 Multigene Family
"Multigene Family" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A set of genes descended by duplication and variation from some ancestral gene. Such genes may be clustered together on the same chromosome or dispersed on different chromosomes. Examples of multigene families include those that encode the hemoglobins, immunoglobulins, histocompatibility antigens, actins, tubulins, keratins, collagens, heat shock proteins, salivary glue proteins, chorion proteins, cuticle proteins, yolk proteins, and phaseolins, as well as histones, ribosomal RNA, and transfer RNA genes. The latter three are examples of reiterated genes, where hundreds of identical genes are present in a tandem array. (King & Stanfield, A Dictionary of Genetics, 4th ed)
| Descriptor ID |
D005810
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| MeSH Number(s) |
G05.360.340.024.340.645
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| Concept/Terms |
Multigene Family- Multigene Family
- Families, Multigene
- Family, Multigene
- Multigene Families
Gene Clusters- Gene Clusters
- Cluster, Gene
- Clusters, Gene
- Gene Cluster
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Below are MeSH descriptors whose meaning is more general than "Multigene Family".
Below are MeSH descriptors whose meaning is more specific than "Multigene Family".
This graph shows the total number of publications written about "Multigene Family" by people in UAMS Profiles by year, and whether "Multigene Family" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 | | 2019 | 1 | 0 | 1 | | 2018 | 0 | 1 | 1 | | 2015 | 2 | 2 | 4 | | 2013 | 2 | 0 | 2 | | 2012 | 0 | 3 | 3 | | 2011 | 0 | 1 | 1 | | 2010 | 0 | 2 | 2 | | 2009 | 0 | 2 | 2 | | 2007 | 2 | 2 | 4 | | 2006 | 0 | 4 | 4 | | 2005 | 0 | 1 | 1 | | 2003 | 0 | 3 | 3 | | 2002 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 1997 | 2 | 1 | 3 | | 1996 | 1 | 1 | 2 | | 1992 | 0 | 2 | 2 |
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Below are the most recent publications written about "Multigene Family" by people in Profiles over the past ten years.
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Wissinger B, Baumann B, Buena-Atienza E, Ravesh Z, Cideciyan AV, Stingl K, Audo I, Meunier I, Bocquet B, Traboulsi EI, Hardcastle AJ, Gardner JC, Michaelides M, Branham KE, Rosenberg T, Andreasson S, Dollfus H, Birch D, Vincent AL, Martorell L, Catal? Mora J, Kellner U, R?ther K, Lorenz B, Preising MN, Manfredini E, Zarate YA, Vijzelaar R, Zrenner E, Jacobson SG, Kohl S. The landscape of submicroscopic structural variants at the OPN1LW/OPN1MW gene cluster on Xq28 underlying blue cone monochromacy. Proc Natl Acad Sci U S A. 2022 07 05; 119(27):e2115538119.
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Adams MK, Banks CAS, Thornton JL, Kempf CG, Zhang Y, Miah S, Hao Y, Sardiu ME, Killer M, Hattem GL, Murray A, Katt ML, Florens L, Washburn MP. Differential Complex Formation via Paralogs in the Human Sin3 Protein Interaction Network. Mol Cell Proteomics. 2020 09; 19(9):1468-1484.
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Tait Wojno ED, Hunter CA, Stumhofer JS. The Immunobiology of the Interleukin-12 Family: Room for Discovery. Immunity. 2019 04 16; 50(4):851-870.
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Brunson JK, McKinnie SMK, Chekan JR, McCrow JP, Miles ZD, Bertrand EM, Bielinski VA, Luhavaya H, Oborn?k M, Smith GJ, Hutchins DA, Allen AE, Moore BS. Biosynthesis of the neurotoxin domoic acid in a bloom-forming diatom. Science. 2018 09 28; 361(6409):1356-1358.
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Arlt VM, Meinl W, Florian S, Nagy E, Barta F, Thomann M, Mrizova I, Krais AM, Liu M, Richards M, Mirza A, Kopka K, Phillips DH, Glatt H, Stiborova M, Schmeiser HH. Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone. Arch Toxicol. 2017 Apr; 91(4):1957-1975.
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Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, D?sterhus S, Edwards DJ, Fewer DP, Garg N, Geiger C, Gomez-Escribano JP, Greule A, Hadjithomas M, Haines AS, Helfrich EJ, Hillwig ML, Ishida K, Jones AC, Jones CS, Jungmann K, Kegler C, Kim HU, K?tter P, Krug D, Masschelein J, Melnik AV, Mantovani SM, Monroe EA, Moore M, Moss N, N?tzmann HW, Pan G, Pati A, Petras D, Reen FJ, Rosconi F, Rui Z, Tian Z, Tobias NJ, Tsunematsu Y, Wiemann P, Wyckoff E, Yan X, Yim G, Yu F, Xie Y, Aigle B, Apel AK, Balibar CJ, Balskus EP, Barona-G?mez F, Bechthold A, Bode HB, Borriss R, Brady SF, Brakhage AA, Caffrey P, Cheng YQ, Clardy J, Cox RJ, De Mot R, Donadio S, Donia MS, van der Donk WA, Dorrestein PC, Doyle S, Driessen AJ, Ehling-Schulz M, Entian KD, Fischbach MA, Gerwick L, Gerwick WH, Gross H, Gust B, Hertweck C, H?fte M, Jensen SE, Ju J, Katz L, Kaysser L, Klassen JL, Keller NP, Kormanec J, Kuipers OP, Kuzuyama T, Kyrpides NC, Kwon HJ, Lautru S, Lavigne R, Lee CY, Linquan B, Liu X, Liu W, Luzhetskyy A, Mahmud T, Mast Y, M?ndez C, Mets?-Ketel? M, Micklefield J, Mitchell DA, Moore BS, Moreira LM, M?ller R, Neilan BA, Nett M, Nielsen J, O'Gara F, Oikawa H, Osbourn A, Osburne MS, Ostash B, Payne SM, Pernodet JL, Petricek M, Piel J, Ploux O, Raaijmakers JM, Salas JA, Schmitt EK, Scott B, Seipke RF, Shen B, Sherman DH, Sivonen K, Smanski MJ, Sosio M, Stegmann E, S?ssmuth RD, Tahlan K, Thomas CM, Tang Y, Truman AW, Viaud M, Walton JD, Walsh CT, Weber T, van Wezel GP, Wilkinson B, Willey JM, Wohlleben W, Wright GD, Ziemert N, Zhang C, Zotchev SB, Breitling R, Takano E, Gl?ckner FO. Minimum Information about a Biosynthetic Gene cluster. Nat Chem Biol. 2015 Sep; 11(9):625-31.
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Mart?n-Moldes Z, Zamarro MT, Del Cerro C, Valencia A, G?mez MJ, Arcas A, Udaondo Z, Garc?a JL, Nogales J, Carmona M, D?az E. Whole-genome analysis of Azoarcus sp. strain CIB provides genetic insights to its different lifestyles and predicts novel metabolic features. Syst Appl Microbiol. 2015 Oct; 38(7):462-71.
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Espinoza-Valles I, Vora GJ, Lin B, Leekitcharoenphon P, Gonz?lez-Castillo A, Ussery D, H?j L, Gomez-Gil B. Unique and conserved genome regions in Vibrio harveyi and related species in comparison with the shrimp pathogen Vibrio harveyi CAIM 1792. Microbiology (Reading). 2015 Sep; 161(9):1762-1779.
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Abdelmohsen UR, Grkovic T, Balasubramanian S, Kamel MS, Quinn RJ, Hentschel U. Elicitation of secondary metabolism in actinomycetes. Biotechnol Adv. 2015 Nov 01; 33(6 Pt 1):798-811.
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Cai W, Goswami A, Yang Z, Liu X, Green KD, Barnard-Britson S, Baba S, Funabashi M, Nonaka K, Sunkara M, Morris AJ, Spork AP, Ducho C, Garneau-Tsodikova S, Thorson JS, Van Lanen SG. The Biosynthesis of Capuramycin-type Antibiotics: IDENTIFICATION OF THE A-102395 BIOSYNTHETIC GENE CLUSTER, MECHANISM OF SELF-RESISTANCE, AND FORMATION OF URIDINE-5'-CARBOXAMIDE. J Biol Chem. 2015 May 29; 290(22):13710-24.
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