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Angela Odle

TitleAssistant Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentNeurobiology & Developmental Science, College of Medicine
DivisionNeuro & Devel SFaculty
Address Biomedical Research I
325 S. Elm St.
Mail Slot # 510
Little Rock AR 72205
Phone501-686-5166
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    Collapse Research 
    Collapse research activities and funding
    90INNU0036     (OVERTON-MCCOY, AMY)Aug 1, 2022 - Jul 31, 2025
    Administration for Community Living
    Enhancement Project to Improve Access to Food Services and Mental Well-Being
    Role: Principal Investigator
    90INNU0036-01-00     (OVERTON-MCCOY, AMY)Aug 1, 2022 - Jul 31, 2025
    Administration for Community Living
    Enhancement Project to Improve Access to Food Services and Mental Well-Being
    Role: Principal Investigator
    90INNU0036-02-00     (OVERTON-MCCOY, AMY)Aug 1, 2022 - Jul 31, 2025
    Administration for Community Living
    Enhancement Project to Improve Access to Food Services and Mental Well-Being
    Role: Principal Investigator
    4600048381     (OVERTON-MCCOY, AMY)Apr 1, 2021 - Dec 31, 2021
    Arkansas Department of Human Services
    DPSQA Choices in Living Resource Center Lifespan Respite Training
    Role: Principal Investigator
    R01HD087057     (CHILDS, GWEN V)Aug 15, 2016 - Mar 31, 2021
    NIH
    Post-transcriptional Pathways that Signal Leptin Regulation of Gonadotropes
    Role: Co-Investigator
    R01HD059056     (CHILDS, GWEN V.)Aug 15, 2009 - Jun 30, 2015
    NIH
    The Significance of Leptin Signals to Neonatal Somatotropes and Gonadotropes
    Role: Co-Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions. Don't see publications published under other names? Login to add alternative names.
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    1. Banik J, Moreira ARS, Lim J, Tomlinson S, Hardy LL, Lagasse A, Haney A, Crimmins MR, Boehm U, Odle AK, MacNicol MC, Childs GV, MacNicol AM. The Musashi RNA binding proteins direct the translational activation of key pituitary mRNAs. Sci Rep. 2024 03 11; 14(1):5918. PMID: 38467682.
      View in: PubMed
    2. Miles TK, Odle AK, Byrum SD, Lagasse A, Haney A, Ortega VG, Bolen CR, Banik J, Reddick MM, Herdman A, MacNicol MC, MacNicol AM, Childs GV. Anterior Pituitary Transcriptomics Following a High-Fat Diet: Impact of Oxidative Stress on Cell Metabolism. Endocrinology. 2023 Dec 23; 165(2). PMID: 38103263.
      View in: PubMed
    3. Sundaram VK, Sch?tza V, Schr?ter NH, Backhaus A, Bilsing A, Joneck L, Seelbach A, Mutschler C, Gomez-Sanchez JA, Sch?ffner E, S?nchez EE, Akkermann D, Paul C, Schwagarus N, M?ller S, Odle A, Childs G, Ewers D, Kungl T, Sitte M, Salinas G, Sereda MW, Nave KA, Schwab MH, Ost M, Arthur-Farraj P, Stassart RM, Fledrich R. Adipo-glial signaling mediates metabolic adaptation in peripheral nerve regeneration. Cell Metab. 2023 12 05; 35(12):2136-2152.e9. PMID: 37989315.
      View in: PubMed
    4. Moreira ARS, Lim J, Urbaniak A, Banik J, Bronson K, Lagasse A, Hardy L, Haney A, Allensworth M, Miles TK, Gies A, Byrum SD, Wilczynska A, Boehm U, Kharas M, Lengner C, MacNicol MC, Childs GV, MacNicol AM, Odle AK. Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle. Endocrinology. 2023 08 01; 164(9). PMID: 37477898.
      View in: PubMed
    5. Trujillo M, Odle AK, Aykin-Burns N, Allen AR. Chemotherapy induced oxidative stress in the ovary: drug-dependent mechanisms and potential interventions?. Biol Reprod. 2023 04 11; 108(4):522-537. PMID: 36539327.
      View in: PubMed
    6. Odle AK, MacNicol MC, Childs GV, MacNicol AM. Post-Transcriptional Regulation of Gnrhr: A Checkpoint for Metabolic Control of Female Reproduction. Int J Mol Sci. 2021 Mar 24; 22(7). PMID: 33805020.
      View in: PubMed
    7. Childs GV, Odle AK, MacNicol MC, MacNicol AM. The Importance of Leptin to Reproduction. Endocrinology. 2021 02 01; 162(2). PMID: 33165520.
      View in: PubMed
    8. Miles TK, Silva Moreira AR, Allensworth-James ML, Odle AK, Haney AC, MacNicol AM, MacNicol MC, Childs GV. Sex differences in somatotrope response to fasting: biphasic responses in male mice. J Endocrinol. 2020 12; 247(3):213-224. PMID: 33112825.
      View in: PubMed
    9. Hendrix RD, Ou Y, Davis JE, Odle AK, Groves TR, Allen AR, Childs GV, Barger SW. Alzheimer amyloid-?- peptide disrupts membrane localization of glucose transporter 1 in astrocytes: implications for glucose levels in brain and blood. Neurobiol Aging. 2021 01; 97:73-88. PMID: 33161213.
      View in: PubMed
    10. Allensworth-James ML, Odle AK, Lim J, LaGasse AN, Miles TK, Hardy LL, Haney AC, MacNicol MC, MacNicol AM, Childs GV. Metabolic signalling to somatotrophs: Transcriptional and post-transcriptional mediators. J Neuroendocrinol. 2020 11; 32(11):e12883. PMID: 32657474.
      View in: PubMed
    11. Odle AK, Childs GV. SMAD-FOXL2 Regulation of FSHB: A Game of Human and Mouse. Endocrinology. 2020 07 01; 161(7). PMID: 32422656.
      View in: PubMed
    12. MacNicol AM, Odle AK, Childs GV. ELAVL1 Elevates Insights: The Ups and Downs of Regulated mRNA Translation in the Control of Gonadotropin Release. Endocrinology. 2019 10 01; 160(10):2466-2468. PMID: 31504402.
      View in: PubMed
    13. Zhao S, Zhu Y, Schultz RD, Li N, He Z, Zhang Z, Caron A, Zhu Q, Sun K, Xiong W, Deng H, Sun J, Deng Y, Kim M, Lee CE, Gordillo R, Liu T, Odle AK, Childs GV, Zhang N, Kusminski CM, Elmquist JK, Williams KW, An Z, Scherer PE. Partial Leptin Reduction as an Insulin Sensitization and Weight Loss Strategy. Cell Metab. 2019 10 01; 30(4):706-719.e6. PMID: 31495688.
      View in: PubMed
    14. Allensworth-James ML, Odle A, Haney A, MacNicol M, MacNicol A, Childs G. Sex-specific changes in postnatal GH and PRL secretion in somatotrope LEPR-null mice. J Endocrinol. 2018 09; 238(3):221-230. PMID: 29929987.
      View in: PubMed
    15. Odle A, Allensworth-James M, Childs GV. The War on the Placenta: The Differing Battles of High-Fat Diet and Obesity. Endocrinology. 2018 04 01; 159(4):1642-1643. PMID: 29471404.
      View in: PubMed
    16. Odle AK, Bene? H, Melgar Castillo A, Akhter N, Syed M, Haney A, Allensworth-James M, Hardy L, Winter B, Manoharan R, Syed R, MacNicol MC, MacNicol AM, Childs GV. Association of Gnrhr mRNA With the Stem Cell Determinant Musashi: A Mechanism for Leptin-Mediated Modulation of GnRHR Expression. Endocrinology. 2018 02 01; 159(2):883-894. PMID: 29228137.
      View in: PubMed
    17. Odle AK, Akhter N, Syed MM, Allensworth-James ML, Bene? H, Melgar Castillo AI, MacNicol MC, MacNicol AM, Childs GV. Leptin Regulation of Gonadotrope Gonadotropin-Releasing Hormone Receptors As a Metabolic Checkpoint and Gateway to Reproductive Competence. Front Endocrinol (Lausanne). 2017; 8:367. PMID: 29354094.
      View in: PubMed
    18. Odle AK, Allensworth-James ML, Akhter N, Syed M, Haney AC, MacNicol M, MacNicol AM, Childs GV. A Sex-Dependent, Tropic Role for Leptin in the Somatotrope as a Regulator of POU1F1 and POU1F1-Dependent Hormones. Endocrinology. 2016 Oct; 157(10):3958-3971. PMID: 27571135.
      View in: PubMed
    19. Odle AK, Allensworth-James M, Haney A, Akhter N, Syed M, Childs GV. Adipocyte Versus Somatotrope Leptin: Regulation of Metabolic Functions in the Mouse. Endocrinology. 2016 Apr; 157(4):1443-56. PMID: 26859333.
      View in: PubMed
    20. Allensworth-James ML, Odle A, Haney A, Childs G. Sex Differences in Somatotrope Dependency on Leptin Receptors in Young Mice: Ablation of LEPR Causes Severe Growth Hormone Deficiency and Abdominal Obesity in Males. Endocrinology. 2015 Sep; 156(9):3253-64. PMID: 26168341.
      View in: PubMed
    21. Odle AK, Drew PD, Childs GV. Giant mice reveal new roles for GH in regulating the adipose immune microenvironment. Endocrinology. 2015 May; 156(5):1613-5. PMID: 25886070.
      View in: PubMed
    22. Hyde J, MacNicol M, Odle A, Garcia-Rill E. The use of three-dimensional printing to produce in vitro slice chambers. J Neurosci Methods. 2014 Dec 30; 238:82-7. PMID: 25251556.
      View in: PubMed
    23. Odle AK, Haney A, Allensworth-James M, Akhter N, Childs GV. Adipocyte versus pituitary leptin in the regulation of pituitary hormones: somatotropes develop normally in the absence of circulating leptin. Endocrinology. 2014 Nov; 155(11):4316-28. PMID: 25116704.
      View in: PubMed
    24. Akhter N, CarlLee T, Syed MM, Odle AK, Cozart MA, Haney AC, Allensworth-James ML, Bene? H, Childs GV. Selective deletion of leptin receptors in gonadotropes reveals activin and GnRH-binding sites as leptin targets in support of fertility. Endocrinology. 2014 Oct; 155(10):4027-42. PMID: 25057790.
      View in: PubMed
    25. Syed M, Cozart M, Haney AC, Akhter N, Odle AK, Allensworth-James M, Crane C, Syed FM, Childs GV. Ghrelin restoration of function in vitro in somatotropes from male mice lacking the Janus kinase (JAK)-binding site of the leptin receptor. Endocrinology. 2013 Apr; 154(4):1565-76. PMID: 23417423.
      View in: PubMed
    26. Akhter N, Odle AK, Allensworth-James ML, Haney AC, Syed MM, Cozart MA, Chua S, Kineman R, Childs GV. Ablation of leptin signaling to somatotropes: changes in metabolic factors that cause obesity. Endocrinology. 2012 Oct; 153(10):4705-15. PMID: 22865370.
      View in: PubMed
    27. Childs GV, Akhter N, Haney A, Syed M, Odle A, Cozart M, Brodrick Z, Gaddy D, Suva LJ, Akel N, Crane C, Benes H, Charlesworth A, Luque R, Chua S, Kineman RD. The somatotrope as a metabolic sensor: deletion of leptin receptors causes obesity. Endocrinology. 2011 Jan; 152(1):69-81. PMID: 21084451.
      View in: PubMed
    28. Beck P, Odle A, Wallace-Huitt T, Skinner RD, Garcia-Rill E. Modafinil increases arousal determined by P13 potential amplitude: an effect blocked by gap junction antagonists. Sleep. 2008 Dec; 31(12):1647-54. PMID: 19090320.
      View in: PubMed
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