Sequence Alignment
"Sequence Alignment" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.
Descriptor ID |
D016415
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MeSH Number(s) |
E05.393.751
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Concept/Terms |
Sequence Alignment- Sequence Alignment
- Alignment, Sequence
- Alignments, Sequence
- Sequence Alignments
Determination, Sequence Homology- Determination, Sequence Homology
- Determinations, Sequence Homology
- Sequence Homology Determinations
- Sequence Homology Determination
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Below are MeSH descriptors whose meaning is more general than "Sequence Alignment".
Below are MeSH descriptors whose meaning is more specific than "Sequence Alignment".
This graph shows the total number of publications written about "Sequence Alignment" by people in UAMS Profiles by year, and whether "Sequence Alignment" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2018 | 0 | 2 | 2 | 2017 | 0 | 3 | 3 | 2015 | 0 | 5 | 5 | 2014 | 0 | 6 | 6 | 2013 | 1 | 5 | 6 | 2012 | 0 | 3 | 3 | 2011 | 0 | 4 | 4 | 2010 | 1 | 1 | 2 | 2009 | 0 | 11 | 11 | 2008 | 1 | 6 | 7 | 2007 | 0 | 7 | 7 | 2006 | 0 | 4 | 4 | 2005 | 0 | 6 | 6 | 2004 | 2 | 8 | 10 | 2003 | 0 | 6 | 6 | 2002 | 0 | 4 | 4 | 2001 | 0 | 3 | 3 | 2000 | 0 | 3 | 3 | 1998 | 0 | 3 | 3 | 1997 | 0 | 4 | 4 | 1996 | 0 | 4 | 4 | 1995 | 0 | 1 | 1 | 1994 | 0 | 7 | 7 | 1993 | 0 | 2 | 2 | 1992 | 0 | 1 | 1 | 1991 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sequence Alignment" by people in Profiles over the past ten years.
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Dix SR, Sun R, Harris MJ, Batters SL, Sedelnikova SE, Baker PJ, Thomas MS, Rice DW. TssA from Aeromonas hydrophila: expression, purification and crystallographic studies. Acta Crystallogr F Struct Biol Commun. 2018 Sep 01; 74(Pt 9):578-582.
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Chintapalli SV, Anishkin A, Adams SH. Exploring the entry route of palmitic acid and palmitoylcarnitine into myoglobin. Arch Biochem Biophys. 2018 10 01; 655:56-66.
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Avnir Y, Prachanronarong KL, Zhang Z, Hou S, Peterson EC, Sui J, Zayed H, Kurella VB, McGuire AT, Stamatatos L, Hilbert BJ, Bohn MF, Kowalik TF, Jensen JD, Finberg RW, Wang JP, Goodall M, Jefferis R, Zhu Q, Kurt Yilmaz N, Schiffer CA, Marasco WA. Structural Determination of the Broadly Reactive Anti-IGHV1-69 Anti-idiotypic Antibody G6 and Its Idiotope. Cell Rep. 2017 Dec 12; 21(11):3243-3255.
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Lopez CR, Singh S, Hambarde S, Griffin WC, Gao J, Chib S, Yu Y, Ira G, Raney KD, Kim N. Yeast Sub1 and human PC4 are G-quadruplex binding proteins that suppress genome instability at co-transcriptionally formed G4 DNA. Nucleic Acids Res. 2017 Jun 02; 45(10):5850-5862.
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Thankaswamy-Kosalai S, Sen P, Nookaew I. Evaluation and assessment of read-mapping by multiple next-generation sequencing aligners based on genome-wide characteristics. Genomics. 2017 07; 109(3-4):186-191.
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Gudeta DD, Pollini S, Docquier JD, Bortolaia V, Rossolini GM, Guardabassi L. Biochemical Characterization of CPS-1, a Subclass B3 Metallo-ß-Lactamase from a Chryseobacterium piscium Soil Isolate. Antimicrob Agents Chemother. 2015 Dec 14; 60(3):1869-73.
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Gudeta DD, Bortolaia V, Amos G, Wellington EM, Brandt KK, Poirel L, Nielsen JB, Westh H, Guardabassi L. The Soil Microbiota Harbors a Diversity of Carbapenem-Hydrolyzing ß-Lactamases of Potential Clinical Relevance. Antimicrob Agents Chemother. 2016 01; 60(1):151-60.
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Wampande EM, Hatzios SK, Achan B, Mupere E, Nsereko M, Mayanja HK, Eisenach K, Boom WH, Gagneux S, Joloba ML. A single-nucleotide-polymorphism real-time PCR assay for genotyping of Mycobacterium tuberculosis complex in peri-urban Kampala. BMC Infect Dis. 2015 Sep 30; 15:396.
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Tanaka AJ, Cho MT, Millan F, Juusola J, Retterer K, Joshi C, Niyazov D, Garnica A, Gratz E, Deardorff M, Wilkins A, Ortiz-Gonzalez X, Mathews K, Panzer K, Brilstra E, van Gassen KL, Volker-Touw CM, van Binsbergen E, Sobreira N, Hamosh A, McKnight D, Monaghan KG, Chung WK. Mutations in SPATA5 Are Associated with Microcephaly, Intellectual Disability, Seizures, and Hearing Loss. Am J Hum Genet. 2015 Sep 03; 97(3):457-64.
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Griffith M, Griffith OL, Smith SM, Ramu A, Callaway MB, Brummett AM, Kiwala MJ, Coffman AC, Regier AA, Oberkfell BJ, Sanderson GE, Mooney TP, Nutter NG, Belter EA, Du F, Long RL, Abbott TE, Ferguson IT, Morton DL, Burnett MM, Weible JV, Peck JB, Dukes A, McMichael JF, Lolofie JT, Derickson BR, Hundal J, Skidmore ZL, Ainscough BJ, Dees ND, Schierding WS, Kandoth C, Kim KH, Lu C, Harris CC, Maher N, Maher CA, Magrini VJ, Abbott BS, Chen K, Clark E, Das I, Fan X, Hawkins AE, Hepler TG, Wylie TN, Leonard SM, Schroeder WE, Shi X, Carmichael LK, Weil MR, Wohlstadter RW, Stiehr G, McLellan MD, Pohl CS, Miller CA, Koboldt DC, Walker JR, Eldred JM, Larson DE, Dooling DJ, Ding L, Mardis ER, Wilson RK. Genome Modeling System: A Knowledge Management Platform for Genomics. PLoS Comput Biol. 2015 Jul; 11(7):e1004274.
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He Y, Zhang F, Flaherty P. RVD2: an ultra-sensitive variant detection model for low-depth heterogeneous next-generation sequencing data. Bioinformatics. 2015 Sep 01; 31(17):2785-93.
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Yu D, Green B, Marrone A, Guo Y, Kadlubar S, Lin D, Fuscoe J, Pogribny I, Ning B. Suppression of CYP2C9 by microRNA hsa-miR-128-3p in human liver cells and association with hepatocellular carcinoma. Sci Rep. 2015 Feb 23; 5:8534.
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Yaryura PM, Conforte VP, Malamud F, Roeschlin R, de Pino V, Castagnaro AP, McCarthy Y, Dow JM, Marano MR, Vojnov AA. XbmR, a new transcription factor involved in the regulation of chemotaxis, biofilm formation and virulence in Xanthomonas citri subsp. citri. Environ Microbiol. 2015 Nov; 17(11):4164-76.
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Lindy AS, Parekh PK, Zhu R, Kanju P, Chintapalli SV, Tsvilovskyy V, Patterson RL, Anishkin A, van Rossum DB, Liedtke WB. TRPV channel-mediated calcium transients in nociceptor neurons are dispensable for avoidance behaviour. Nat Commun. 2014 Sep 02; 5:4734.
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Papazyan R, Voronina E, Chapman JR, Luperchio TR, Gilbert TM, Meier E, Mackintosh SG, Shabanowitz J, Tackett AJ, Reddy KL, Coyne RS, Hunt DF, Liu Y, Taverna SD. Methylation of histone H3K23 blocks DNA damage in pericentric heterochromatin during meiosis. Elife. 2014 Aug 26; 3:e02996.
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Saha S, Pashov A, Siegel ER, Murali R, Kieber-Emmons T. Defining the recognition elements of Lewis Y-reactive antibodies. PLoS One. 2014; 9(8):e104208.
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Gilbert TM, McDaniel SL, Byrum SD, Cades JA, Dancy BC, Wade H, Tackett AJ, Strahl BD, Taverna SD. A PWWP domain-containing protein targets the NuA3 acetyltransferase complex via histone H3 lysine 36 trimethylation to coordinate transcriptional elongation at coding regions. Mol Cell Proteomics. 2014 Nov; 13(11):2883-95.
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Adedeji AO, Singh K, Kassim A, Coleman CM, Elliott R, Weiss SR, Frieman MB, Sarafianos SG. Evaluation of SSYA10-001 as a replication inhibitor of severe acute respiratory syndrome, mouse hepatitis, and Middle East respiratory syndrome coronaviruses. Antimicrob Agents Chemother. 2014 Aug; 58(8):4894-8.
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Stebbing RE, Irvin SC, Rivera-Serrano EE, Boehme KW, Ikizler M, Yoder JA, Dermody TS, Sherry B. An ITAM in a nonenveloped virus regulates activation of NF-?B, induction of beta interferon, and viral spread. J Virol. 2014 Mar; 88(5):2572-83.
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Bellini D, Caly DL, McCarthy Y, Bumann M, An SQ, Dow JM, Ryan RP, Walsh MA. Crystal structure of an HD-GYP domain cyclic-di-GMP phosphodiesterase reveals an enzyme with a novel trinuclear catalytic iron centre. Mol Microbiol. 2014 Jan; 91(1):26-38.
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Graham JW, Lei MG, Lee CY. Trapping and identification of cellular substrates of the Staphylococcus aureus ClpC chaperone. J Bacteriol. 2013 Oct; 195(19):4506-16.
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Lemos de Matos A, Liu J, McFadden G, Esteves PJ. Evolution and divergence of the mammalian SAMD9/SAMD9L gene family. BMC Evol Biol. 2013 Jun 12; 13:121.
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Roy A, Taddese B, Vohra S, Thimmaraju PK, Illingworth CJ, Simpson LM, Mukherjee K, Reynolds CA, Chintapalli SV. Identifying subset errors in multiple sequence alignments. J Biomol Struct Dyn. 2014; 32(3):364-71.
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Ashby C, Johnson D, Walker K, Kanj IA, Xia G, Huang X. New enumeration algorithm for protein structure comparison and classification. BMC Genomics. 2013; 14 Suppl 2:S1.
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Kaas RS, Friis C, Ussery DW, Aarestrup FM. Estimating variation within the genes and inferring the phylogeny of 186 sequenced diverse Escherichia coli genomes. BMC Genomics. 2012 Oct 31; 13:577.
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Al Rayyan N, Wankhade UD, Bush K, Good DJ. Two single nucleotide polymorphisms in the human nescient helix-loop-helix 2 (NHLH2) gene reduce mRNA stability and DNA binding. Gene. 2013 Jan 01; 512(1):134-42.
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He X, Byrd AK, Yun MK, Pemble CW, Harrison D, Yeruva L, Dahl C, Kreuzer KN, Raney KD, White SW. The T4 phage SF1B helicase Dda is structurally optimized to perform DNA strand separation. Structure. 2012 Jul 03; 20(7):1189-200.
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Papadopoulou A, Anastasiou I, Spagopoulou F, Stalimerou M, Terzopoulou S, Legakis A, Vogler AP. Testing the species--genetic diversity correlation in the Aegean archipelago: toward a haplotype-based macroecology? Am Nat. 2011 Aug; 178(2):241-55.
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Kumar AK, Yennawar NH, Yennawar HP, Ferry JG. Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a novel plant-type ferredoxin/thioredoxin reductase-like protein from Methanosarcina acetivorans. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Jul 01; 67(Pt 7):775-8.
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Hong Y, Chintapalli SV, Ko KD, Bhardwaj G, Zhang Z, van Rossum D, Patterson RL. Predicting protein folds with fold-specific PSSM libraries. PLoS One. 2011; 6(6):e20557.
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Gokulan K, Aggarwal A, Shipman L, Besra GS, Sacchettini JC. Mycobacterium tuberculosis acyl carrier protein synthase adopts two different pH-dependent structural conformations. Acta Crystallogr D Biol Crystallogr. 2011 Jul; 67(Pt 7):657-69.
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Han Q, Aligo J, Manna D, Belton K, Chintapalli SV, Hong Y, Patterson RL, van Rossum DB, Konan KV. Conserved GXXXG- and S/T-like motifs in the transmembrane domains of NS4B protein are required for hepatitis C virus replication. J Virol. 2011 Jul; 85(13):6464-79.
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