Kavouras SA. Cellular dehydration acutely degrades mood mainly in women: a counterbalanced, crossover trial. Br J Nutr. 2021 05 28; 125(10):1092-1100.
-
Gu C, Brereton N, Schweitzer A, Cotter M, Duan D, B?rsheim E, Wolfe RR, Pham LV, Polotsky VY, Jun JC. Metabolic Effects of Late Dinner in Healthy Volunteers-A Randomized Crossover Clinical Trial. J Clin Endocrinol Metab. 2020 08 01; 105(8).
-
Gwin JA, Church DD, Hatch-McChesney A, Howard EE, Carrigan CT, Murphy NE, Wilson MA, Margolis LM, Carbone JW, Wolfe RR, Ferrando AA, Pasiakos SM. Effects of high versus standard essential amino acid intakes on whole-body protein turnover and mixed muscle protein synthesis during energy deficit: A randomized, crossover study. Clin Nutr. 2021 03; 40(3):767-777.
-
Moleski SM, Shah A, Durney P, Matthews M, Kaushal G, Smith C, Koons KC, Rubin E, Casey P, Miller R, Miller C, Jawairia M, Hasan A, DiMarino AJ. Symptoms of gluten ingestion in patients with non-celiac gluten sensitivity: A randomized clinical trial. Nutrition. 2021 01; 81:110944.
-
Park S, Church DD, Azhar G, Schutzler SE, Ferrando AA, Wolfe RR. Anabolic response to essential amino acid plus whey protein composition is greater than whey protein alone in young healthy adults. J Int Soc Sports Nutr. 2020 Feb 10; 17(1):9.
-
Reisdorph NA, Hendricks AE, Tang M, Doenges KA, Reisdorph RM, Tooker BC, Quinn K, Borengasser SJ, Nkrumah-Elie Y, Frank DN, Campbell WW, Krebs NF. Nutrimetabolomics reveals food-specific compounds in urine of adults consuming a DASH-style diet. Sci Rep. 2020 01 24; 10(1):1157.
-
Jansen LT, Suh H, Adams JD, Sprong CA, Seal AD, Scott DM, Butts CL, Melander O, Kirkland TW, Vanhaecke T, Dolci A, Lemetais G, Perrier ET, Kavouras SA. Osmotic stimulation of vasopressin acutely impairs glucose regulation: a counterbalanced, crossover trial. Am J Clin Nutr. 2019 12 01; 110(6):1344-1352.
-
Solverson PM, Henderson TR, Debelo H, Ferruzzi MG, Baer DJ, Novotny JA. An Anthocyanin-Rich Mixed-Berry Intervention May Improve Insulin Sensitivity in a Randomized Trial of Overweight and Obese Adults. Nutrients. 2019 Nov 25; 11(12).
-
Maziak W, Ben Taleb Z, Ebrahimi Kalan M, Ward-Peterson M, Bursac Z, Osibogun O, Eissenberg T. Effect of flavour manipulation on low and high-frequency waterpipe users' puff topography, toxicant exposures and subjective experiences. Tob Control. 2020 02; 29(Suppl 2):s95-s101.
-
Goode GA, Wagh SJ, Irby DJ, Ma D, Jacobs RF, Kearns GL, Almoazen H. Bioavailability testing of a newly developed clindamycin oral suspension in a pediatric porcine model. Pharm Dev Technol. 2019 Oct; 24(8):1038-1043.
-
Elton A, Dove S, Spencer CN, Robinson DL, Boettiger CA. Naltrexone Acutely Enhances Connectivity Between the Ventromedial Prefrontal Cortex and a Left Frontoparietal Network. Alcohol Clin Exp Res. 2019 05; 43(5):965-978.
-
Stancil SL, Pearce RE, Tyndale RF, Kearns GL, Vyhlidal CA, Leeder JS, Abdel-Rahman S. Evaluating metronidazole as a novel, safe CYP2A6 phenotyping probe in healthy adults. Br J Clin Pharmacol. 2019 05; 85(5):960-969.
-
Adams JD, Scott DM, Brand NA, Suh HG, Seal AD, McDermott BP, Ganio MS, Kavouras SA. Mild hypohydration impairs cycle ergometry performance in the heat: A blinded study. Scand J Med Sci Sports. 2019 May; 29(5):686-695.
-
Hamarsland H, Aas SN, Nordengen AL, Holte K, Garthe I, Paulsen G, Cotter M, B?rsheim E, Benestad HB, Raastad T. Native Whey Induces Similar Post Exercise Muscle Anabolic Responses as Regular Whey, Despite Greater Leucinemia, in Elderly Individuals. J Nutr Health Aging. 2019; 23(1):42-50.
-
Ahmad AF, Rich L, Koch H, Croft KD, Ferruzzi MG, Kay CD, Hodgson JM, Ward NC. Effect of adding milk to black tea on vascular function in healthy men and women: a randomised controlled crossover trial. Food Funct. 2018 Dec 13; 9(12):6307-6314.
-
Jonker R, Deutz NEP, Schols AMWJ, Veley EA, Harrykissoon R, Zachria AJ, Engelen MPKJ. Whole body protein anabolism in COPD patients and healthy older adults is not enhanced by adding either carbohydrates or leucine to a serving of protein. Clin Nutr. 2019 08; 38(4):1684-1691.
-
Solverson PM, Rumpler WV, Leger JL, Redan BW, Ferruzzi MG, Baer DJ, Castonguay TW, Novotny JA. Blackberry Feeding Increases Fat Oxidation and Improves Insulin Sensitivity in Overweight and Obese Males. Nutrients. 2018 Aug 09; 10(8).
-
Schlienz NJ, Lee DC, Stitzer ML, Vandrey R. The effect of high-dose dronabinol (oral THC) maintenance on cannabis self-administration. Drug Alcohol Depend. 2018 06 01; 187:254-260.
-
Fairman BJ, Anthony JC. Does Starting to Smoke Cigars Trigger Onset of Cannabis Blunt Smoking? Nicotine Tob Res. 2018 02 07; 20(3):355-361.
-
Awad SM, Berlinski A. Crossover Evaluation of Compressors and Nebulizers Typically Used by Cystic Fibrosis Patients. Respir Care. 2018 Mar; 63(3):294-300.
-
Bhardwaj R, Dod H, Sandhu MS, Bedi R, Dod S, Konat G, Chopra HK, Sharma R, Jain AC, Nanda N. Acute effects of diets rich in almonds and walnuts on endothelial function. Indian Heart J. 2018 Jul - Aug; 70(4):497-501.
-
Haynes T, Turner J, Smith J, Curran G, Bryant-Moore K, Ounpraseuth ST, Kramer T, Harris K, Hutchins E, Yeary KHK. Reducing depressive symptoms through behavioral activation in churches: A Hybrid-2 randomized effectiveness-implementation design. Contemp Clin Trials. 2018 01; 64:22-29.
-
Hamarsland H, Nordengen AL, Nyvik Aas S, Holte K, Garthe I, Paulsen G, Cotter M, B?rsheim E, Benestad HB, Raastad T. Native whey protein with high levels of leucine results in similar post-exercise muscular anabolic responses as regular whey protein: a randomized controlled trial. J Int Soc Sports Nutr. 2017; 14:43.
-
Srivastava S, Mennemeier M, Pimple S. Effect of Alpinia galanga on Mental Alertness and Sustained Attention With or Without Caffeine: A Randomized Placebo-Controlled Study. J Am Coll Nutr. 2017 Nov-Dec; 36(8):631-639.
-
Chopra S, Rathore A, Younas H, Pham LV, Gu C, Beselman A, Kim IY, Wolfe RR, Perin J, Polotsky VY, Jun JC. Obstructive Sleep Apnea Dynamically Increases Nocturnal Plasma Free Fatty Acids, Glucose, and Cortisol During Sleep. J Clin Endocrinol Metab. 2017 09 01; 102(9):3172-3181.
-
James GA, Thostenson JD, Brown G, Carter G, Hayes H, Tripathi SP, Dobry DJ, Govindan RB, Dornhoffer JL, Williams DK, Kilts CD, Mennemeier MS. Neural activity during attentional conflict predicts reduction in tinnitus perception following rTMS. Brain Stimul. 2017 Sep - Oct; 10(5):934-943.
-
Hanlon CA, Dowdle LT, Correia B, Mithoefer O, Kearney-Ramos T, Lench D, Griffin M, Anton RF, George MS. Left frontal pole theta burst stimulation decreases orbitofrontal and insula activity in cocaine users and alcohol users. Drug Alcohol Depend. 2017 09 01; 178:310-317.
-
Mathis WS, Han X. The acute effect of pleasurable music on craving for alcohol: A pilot crossover study. J Psychiatr Res. 2017 07; 90:143-147.
-
Tolbert JA, Bai S, Abdel-Rahman SM, August KJ, Weir SJ, Kearns GL, Neville KA. Pharmacokinetics of two 6-mercaptopurine liquid formulations in children with acute lymphoblastic leukemia. Pediatr Blood Cancer. 2017 Aug; 64(8).
-
Jonker R, Deutz NE, Erbland ML, Anderson PJ, Engelen MP. Effectiveness of essential amino acid supplementation in stimulating whole body net protein anabolism is comparable between COPD patients and healthy older adults. Metabolism. 2017 Apr; 69:120-129.
-
Berlinski A, von Hollen D, Hatley RHM, Hardaker LEA, Nikander K. Drug Delivery in Asthmatic Children Following Coordinated and Uncoordinated Inhalation Maneuvers: A Randomized Crossover Trial. J Aerosol Med Pulm Drug Deliv. 2017 Jun; 30(3):182-189.
-
Kim JE, Ferruzzi MG, Campbell WW. Egg Consumption Increases Vitamin E Absorption from Co-Consumed Raw Mixed Vegetables in Healthy Young Men. J Nutr. 2016 Nov; 146(11):2199-2205.
-
Kinsey AW, Cappadona SR, Panton LB, Allman BR, Contreras RJ, Hickner RC, Ormsbee MJ. The Effect of Casein Protein Prior to Sleep on Fat Metabolism in Obese Men. Nutrients. 2016 Jul 27; 8(8).
-
Wells AJ, Hoffman JR, Jajtner AR, Varanoske AN, Church DD, Gonzalez AM, Townsend JR, Boone CH, Baker KM, Beyer KS, Mangine GT, Oliveira LP, Fukuda DH, Stout JR. The Effect of Post-Resistance Exercise Amino Acids on Plasma MCP-1 and CCR2 Expression. Nutrients. 2016 Jul 02; 8(7).
-
Arnaoutis G, Kavouras SA, Stratakis N, Likka M, Mitrakou A, Papamichael C, Sidossis LS, Stamatelopoulos K. The effect of hypohydration on endothelial function in young healthy adults. Eur J Nutr. 2017 Apr; 56(3):1211-1217.
-
Hazim S, Curtis PJ, Sch?r MY, Ostertag LM, Kay CD, Minihane AM, Cassidy A. Acute benefits of the microbial-derived isoflavone metabolite equol on arterial stiffness in men prospectively recruited according to equol producer phenotype: a double-blind randomized controlled trial. Am J Clin Nutr. 2016 Mar; 103(3):694-702.
-
Rajan S, Khanna A, Argalious M, Kimatian SJ, Mascha EJ, Makarova N, Nada EM, Elsharkawy H, Firoozbakhsh F, Avitsian R. Comparison of 2 resident learning tools-interactive screen-based simulated case scenarios versus problem-based learning discussions: a prospective quasi-crossover cohort study. J Clin Anesth. 2016 Feb; 28:4-11.
-
Church DD, Hoffman JR, LaMonica MB, Riffe JJ, Hoffman MW, Baker KM, Varanoske AN, Wells AJ, Fukuda DH, Stout JR. The effect of an acute ingestion of Turkish coffee on reaction time and time trial performance. J Int Soc Sports Nutr. 2015; 12:37.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|