Cathepsin B
"Cathepsin B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A lysosomal cysteine proteinase with a specificity similar to that of PAPAIN. The enzyme is present in a variety of tissues and is important in many physiological and pathological processes. In pathology, cathepsin B has been found to be involved in DEMYELINATION; EMPHYSEMA; RHEUMATOID ARTHRITIS, and NEOPLASM INVASIVENESS.
| Descriptor ID |
D002401
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| MeSH Number(s) |
D08.811.277.656.224.125 D08.811.277.656.262.500.133 D08.811.277.656.300.200.133
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cathepsin B".
Below are MeSH descriptors whose meaning is more specific than "Cathepsin B".
This graph shows the total number of publications written about "Cathepsin B" by people in UAMS Profiles by year, and whether "Cathepsin B" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2009 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cathepsin B" by people in Profiles over the past ten years.
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Zhang X, Tang K, Wang H, Liu Y, Bao B, Fang Y, Zhang X, Lu W. Design, Synthesis, and Biological Evaluation of New Cathepsin B-Sensitive Camptothecin Nanoparticles Equipped with a Novel Multifuctional Linker. Bioconjug Chem. 2016 05 18; 27(5):1267-75.
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Gu YH, Kanazawa M, Hung SY, Wang X, Fukuda S, Koziol JA, Del Zoppo GJ. Cathepsin L acutely alters microvessel integrity within the neurovascular unit during focal cerebral ischemia. J Cereb Blood Flow Metab. 2015 Nov; 35(11):1888-900.