 HSP90 Heat-Shock Proteins
"HSP90 Heat-Shock Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of MOLECULAR CHAPERONES whose members act in the mechanism of SIGNAL TRANSDUCTION by STEROID RECEPTORS.
| Descriptor ID |
D018841
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| MeSH Number(s) |
D12.776.580.216.380
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| Concept/Terms |
HSP90 Heat-Shock Proteins- HSP90 Heat-Shock Proteins
- HSP90 Heat Shock Proteins
- Heat-Shock Proteins, HSP90
- Heat-Shock Proteins 90
- Heat Shock Proteins 90
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Below are MeSH descriptors whose meaning is more general than "HSP90 Heat-Shock Proteins".
Below are MeSH descriptors whose meaning is more specific than "HSP90 Heat-Shock Proteins".
This graph shows the total number of publications written about "HSP90 Heat-Shock Proteins" by people in UAMS Profiles by year, and whether "HSP90 Heat-Shock Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 0 | 1 | 1 | | 2017 | 1 | 2 | 3 | | 2016 | 0 | 1 | 1 | | 2015 | 2 | 1 | 3 | | 2014 | 2 | 1 | 3 | | 2013 | 2 | 1 | 3 | | 2012 | 3 | 0 | 3 | | 2011 | 1 | 1 | 2 | | 2010 | 4 | 1 | 5 | | 2009 | 1 | 0 | 1 | | 2008 | 2 | 2 | 4 | | 2007 | 1 | 2 | 3 | | 2006 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2004 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 1998 | 1 | 1 | 2 | | 1996 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "HSP90 Heat-Shock Proteins" by people in Profiles over the past ten years.
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Fouani M, Basset CA, Mangano GD, Leone LG, Lawand NB, Leone A, Barone R. Heat Shock Proteins Alterations in Rheumatoid Arthritis. Int J Mol Sci. 2022 Mar 03; 23(5).
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Gong Z, Tasset I, Diaz A, Anguiano J, Tas E, Cui L, Kuliawat R, Liu H, Kühn B, Cuervo AM, Muzumdar R. Humanin is an endogenous activator of chaperone-mediated autophagy. J Cell Biol. 2018 02 05; 217(2):635-647.
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Cavenagh J, Oakervee H, Baetiong-Caguioa P, Davies F, Gharibo M, Rabin N, Kurman M, Novak B, Shiraishi N, Nakashima D, Akinaga S, Yong K. A phase I/II study of KW-2478, an Hsp90 inhibitor, in combination with bortezomib in patients with relapsed/refractory multiple myeloma. Br J Cancer. 2017 Oct 24; 117(9):1295-1302.
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Fahmi T, Branch D, Nima ZA, Jang DS, Savenka AV, Biris AS, Basnakian AG. Mechanism of graphene-induced cytotoxicity: Role of endonucleases. J Appl Toxicol. 2017 Nov; 37(11):1325-1332.
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Juvvadi PR, Lee SC, Heitman J, Steinbach WJ. Calcineurin in fungal virulence and drug resistance: Prospects for harnessing targeted inhibition of calcineurin for an antifungal therapeutic approach. Virulence. 2017 02 17; 8(2):186-197.
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Steinbach WJ, Lamoth F, Juvvadi PR. Potential Microbiological Effects of Higher Dosing of Echinocandins. Clin Infect Dis. 2015 Dec 01; 61 Suppl 6:S669-77.
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Lamoth F, Juvvadi PR, Soderblom EJ, Moseley MA, Steinbach WJ. Hsp70 and the Cochaperone StiA (Hop) Orchestrate Hsp90-Mediated Caspofungin Tolerance in Aspergillus fumigatus. Antimicrob Agents Chemother. 2015 Aug; 59(8):4727-33.
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Lamoth F, Alexander BD, Juvvadi PR, Steinbach WJ. Antifungal activity of compounds targeting the Hsp90-calcineurin pathway against various mould species. J Antimicrob Chemother. 2015 May; 70(5):1408-11.
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Lamoth F, Juvvadi PR, Steinbach WJ. Heat shock protein 90 (Hsp90): A novel antifungal target against Aspergillus fumigatus. Crit Rev Microbiol. 2016; 42(2):310-21.
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Zhang L, Fok JH, Davies FE. Heat shock proteins in multiple myeloma. Oncotarget. 2014 Mar 15; 5(5):1132-48.
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Lamoth F, Juvvadi PR, Soderblom EJ, Moseley MA, Asfaw YG, Steinbach WJ. Identification of a key lysine residue in heat shock protein 90 required for azole and echinocandin resistance in Aspergillus fumigatus. Antimicrob Agents Chemother. 2014; 58(4):1889-96.
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Lamoth F, Juvvadi PR, Gehrke C, Asfaw YG, Steinbach WJ. Transcriptional activation of heat shock protein 90 mediated via a proximal promoter region as trigger of caspofungin resistance in Aspergillus fumigatus. J Infect Dis. 2014 Feb 01; 209(3):473-81.
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Shaaban KA, Wang X, Elshahawi SI, Ponomareva LV, Sunkara M, Copley GC, Hower JC, Morris AJ, Kharel MK, Thorson JS. Herbimycins D-F, ansamycin analogues from Streptomyces sp. RM-7-15. J Nat Prod. 2013 Sep 27; 76(9):1619-26.
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Franco MC, Ye Y, Refakis CA, Feldman JL, Stokes AL, Basso M, Melero Fernández de Mera RM, Sparrow NA, Calingasan NY, Kiaei M, Rhoads TW, Ma TC, Grumet M, Barnes S, Beal MF, Beckman JS, Mehl R, Estévez AG. Nitration of Hsp90 induces cell death. Proc Natl Acad Sci U S A. 2013 Mar 19; 110(12):E1102-11.
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Lamoth F, Juvvadi PR, Gehrke C, Steinbach WJ. In vitro activity of calcineurin and heat shock protein 90 Inhibitors against Aspergillus fumigatus azole- and echinocandin-resistant strains. Antimicrob Agents Chemother. 2013 Feb; 57(2):1035-9.
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Martins AS, Davies FE, Workman P. Inhibiting the molecular evolution of cancer through HSP90. Oncotarget. 2012 Oct; 3(10):1054-6.
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Lamoth F, Juvvadi PR, Fortwendel JR, Steinbach WJ. Heat shock protein 90 is required for conidiation and cell wall integrity in Aspergillus fumigatus. Eukaryot Cell. 2012 Nov; 11(11):1324-32.
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