 Biotin
"Biotin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A water-soluble, enzyme co-factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk.
| Descriptor ID |
D001710
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| MeSH Number(s) |
D03.383.129.308.080 D08.211.096
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| Concept/Terms |
Biotin- Biotin
- Vitamin H
- H, Vitamin
Biokur- Biokur
- Biocur Brand of Biotin
- Biotin Biocur Brand
Biotin Gelfert- Biotin Gelfert
- Gelfert, Biotin
- Ziethen Brand of Biotin
- Biotin Ziethen Brand
Biotin Hermes- Biotin Hermes
- Hermes, Biotin
- Hermes Brand of Biotin
- Biotin Hermes Brand
Biotin-ratiopharm- Biotin-ratiopharm
- Biotin ratiopharm
- Biotinratiopharm
- ratiopharm Brand of Biotin
- Biotin ratiopharm Brand
Rombellin- Rombellin
- Simons Brand of Biotin
- Biotin Simons Brand
Deacura- Deacura
- Dermapharm Brand of Biotin
- Biotin Dermapharm Brand
Gabunat- Gabunat
- Strathmann Brand of Biotin
- Biotin Strathmann Brand
Medebiotin- Medebiotin
- Medea Brand of Biotin Sodium Salt
medobiotin- medobiotin
- Medopharm Brand of Biotin
- Biotin Medopharm Brand
Biotine Roche- Biotine Roche
- Roche, Biotine
- Roche Brand of Biotin
- Biotin Roche Brand
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Below are MeSH descriptors whose meaning is more general than "Biotin".
Below are MeSH descriptors whose meaning is more specific than "Biotin".
This graph shows the total number of publications written about "Biotin" by people in UAMS Profiles by year, and whether "Biotin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 0 | 1 | 1 | | 2017 | 3 | 0 | 3 | | 2016 | 1 | 0 | 1 | | 2015 | 2 | 0 | 2 | | 2014 | 3 | 0 | 3 | | 2013 | 2 | 0 | 2 | | 2012 | 2 | 0 | 2 | | 2011 | 6 | 0 | 6 | | 2010 | 6 | 0 | 6 | | 2008 | 6 | 1 | 7 | | 2007 | 0 | 1 | 1 | | 2006 | 1 | 1 | 2 | | 2005 | 5 | 0 | 5 | | 2004 | 5 | 0 | 5 | | 2003 | 2 | 0 | 2 | | 2002 | 5 | 1 | 6 | | 2001 | 5 | 0 | 5 | | 2000 | 2 | 1 | 3 | | 1999 | 8 | 0 | 8 | | 1998 | 2 | 0 | 2 | | 1997 | 13 | 1 | 14 | | 1996 | 1 | 2 | 3 | | 1995 | 1 | 1 | 2 | | 1994 | 2 | 0 | 2 | | 1993 | 2 | 2 | 4 | | 1992 | 4 | 0 | 4 | | 1991 | 1 | 0 | 1 | | 1990 | 6 | 2 | 8 | | 1989 | 3 | 3 | 6 | | 1988 | 5 | 3 | 8 | | 1987 | 2 | 2 | 4 | | 1986 | 3 | 0 | 3 | | 1985 | 3 | 1 | 4 |
To return to the timeline, click here.
Below are the most recent publications written about "Biotin" by people in Profiles over the past ten years.
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Obeidat M, McConnell KA, Li X, Bui B, Stathakis S, Papanikolaou N, Rasmussen K, Ha CS, Lee SE, Shim EY, Kirby N. DNA double-strand breaks as a method of radiation measurements for therapeutic beams. Med Phys. 2018 Jul; 45(7):3460-3465.
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Mock DM. Biotin: From Nutrition to Therapeutics. J Nutr. 2017 08; 147(8):1487-1492.
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Schmidt RL, Mock DM, Franco RS, Cohen RM, North AK, Cancelas JA, Geisen C, Strauss RG, Vlaar AP, Nalbant D, Widness JA. Antibodies to biotinylated red blood cells in adults and infants: improved detection, partial characterization, and dependence on red blood cell-biotin dose. Transfusion. 2017 06; 57(6):1488-1496.
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Kuruvilla DJ, Widness JA, Nalbant D, Schmidt RL, Mock DM, An G, Veng-Pedersen P. Estimation of adult and neonatal RBC lifespans in anemic neonates using RBCs labeled at several discrete biotin densities. Pediatr Res. 2017 Jun; 81(6):905-910.
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Peyro Saint Paul L, Debruyne D, Bernard D, Mock DM, Defer GL. Pharmacokinetics and pharmacodynamics of MD1003 (high-dose biotin) in the treatment of progressive multiple sclerosis. Expert Opin Drug Metab Toxicol. 2016; 12(3):327-44.
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Widness JA, Kuruvilla DJ, Mock DM, Matthews NI, Nalbant D, Cress GA, Schmidt RL, Strauss RG, Zimmerman MB, Veng-Pedersen P. Autologous Infant and Allogeneic Adult Red Cells Demonstrate Similar Concurrent Post-Transfusion Survival in Very Low Birth Weight Neonates. J Pediatr. 2015 Nov; 167(5):1001-6.
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Sedel F, Bernard D, Mock DM, Tourbah A. Targeting demyelination and virtual hypoxia with high-dose biotin as a treatment for progressive multiple sclerosis. Neuropharmacology. 2016 Nov; 110(Pt B):644-653.
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Bogusiewicz A, Boysen G, Mock DM. In HepG2 cells, coexisting carnitine deficiency masks important indicators of marginal biotin deficiency. J Nutr. 2015 Jan; 145(1):32-40.
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Mock DM. Adequate intake of biotin in pregnancy: why bother? J Nutr. 2014 Dec; 144(12):1885-6.
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Mock DM, Widness JA, Veng-Pedersen P, Strauss RG, Cancelas JA, Cohen RM, Lindsell CJ, Franco RS. Measurement of posttransfusion red cell survival with the biotin label. Transfus Med Rev. 2014 Jul; 28(3):114-25.
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Widness JA, Nalbant D, Matthews NI, Strauss RG, Schmidt RL, Cress GA, Zimmerman MB, Mock DM. Tracking donor RBC survival in premature infants: agreement of multiple populations of biotin-labeled RBCs with Kidd antigen-mismatched RBCs. Pediatr Res. 2013 Dec; 74(6):689-97.
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Jana B, Mondal G, Biswas A, Chakraborty I, Saha A, Kurkute P, Ghosh S. Dual functionalized graphene oxide serves as a carrier for delivering oligohistidine- and biotin-tagged biomolecules into cells. Macromol Biosci. 2013 Nov; 13(11):1478-84.
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Bogusiewicz A, Horvath TD, Stratton SL, Mock DM, Boysen G. Measurement of acylcarnitine substrate to product ratios specific to biotin-dependent carboxylases offers a combination of indicators of biotin status in humans. J Nutr. 2012 Sep; 142(9):1621-5.
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Mock DM, Matthews NI, Zhu S, Strauss RG, Schmidt RL, Zimmerman MB, Nalbant D, Freise KJ, Saleh M, Veng-Pedersen P, Widness JA. Comparison of red blood cell survival in sheep determined using red blood cells labeled with either biotin at multiple densities or [14C]cyanate: validation of a model to study human physiology and disease. Transfusion. 2012 May; 52(5):963-73.
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Stratton SL, Henrich CL, Matthews NI, Bogusiewicz A, Dawson AM, Horvath TD, Owen SN, Boysen G, Moran JH, Mock DM. Marginal biotin deficiency can be induced experimentally in humans using a cost-effective outpatient design. J Nutr. 2012 Jan; 142(1):22-6.
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Mock DM, Lankford GL, Matthews NI, Burmeister LF, Kahn D, Widness JA, Strauss RG. Accelerated removal of antibody-coated red blood cells from the circulation is accurately tracked by a biotin label. Transfusion. 2012 May; 52(5):1097-105.
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Mock DM, Stratton SL, Horvath TD, Bogusiewicz A, Matthews NI, Henrich CL, Dawson AM, Spencer HJ, Owen SN, Boysen G, Moran JH. Urinary excretion of 3-hydroxyisovaleric acid and 3-hydroxyisovaleryl carnitine increases in response to a leucine challenge in marginally biotin-deficient humans. J Nutr. 2011 Nov; 141(11):1925-30.
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Horvath TD, Matthews NI, Stratton SL, Mock DM, Boysen G. Measurement of 3-hydroxyisovaleric acid in urine from marginally biotin-deficient humans by UPLC-MS/MS. Anal Bioanal Chem. 2011 Nov; 401(9):2805-10.
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Stratton SL, Horvath TD, Bogusiewicz A, Matthews NI, Henrich CL, Spencer HJ, Moran JH, Mock DM. Urinary excretion of 3-hydroxyisovaleryl carnitine is an early and sensitive indicator of marginal biotin deficiency in humans. J Nutr. 2011 Mar; 141(3):353-8.
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Mock DM, Matthews NI, Zhu S, Burmeister LF, Zimmerman MB, Strauss RG, Schmidt RL, Nalbant D, Cress GA, Widness JA. Red blood cell (RBC) volume can be independently determined in vivo in humans using RBCs labeled at different densities of biotin. Transfusion. 2011 Jan; 51(1):148-57.
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Mock DM, Matthews NI, Zhu S, Burmeister LF, Zimmerman MB, Strauss RG, Schmidt RL, Nalbant D, Freise KJ, Veng-Pedersen P, Widness JA. Red blood cell (RBC) volume can be independently determined in vivo in the sheep using ovine RBCs labeled at different densities of biotin. Transfusion. 2010 Dec; 50(12):2553-64.
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Mock DM, Matthews NI, Zhu S, Strauss RG, Schmidt RL, Nalbant D, Cress GA, Widness JA. Red blood cell (RBC) survival determined in humans using RBCs labeled at multiple biotin densities. Transfusion. 2011 May; 51(5):1047-57.
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Horvath TD, Stratton SL, Bogusiewicz A, Owen SN, Mock DM, Moran JH. Quantitative measurement of urinary excretion of 3-hydroxyisovaleryl carnitine by LC-MS/MS as an indicator of biotin status in humans. Anal Chem. 2010 Nov 15; 82(22):9543-8.
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Pindolia K, Jordan M, Guo C, Matthews N, Mock DM, Strovel E, Blitzer M, Wolf B. Development and characterization of a mouse with profound biotinidase deficiency: a biotin-responsive neurocutaneous disorder. Mol Genet Metab. 2011 Feb; 102(2):161-9.
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Stratton SL, Horvath TD, Bogusiewicz A, Matthews NI, Henrich CL, Spencer HJ, Moran JH, Mock DM. Plasma concentration of 3-hydroxyisovaleryl carnitine is an early and sensitive indicator of marginal biotin deficiency in humans. Am J Clin Nutr. 2010 Dec; 92(6):1399-405.
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Horvath TD, Stratton SL, Bogusiewicz A, Pack L, Moran J, Mock DM. Quantitative measurement of plasma 3-hydroxyisovaleryl carnitine by LC-MS/MS as a novel biomarker of biotin status in humans. Anal Chem. 2010 May 15; 82(10):4140-4.
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