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Andrew Morris

TitleProfessor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentPharmacology and Toxicology, College of Medicine
Address110C BIOMED
4301 W. Markham
Mail Slot # 611
Little Rock AR 72205
ORCID ORCID Icon0000-0003-1910-4865 Additional info
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    Collapse Research 
    Collapse research activities and funding
    IK6BX006469     (MORRIS, ANDREW J)Oct 1, 2023 - Sep 30, 2028
    NIH
    BLRD Research Career Scientist Award Application
    Role: Principal Investigator
    1R37CA282349     (FIL, AMANDA J)Aug 10, 2023 - Jul 31, 2028
    NIH/Nat. Cancer Institute
    Ryanodine Receptors as Therapeutic Targets to Prevent Doxorubicin-Induced Lymphatic Dysfunction
    Role: Principal Investigator
    I01BX005637     (MORRIS, ANDREW J)Apr 1, 2021 - Mar 31, 2025
    NIH
    Lysophosphatidic Acid and Cardiovascular Disease Risk
    Role: Principal Investigator
    I01BX004671     (MORRIS, ANDREW J)Apr 1, 2020 - Jun 30, 2025
    NIH
    Serum Amyloid as a Critical mediator between inflammation and thrombosis
    Role: Principal Investigator
    IS1BX004791     (MORRIS, ANDREW J)Jan 1, 2019 - Sep 30, 2019
    NIH
    ShEEP Request For Gas Chromatograph Mass Spectrometer
    Role: Principal Investigator
    S10OD021753     (MORRIS, ANDREW J)Mar 15, 2017 - Mar 14, 2018
    NIH
    Triple Quadrupole Mass Spectrometer System
    Role: Principal Investigator
    R01HL120507     (SMYTH, SUSAN S.)Apr 1, 2015 - Mar 31, 2021
    NIH
    Lipid phosphate phosphatase 3 as a novel atherosclerosis suppressor
    Role: Co-Principal Investigator
    IS1BX003153     (MORRIS, ANDREW J)Apr 1, 2015 - Sep 30, 2015
    NIH
    Acquisition of an HPLC Electrospray/chemical ionization triple quadrupole linear ion trap mass spectrometer system.
    Role: Principal Investigator
    I01CX001550     (MORRIS, ANDREW J)Jan 1, 2013 - Dec 31, 2020
    NIH
    Lysophosphatidic acid and cardiovascular disease risk
    Role: Principal Investigator
    I01BX001984     (MORRIS, ANDREW J)Jan 1, 2013 - Dec 31, 2016
    NIH
    Association of a common variant of the PPAP2B gene with cardiovascular disease.
    Role: Principal Investigator
    S10RR026884     (MORRIS, ANDREW J)May 1, 2011 - Apr 30, 2012
    NIH
    Advion Triversa Nanomate/ABSciex Nanospray III Ion Source for Targeted Lipidomics
    Role: Principal Investigator
    S10RR024598     (MORRIS, ANDREW J)Mar 1, 2008 - Feb 28, 2009
    NIH
    Thermo/Finnigan TSQ AM Triple Stage Quadrupole Mass Spectrometer
    Role: Principal Investigator
    R13HL082350     (MORRIS, ANDREW J)Aug 1, 2005 - Jul 31, 2006
    NIH
    FASEB SUMMER RESEARCH CONFERENCE: BIOACTIVE LYSOLIPIDS
    Role: Principal Investigator
    R13AI062394     (MORRIS, ANDREW J)Jul 15, 2004 - Jun 30, 2005
    NIH
    FASEB Summer Conference on Phospholipases
    Role: Principal Investigator
    R01CA096496     (MORRIS, ANDREW J)Feb 1, 2002 - Jan 31, 2008
    NIH
    Lysophospholipid Mediators in Ovarian Cancer
    Role: Principal Investigator
    S10RR012856     (MORRIS, ANDREW J)Jan 21, 1999 - Jan 20, 2000
    NIH
    BIACORE 2000 SURFACE PLASMON RESONANCE BIOSENSOR
    Role: Principal Investigator
    R55GM054641     (MORRIS, ANDREW J)Sep 15, 1996 - Sep 14, 1999
    NIH
    REGULATION OF PHOSPHOLIPASE D
    Role: Principal Investigator
    R01GM050388     (MORRIS, ANDREW J)Aug 1, 1994 - Jun 30, 2014
    NIH
    Role of Lipid Phosphatases in Cholesterol and Triglyceride Synthesis
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Sims CR, Sehgal N, Turner D, Havens LA, Morris AJ, Shankar K, Pearson KJ, Everson TM, Andres A. Individual and mixtures of PFAS during pregnancy are associated with maternal cardiometabolic outcomes during pregnancy. Environ Health. 2025 Apr 30; 24(1):26. PMID: 40307774.
      View in: PubMed
    2. Hameed A, Ferruzzi MG, Kay CD, Williams DK, Rahbar E, Morris AJ. Comparison of the capillary and venous blood plasma lipidomes: validation of self-collected blood for plasma lipidomics. J Lipid Res. 2025 Mar; 66(3):100755. PMID: 39952568.
      View in: PubMed
    3. Wang S, Jin Z, Wu B, Morris AJ, Deng P. Role of dietary and nutritional interventions in ceramide-associated diseases. J Lipid Res. 2025 Jan; 66(1):100726. PMID: 39667580.
      View in: PubMed
    4. Prabakaran AD, McFarland K, Miz K, Durumutla HB, Piczer K, El Abdellaoui Soussi F, Latimer H, Werbrich C, Chung HJ, Blair NS, Millay DP, Morris AJ, Prideaux B, Finck BN, Quattrocelli M. Intermittent glucocorticoid treatment improves muscle metabolism via the PGC1a/Lipin1 axis in an aging-related sarcopenia model. J Clin Invest. 2024 May 03; 134(11). PMID: 38702076.
      View in: PubMed
    5. Morgan S, Mottaleb MA, Kraemer MP, Moser DK, Worley J, Morris AJ, Petriello MC. Effect of lifestyle-based lipid lowering interventions on the relationship between circulating levels of per-and polyfluoroalkyl substances and serum cholesterol. Environ Toxicol Pharmacol. 2023 Mar; 98:104062. PMID: 36621559.
      View in: PubMed
    6. Petriello MC, Mottaleb MA, Serio TC, Balyan B, Cave MC, Pavuk M, Birnbaum LS, Morris AJ. Serum concentrations of legacy and emerging per- and polyfluoroalkyl substances in the Anniston Community Health Surveys (ACHS I and ACHS II). Environ Int. 2022 01; 158:106907. PMID: 34763231.
      View in: PubMed
    7. Deng P, Wang C, Wahlang B, Sexton T, Morris AJ, Hennig B. Co-exposure to PCB126 and PFOS increases biomarkers associated with cardiovascular disease risk and liver injury in mice. Toxicol Appl Pharmacol. 2020 12 15; 409:115301. PMID: 33096110.
      View in: PubMed
    8. Mottaleb MA, Petriello MC, Morris AJ. High-Throughput UHPLC-MS/MS Measurement of Per- and Poly-Fluorinated Alkyl Substances in Human Serum. J Anal Toxicol. 2020 May 18; 44(4):339-347. PMID: 31776573.
      View in: PubMed
    9. Smyth SS, Kraemer M, Yang L, Van Hoose P, Morris AJ. Roles for lysophosphatidic acid signaling in vascular development and disease. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 08; 1865(8):158734. PMID: 32376340.
      View in: PubMed
    10. Deng P, Hoffman JB, Petriello MC, Wang CY, Li XS, Kraemer MP, Morris AJ, Hennig B. Dietary inulin decreases circulating ceramides by suppressing neutral sphingomyelinase expression and activity in mice. J Lipid Res. 2020 01; 61(1):45-53. PMID: 31604806.
      View in: PubMed
    11. Kraemer MP, Mao G, Hammill C, Yan B, Li Y, Onono F, Smyth SS, Morris AJ. Effects of diet and hyperlipidemia on levels and distribution of circulating lysophosphatidic acid. J Lipid Res. 2019 11; 60(11):1818-1828. PMID: 31484695.
      View in: PubMed
    12. Jackson EN, Thatcher SE, Larian N, English V, Soman S, Morris AJ, Weng J, Stromberg A, Swanson HI, Pearson K, Cassis LA. Effects of Aryl Hydrocarbon Receptor Deficiency on PCB-77-Induced Impairment of Glucose Homeostasis during Weight Loss in Male and Female Obese Mice. Environ Health Perspect. 2019 07; 127(7):77004. PMID: 31306034.
      View in: PubMed
    13. Yang L, Kraemer M, Fang XF, Angel PM, Drake RR, Morris AJ, Smyth SS. LPA receptor 4 deficiency attenuates experimental atherosclerosis. J Lipid Res. 2019 05; 60(5):972-980. PMID: 30796085.
      View in: PubMed
    14. D'Souza K, Nzirorera C, Cowie AM, Varghese GP, Trivedi P, Eichmann TO, Biswas D, Touaibia M, Morris AJ, Aidinis V, Kane DA, Pulinilkunnil T, Kienesberger PC. Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism. J Lipid Res. 2018 10; 59(10):1805-1817. PMID: 30072447.
      View in: PubMed
    15. Petriello MC, Hoffman JB, Vsevolozhskaya O, Morris AJ, Hennig B. Dioxin-like PCB 126 increases intestinal inflammation and disrupts gut microbiota and metabolic homeostasis. Environ Pollut. 2018 Nov; 242(Pt A):1022-1032. PMID: 30373033.
      View in: PubMed
    16. Federico L, Yang L, Brandon J, Panchatcharam M, Ren H, Mueller P, Sunkara M, Escalante-Alcalde D, Morris AJ, Smyth SS. Lipid phosphate phosphatase 3 regulates adipocyte sphingolipid synthesis, but not developmental adipogenesis or diet-induced obesity in mice. PLoS One. 2018; 13(6):e0198063. PMID: 29889835.
      View in: PubMed
    17. Petriello MC, Charnigo R, Sunkara M, Soman S, Pavuk M, Birnbaum L, Morris AJ, Hennig B. Relationship between serum trimethylamine N-oxide and exposure to dioxin-like pollutants. Environ Res. 2018 04; 162:211-218. PMID: 29353125.
      View in: PubMed
    18. Kraemer MP, Halder S, Smyth SS, Morris AJ. Measurement of Lysophosphatidic Acid and Sphingosine-1-Phosphate by Liquid Chromatography-Coupled Electrospray Ionization Tandem Mass Spectrometry. Methods Mol Biol. 2018; 1697:31-42. PMID: 28770493.
      View in: PubMed
    19. Tang S, Floy M, Bhandari R, Sunkara M, Morris AJ, Dziubla TD, Hilt JZ. Synthesis and Characterization of Thermoresponsive Hydrogels Based on N-Isopropylacrylamide Crosslinked with 4,4'-Dihydroxybiphenyl Diacrylate. ACS Omega. 2017 Dec 31; 2(12):8723-8729. PMID: 29302630.
      View in: PubMed
    20. Patil VS, Gutierrez AM, Sunkara M, Morris AJ, Hilt JZ, Kalika DS, Dziubla TD. Curcumin Acrylation for Biological and Environmental Applications. J Nat Prod. 2017 07 28; 80(7):1964-1971. PMID: 28661687.
      View in: PubMed
    21. Shaaban KA, Saunders MA, Zhang Y, Tran T, Elshahawi SI, Ponomareva LV, Wang X, Zhang J, Copley GC, Sunkara M, Kharel MK, Morris AJ, Hower JC, Tremblay MS, Prendergast MA, Thorson JS. Spoxazomicin D and Oxachelin C, Potent Neuroprotective Carboxamides from the Appalachian Coal Fire-Associated Isolate Streptomyces sp. RM-14-6. J Nat Prod. 2017 01 27; 80(1):2-11. PMID: 28029795.
      View in: PubMed
    22. Zhang J, Hughes RR, Saunders MA, Elshahawi SI, Ponomareva LV, Zhang Y, Winchester SR, Scott SA, Sunkara M, Morris AJ, Prendergast MA, Shaaban KA, Thorson JS. Identification of Neuroprotective Spoxazomicin and Oxachelin Glycosides via Chemoenzymatic Glycosyl-Scanning. J Nat Prod. 2017 01 27; 80(1):12-18. PMID: 28029796.
      View in: PubMed
    23. Morris AJ, Smyth SS. Regulation of Lysophosphatidic Acid Metabolism and Signaling by Lipoproteins. Arterioscler Thromb Vasc Biol. 2016 10; 36(10):2029-30. PMID: 27655776.
      View in: PubMed
    24. Huber TD, Wang F, Singh S, Johnson BR, Zhang J, Sunkara M, Van Lanen SG, Morris AJ, Phillips GN, Thorson JS. Functional AdoMet Isosteres Resistant to Classical AdoMet Degradation Pathways. ACS Chem Biol. 2016 09 16; 11(9):2484-91. PMID: 27351335.
      View in: PubMed
    25. Keune WJ, Hausmann J, Bolier R, Tolenaars D, Kremer A, Heidebrecht T, Joosten RP, Sunkara M, Morris AJ, Matas-Rico E, Moolenaar WH, Oude Elferink RP, Perrakis A. Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling. Nat Commun. 2016 Apr 14; 7:11248. PMID: 27075612.
      View in: PubMed
    26. Petriello MC, Hoffman JB, Sunkara M, Wahlang B, Perkins JT, Morris AJ, Hennig B. Dioxin-like pollutants increase hepatic flavin containing monooxygenase (FMO3) expression to promote synthesis of the pro-atherogenic nutrient biomarker trimethylamine N-oxide from dietary precursors. J Nutr Biochem. 2016 07; 33:145-53. PMID: 27155921.
      View in: PubMed
    27. Albayati ZA, Sunkara M, Schmidt-Malan SM, Karau MJ, Morris AJ, Steckelberg JM, Patel R, Breen PJ, Smeltzer MS, Taylor KG, Merten KE, Pierce WM, Crooks PA. Novel Bone-Targeting Agent for Enhanced Delivery of Vancomycin to Bone. Antimicrob Agents Chemother. 2015 Dec 14; 60(3):1865-8. PMID: 26666918.
      View in: PubMed
    28. Wang X, Reynolds AR, Elshahawi SI, Shaaban KA, Ponomareva LV, Saunders MA, Elgumati IS, Zhang Y, Copley GC, Hower JC, Sunkara M, Morris AJ, Kharel MK, Van Lanen SG, Prendergast MA, Thorson JS. Correction to "Terfestatins B and C, New p-Terphenyl Glycosides Produced by Streptomyces sp. RM-5-8". Org Lett. 2015 Nov 06; 17(21):5515. PMID: 26458135.
      View in: PubMed
    29. Klyachkin YM, Nagareddy PR, Ye S, Wysoczynski M, Asfour A, Gao E, Sunkara M, Brandon JA, Annabathula R, Ponnapureddy R, Solanki M, Pervaiz ZH, Smyth SS, Ratajczak MZ, Morris AJ, Abdel-Latif A. Pharmacological Elevation of Circulating Bioactive Phosphosphingolipids Enhances Myocardial Recovery After Acute Infarction. Stem Cells Transl Med. 2015 Nov; 4(11):1333-43. PMID: 26371341.
      View in: PubMed
    30. Zhang W, Deng J, Sunkara M, Morris AJ, Wang C, St Clair D, Vore M. Loss of multidrug resistance-associated protein 1 potentiates chronic doxorubicin-induced cardiac dysfunction in mice. J Pharmacol Exp Ther. 2015 Nov; 355(2):280-7. PMID: 26354995.
      View in: PubMed
    31. Deng J, Coy D, Zhang W, Sunkara M, Morris AJ, Wang C, Chaiswing L, St Clair D, Vore M, Jungsuwadee P. Elevated glutathione is not sufficient to protect against doxorubicin-induced nuclear damage in heart in multidrug resistance-associated protein 1 (Mrp1/Abcc1) null mice. J Pharmacol Exp Ther. 2015 Nov; 355(2):272-9. PMID: 26354996.
      View in: PubMed
    32. Wang X, Reynolds AR, Elshahawi SI, Shaaban KA, Ponomareva LV, Saunders MA, Elgumati IS, Zhang Y, Copley GC, Hower JC, Sunkara M, Morris AJ, Kharel MK, Van Lanen SG, Prendergast MA, Thorson JS. Terfestatins B and C, New p-Terphenyl Glycosides Produced by Streptomyces sp. RM-5-8. Org Lett. 2015 Jun 05; 17(11):2796-9. PMID: 25961722.
      View in: PubMed
    33. Cai W, Goswami A, Yang Z, Liu X, Green KD, Barnard-Britson S, Baba S, Funabashi M, Nonaka K, Sunkara M, Morris AJ, Spork AP, Ducho C, Garneau-Tsodikova S, Thorson JS, Van Lanen SG. The Biosynthesis of Capuramycin-type Antibiotics: IDENTIFICATION OF THE A-102395 BIOSYNTHETIC GENE CLUSTER, MECHANISM OF SELF-RESISTANCE, AND FORMATION OF URIDINE-5'-CARBOXAMIDE. J Biol Chem. 2015 May 29; 290(22):13710-24. PMID: 25855790.
      View in: PubMed
    34. Walton RG, Zhu B, Unal R, Spencer M, Sunkara M, Morris AJ, Charnigo R, Katz WS, Daugherty A, Howatt DA, Kern PA, Finlin BS. Increasing adipocyte lipoprotein lipase improves glucose metabolism in high fat diet-induced obesity. J Biol Chem. 2015 May 01; 290(18):11547-56. PMID: 25784555.
      View in: PubMed
    35. Baker NA, Shoemaker R, English V, Larian N, Sunkara M, Morris AJ, Walker M, Yiannikouris F, Cassis LA. Effects of Adipocyte Aryl Hydrocarbon Receptor Deficiency on PCB-Induced Disruption of Glucose Homeostasis in Lean and Obese Mice. Environ Health Perspect. 2015 Oct; 123(10):944-50. PMID: 25734695.
      View in: PubMed
    36. Siow D, Sunkara M, Dunn TM, Morris AJ, Wattenberg B. ORMDL/serine palmitoyltransferase stoichiometry determines effects of ORMDL3 expression on sphingolipid biosynthesis. J Lipid Res. 2015 Apr; 56(4):898-908. PMID: 25691431.
      View in: PubMed
    37. Murphy MO, Petriello MC, Han SG, Sunkara M, Morris AJ, Esser K, Hennig B. Exercise protects against PCB-induced inflammation and associated cardiovascular risk factors. Environ Sci Pollut Res Int. 2016 Feb; 23(3):2201-11. PMID: 25586614.
      View in: PubMed
    38. Morris AJ, Smyth SS. Lipid phosphate phosphatases: more than one way to put the brakes on LPA signaling? J Lipid Res. 2014 Nov; 55(11):2195-7. PMID: 25271297.
      View in: PubMed
    39. Siow D, Sunkara M, Morris A, Wattenberg B. Regulation of de novo sphingolipid biosynthesis by the ORMDL proteins and sphingosine kinase-1. Adv Biol Regul. 2015 Jan; 57:42-54. PMID: 25319495.
      View in: PubMed
    40. Jonnalagadda D, Sunkara M, Morris AJ, Whiteheart SW. Granule-mediated release of sphingosine-1-phosphate by activated platelets. Biochim Biophys Acta. 2014 Nov; 1841(11):1581-9. PMID: 25158625.
      View in: PubMed
    41. Subramanian T, Ren H, Subramanian KL, Sunkara M, Onono FO, Morris AJ, Spielmann HP. Design and synthesis of non-hydrolyzable homoisoprenoid a-monofluorophosphonate inhibitors of PPAPDC family integral membrane lipid phosphatases. Bioorg Med Chem Lett. 2014 Sep 15; 24(18):4414-4417. PMID: 25150376.
      View in: PubMed
    42. Deevska G, Sunkara M, Karakashian C, Peppers B, Morris AJ, Nikolova-Karakashian MN. Effect of procysteine on aging-associated changes in hepatic GSH and SMase: evidence for transcriptional regulation of smpd3. J Lipid Res. 2014 Oct; 55(10):2041-52. PMID: 25047167.
      View in: PubMed
    43. Sui Y, Park SH, Helsley RN, Sunkara M, Gonzalez FJ, Morris AJ, Zhou C. Bisphenol A increases atherosclerosis in pregnane X receptor-humanized ApoE deficient mice. J Am Heart Assoc. 2014 Apr 22; 3(2):e000492. PMID: 24755147.
      View in: PubMed
    44. Wang X, Shaaban KA, Elshahawi SI, Ponomareva LV, Sunkara M, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS. Mullinamides A and B, new cyclopeptides produced by the Ruth Mullins coal mine fire isolate Streptomyces sp. RM-27-46. J Antibiot (Tokyo). 2014 Aug; 67(8):571-5. PMID: 24713874.
      View in: PubMed
    45. Wang F, Singh S, Zhang J, Huber TD, Helmich KE, Sunkara M, Hurley KA, Goff RD, Bingman CA, Morris AJ, Thorson JS, Phillips GN. Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus?solfataricus. FEBS J. 2014 Sep; 281(18):4224-39. PMID: 24649856.
      View in: PubMed
    46. Zhang J, Singh S, Hughes RR, Zhou M, Sunkara M, Morris AJ, Thorson JS. A simple strategy for glycosyltransferase-catalyzed aminosugar nucleotide synthesis. Chembiochem. 2014 Mar 21; 15(5):647-52. PMID: 24677528.
      View in: PubMed
    47. Singh S, Zhang J, Huber TD, Sunkara M, Hurley K, Goff RD, Wang G, Zhang W, Liu C, Rohr J, Van Lanen SG, Morris AJ, Thorson JS. Facile chemoenzymatic strategies for the synthesis and utilization of S-adenosyl-(L)-methionine analogues. Angew Chem Int Ed Engl. 2014 Apr 07; 53(15):3965-9. PMID: 24616228.
      View in: PubMed
    48. Panchatcharam M, Salous AK, Brandon J, Miriyala S, Wheeler J, Patil P, Sunkara M, Morris AJ, Escalante-Alcalde D, Smyth SS. Mice with targeted inactivation of ppap2b in endothelial and hematopoietic cells display enhanced vascular inflammation and permeability. Arterioscler Thromb Vasc Biol. 2014 Apr; 34(4):837-45. PMID: 24504738.
      View in: PubMed
    49. Smyth SS, Mueller P, Yang F, Brandon JA, Morris AJ. Arguing the case for the autotaxin-lysophosphatidic acid-lipid phosphate phosphatase 3-signaling nexus in the development and complications of atherosclerosis. Arterioscler Thromb Vasc Biol. 2014 Mar; 34(3):479-86. PMID: 24482375.
      View in: PubMed
    50. Baker NA, English V, Sunkara M, Morris AJ, Pearson KJ, Cassis LA. Resveratrol protects against polychlorinated biphenyl-mediated impairment of glucose homeostasis in adipocytes. J Nutr Biochem. 2013 Dec; 24(12):2168-74. PMID: 24231106.
      View in: PubMed
    51. Shaaban KA, Singh S, Elshahawi SI, Wang X, Ponomareva LV, Sunkara M, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS. The native production of the sesquiterpene isopterocarpolone by Streptomyces sp. RM-14-6. Nat Prod Res. 2014; 28(5):337-9. PMID: 24237421.
      View in: PubMed
    52. Shaaban KA, Singh S, Elshahawi SI, Wang X, Ponomareva LV, Sunkara M, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS. Venturicidin C, a new 20-membered macrolide produced by Streptomyces sp. TS-2-2. J Antibiot (Tokyo). 2014 Mar; 67(3):223-30. PMID: 24252813.
      View in: PubMed
    53. Newsome BJ, Petriello MC, Han SG, Murphy MO, Eske KE, Sunkara M, Morris AJ, Hennig B. Green tea diet decreases PCB 126-induced oxidative stress in mice by up-regulating antioxidant enzymes. J Nutr Biochem. 2014 Feb; 25(2):126-35. PMID: 24378064.
      View in: PubMed
    54. Gilbert MR, Liu Y, Neltner J, Pu H, Morris A, Sunkara M, Pittman T, Kyprianou N, Horbinski C. Autophagy and oxidative stress in gliomas with IDH1 mutations. Acta Neuropathol. 2014 Feb; 127(2):221-33. PMID: 24150401.
      View in: PubMed
    55. Zhang Y, Wang X, Sunkara M, Ye Q, Ponomereva LV, She QB, Morris AJ, Thorson JS. A diastereoselective oxa-Pictet-Spengler-based strategy for (+)-frenolicin B and epi-(+)-frenolicin B synthesis. Org Lett. 2013 Nov 01; 15(21):5566-9. PMID: 24151973.
      View in: PubMed
    56. Shaaban KA, Wang X, Elshahawi SI, Ponomareva LV, Sunkara M, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS. Herbimycins D-F, ansamycin analogues from Streptomyces sp. RM-7-15. J Nat Prod. 2013 Sep 27; 76(9):1619-26. PMID: 23947794.
      View in: PubMed
    57. Salous AK, Panchatcharam M, Sunkara M, Mueller P, Dong A, Wang Y, Graf GA, Smyth SS, Morris AJ. Mechanism of rapid elimination of lysophosphatidic acid and related lipids from the circulation of mice. J Lipid Res. 2013 Oct; 54(10):2775-84. PMID: 23948545.
      View in: PubMed
    58. Wang X, Shaaban KA, Elshahawi SI, Ponomareva LV, Sunkara M, Zhang Y, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS. Frenolicins C-G, pyranonaphthoquinones from Streptomyces sp. RM-4-15. J Nat Prod. 2013 Aug 23; 76(8):1441-7. PMID: 23944931.
      View in: PubMed
    59. Onono F, Subramanian T, Sunkara M, Subramanian KL, Spielmann HP, Morris AJ. Efficient use of exogenous isoprenols for protein isoprenylation by MDA-MB-231 cells is regulated independently of the mevalonate pathway. J Biol Chem. 2013 Sep 20; 288(38):27444-27455. PMID: 23908355.
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    60. Singh S, Chang A, Helmich KE, Bingman CA, Wrobel RL, Beebe ET, Makino S, Aceti DJ, Dyer K, Hura GL, Sunkara M, Morris AJ, Phillips GN, Thorson JS. Structural and functional characterization of CalS11, a TDP-rhamnose 3'-O-methyltransferase involved in calicheamicin biosynthesis. ACS Chem Biol. 2013 Jul 19; 8(7):1632-9. PMID: 23662776.
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    61. Subramanian T, Subramanian KL, Sunkara M, Onono FO, Morris AJ, Spielmann HP. Syntheses of deuterium labeled prenyldiphosphate and prenylcysteine analogues for in vivo mass spectrometric quantification. J Labelled Comp Radiopharm. 2013 Jun 30; 56(8):370-5. PMID: 24285475.
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    62. Li X, Zhou Q, Sunkara M, Kutys ML, Wu Z, Rychahou P, Morris AJ, Zhu H, Evers BM, Huang C. Ubiquitylation of phosphatidylinositol 4-phosphate 5-kinase type I ? by HECTD1 regulates focal adhesion dynamics and cell migration. J Cell Sci. 2013 Jun 15; 126(Pt 12):2617-28. PMID: 23572508.
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    63. Morris AJ, Smyth SS. Lysophosphatidic acid and cardiovascular disease: seeing is believing. J Lipid Res. 2013 May; 54(5):1153-5. PMID: 23509404.
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    64. Kim C, Schneider G, Abdel-Latif A, Mierzejewska K, Sunkara M, Borkowska S, Ratajczak J, Morris AJ, Kucia M, Ratajczak MZ. Ceramide-1-phosphate regulates migration of multipotent stromal cells and endothelial progenitor cells--implications for tissue regeneration. Stem Cells. 2013 Mar; 31(3):500-10. PMID: 23193025.
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    65. Karapetyan AV, Klyachkin YM, Selim S, Sunkara M, Ziada KM, Cohen DA, Zuba-Surma EK, Ratajczak J, Smyth SS, Ratajczak MZ, Morris AJ, Abdel-Latif A. Bioactive lipids and cationic antimicrobial peptides as new potential regulators for trafficking of bone marrow-derived stem cells in patients with acute myocardial infarction. Stem Cells Dev. 2013 Jun 01; 22(11):1645-56. PMID: 23282236.
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    66. Xiang B, Zhang G, Ren H, Sunkara M, Morris AJ, Gartner TK, Smyth SS, Li Z. The P2Y(12) antagonists, 2MeSAMP and cangrelor, inhibit platelet activation through P2Y(12)/G(i)-dependent mechanism. PLoS One. 2012; 7(12):e51037. PMID: 23236426.
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    67. Panchatcharam M, Miriyala S, Salous A, Wheeler J, Dong A, Mueller P, Sunkara M, Escalante-Alcalde D, Morris AJ, Smyth SS. Lipid phosphate phosphatase 3 negatively regulates smooth muscle cell phenotypic modulation to limit intimal hyperplasia. Arterioscler Thromb Vasc Biol. 2013 Jan; 33(1):52-9. PMID: 23104851.
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    68. Mendoza A, Br?art B, Ramos-Perez WD, Pitt LA, Gobert M, Sunkara M, Lafaille JJ, Morris AJ, Schwab SR. The transporter Spns2 is required for secretion of lymph but not plasma sphingosine-1-phosphate. Cell Rep. 2012 Nov 29; 2(5):1104-10. PMID: 23103166.
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    69. Baker NA, Karounos M, English V, Fang J, Wei Y, Stromberg A, Sunkara M, Morris AJ, Swanson HI, Cassis LA. Coplanar polychlorinated biphenyls impair glucose homeostasis in lean C57BL/6 mice and mitigate beneficial effects of weight loss on glucose homeostasis in obese mice. Environ Health Perspect. 2013 Jan; 121(1):105-10. PMID: 23099484.
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    70. Deevska GM, Sunkara M, Morris AJ, Nikolova-Karakashian MN. Characterization of secretory sphingomyelinase activity, lipoprotein sphingolipid content and LDL aggregation in ldlr-/- mice fed on a high-fat diet. Biosci Rep. 2012 Oct; 32(5):479-90. PMID: 22712892.
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    71. Dong A, Sunkara M, Panchatcharam M, Salous A, Selim S, Morris AJ, Smyth SS. Synergistic effect of anemia and red blood cells transfusion on inflammation and lung injury. Adv Hematol. 2012; 2012:924042. PMID: 22919395.
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    72. Gellett AM, Kharel Y, Sunkara M, Morris AJ, Lynch KR. Biosynthesis of alkyl lysophosphatidic acid by diacylglycerol kinases. Biochem Biophys Res Commun. 2012 Jun 15; 422(4):758-63. PMID: 22627129.
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    73. S?nchez-S?nchez R, Morales-L?zaro SL, Baizabal JM, Sunkara M, Morris AJ, Escalante-Alcalde D. Lack of lipid phosphate phosphatase-3 in embryonic stem cells compromises neuronal differentiation and neurite outgrowth. Dev Dyn. 2012 May; 241(5):953-64. PMID: 22434721.
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    74. Liu J, Liang S, Liu X, Brown JA, Newman KE, Sunkara M, Morris AJ, Bhatnagar S, Li X, Pujol A, Graf GA. The absence of ABCD2 sensitizes mice to disruptions in lipid metabolism by dietary erucic acid. J Lipid Res. 2012 Jun; 53(6):1071-9. PMID: 22493092.
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    75. Federico L, Ren H, Mueller PA, Wu T, Liu S, Popovic J, Blalock EM, Sunkara M, Ovaa H, Albers HM, Mills GB, Morris AJ, Smyth SS. Autotaxin and its product lysophosphatidic acid suppress brown adipose differentiation and promote diet-induced obesity in mice. Mol Endocrinol. 2012 May; 26(5):786-97. PMID: 22474126.
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    76. Cantrell Stanford J, Morris AJ, Sunkara M, Popa GJ, Larson KL, ?zcan S. Sphingosine 1-phosphate (S1P) regulates glucose-stimulated insulin secretion in pancreatic beta cells. J Biol Chem. 2012 Apr 13; 287(16):13457-64. PMID: 22389505.
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    77. Zaytseva YY, Rychahou PG, Gulhati P, Elliott VA, Mustain WC, O'Connor K, Morris AJ, Sunkara M, Weiss HL, Lee EY, Evers BM. Inhibition of fatty acid synthase attenuates CD44-associated signaling and reduces metastasis in colorectal cancer. Cancer Res. 2012 Mar 15; 72(6):1504-17. PMID: 22266115.
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    78. Sumanasekera C, Kelemen O, Beullens M, Aubol BE, Adams JA, Sunkara M, Morris A, Bollen M, Andreadis A, Stamm S. C6 pyridinium ceramide influences alternative pre-mRNA splicing by inhibiting protein phosphatase-1. Nucleic Acids Res. 2012 May; 40(9):4025-39. PMID: 22210893.
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    79. Selim S, Sunkara M, Salous AK, Leung SW, Berdyshev EV, Bailey A, Campbell CL, Charnigo R, Morris AJ, Smyth SS. Plasma levels of sphingosine 1-phosphate are strongly correlated with haematocrit, but variably restored by red blood cell transfusions. Clin Sci (Lond). 2011 Dec; 121(12):565-72. PMID: 21749329.
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    80. Wu Z, Li X, Sunkara M, Spearman H, Morris AJ, Huang C. PIPKI? regulates focal adhesion dynamics and colon cancer cell invasion. PLoS One. 2011; 6(9):e24775. PMID: 21931851.
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    81. Fulkerson Z, Wu T, Sunkara M, Kooi CV, Morris AJ, Smyth SS. Binding of autotaxin to integrins localizes lysophosphatidic acid production to platelets and mammalian cells. J Biol Chem. 2011 Oct 07; 286(40):34654-63. PMID: 21832043.
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    82. Zheng Y, Morris A, Sunkara M, Layne J, Toborek M, Hennig B. Epigallocatechin-gallate stimulates NF-E2-related factor and heme oxygenase-1 via caveolin-1 displacement. J Nutr Biochem. 2012 Feb; 23(2):163-8. PMID: 21447442.
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    83. L?pez-Ju?rez A, Morales-L?zaro S, S?nchez-S?nchez R, Sunkara M, Lomel? H, Velasco I, Morris AJ, Escalante-Alcalde D. Expression of LPP3 in Bergmann glia is required for proper cerebellar sphingosine-1-phosphate metabolism/signaling and development. Glia. 2011 Apr; 59(4):577-89. PMID: 21319224.
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    84. Majkova Z, Layne J, Sunkara M, Morris AJ, Toborek M, Hennig B. Omega-3 fatty acid oxidation products prevent vascular endothelial cell activation by coplanar polychlorinated biphenyls. Toxicol Appl Pharmacol. 2011 Feb 15; 251(1):41-9. PMID: 21130106.
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    85. Ren H, Federico L, Huang H, Sunkara M, Drennan T, Frohman MA, Smyth SS, Morris AJ. A phosphatidic acid binding/nuclear localization motif determines lipin1 function in lipid metabolism and adipogenesis. Mol Biol Cell. 2010 Sep 15; 21(18):3171-81. PMID: 20660155.
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    86. Mathews TP, Kennedy AJ, Kharel Y, Kennedy PC, Nicoara O, Sunkara M, Morris AJ, Wamhoff BR, Lynch KR, Macdonald TL. Discovery, biological evaluation, and structure-activity relationship of amidine based sphingosine kinase inhibitors. J Med Chem. 2010 Apr 08; 53(7):2766-78. PMID: 20205392.
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    87. Albers HM, Dong A, van Meeteren LA, Egan DA, Sunkara M, van Tilburg EW, Schuurman K, van Tellingen O, Morris AJ, Smyth SS, Moolenaar WH, Ovaa H. Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation. Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16):7257-62. PMID: 20360563.
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    88. Boyanovsky BB, Li X, Shridas P, Sunkara M, Morris AJ, Webb NR. Bioactive products generated by group V sPLA(2) hydrolysis of LDL activate macrophages to secrete pro-inflammatory cytokines. Cytokine. 2010 Apr; 50(1):50-7. PMID: 20138782.
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    89. Miriyala S, Subramanian T, Panchatcharam M, Ren H, McDermott MI, Sunkara M, Drennan T, Smyth SS, Spielmann HP, Morris AJ. Functional characterization of the atypical integral membrane lipid phosphatase PDP1/PPAPDC2 identifies a pathway for interconversion of isoprenols and isoprenoid phosphates in mammalian cells. J Biol Chem. 2010 Apr 30; 285(18):13918-29. PMID: 20110354.
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    90. Smyth SS, Cheng HY, Miriyala S, Panchatcharam M, Morris AJ. Roles of lysophosphatidic acid in cardiovascular physiology and disease. Biochim Biophys Acta. 2008 Sep; 1781(9):563-70. PMID: 18586114.
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    91. Luquain C, Singh A, Wang L, Natarajan V, Morris AJ. Role of phospholipase D in agonist-stimulated lysophosphatidic acid synthesis by ovarian cancer cells. J Lipid Res. 2003 Oct; 44(10):1963-75. PMID: 12837850.
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