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Last Name
Institution

Aliza Brown

TitleAssistant Research Professor
InstitutionUniversity of Arkansas for Medical Sciences
DepartmentRadiology, College of Medicine
DivisionRadiology Science Research
AddressS6/30 Shorey
324 UAMS Campus Dr.
Mail Slot # 556
Little Rock AR 72205
Phone501-686-6769
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    Other Roles
    Center for Distance Health, AR SAVES Program Evaluator

    Collapse Affiliation 
    Collapse member of
    American Heart Association
    National Stroke Association
    North American Vascular Biological Organization
    Collapse collaborator
    William Culp, MD
    Robert Skinner, PhD
    Chronic Disease Branch, Arkansas Dept of Health
    Feifei Wei, PhD
    Paula Roberson, PhD

    Collapse Biography 
    Collapse awards and honors
    2016 - 2017Center for Translational Neuroscience Telemedicine Core Facility, P30 GM 110702; NIH/NIGMS/IDeA
    2016 - 2017Challenge Study to Improve Time to Thrombolysis in the AR SAVES Telestroke Spoke Sites, UAMS, COM, THE FUND TO CURE STROKE
    2015 - 2017Pilot study to validate a paramedic training video covering stroke recognition during patient triage, Genentech, CGN

    Collapse Outreach 

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Arthur MC, Brown A, Carlson K, Lowery J, Skinner RD, Culp WC. Dodecafluoropentane Improves Neurological Function Following Anterior Ischemic Stroke. Mol Neurobiol. 2017 Aug; 54(6):4764-4770. PMID: 27501802.
      View in: PubMed
    2. Brown AT, Wei F, Culp WC, Brown G, Tyler R, Balamurugan A, Bianchi N. Emergency transport of stroke suspects in a rural state: opportunities for improvement. Am J Emerg Med. 2016 Aug; 34(8):1640-4. PMID: 27344100; PMCID: PMC4998736.
    3. Fitzgerald RT, Ou X, Nix JS, Arthur MC, Brown AT, Skinner RD, Borrelli MJ, Culp WC. Magnetic Resonance Imaging. Dodecafluoropentane emulsion delays and reduces MRI markers of infarction in a rat stroke model. 2015; 33:236-239.
    4. Culp WC, Brown AT, Lowery JD, Arthur MC, Roberson PK, Skinner RD. Dodecafluoropentane Emulsion Extends Window for tPA Therapy in a Rabbit Stroke Model. Mol Neurobiol. 2015 Oct; 52(2):979-84. PMID: 26055229; PMCID: PMC4998836.
    5. Brown AT, Arthur MC, Nix JS, Montgomery JA, Skinner RD, Roberson PK, Borrelli M, Culp WC. Dodecafluoropentane Emulsion (DDFPe) Decreases Stroke Size and Improves Neurological Scores in a Permanent Occlusion Rat Stroke Model. Open Neurol J. 2014; 8:27-33. PMID: 25674164; PMCID: PMC4321204.
    6. Fitzgerald RT, Ou X, Nix JS, Arthur MC, Brown AT, Skinner RD, Borrelli MJ, Culp WC. Dodecafluoropentane emulsion delays and reduces MRI markers of infarction in a rat stroke model: a preliminary report. Magn Reson Imaging. 2015 Feb; 33(2):236-9. PMID: 25460332.
      View in: PubMed
    7. Fitzgerald RT, Wright SM, Samant RS, Kumar M, Ramakrishnaiah RH, Van Hemert R, Brown AT, Angtuaco EJ. Elevation of serum lactate dehydrogenase at posterior reversible encephalopathy syndrome onset in chemotherapy-treated cancer patients. J Clin Neurosci. 2014 Sep; 21(9):1575-8. PMID: 24780237.
      View in: PubMed
    8. Brown A, Woods S, Skinner R, Hatton J, Lowery J, Roberson P, Hennings L, Culp WC. Neurological assessment scores in rabbit embolic stroke models. Open Neurol J. 2013; 7:38-43. PMID: 24265650; PMCID: PMC3831307.
    9. Woods SD, Skinner RD, Ricca AM, Brown AT, Lowery JD, Borrelli MJ, Lay JO, Culp WC. Progress in dodecafluoropentane emulsion as a neuroprotective agent in a rabbit stroke model. Mol Neurobiol. 2013 Oct; 48(2):363-7. PMID: 23813100; PMCID: PMC3787698.
    10. Erdem E, Samant R, Malak SF, Culp WC, Brown A, Peterson L, Lensing S, Barlogie B. Vertebral augmentation in the treatment of pathologic compression fractures in 792 patients with multiple myeloma. Leukemia. 2013 Dec; 27(12):2391-3. PMID: 23728152; PMCID: PMC3865531.
    11. Culp WC, Woods SD, Brown AT, Lowery JD, Hennings LJ, Skinner RD, Borrelli MJ, Roberson PK. Three variations in rabbit angiographic stroke models. J Neurosci Methods. 2013 Jan 30; 212(2):322-8. PMID: 23142182; PMCID: PMC3563856.
    12. Chaudhuri S, McCullough SS, Hennings L, Brown AT, Li SH, Simpson PM, Hinson JA, James LP. Effect of trifluoperazine on toxicity, HIF-1alpha induction and hepatocyte regeneration in acetaminophen toxicity in mice. Toxicol Appl Pharmacol. 2012; 264(2):192-201.
    13. Berridge, MS, Hatton, JH, Apana, SM, Carpenter, C, Lowery, JD, Alpe, TL, Borrelli, MJ, Brown, AT, Culp, WC. F-18 labelled blood clots for measurement of therapeutic efficacy in a rabbit stroke model. World Molecular Imaging Congress. 2012.
    14. Brown AT, Woods, SD, Skinner, RD, Ricca, AM, Brown, AT, Lowery, JD, Borrelli, MJ, Culp, WC. Dodecafluoropentane emulsion decreases infarct volume in a rabbit model of acute ischemic stroke. 11th International Conference on Neuroprotective Agents. 2012.
    15. Culp WC, Woods SD, Skinner RD, Brown AT, Lowery JD, Johnson JL, Unger EC, Hennings LJ, Borrelli MJ, Roberson PK. Dodecafluoropentane emulsion decreases infarct volume in a rabbit ischemic stroke model. J Vasc Interv Radiol. 2012 Jan; 23(1):116-21. PMID: 22079515; PMCID: PMC3253225.
    16. Brown AT, Ou X, James LP, Jambhekar K, Pandey T, McCullough S, Chaudhuri S, Borrelli MJ. Correlation of MRI findings to histology of acetaminophen toxicity in the mouse. Magn Reson Imaging. 2012 Feb; 30(2):283-9. PMID: 22055850; PMCID: PMC3254831.
    17. Nyalala JO, Brown AT, Luo S, Deng H, Moursi MM. Estrogen replacement attenuates exaggerated neointimal hyperplasia following carotid endarterectomy in rats. Vasc Endovascular Surg. 2011 Nov; 45(8):720-6. PMID: 22262116.
      View in: PubMed
    18. Hennings LJ, Flores R, Roberson PK, Brown A, Lowery J, Borrelli M, Culp WC. Persistent penumbra in a rabbit stroke model: incidence and histologic characteristics. Stroke Res Treat. 2011; 2011:764830. PMID: 21776366; PMCID: PMC3138104.
    19. Flores R, Hennings LJ, Lowery JD, Brown AT, Culp WC. Microbubble-augmented ultrasound sonothrombolysis decreases intracranial hemorrhage in a rabbit model of acute ischemic stroke. Invest Radiol. 2011 Jul; 46(7):419-24. PMID: 21343824; PMCID: PMC3109116.
    20. Culp WC, Flores R, Brown AT, Lowery JD, Roberson PK, Hennings LJ, Woods SD, Hatton JH, Culp BC, Skinner RD, Borrelli MJ. Successful microbubble sonothrombolysis without tissue-type plasminogen activator in a rabbit model of acute ischemic stroke. Stroke. 2011 Aug; 42(8):2280-5. PMID: 21700942; PMCID: PMC3266124.
    21. Caldwell B, Flores R, Lowery J, Brown AT, Culp WC. Variations in the circle of Willis in the New Zealand white rabbit. J Vasc Interv Radiol. 2011 Aug; 22(8):1188-92. PMID: 21507678; PMCID: PMC3148303.
    22. Brown AT, Flores R, Hamilton E, Roberson PK, Borrelli MJ, Culp WC. Microbubbles improve sonothrombolysis in vitro and decrease hemorrhage in vivo in a rabbit stroke model. Invest Radiol. 2011 Mar; 46(3):202-7. PMID: 21150788; PMCID: PMC3845811.
    23. Culp WC, Flores R, Lowery JD, Brown AT, Hennings LJ, Roberson PK, Woods SD, Hatton JH, Culp BC, Skinner RD, Borrelli MJ. Successful micrbubble sonothromolysis without tissue plaminogen activator in a rabbit model of acute ischemic stroke. Stroke. 2011; 42(8):2280-2285.
    24. Atherton ME, Culp WC, Brown AT, Erdem E. Successful intravascular ultrasound thrombolysis of dural sinus thrombosis with pre-existing subarachnoid and intraparenchymal hemorrhages. Interv Neuroradiol. 2010 Dec; 16(4):455-8. PMID: 21162778; PMCID: PMC3278010.
    25. Nyalala JO, Luo S, Campbell DN, Brown AT, Moursi MM. The effects of acarbose treatment on intimal hyperplasia in a rat carotid endarterectomy model of diet-induced insulin resistance. Vasc Endovascular Surg. 2010 Oct; 44(7):560-7. PMID: 20675317.
      View in: PubMed
    26. Brown AT, Skinner RD, Flores R, Hennings L, Borrelli MJ, Lowery J, Culp WC. Stroke location and brain function in an embolic rabbit stroke model. J Vasc Interv Radiol. 2010 Jun; 21(6):903-9. PMID: 20417119; PMCID: PMC2875361.
    27. Nyalala JO, Luo S, Campbell DN, Brown AT, Moursi MM. The effects of acarbose treatment on intimal hyperplasia in a rat carotid edarterectomy model of diet induced insulin resistence. Vasc Endovacular Surg. 2010; 44:560-67.
    28. Brown AT, Skinner RD, Flores R, Hennings L, Lowery J, Culp WC. Correlation of stroke volume, brain structures and functional recovery in an embolic rabbit stroke model. J Vasc Interv Radiol. 2009; 20(Suppl 1):599.
    29. Kalapatapu VR, Satterfield L, Brown AT. The effects of Toradol on postoperative intimal hyperplasia in a rat carotid endarterectomy model: laboratory research. Vasc Endovascular Surg. 2007 Oct-Nov; 41(5):402-8. PMID: 17942855.
      View in: PubMed
    30. Culp WC, Brown AT, Hennings L, Lowery J, Culp BC, Erdem E, Roberson P, Matsunaga TO. Safety of high dose microbubbles and transcranial ultrasound in rabbits. 6th International Symposium on Therapeutic Ultrasound. 2007; 911:542-546.
    31. Culp BC, Brown AT, Erdem E, Lowery J, Culp WC. Selective intracranial magnification angiography of the rabbit: basic techniques and anatomy. J Vasc Interv Radiol. 2007 Feb; 18(2):187-92. PMID: 17327550.
      View in: PubMed
    32. Bledsoe SL, Barr JC, Fitzgerald RT, Brown AT, Faas FH, Eidt JF, Moursi MM. Pravastatin and clopidogrel combined inhibit intimal hyperplasia in a rat carotid endarterectomy model. Vasc Endovascular Surg. 2006 Jan-Feb; 40(1):49-57. PMID: 16456606.
      View in: PubMed
    33. Qureshi I, Chen H, Brown AT, Fitzgerald R, Zhang X, Breckenridge J, Kazi R, Crocker AJ, Stühlinger MC, Lin K, Cooke JP, Eidt JF, Moursi MM. Homocysteine-induced vascular dysregulation is mediated by the NMDA receptor. Vasc Med. 2005 Aug; 10(3):215-23. PMID: 16235775.
      View in: PubMed
    34. Chen H, Fitzgerald R, Brown AT, Qureshi I, Breckenridge J, Kazi R, Wang Y, Wu Y, Zhang X, Mukunyadzi P, Eidt J, Moursi MM. Identification of a homocysteine receptor in the peripheral endothelium and its role in proliferation. J Vasc Surg. 2005 May; 41(5):853-60. PMID: 15886671.
      View in: PubMed
    35. Bledsoe SL, Brown AT, Davis JA, Chen H, Eidt JF, Moursi MM. Effect of clopidogrel on platelet aggregation and intimal hyperplasia following carotid endarterectomy in the rat. Vascular. 2005 Jan-Feb; 13(1):43-9. PMID: 15895674.
      View in: PubMed
    36. Davis JA, Brown AT, Alshafie T, Poirier LA, Cruz CP, Wang Y, Eidt JF, Moursi MM. Saratin (an inhibitor of platelet-collagen interaction) decreases platelet aggregation and homocysteine-mediated postcarotid endarterectomy intimal hyperplasia in a dose-dependent manner. Am J Surg. 2004 Dec; 188(6):778-85. PMID: 15619499.
      View in: PubMed
    37. Brown AT, Chen H, Davis JA, Qureshi I, Cruz CP, Poirier LA, Eidt JF, Moursi MM. Plasma homocysteine measurements after carotid artery manipulation and clamping in a rat CEA model. J Vasc Surg. 2004 Oct; 40(4):796-802. PMID: 15472610.
      View in: PubMed
    38. Davis JA, Brown AT, Chen H, Wang Y, Poirier LA, Eidt JF, Cruz CP, Moursi MM. Cigarette smoke increases intimal hyperplasia and homocysteine in a rat carotid endarterectomy. J Surg Res. 2004 Sep; 121(1):69-75. PMID: 15313378.
      View in: PubMed
    39. Cruz CP, Eidt JF, Brown AT, Moursi M. Correlation between preoperative and postoperative duplex vein measurements of the greater saphenous vein used for infrainguinal arterial reconstruction. Vasc Endovascular Surg. 2004 Jan-Feb; 38(1):57-62. PMID: 14760478.
      View in: PubMed
    40. Smith TP, Alshafie TA, Cruz CP, Fan CY, Brown AT, Wang Y, Eidt JF, Moursi MM. Saratin, an inhibitor of collagen-platelet interaction, decreases venous anastomotic intimal hyperplasia in a canine dialysis access model. Vasc Endovascular Surg. 2003 Jul-Aug; 37(4):259-69. PMID: 12894368.
      View in: PubMed
    41. Brown AT, Smith TP, Cruz CP, Poirier LA, Simmons D, Williams DK, Wang Y, Eidt JF, Moursi MM. Intimal hyperplasia following carotid endarterectomy in an insulin-resistant rat model. Metabolism. 2003 Jul; 52(7):834-9. PMID: 12870157.
      View in: PubMed
    42. Kern PA, Fishman RB, Song W, Dicker-Brown AT, Fonseca VA. The effect of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) on oxidative enzymes in adipocytes and liver. Toxicology. 2002; 171:117-125.
    43. Fonseca V, Keebler M, Dicker-Brown A, Desouza C, Poirier LA, Murthy SN, McNamara DB. The effect of troglitazone on plasma homocysteine, hepatic and red blood cell S-adenosyl methionine, and S-adenosyl homocysteine and enzymes in homocysteine metabolism in Zucker rats. Metabolism. 2002; 51:783-786.
    44. Cruz CP, Eidt J, Drouilhet J, Brown AT, Wang Y, Barnes CS, Moursi MM. Saratin, an inhibitor of von Willebrand factor-dependent platelet adhesion, decreases platelet aggregation and intimal hyperplasia in a rat carotid endarterectomy model. J Vasc Surg. 2001 Oct; 34(4):724-9. PMID: 11668330.
      View in: PubMed
    45. Southern F, Eidt J, Drouilhet J, Mukunyadzi P, Williams DK, Cruz C, Wang YF, Poirier LA, Brown AT, Moursi MM. Increasing levels of dietary homocystine with carotid endarterectomy produced proportionate increases in plasma homocysteine and intimal hyperplasia. Atherosclerosis. 2001 Sep; 158(1):129-38. PMID: 11500183.
      View in: PubMed
    46. Smith TP, Cruz CP, Brown AT, Eidt JF, Moursi MM. Folate supplementation inhibits intimal hyperplasia induced by a high-homocysteine diet in a rat carotid endarterectomy model. J Vasc Surg. 2001 Sep; 34(3):474-81. PMID: 11533600.
      View in: PubMed
    47. Drouilhet JC, Southern F, Williams DK, Brown AT, Eidt J, Moursi MM. Increased intimal hyperplasia after carotid endarterectomy in spontaneously hypertensive rats. Vasc Surg. 2001 Jan-Feb; 35(1):11-8. PMID: 11668363.
      View in: PubMed
    48. Dicker-Brown AT, Fonseca VA, Fink L, Kern PA. The effect of glucose and insulin on the activity of methylene tetrahydrofolate reductase and cystathionine-B-synthase: studies in hepatocytes. Atherosclerosis. 2001; 158:297-301.
    49. Cruz CP, Eidt JF, Brown AT, Moursi MM. Saratin: (A specific inhibitor of platelet to collagen adhesion) decreases platelet aggregation and neointimal hyperplasia in a rat carotid endarterectomy model. J Vasc Surg. 2001; 34:724-729.
    50. Cao W, McGraw DW, Lee TT, Dicker-Brown A, Hiller FC, Cornett LE, Jones SM. Expression of functional beta 2-adrenergic receptors in a rat airway epithelial cell line (SPOC1) and cell density-dependent induction by glucocorticoids. Exp Lung Res. 2000 Sep; 26(6):421-35. PMID: 11033766.
      View in: PubMed
    51. Fonseca V, Dicker-Brown A, Ranganathan S, Song W, Barnard RJ, Fink L, Kern PA, A BROWN. Effects of a high fat sucrose diet on enzymes of homocysteine metabolism in the rat. Metabolism. 2000; 49:736-741.
    52. Bottje W, Kreider D, Graupner W, Dicker L, Enkvetchakul B. Elevated corticosterone levels following hepatic glutathionine depletion in rats. Med Sci Res. 1992; 20:48.
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