 Spleen
"Spleen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
No definition found.
| Descriptor ID |
D013154
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| MeSH Number(s) |
A10.549.700 A15.382.520.604.700
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Spleen".
Below are MeSH descriptors whose meaning is more specific than "Spleen".
This graph shows the total number of publications written about "Spleen" by people in UAMS Profiles by year, and whether "Spleen" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2024 | 1 | 1 | 2 | | 2023 | 0 | 1 | 1 | | 2022 | 0 | 2 | 2 | | 2021 | 2 | 1 | 3 | | 2020 | 1 | 2 | 3 | | 2019 | 2 | 0 | 2 | | 2018 | 2 | 0 | 2 | | 2017 | 2 | 3 | 5 | | 2016 | 4 | 5 | 9 | | 2015 | 2 | 5 | 7 | | 2014 | 1 | 2 | 3 | | 2013 | 0 | 1 | 1 | | 2012 | 1 | 4 | 5 | | 2011 | 1 | 1 | 2 | | 2010 | 2 | 3 | 5 | | 2009 | 2 | 4 | 6 | | 2008 | 7 | 4 | 11 | | 2007 | 2 | 2 | 4 | | 2006 | 0 | 3 | 3 | | 2005 | 1 | 3 | 4 | | 2004 | 1 | 7 | 8 | | 2003 | 0 | 3 | 3 | | 2002 | 0 | 2 | 2 | | 2001 | 0 | 3 | 3 | | 2000 | 0 | 4 | 4 | | 1999 | 0 | 2 | 2 | | 1996 | 2 | 1 | 3 | | 1995 | 1 | 0 | 1 | | 1993 | 1 | 0 | 1 | | 1992 | 2 | 1 | 3 | | 1991 | 1 | 1 | 2 | | 1990 | 0 | 6 | 6 | | 1989 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Spleen" by people in Profiles over the past ten years.
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Ghimire L, Paudel S, Le J, Jin L, Cai S, Bhattarai D, Jeyaseelan S. NLRP6 negatively regulates host defense against polymicrobial sepsis. Front Immunol. 2024; 15:1248907.
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Naiditch JA, Notrica DM, Sayrs LW, Linnaus M, Stottlemyre R, Garcia NM, Lawson KA, Cohen AS, Letton RW, Johnson J, Maxson RT, Eubanks JW, Ryan M, Alder A, Ponsky TA, St Peter SD, Bhatia AM, Leys CM. The use and timing of angioembolization in pediatric blunt liver and spleen injury. J Trauma Acute Care Surg. 2024 Jun 01; 96(6):915-920.
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Reynolds ES, Wooldridge JT, Stevenson HL, Thangamani S. The Lone Star tick, Amblyomma americanum, salivary factors exacerbate the clinical outcome of Heartland virus disease in a small animal model. Sci Rep. 2023 08 16; 13(1):13304.
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Cui SG, Zhang YL, Guo HW, Zhou BH, Tian EJ, Zhao J, Lin L, Wang HW. Molybdenum-Induced Apoptosis of Splenocytes and Thymocytes and Changes of Peripheral Blood in Sheep. Biol Trace Elem Res. 2023 Sep; 201(9):4389-4399.
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Kraus S, Klassen P, Kircher M, Dierks A, Habringer S, G?ble A, Kort?m KM, Weinhold N, Ademaj-Kospiri V, Werner RA, Schirbel A, Buck AK, Herhaus P, Wester HJ, Rosenwald A, Weber WA, Einsele H, Keller U, Rasche L, Lapa C. Reduced splenic uptake on 68Ga-Pentixafor-PET/CT imaging in multiple myeloma - a potential imaging biomarker for disease prognosis. Theranostics. 2022; 12(13):5986-5994.
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O'Neal KA, Latham LE, Ntirandekura E, Foscue CL, Stumhofer JS. ICOS Expression Is Required for Maintenance but Not the Formation of Germinal Centers in the Spleen in Response to Plasmodium yoelii Infection. Infect Immun. 2022 03 17; 90(3):e0046821.
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Kingsbury C, Shear A, Heyck M, Sadanandan N, Zhang H, Gonzales-Portillo B, Cozene B, Sheyner M, Navarro-Torres L, Garc?a-S?nchez J, Lee JY, Borlongan CV. Inflammation-relevant microbiome signature of the stroke brain, gut, spleen, and thymus and the impact of exercise. J Cereb Blood Flow Metab. 2021 12; 41(12):3200-3212.
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Wolfe AR, Siedow M, Nalin A, DiCostanzo D, Miller ED, Diaz DA, Arnett A, Cloyd JM, Dillhoff M, Ejaz A, Tsung A, Williams TM. Increasing neutrophil-to-lymphocyte ratio following radiation is a poor prognostic factor and directly correlates with splenic radiation dose in pancreatic cancer. Radiother Oncol. 2021 05; 158:207-214.
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Ghosh D, Stumhofer JS. The spleen: "epicenter" in malaria infection and immunity. J Leukoc Biol. 2021 10; 110(4):753-769.
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Sadhukhan R, Majumdar D, Garg S, Landes RD, McHargue V, Pawar SA, Chowdhury P, Griffin RJ, Narayanasamy G, Boerma M, Dobretsov M, Hauer-Jensen M, Pathak R. Simultaneous exposure to chronic irradiation and simulated microgravity differentially alters immune cell phenotype in mouse thymus and spleen. Life Sci Space Res (Amst). 2021 Feb; 28:66-73.
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He Y, Koch R, Budamagunta V, Zhang P, Zhang X, Khan S, Thummuri D, Ortiz YT, Zhang X, Lv D, Wiegand JS, Li W, Palmer AC, Zheng G, Weinstock DM, Zhou D. DT2216-a Bcl-xL-specific degrader is highly active against Bcl-xL-dependent T cell lymphomas. J Hematol Oncol. 2020 07 16; 13(1):95.
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Johnson P, Wong K, Chen Z, Bercu ZL, Newsome J, West DL, Dariushnia S, Findeiss LK, Kokabi N. Meta-analysis of Intraprocedural Comparative Effectiveness of Vascular Plugs Vs Coils in Proximal Splenic Artery Embolization and Associated Patient Radiation Exposure. Curr Probl Diagn Radiol. 2021 Sep-Oct; 50(5):623-628.
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Renno A, Hill M, Abdel-Aziz Y, Meawad H, Lenhard A, Nawras A. Diagnosis of intrapancreatic accessory spleen by endoscopic ultrasound-guided fine-needle aspiration mimicking a pancreatic neoplasm: a case report and review of literature. Clin J Gastroenterol. 2020 Apr; 13(2):287-297.
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Svahn SL, Guti?rrez S, Ulleryd MA, Nookaew I, Osla V, Beckman F, Nilsson S, Karlsson A, Jansson JO, Johansson ME. Dietary Polyunsaturated Fatty Acids Promote Neutrophil Accumulation in the Spleen by Altering Chemotaxis and Delaying Cell Death. Infect Immun. 2019 08; 87(8).
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Rasche L, Kumar M, Gershner G, Samant R, Van Hemert R, Heidemeier A, Lapa C, Bley T, Buck A, McDonald J, Hillengass J, Epstein J, Thanendrarajan S, Schinke C, van Rhee F, Zangari M, Barlogie B, Davies FE, Morgan GJ, Weinhold N. Lack of Spleen Signal on Diffusion Weighted MRI is associated with High Tumor Burden and Poor Prognosis in Multiple Myeloma: A Link to Extramedullary Hematopoiesis? Theranostics. 2019; 9(16):4756-4763.
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Fertan E, Rodrigues GJ, Wheeler RV, Goguen D, Wong AA, James H, Stadnyk A, Brown RE, Weaver ICG. Cognitive Decline, Cerebral-Spleen Tryptophan Metabolism, Oxidative Stress, Cytokine Production, and Regulation of the Txnip Gene in a Triple Transgenic Mouse Model of Alzheimer Disease. Am J Pathol. 2019 07; 189(7):1435-1450.
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Gust KA, Chaitankar V, Ghosh P, Wilbanks MS, Chen X, Barker ND, Pham D, Scanlan LD, Rawat A, Talent LG, Quinn MJ, Vulpe CD, Elasri MO, Johnson MS, Perkins EJ, McFarland CA. Multiple environmental stressors induce complex transcriptomic responses indicative of phenotypic outcomes in Western fence lizard. BMC Genomics. 2018 Dec 05; 19(1):877.
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Cheema AK, Byrum SD, Sharma NK, Altadill T, Kumar VP, Biswas S, Balgley BM, Hauer-Jensen M, Tackett AJ, Ghosh SP. Proteomic Changes in Mouse Spleen after Radiation-Induced Injury and its Modulation by Gamma-Tocotrienol. Radiat Res. 2018 11; 190(5):449-463.
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Booth BJ, Bowman SM, Escobar MA, Sharar SR. Long-term sustainability of Washington State's quality improvement initiative for the management of pediatric spleen injuries. J Pediatr Surg. 2018 Nov; 53(11):2209-2213.
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Setter DO, Runge EM, Schartz ND, Kennedy FM, Brown BL, McMillan KP, Miller WM, Shah KM, Haulcomb MM, Sanders VM, Jones KJ. Impact of peripheral immune status on central molecular responses to facial nerve axotomy. Brain Behav Immun. 2018 02; 68:98-110.
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Johnsen NV, Betzold RD, Guillamondegui OD, Dennis BM, Stassen NA, Bhullar I, Ibrahim JA. Surgical Management of Solid Organ Injuries. Surg Clin North Am. 2017 Oct; 97(5):1077-1105.
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Ghosh D, Brown SL, Stumhofer JS. IL-17 Promotes Differentiation of Splenic LSK- Lymphoid Progenitors into B Cells following Plasmodium yoelii Infection. J Immunol. 2017 09 01; 199(5):1783-1795.
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Jabbour G, Al-Hassani A, El-Menyar A, Abdelrahman H, Peralta R, Ellabib M, Al-Jogol H, Asim M, Al-Thani H. Clinical and Radiological Presentations and Management of Blunt Splenic Trauma: A Single Tertiary Hospital Experience. Med Sci Monit. 2017 Jul 12; 23:3383-3392.
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Kaur H, Muhleman M, Balon HR. Spleen Uptake on a Bone Scan. J Nucl Med Technol. 2017 Sep; 45(3):245-246.
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Cox TM, Drelichman G, Cravo R, Balwani M, Burrow TA, Martins AM, Lukina E, Rosenbloom B, Goker-Alpan O, Watman N, El-Beshlawy A, Kishnani PS, Pedroso ML, Gaemers SJM, Tayag R, Peterschmitt MJ. Eliglustat maintains long-term clinical stability in patients with Gaucher disease type 1 stabilized on enzyme therapy. Blood. 2017 04 27; 129(17):2375-2383.
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Soni NK, Ross AB, Scheers N, Savolainen OI, Nookaew I, Gabrielsson BG, Sandberg AS. Splenic Immune Response Is Down-Regulated in C57BL/6J Mice Fed Eicosapentaenoic Acid and Docosahexaenoic Acid Enriched High Fat Diet. Nutrients. 2017 Jan 10; 9(1).
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Koturbash I, Merrifield M, Kovalchuk O. Fractionated exposure to low doses of ionizing radiation results in accumulation of DNA damage in mouse spleen tissue and activation of apoptosis in a p53/Atm-independent manner. Int J Radiat Biol. 2017 02; 93(2):148-155.
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Khan S, George N, Tharian B. Extraluminal migration of an esophageal metal stent causing splenic injury. Endoscopy. 2016 0; 48(S 01):E326.
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Ortiz-Miranda S, Ji R, Jurczyk A, Aryee KE, Mo S, Fletcher T, Shaffer SA, Greiner DL, Bortell R, Gregg RG, Cheng A, Hennings LJ, Rittenhouse AR. A novel transgenic mouse model of lysosomal storage disorder. Am J Physiol Gastrointest Liver Physiol. 2016 11 01; 311(5):G903-G919.
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Li LX, Benoun JM, Weiskopf K, Garcia KC, McSorley SJ. Salmonella Infection Enhances Erythropoietin Production by the Kidney and Liver, Which Correlates with Elevated Bacterial Burdens. Infect Immun. 2016 10; 84(10):2833-41.
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Gilbert KM, Blossom SJ, Erickson SW, Broadfoot B, West K, Bai S, Li J, Cooney CA. Chronic exposure to trichloroethylene increases DNA methylation of the Ifng promoter in CD4+ T cells. Toxicol Lett. 2016 Oct 17; 260:1-7.
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Ghosh D, Wikenheiser DJ, Kennedy B, McGovern KE, Stuart JD, Wilson EH, Stumhofer JS. An Atypical Splenic B Cell Progenitor Population Supports Antibody Production during Plasmodium Infection in Mice. J Immunol. 2016 09 01; 197(5):1788-800.
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van der Meer AJ, Maan R, Veldt BJ, Feld JJ, Wedemeyer H, Dufour JF, Lammert F, Duarte-Rojo A, Manns MP, Zeuzem S, Hofmann WP, de Knegt RJ, Hansen BE, Janssen HL. Improvement of platelets after SVR among patients with chronic HCV infection and advanced hepatic fibrosis. J Gastroenterol Hepatol. 2016 Jun; 31(6):1168-76.
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Svahn SL, V?remo L, Gabrielsson BG, Peris E, Nookaew I, Grahnemo L, Sandberg AS, Wernstedt Asterholm I, Jansson JO, Nielsen J, Johansson ME. Six Tissue Transcriptomics Reveals Specific Immune Suppression in Spleen by Dietary Polyunsaturated Fatty Acids. PLoS One. 2016; 11(5):e0155099.
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Ghosh SP, Pathak R, Kumar P, Biswas S, Bhattacharyya S, Kumar VP, Hauer-Jensen M, Biswas R. Gamma-Tocotrienol Modulates Radiation-Induced MicroRNA Expression in Mouse Spleen. Radiat Res. 2016 05; 185(5):485-95.
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Larsen CP, Beggs ML, Wilson JD, Lathrop SL. Prevalence and organ distribution of leukocyte chemotactic factor 2 amyloidosis (ALECT2) among decedents in New Mexico. Amyloid. 2016 Jun; 23(2):119-23.
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Maltez VI, Tubbs AL, Cook KD, Aachoui Y, Falcone EL, Holland SM, Whitmire JK, Miao EA. Inflammasomes Coordinate Pyroptosis and Natural Killer Cell Cytotoxicity to Clear Infection by a Ubiquitous Environmental Bacterium. Immunity. 2015 Nov 17; 43(5):987-97.
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Chepelev NL, Long AS, Williams A, Kuo B, Gagn? R, Kennedy DA, Phillips DH, Arlt VM, White PA, Yauk CL. Transcriptional Profiling of Dibenzo[def,p]chrysene-induced Spleen Atrophy Provides Mechanistic Insights into its Immunotoxicity in MutaMouse. Toxicol Sci. 2016 Jan; 149(1):251-68.
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Notrica DM, Eubanks JW, Tuggle DW, Maxson RT, Letton RW, Garcia NM, Alder AC, Lawson KA, St Peter SD, Megison S, Garcia-Filion P. Nonoperative management of blunt liver and spleen injury in children: Evaluation of the ATOMAC guideline using GRADE. J Trauma Acute Care Surg. 2015 Oct; 79(4):683-93.
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El-Matbouly M, Jabbour G, El-Menyar A, Peralta R, Abdelrahman H, Zarour A, Al-Hassani A, Al-Thani H. Blunt splenic trauma: Assessment, management and outcomes. Surgeon. 2016 Feb; 14(1):52-8.
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Noda A, Suemori H, Hirai Y, Hamasaki K, Kodama Y, Mitani H, Landes RD, Nakamura N. Creation of Mice Bearing a Partial Duplication of HPRT Gene Marked with a GFP Gene and Detection of Revertant Cells In Situ as GFP-Positive Somatic Cells. PLoS One. 2015; 10(8):e0136041.
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Liu S, Bowman SM, Smith TC, Sharar SR. Trends in pediatric spleen management: Do hospital type and ownership still matter? J Trauma Acute Care Surg. 2015 May; 78(5):935-42.
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Cieniewicz B, Dong Q, Li G, Forrest JC, Mounce BC, Tarakanova VL, van der Velden A, Krug LT. Murine Gammaherpesvirus 68 Pathogenesis Is Independent of Caspase-1 and Caspase-11 in Mice and Impairs Interleukin-1? Production upon Extrinsic Stimulation in Culture. J Virol. 2015 Jul; 89(13):6562-74.
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Cox TM, Drelichman G, Cravo R, Balwani M, Burrow TA, Martins AM, Lukina E, Rosenbloom B, Ross L, Angell J, Puga AC. Eliglustat compared with imiglucerase in patients with Gaucher's disease type 1 stabilised on enzyme replacement therapy: a phase 3, randomised, open-label, non-inferiority trial. Lancet. 2015 Jun 13; 385(9985):2355-62.
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Scindia Y, Dey P, Thirunagari A, Liping H, Rosin DL, Floris M, Okusa MD, Swaminathan S. Hepcidin Mitigates Renal Ischemia-Reperfusion Injury by Modulating Systemic Iron Homeostasis. J Am Soc Nephrol. 2015 Nov; 26(11):2800-14.
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Kovalchuk IP, Golubov A, Koturbash IV, Kutanzi K, Martin OA, Kovalchuk O. Age-dependent changes in DNA repair in radiation-exposed mice. Radiat Res. 2014 Dec; 182(6):683-94.
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