 Chimera
"Chimera" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An individual that contains cell populations derived from different zygotes.
| Descriptor ID |
D002678
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| MeSH Number(s) |
B01.050.050.530 B01.650.085 B05.200
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Chimera".
Below are MeSH descriptors whose meaning is more specific than "Chimera".
This graph shows the total number of publications written about "Chimera" by people in UAMS Profiles by year, and whether "Chimera" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 1 | 1 | 2 | | 2021 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 | | 2016 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1990 | 1 | 0 | 1 |
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Below are the most recent publications written about "Chimera" by people in Profiles over the past ten years.
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Li D, Yu X, Kottur J, Gong W, Zhang Z, Storey AJ, Tsai YH, Uryu H, Shen Y, Byrum SD, Edmondson RD, Mackintosh SG, Cai L, Liu Z, Aggarwal AK, Tackett AJ, Liu J, Jin J, Wang GG. Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic. Oncogene. 2022 Jun; 41(24):3328-3340.
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Khan S, Wiegand J, Zhang P, Hu W, Thummuri D, Budamagunta V, Hua N, Jin L, Allegra CJ, Kopetz SE, Zajac-Kaye M, Kaye FJ, Zheng G, Zhou D. BCL-XL PROTAC degrader DT2216 synergizes with sotorasib in preclinical models of KRASG12C-mutated cancers. J Hematol Oncol. 2022 03 09; 15(1):23.
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Xu C, Meng F, Park KS, Storey AJ, Gong W, Tsai YH, Gibson E, Byrum SD, Li D, Edmondson RD, Mackintosh SG, Vedadi M, Cai L, Tackett AJ, Kaniskan HÜ, Jin J, Wang GG. A NSD3-targeted PROTAC suppresses NSD3 and cMyc oncogenic nodes in cancer cells. Cell Chem Biol. 2022 03 17; 29(3):386-397.e9.
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Liu X, Zhang X, Lv D, Yuan Y, Zheng G, Zhou D. Assays and technologies for developing proteolysis targeting chimera degraders. Future Med Chem. 2020 06; 12(12):1155-1179.
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Kaffenberger BH, Zhang E, Duncan JR, Jaglowski S, Klisovic RB, Devine SM, Wong HK, Gru AA. Endothelial chimerism in chronic sclerotic-type chronic graft-versus-host disease (GVHD) and GVHD-associated angiomatosis. Br J Dermatol. 2016 Oct; 175(4):782-4.
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Grosswendt S, Filipchyk A, Manzano M, Klironomos F, Schilling M, Herzog M, Gottwein E, Rajewsky N. Unambiguous identification of miRNA:target site interactions by different types of ligation reactions. Mol Cell. 2014 Jun 19; 54(6):1042-1054.
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