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Youssef Aachoui

TitleAssistant Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentMicrobiology And Immunology, College of Medicine
Address506G BIOMED
4301 W. Markham
Mail Slot # 511
Little Rock AR 72205
ORCID ORCID Icon0000-0003-0878-5511 Additional info
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    Collapse Research 
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    R21AI175731     (AACHOUI, YOUSSEF)Aug 25, 2023 - Jul 31, 2025
    NIH/Nat. Inst. of Allergy & Infectious Diseases
    Pyroptotic Macrophages Traps Against Shigella Infection
    Role: Principal Investigator
    K22AI132489     (AACHOUI, YOUSSEF)Aug 2, 2018 - Jul 31, 2020
    NIH/Nat. Inst. of Allergy & Infectious Diseases
    Mechanisms of Inflammasome Defense against Cytosol-invasive Bacteria - Continuation
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Oh C, Spears TJ, Aachoui Y. Inflammasome-mediated pyroptosis in defense against pathogenic bacteria. Immunol Rev. 2025 Jan; 329(1):e13408. PMID: 39404258.
      View in: PubMed
    2. Oh C, Li L, Verma A, Reuven AD, Miao EA, Bliska JB, Aachoui Y. Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins. Cell Rep. 2022 11 22; 41(8):111688. PMID: 36417874.
      View in: PubMed
    3. Oh C, Verma A, Hafeez M, Hogland B, Aachoui Y. Shigella OspC3 suppresses murine cytosolic LPS sensing. iScience. 2021 Aug 20; 24(8):102910. PMID: 34409271.
      View in: PubMed
    4. Oh C, Verma A, Aachoui Y. Caspase-11 Non-canonical Inflammasomes in the Lung. Front Immunol. 2020; 11:1895. PMID: 32973786.
      View in: PubMed
    5. Kovacs SB, Oh C, Maltez VI, McGlaughon BD, Verma A, Miao EA, Aachoui Y. Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium. Cell Rep. 2020 07 28; 32(4):107967. PMID: 32726630.
      View in: PubMed
    6. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 33458706.
      View in: PubMed
    7. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 27140198.
      View in: PubMed
    8. Sonderman KA, Wolf LL, Armstrong LB, Taylor K, Jiang W, Weil BR, Koehlmoos TP, Ricca RL, Weldon CB, Haider AH, Rice-Townsend SE. Testicular atrophy following inguinal hernia repair in children. Pediatr Surg Int. 2018 May; 34(5):553-560. PMID: 23707339.
      View in: PubMed
    9. Maltez VI, Tubbs AL, Cook KD, Aachoui Y, Falcone EL, Holland SM, Whitmire JK, Miao EA. Inflammasomes Coordinate Pyroptosis and Natural Killer Cell Cytotoxicity to Clear Infection by a Ubiquitous Environmental Bacterium. Immunity. 2015 Nov 17; 43(5):987-97. PMID: 26572063.
      View in: PubMed
    10. Aachoui Y, Kajiwara Y, Leaf IA, Mao D, Ting JP, Coers J, Aderem A, Buxbaum JD, Miao EA. Canonical Inflammasomes Drive IFN-? to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium. Cell Host Microbe. 2015 Sep 09; 18(3):320-32. PMID: 26320999.
      View in: PubMed
    11. Hagar JA, Powell DA, Aachoui Y, Ernst RK, Miao EA. Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock. Science. 2013 Sep 13; 341(6151):1250-3. PMID: 24031018.
      View in: PubMed
    12. Roy Chowdhury R, Aachoui Y, Ghosh SK. Effects of small intestinal submucosa (SIS) on the murine innate immune microenvironment induced by heat-killed Staphylococcus aureus. PLoS One. 2012; 7(11):e48724. PMID: 23189134.
      View in: PubMed
    13. Aachoui Y, Ghosh SK. Extracellular matrix from porcine small intestinal submucosa (SIS) as immune adjuvants. PLoS One. 2011; 6(11):e27083. PMID: 22087247.
      View in: PubMed
    14. Aachoui Y, Ghosh SK. Immune enhancement by novel vaccine adjuvants in autoimmune-prone NZB/W F1 mice: relative efficacy and safety. BMC Immunol. 2011 Oct 24; 12:61. PMID: 22024358.
      View in: PubMed
    15. Aachoui Y, Chowdhury RR, Fitch RW, Ghosh SK. Molecular signatures of phytol-derived immunostimulants in the context of chemokine-cytokine microenvironment and enhanced immune response. Cell Immunol. 2011; 271(2):227-38. PMID: 21813116.
      View in: PubMed
    16. McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 25267404.
      View in: PubMed
    17. McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 23348507.
      View in: PubMed
    18. McGoogan KE, Haafiz AB, Gonz?lez Peralta RP. Herpes simplex virus hepatitis in infants: clinical outcomes and correlates of disease severity. J Pediatr. 2011 Oct; 159(4):608-11. PMID: 21855057.
      View in: PubMed
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