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Gwen Childs

TitleDistinguished Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentDepartment Chairs, College of Medicine
Address934 Shorey
324 UAMS Campus Dr.
Mail Slot # 510
Little Rock AR 72205
Phone501-296-1260
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    Collapse Overview 
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    Collapse Research 
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    R01DK127723     (CHILDS, GWEN V)Jul 17, 2021 - Jun 30, 2025
    NIH
    The Impact of Obesity on Somatotrope Function
    Role: Principal Investigator
    R01HD093461     (MACNICOL, ANGUS M)Sep 1, 2018 - Jun 30, 2023
    NIH
    Control of pituitary cell plasticity through regulated mRNA translation
    Role: Co-Principal Investigator
    R01DK113776     (CHILDS, GWEN V)Apr 1, 2017 - Mar 31, 2021
    NIH
    Tropic Roles for Leptin in the Maturation of Somatotropes
    Role: Principal Investigator
    R01HD087057     (CHILDS, GWEN V)Aug 15, 2016 - Mar 31, 2021
    NIH
    Post-transcriptional Pathways that Signal Leptin Regulation of Gonadotropes
    Role: Principal Investigator
    R03HD082793     (CHILDS, GWEN V)Jul 10, 2015 - Jun 30, 2018
    NIH
    Leptin Molecular Regulatory Mechanisms That Prevent Growth hormone Deficiency
    Role: Principal Investigator
    DBI-0959745     (STORRIE, BRIAN)Jan 15, 2010 - Dec 31, 2012
    National Science Foundation
    120 kV FEI Electron Microscope and Supporting Sample Preparation Equipment for Biological Microscopy
    Role: Co-Investigator
    R01HD059056     (CHILDS, GWEN V.)Aug 15, 2009 - Jun 30, 2015
    NIH
    The Significance of Leptin Signals to Neonatal Somatotropes and Gonadotropes
    Role: Principal Investigator
    R03HD059066     (CHILDS, GWEN V)May 1, 2009 - Apr 30, 2012
    NIH
    Significance of Pituitary Leptin to Gonadotropes
    Role: Principal Investigator
    P20RR020146     (GARCIA-RILL, EDGAR E.)Sep 16, 2004 - Apr 30, 2014
    NIH
    Center for Translational Neuroscience
    Role: Co-Investigator
    R21HD047467     (CHILDS, GWEN V)Jul 1, 2004 - Jun 30, 2007
    NIH
    Cellular Basis for Non-Parallel Gonadotropin Release
    Role: Principal Investigator
    R03HD044875     (CHILDS, GWEN V)Apr 1, 2004 - Mar 31, 2007
    NIH
    Regulation of Leptin Production by Gonadotropes
    Role: Principal Investigator
    IBN-0240907     (CHILDS, GWEN)Apr 15, 2003 - Mar 31, 2006
    National Science Foundation
    Regulation of Leptin Expression and Function in the Anterior Pituitary
    Role: Principal Investigator
    R01HD033915     (CHILDS, GWEN V)Aug 1, 1996 - May 31, 2003
    NIH
    NOVEL SOMATOTROPE FUNCTIONS DURING OVULATION
    Role: Principal Investigator
    R01DK039553     (CHILDS, GWEN V)Mar 1, 1992 - Feb 29, 1996
    NIH
    FUNCTIONAL DIFFERENTIATION OF CORTICOTROPES
    Role: Principal Investigator
    R01HD015472     (CHILDS, GWEN V)May 1, 1981 - Aug 31, 1996
    NIH
    HORMONE STORAGE AND SECRETION BY GONADOTROPES
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Ruf-Zamojski F, Zhang Z, Zamojski M, Smith GR, Mendelev N, Liu H, Nudelman G, Moriwaki M, Pincas H, Castanon RG, Nair VD, Seenarine N, Amper MAS, Zhou X, Ongaro L, Toufaily C, Schang G, Nery JR, Bartlett A, Aldridge A, Jain N, Childs GV, Troyanskaya OG, Ecker JR, Turgeon JL, Welt CK, Bernard DJ, Sealfon SC. Single nucleus multi-omics regulatory landscape of the murine pituitary. Nat Commun. 2021 05 11; 12(1):2677. PMID: 33976139.
      View in: PubMed
    2. Odle AK, MacNicol MC, Childs GV, MacNicol AM. Post-Transcriptional Regulation of Gnrhr: A Checkpoint for Metabolic Control of Female Reproduction. Int J Mol Sci. 2021 Mar 24; 22(7). PMID: 33805020.
      View in: PubMed
    3. Allensworth-James M, Banik J, Odle A, Hardy L, Lagasse A, Moreira ARS, Bird J, Thomas CL, Avaritt N, Kharas MG, Lengner CJ, Byrum SD, MacNicol MC, Childs GV, MacNicol AM. Control of the Anterior Pituitary Cell Lineage Regulator POU1F1 by the Stem Cell Determinant Musashi. Endocrinology. 2021 03 01; 162(3). PMID: 33373440.
      View in: PubMed
    4. Childs GV, Odle AK, MacNicol MC, MacNicol AM. The Importance of Leptin to Reproduction. Endocrinology. 2021 02 01; 162(2). PMID: 33165520.
      View in: PubMed
    5. Miles TK, Silva Moreira AR, Allensworth-James ML, Odle AK, Haney AC, MacNicol AM, MacNicol MC, Childs GV. Sex differences in somatotrope response to fasting: biphasic responses in male mice. J Endocrinol. 2020 12; 247(3):213-224. PMID: 33112825.
      View in: PubMed
    6. Hendrix RD, Ou Y, Davis JE, Odle AK, Groves TR, Allen AR, Childs GV, Barger SW. Alzheimer amyloid-ß- peptide disrupts membrane localization of glucose transporter 1 in astrocytes: implications for glucose levels in brain and blood. Neurobiol Aging. 2021 01; 97:73-88. PMID: 33161213.
      View in: PubMed
    7. Childs GV, MacNicol AM, MacNicol MC. Molecular Mechanisms of Pituitary Cell Plasticity. Front Endocrinol (Lausanne). 2020; 11:656. PMID: 33013715.
      View in: PubMed
    8. Allensworth-James ML, Odle AK, Lim J, LaGasse AN, Miles TK, Hardy LL, Haney AC, MacNicol MC, MacNicol AM, Childs GV. Metabolic signalling to somatotrophs: Transcriptional and post-transcriptional mediators. J Neuroendocrinol. 2020 11; 32(11):e12883. PMID: 32657474.
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    9. Odle AK, Childs GV. SMAD-FOXL2 Regulation of FSHB: A Game of Human and Mouse. Endocrinology. 2020 07 01; 161(7). PMID: 32422656.
      View in: PubMed
    10. MacNicol AM, Odle AK, Childs GV. ELAVL1 Elevates Insights: The Ups and Downs of Regulated mRNA Translation in the Control of Gonadotropin Release. Endocrinology. 2019 10 01; 160(10):2466-2468. PMID: 31504402.
      View in: PubMed
    11. Zhao S, Zhu Y, Schultz RD, Li N, He Z, Zhang Z, Caron A, Zhu Q, Sun K, Xiong W, Deng H, Sun J, Deng Y, Kim M, Lee CE, Gordillo R, Liu T, Odle AK, Childs GV, Zhang N, Kusminski CM, Elmquist JK, Williams KW, An Z, Scherer PE. Partial Leptin Reduction as an Insulin Sensitization and Weight Loss Strategy. Cell Metab. 2019 10 01; 30(4):706-719.e6. PMID: 31495688.
      View in: PubMed
    12. Cragle CE, MacNicol MC, Byrum SD, Hardy LL, Mackintosh SG, Richardson WA, Gray NK, Childs GV, Tackett AJ, MacNicol AM. Musashi interaction with poly(A)-binding protein is required for activation of target mRNA translation. J Biol Chem. 2019 07 12; 294(28):10969-10986. PMID: 31152063.
      View in: PubMed
    13. Allensworth-James ML, Odle A, Haney A, MacNicol M, MacNicol A, Childs G. Sex-specific changes in postnatal GH and PRL secretion in somatotrope LEPR-null mice. J Endocrinol. 2018 09; 238(3):221-230. PMID: 29929987.
      View in: PubMed
    14. Odle A, Allensworth-James M, Childs GV. The War on the Placenta: The Differing Battles of High-Fat Diet and Obesity. Endocrinology. 2018 04 01; 159(4):1642-1643. PMID: 29471404.
      View in: PubMed
    15. Odle AK, Beneš H, Melgar Castillo A, Akhter N, Syed M, Haney A, Allensworth-James M, Hardy L, Winter B, Manoharan R, Syed R, MacNicol MC, MacNicol AM, Childs GV. Association of Gnrhr mRNA With the Stem Cell Determinant Musashi: A Mechanism for Leptin-Mediated Modulation of GnRHR Expression. Endocrinology. 2018 02 01; 159(2):883-894. PMID: 29228137.
      View in: PubMed
    16. Odle AK, Akhter N, Syed MM, Allensworth-James ML, Beneš H, Melgar Castillo AI, MacNicol MC, MacNicol AM, Childs GV. Leptin Regulation of Gonadotrope Gonadotropin-Releasing Hormone Receptors As a Metabolic Checkpoint and Gateway to Reproductive Competence. Front Endocrinol (Lausanne). 2017; 8:367. PMID: 29354094.
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    17. MacNicol MC, Cragle CE, McDaniel FK, Hardy LL, Wang Y, Arumugam K, Rahmatallah Y, Glazko GV, Wilczynska A, Childs GV, Zhou D, MacNicol AM. Evasion of regulatory phosphorylation by an alternatively spliced isoform of Musashi2. Sci Rep. 2017 09 14; 7(1):11503. PMID: 28912529.
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    18. Odle AK, Allensworth-James ML, Akhter N, Syed M, Haney AC, MacNicol M, MacNicol AM, Childs GV. A Sex-Dependent, Tropic Role for Leptin in the Somatotrope as a Regulator of POU1F1 and POU1F1-Dependent Hormones. Endocrinology. 2016 Oct; 157(10):3958-3971. PMID: 27571135.
      View in: PubMed
    19. Odle AK, Allensworth-James M, Haney A, Akhter N, Syed M, Childs GV. Adipocyte Versus Somatotrope Leptin: Regulation of Metabolic Functions in the Mouse. Endocrinology. 2016 Apr; 157(4):1443-56. PMID: 26859333.
      View in: PubMed
    20. Allensworth-James ML, Odle A, Haney A, Childs G. Sex Differences in Somatotrope Dependency on Leptin Receptors in Young Mice: Ablation of LEPR Causes Severe Growth Hormone Deficiency and Abdominal Obesity in Males. Endocrinology. 2015 Sep; 156(9):3253-64. PMID: 26168341.
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    21. Odle AK, Drew PD, Childs GV. Giant mice reveal new roles for GH in regulating the adipose immune microenvironment. Endocrinology. 2015 May; 156(5):1613-5. PMID: 25886070.
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    22. Odle AK, Haney A, Allensworth-James M, Akhter N, Childs GV. Adipocyte versus pituitary leptin in the regulation of pituitary hormones: somatotropes develop normally in the absence of circulating leptin. Endocrinology. 2014 Nov; 155(11):4316-28. PMID: 25116704.
      View in: PubMed
    23. Akhter N, CarlLee T, Syed MM, Odle AK, Cozart MA, Haney AC, Allensworth-James ML, Beneš H, Childs GV. Selective deletion of leptin receptors in gonadotropes reveals activin and GnRH-binding sites as leptin targets in support of fertility. Endocrinology. 2014 Oct; 155(10):4027-42. PMID: 25057790.
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    24. Syed M, Cozart M, Haney AC, Akhter N, Odle AK, Allensworth-James M, Crane C, Syed FM, Childs GV. Ghrelin restoration of function in vitro in somatotropes from male mice lacking the Janus kinase (JAK)-binding site of the leptin receptor. Endocrinology. 2013 Apr; 154(4):1565-76. PMID: 23417423.
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    25. Akhter N, Odle AK, Allensworth-James ML, Haney AC, Syed MM, Cozart MA, Chua S, Kineman R, Childs GV. Ablation of leptin signaling to somatotropes: changes in metabolic factors that cause obesity. Endocrinology. 2012 Oct; 153(10):4705-15. PMID: 22865370.
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    26. Akhter, Noor, Crane, Christopher, Childs GV. Pituitary Leptin-A Paracrine Regulator of Gonadotropes: A Review. The Open Journal of Neuroendocrinology. 2011; 25-42.
    27. Luque RM, Gahete MD, Cordoba-Chacon J, Childs GV, Kineman RD. Does the pituitary somatotrope play a primary role in regulating GH output in metabolic extremes? Ann N Y Acad Sci. 2011 Mar; 1220:82-92. PMID: 21388406.
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    28. Childs GV, Akhter N, Haney A, Syed M, Odle A, Cozart M, Brodrick Z, Gaddy D, Suva LJ, Akel N, Crane C, Benes H, Charlesworth A, Luque R, Chua S, Kineman RD. The somatotrope as a metabolic sensor: deletion of leptin receptors causes obesity. Endocrinology. 2011 Jan; 152(1):69-81. PMID: 21084451.
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    29. Childs GV. Pituitary Gland (Cell Types, Mediators, Development). 2008.
    30. Childs GV. Pituitary Gland (Cell Types, Mediators, Development). The New Encyclopedia of Neuroscience. 2008; 7:719-726.
    31. Burns ER, Garrett JE, Childs GV. A study of student performance on self-scheduled, computer-based examinations in a medical histology course: is later better? Med Teach. 2007 Nov; 29(9):990-2. PMID: 18158680.
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    32. Crane, C, Akhter, N, Johnson, BW, Iruthayanathan, M, Syed, F, Kudo, A, Zhou, Y-H, Childs, G. Fasting and glucose effects on pituitary leptin expression. Is leptin an local signal for nutrient status?. J Histochemistry and Cytochemistry. 2007; 55(10):1059-1073.
    33. Crane C, Akhter N, Johnson BW, Iruthayanathan M, Syed F, Kudo A, Zhou YH, Childs GV. Fasting and glucose effects on pituitary leptin expression: is leptin a local signal for nutrient status? J Histochem Cytochem. 2007 Oct; 55(10):1059-73. PMID: 17595338.
      View in: PubMed
    34. Akhter N, Johnson, BW, Crane, C, Kudo, A, Childs GV. Anterior Pituitary Leptin Expression Changes in Different Reproductive States: Stimulation, in vitro, by Gonadotropin releasing hormone (GnRH). J Histochemistry Cytochemistry. 2007; (55):151-166.
    35. Akhter N, Johnson BW, Crane C, Iruthayanathan M, Zhou YH, Kudo A, Childs GV. Anterior pituitary leptin expression changes in different reproductive states: in vitro stimulation by gonadotropin-releasing hormone. J Histochem Cytochem. 2007 Feb; 55(2):151-66. PMID: 17046838.
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    36. Childs GV, Iruthayanathan M, Akhter N, Johnson BW. Estrogen mediated cross talk between the ovary and pituitary somatotrope. Pre-ovulatory support for reproductive activity. Mol Cell Endocrinol. 2006 Mar 09; 247(1-2):60-3. PMID: 16443322.
      View in: PubMed
    37. Childs GV. Gonadotropes and Lactotropes. Physiology of Reproduction. J. Neill and E. Knobil, Eds, Elsevier Press, NY. 2006; 29:1483-1579.
    38. Childs, G.V. Physiology of Reproduction. Gonadotropes and Lactotropes. 2006; 29.
    39. Akhter, N, Johnson, BW, Crane, Christopher, Iruthayanathan, M, Zhou, YH, Kudo, A., Childs, GV. Anterior Pituitary Leptin Expression Changes in Different Reproductive States: Stimulation, In Vitro, by Gonadotropin Releasing Hormone (GnRH). J.. Histochem Cytochem. 2006.
    40. Iruthayanathan M, Zhou YH, Childs GV. Dehydroepiandrosterone restoration of growth hormone gene expression in aging female rats, in vivo and in vitro: evidence for actions via estrogen receptors. Endocrinology. 2005 Dec; 146(12):5176-87. PMID: 16150906.
      View in: PubMed
    41. Iruthayanathan M, Zhou Y, Childs GV. DHEA Restoration of GH Gene Expression in Aging Female Rats, in vivo and in vitro - Evidence for Actions Via Estrogen Receptors. Endocrinology. 2005; 146:5176-5187.
    42. Childs GV. In situ hybridization. Encyclopedia of Genetics, Galegroup Macmillan Reference USA, Farmington Hills, MI. 2005.
    43. Childs GV, Iruthayanathan M, Akhter N, Unabia G, Whitehead-Johnson B. Bipotential effects of estrogen on growth hormone synthesis and storage in vitro. Endocrinology. 2005 Apr; 146(4):1780-8. PMID: 15618363.
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    44. McDuffie IA, Akhter N, Childs GV. Regulation of leptin mRNA and protein expression in pituitary somatotropes. J Histochem Cytochem. 2004 Feb; 52(2):263-73. PMID: 14729878.
      View in: PubMed
    45. McDuffie I, Akhter N, Childs GV. Regulation of leptin expression in anterior pituitary somatotropes. J Histochem Cytochem. 2004; 52:263-273.
    46. Childs GV. Development of gonadotropes may involve cyclic transdifferentiation of growth hormone cells. Arch Physiol Biochem. 2002 Apr; 110(1-2):42-9. PMID: 11935399.
      View in: PubMed
    47. McCann SM, Karanth S, Mastronardi CA, Dees WL, Childs GV, Miller B, Sower S, Yu WH. Hypothalamic control of gonadotropin secretion. Prog. Brain Res. 2002; 141:151-164.
    48. Childs GV, Unabia G. Epidermal growth factor and gonadotropin-releasing hormone stimulate proliferation of enriched population of gonadotropes. Endocrinology. 2001 Feb; 142(2):847-53. PMID: 11159858.
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    49. Childs GV, Unabia G. Epidermal Growth factor and Gonadotropin releasing hormone stimulate proliferation of enriched populations of pituitary gonadotropes. Endocrinology. 2001; 142:847-854.
    50. Childs GV, Unabia G. The use of conterflow centrifugation to enrich gonadotropes and somatotropes. J Histochem Cytochem. 2001; 49:663-664.
    51. Childs GV. Sites of Epidermal Growth Factor synthesis and action in the anterior pituitary:Paracrine and autocrine interactions. Clinical and Exp Pharm and Physiol. 2001; 28:249-252.
    52. Childs GV. Growth hormone cells as co-gonadotropes: Partners in the regulation of reproductive system. Trends in Endocrinology and Metabolism. 2000; 11:168-174.
    53. Childs GV. Green fluorescent protein lights the way to a better understanding of the function and regulation of specific anterior pituitary cells. Editorial for Endocrinology. 2000; 141:4331-4333.
    54. Childs, G.V. Methods in Molecular Biology. In situ hybridization with non-radioactive probes. 1999; Vol 123.
    55. Armstrong J, Childs GV. Regulation of C-fos mRNA and Protein by EGF and GnRH within Proestrous Female Rat Anterior Pituitary Glands. J Histochem Cytochem. 1998; 46:935-943.
    56. Childs, G.V. Methods in Neuroendocrinology. Identification of biotinylated ligands on specific target cells in the pituitary. Studies of Regulation of binding, Methods in Neuroendocrinology. 1998.
    57. Childs GV. Gonadotropes. Encyclopedia of Reproduction. 1998; 184(2):498-506.
    58. Armstrong J, Childs GV. Differential Expression of c-fos in vitro by all anterior pituitary cell types during the estrous cycle: enhanced expression by luteinizing hormone but not follicle stimulating hormone cells. J Histochem Cytochem. 1997; 45(6):785-794.
    59. Childs GV. Cytochemical studies of multifunctional gonadotropes. Microscopy Research and Techniques. Microscopy Research and Techniques. 1997; 39:114-130.
    60. Fan X, Childs GV. EGF and TGF? mRNA and their Receptors in the Rat Anterior pituitary: Localization and Regulation. Endocrinology. 1995; 136:2284-2324.
    61. Fan Xuemo, Nagle GT, Collins TJ, Childs GV. Differential Regulation of EGF and TGFAlpha in the rat anterior pituitary and hypothalamus induced by stresses. Endocrinology. 1995; 136:873-880.
    62. Childs GV, Unabia G, Rougeau D. Cells that Express Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH) Beta (?) Subunit mRNAs during the Estrous Cycle: The major contributors contain LH?, FSH? and/or Growth Hormone. Endocrinology. 1994; 134:990-997.
    63. Childs GV, Geda Unabia, Brian T Miller. Cytochemical detection of GnRH binding sites on rat pituitary cells with LH, FSH and GH antigens during diestrous upregulation. Endocrinology. 1994; 134:1943-1951.
    64. Childs, G.V., Unabia, G., Rougeau, D. Proceedings of the IXth International Congress of Endocrinology, Satellite Symposium on Gonadotropins, GnRH. Subsets of Somatotropes bind GnRH and Express LH? and FSH? mRNA before the proestrous surges. 1993.
    65. Childs, G.V., Unabia, G., Kaiser, U., Chin, W. Proceedings of the IXth International Congress of Endocrinology Satellite Symposium on Gonadotropins, GnRH. Plasticity of expression of pituitary follistatin mRNA during the estrous cycle. 1993.
    66. Childs, G.V. Electron Microscopic Cytochemistry and Immunocytochemistry in Biomedicine. Contributions of Ultrastructural Cytochemistry to our Understanding of Anterior Pituitary Cytophysiology. 1993.
    67. Lee BL, Unabia G, Childs GV. Expression of follistatin mRNA in somatotropes and mammotropes early in the estrous cycle. J Histochem Cytochem. 1993; 41:955-960.
    68. Childs GV, Unabia G, Lloyd J. Recruitment and maturation of small subsets of luteinizing hormone (LH) gonadotropes during the estrous cycle. Endocrinology. 1992; 130:335-345.
    69. Childs GV, Unabia G, Lloyd JM. Maturation of FSH gonadotropes during the rat estrous cycle. Endocrinology. 1992; 131(1):29-36.
    70. Kaiser U, Lee BL, Unabia G, Chin W, Childs GV. Follistatin gene expression in gonadotropes and folliculostellate cells of diestrous rats. Endocrinology. 1992; 130(5):3048-3056.
    71. Lloyd, J.M., Tibolt, R., Childs, G.V. Current Topics in Pathology. Peptide hormone receptors. 1991.
    72. Childs GV, Westlund KN, Tibolt RE, Lloyd JM. Hypothalamic regulatory peptides and their receptors: their role in regulation at the adenohypophysial level. J. Elec. Mic. Tech. 1991; 19:21-41.
    73. Childs, GV. Neuroendocrine Research Methods, Vol 1 ed. London, New York: Greenstein, Harwood Academic Press; 1991. Chapter 2. The use of counterflow centrifugation to enrich pituitary corticotropes. The method and its perils and pitfalls. The use of counterflow centrifugation to enrich pituitary corticotropes. The method and its perils and pitfalls. 1991; 2.
    74. Childs GV, Taub K, Jones KE, Chin WW. Tri-ioodothyronine receptor ?2 mRNA expression by somatotropes and thyrotropes: Effect of propylthiouracil-induced hypothyroidism in rats. Endocrinol. 1991; 129:2767-2773.
    75. Childs GV. Multipotential pituitary cells that contain ACTH and other pituitary hormones. Trends in Endocrin. and Metab. 1991; 2(3):112-117.
    76. Marchetti C, Childs GV, Brown AM. Voltage-dependent calcium currents in gonadotropes separated by centrifugal elutriation. Amer. J. Physiol. 1990; E589-E596.
    77. Childs GV, Unabia G, Weirman ME, Gharib SD, Chin WW. Castration induces time-dependent changes in the FSH?-mRNA-containing gonadotrope cell population. Endocrinology. 1990; 126:2205-2213.
    78. Childs, GV. Methods in Enzymology. Localization of gonadotropin-releasing hormone receptors. 1990.
    79. Childs GV, Unabia G. Rapid corticosterone inhibition of CRH binding and ACTH release by enriched populations of corticotropes: Counteractions by AVP and its second messengers. Endocrinology. 1990; 126:1967-1975.
    80. Childs GV. Activation of protein Kinase C and voltage dependent calcium channels enhances binding of CRH by anterior pituitary cells. Mol. Endo. 1989; 3:117-126.
    81. Childs GV, Westlund K, Unabia G. Characterization of anterior pituitary target cells for arginine vasopressin: including cells that store adrenocorticotropin, thyrotropin-? and both hormones. Endocrinology. 1989; 125:554-559.
    82. Childs, G.V. Advances in Colloidal Gold Cytochemistry: Introduction. Am. J. Anat. 1989; (185):105-108.
    83. Lloyd JM, Childs GV. Differential storage and release of LH and FSH from individual gonadotropes separated by centrifugal elutriation. Endocrinology. 1988; 122:1282-1290.
    84. Drewe JA, Childs GV, Kunze DL. Synaptic transmission mediated by amino acids in isolated neurons from a mammalian medial solitary tract nucleus. Science. 1988; 241:1810-1812.
    85. Childs, G.V., Burke, J. Use of the reverse hemolytic plaque assay to study the regulation of anterior lobe ACTH secretion by CRF, AVP, A-II and glucocorticoids. Endocrinology. 1987; (120):439-444.
    86. Childs GV, Unabia G, Tibolt R, Lloyd JM. Cytological factors that support non-parallel secretion of LH and FSH during the estrous cycle. Endocrinology. 1987; 121:1801-1813.
    87. Childs GV, Lloyd J, Unabia G, Gharib SD, Wierman ME, Chin WW. Detection of LH? mRNA in individual gonadotropes after castration: use of a new in situ hybridization method with a photobiotinylated cRNA probe. Molecular Endocrinology. 1987; 1:926-932.
    88. May V, Wilber JF, U'Prichard DC, Childs GV. Persistence of immunoreactive TRH and GnRH in long-term primary anterior pituitary culture. Peptides. 1987; 8:543-558.
    89. Childs, GV, Marchetti, C, Brown, A.M. Involvement of sodium channels and two types of calcium channels in the regulation of ACTH release. Endocrinology. 1987; 5(120):2059-2069.
    90. Wynn, P.C., Suarez-Quian, C.A., Childs, G.V., Catt, K.J. Pituitary binding and internalization of GnRH agonist and antagonist analogues in vivo and in vitro. Endocrinology. 1986; (119):1852-1863.
    91. Naor, Z., Childs, G.V. Action and binding of gonadotropin releasing hormone to target cells in pituitary and gonads. Int'l Rev. Cytology. 1986; (103):147-187.
    92. Niendorf, A., Dietel, M., Arps, H., Lloyd, J., Childs, G.V. Visualization of binding sites for parathyroid hormone (1-84) on cultured kidney cells with Biotinyl-b-PTH (1-84). J. Histochem. Cytochem. 1986; (34):357-361.
    93. Childs, G.V., Hazum, E., Amsterdam, A., Limor, R., Naor, Z. Cytochemical evidence for different routes of GnRH processing by large gonadotropes and granulosa cells. Endocrinology. 1986; (119):1329-1338.
    94. Childs, G.V., Morell, J.L., Aguilera, G. Cytochemical studies of CRF receptors in anterior lobe corticotropes: Binding, glucocorticoid regulation and endocytosis of [Biotinyl-Ser1] CRF. Endocrinology. 1986; (119):2129-2142.
    95. Childs, G.V. (Editor). IMMUNOCYTOCHEMICAL TECHNOLOGY. 1986.
    96. Ibrahim, S.N., Moussa, S.M., Childs, G.V. Morphometric studies of rat anterior pituitary cells after gonadectomy: Correlation of changes in gonadotropes with serum levels of gonadotropins. Endocrinology. 1986; (119):629-637.
    97. Tibolt, R.E., Childs, G.V. Cytochemical and cytophysiological studies of GnRH target cells in the male rat pituitary: Differential effects of androgens and corticosterone on GnRH binding and gonadotropin release. Endocrinology. 1985; 117(1):396-404.
    98. Westlund, K.N., Aguilera, G., Childs, G.V. Quantification of morphological changes in pituitary corticotropes produced by in vivo CRF stimulation and adrenalectomy. Endocrinology. 1985; (116):439-445.
    99. Childs, G.V., Ellison, D.G., Collins, T.J., Lorenzen, J.R., Schwartz, N.B. Retardation of the development of castration cells by adrenalectomy or sham adrenalectomy. Endocrinology. 1983; (113):166-177.
    100. Childs, G.V., Hyde, C., Naor, Z., Catt, K. Heterogeneous LH and FSH storage patterns in subtypes of gonadotropes separated by centrifugal elutriation. Endocrinology. 1983; (113):2120-2128.
    101. Childs GV. The Use of Multiple Methods to Validate Immunocytochemical Stains 12. J Histochem Cytochem. 1983 Jan; 31(1A_suppl):168-176. PMID: 28054856.
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    102. Childs, G.V., Unabia, G. The application of a new rapid avidin-biotin peroxidase complex (ABC) method to the electron microscopic localization of pituitary hormones. J. Histochem. Cytochem. 1982; (30):1320-1324.
    103. Hyde, C.L., Childs, G.V., Wahl, L.M., Naor, Z., Catt, K.J. Preparation of gonadotropin-enriched cell populations from adult rat anterior pituitary cells by centrifugal elutriation. Endocrinology. 1982; (111):1421-1423.
    104. Childs, G.V. ELECTRON MICROSCOPY IN BIOLOGY, Vol. 2 J. The use of immunocytochemical techniques in cellular endocrinology. 1982.
    105. Childs, G.V., Ellison, D.G., Ramaley, J.A. Adrenocorticotropin storage in corticotropes and a subpopulation of gonadotropes during the stress non-responsive period in the neonatal male rat. Endocrinology. 1982; (110):1676-1692.
    106. Naor, Z., Childs, G.V., Leifer, A.J., Clayton, R.N., Amsterdam, A., Catt, K.J. Gonadotropin releasing hormone binding and activation of enriched population of pituitary gonadotropes. Mol. Cell Endocrin. 1982; (25):85-98.
    107. Dudek, R.W., Childs, G.V., Boyne, A.F. Quick-freezing and freeze drying in preparation for high quality morphology and immunocytochemistry at the ultrastructural level. J. Histochem. Cytochem. 1982; (30):129-138.
    108. Childs, G.V., Unabia, G. Application of the avidin-biotin peroxidase complex method to the light microscopic localization of pituitary hormones. J. Histochem. Cytochem. 1982; (30):713-716.
    109. Childs, G.V., Ellison, D.G., Yang, H.-Y., Kubek, M., Childs GV, Tobin, R.B, Wilber, J.F. The effect of thyroidectomy, propylthiouracil and thyroxine on pituitary content and immunocytochemical staining of thyrotropin and thyrotropin releasing hormone. J. Histochem. Cytochem. 1981; (29):357-363.
    110. Bauer, T.W., Childs, G.V. Studies of immunoreactive gonadotropin releasing hormone (GnRH) in the rat anterior pituitary. J. Histochem. Cytochem. 1981; (29):1171-1178.
    111. Childs, G.V., Ellison, D.G., Foster, L., Ramaley, J.A. Postnatal maturation of gonadotropes in the male rat pituitary. Endocrinology. 1981; (109):1683-1693.
    112. Childs, G.V., Hutson, J.C., Bauer, T.W. DIAGNOSTIC IMMUNOHISTOCHEMISTRY. Immunocytochemical detection of hormones at target binding sites. 1981; 10.
    113. Ellison, D.G., Childs, G.V. An improved method for the rapid collection of serial cells for electron microscopic analysis of their immunocytochemical stain. J. Histochem. Cytochem. 1980; (28):279-281.
    114. Childs, G.V., Ellison, D.G. Critique of the contributions of immunoperoxidase cytochemistry to our understanding of pituitary cell function. The Histochem. J. 1980; (12):405-418.
    115. G.V. Childs, Cole, D.E. 37th ed. San Antonio, Texas: G.W. Bailey (ed); 1979. Contributions of immunoperoxidase cytochemistry to our understanding of pituitary cell function. Contributions of immunoperoxidase cytochemistry to our understanding of pituitary cell function. 1979.
    116. Hutson, J.C., Childs, G.V., Gardner, P.J. Considerations for establishing the biological significance of immunocytochemical stains. J. Histochem. Cytochem. 1979; (27):1201-1202.
    117. Childs, G. STRUCTURE AND FUNCTION OF GONADOTROPIN. Immunocytochemical demonstration of endogenous gonadotropin binding sites in the fetal rat testes. 1978; 23.
    118. Halm, N.S., Moriarty, G.C. The origin of ACTH in man. Ann. NY Acad. Sci. 1977; (297):170-182.
    119. Halmi, N.S., Moriarty, G.C. HISTOLOGY. The hypophysis (pituitary gland). 1977; 27.
    120. Moriarty, G.C., Garner, L.L. Immunocytochemical studies of cells in the rat adenohypophysis containing both ACTH and FSH. Nature. 1977; (265):356-358.
    121. Moriarty, G.C. Heterogeneity of ACTH containing cells in the rat pituitary (with emphasis on the structure and function of the intermediate lobe). Ann. NY Acad. Sci. 1977; (297):183-197.
    122. Hutson, J.C., Gardner, P.J., Moriarty, G.C. Immunocytochemical localization of a follicle stimulating hormone-like molecule in the testis. J. Histochem. Cytochem. 1977; (25):163-174.
    123. Spaur, R.C., Moriarty, G.C. Improvements of glycol methacrylate. I. Its use as an embedding medium for electron microscopic studies. J. Histochem. Cytochem. 1977; (25):1637-1674.
    124. Moriarty, G.C. Ultrastructural-immunocytochemical studies of gonadotrophs. Gunna Symposium on Endocrinology, Biology of Reproduction and its Hormonal Control. 1976; (13):207-219.
    125. Moriarty, G.C., Tobin, R.B. An immunocytochemical study of TSH storage in rat thyroidectomy cells with and without D or L thyroxine treatment. J. Histochem. Cytochem. 1976; (24):1140-1149.
    126. Moriarty, G.C., Tobin, R.B. Immunocytochemical characterization of the thyrotroph in rat and human pituitaries. J. Histochem. Cytochem. 1976; (24):1131-1139.
    127. Moriarty, G.C. Immunocytochemistry of the pituitary glycoprotein hormones. J. Histochem. Cytochem. 1976; (24):846-863.
    128. Moriarty, C.M., Moriarty, G.C. Bioactive and immunoreactive ACTH in the rat pituitary: Influence of stress and adrenalectomy. Endocrinology. 1975; (96):1419-1425.
    129. Moriarty, G.C. Electron microscopic-immunocytochemical studies of rat pituitary gonadotrophs: A sex difference in morphology and cytochemistry of LH cells. Endocrinology. 1975; (97):1215-1225.
    130. Moriarty, G.C., Halmi, N.S., Moriarty, C.M. The effect of stress on the cytology and immunocytochemistry of pars intermedia cells in the rat pituitary. Endocrinology. 1975; (96):1426-1436.
    131. Petrali, J.P., Hinton, D.H., Moriarty, G.C., Sternberger, L.A. Quantitative immunocytochemistry of corticotropin by the unlabeled antibody enzyme method with and without peroxidase-antiperoxidase complex (PAP). J. Histochem. Cytochem. 1974; (22):782-801.
    132. Moriarty, G.C., Moriarty, C.M., Sternberger, L.A. Ultrastructural immunocytochemistry with unlabeled antibodies and the peroxidase-anti- peroxidase complex: A technique more sensitive than radioimmunoassay. J. Histochem. Cytochem. 1973; (21):825-833.
    133. Moriarty, G.C. Adenohypophysis: Ultrastructural cytochemistry. A review. J. Histochem. Cytochem. 1973; (21):855-892.
    134. Moriarty, G.C. Adrenocorticotropin production by the anterior and intermediate lobes of the rat pituitary. An electron microscopic-immunocytochemical study. 1972.
    135. Moriarty, G.C., Halmi, N.S. Adrenocorticotropin-production by the intermediate lobe of the rat pituitary. An electron microscopic study. Z. Zellforsch. 1972; (132):1-14.
    136. Moriarty, G.C., Halmi, N.S. Electron microscopic localization of the adrenocorticotropin producing cell with the use of unlabeled antibody and the peroxidase-antiperoxidase complex. J. Histochem. Cytochem. 1972; (20):590-603.
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