 Viral Nonstructural Proteins
"Viral Nonstructural Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins encoded by a VIRAL GENOME that are produced in the organisms they infect, but not packaged into the VIRUS PARTICLES. Some of these proteins may play roles within the infected cell during VIRUS REPLICATION or act in regulation of virus replication or VIRUS ASSEMBLY.
| Descriptor ID |
D017361
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| MeSH Number(s) |
D12.776.964.900
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| Concept/Terms |
Viral Nonstructural Proteins- Viral Nonstructural Proteins
- Proteins, Viral Nonstructural
- NS Proteins, Viral
- Proteins, Viral NS
- Viral Nonstructural Protein
- Nonstructural Protein, Viral
- Protein, Viral Nonstructural
- Viral NS Proteins
- Nonstructural Proteins, Viral
- Viral Non-Structural Proteins
- Non-Structural Proteins, Viral
- Proteins, Viral Non-Structural
- Viral Non Structural Proteins
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Below are MeSH descriptors whose meaning is more general than "Viral Nonstructural Proteins".
Below are MeSH descriptors whose meaning is more specific than "Viral Nonstructural Proteins".
This graph shows the total number of publications written about "Viral Nonstructural Proteins" by people in UAMS Profiles by year, and whether "Viral Nonstructural Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 0 | 1 | 1 | | 2018 | 2 | 0 | 2 | | 2015 | 1 | 1 | 2 | | 2013 | 1 | 1 | 2 | | 2012 | 1 | 1 | 2 | | 2011 | 1 | 0 | 1 | | 2010 | 5 | 1 | 6 | | 2009 | 2 | 0 | 2 | | 2008 | 3 | 0 | 3 | | 2005 | 3 | 0 | 3 | | 2004 | 2 | 0 | 2 | | 2003 | 2 | 0 | 2 | | 2002 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Viral Nonstructural Proteins" by people in Profiles over the past ten years.
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Carossino M, Barrandeguy ME, Erol E, Li Y, Balasuriya UBR. Development and evaluation of a one-step multiplex real-time TaqMan® RT-qPCR assay for the detection and genotyping of equine G3 and G14 rotaviruses in fecal samples. Virol J. 2019 04 25; 16(1):49.
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Marecki JC, Aarattuthodiyil S, Byrd AK, Penthala NR, Crooks PA, Raney KD. N-Naphthoyl-substituted indole thio-barbituric acid analogs inhibit the helicase activity of the hepatitis C virus NS3. Bioorg Med Chem Lett. 2019 02 01; 29(3):430-434.
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Phillips MB, Stuart JD, Simon EJ, Boehme KW. Nonstructural Protein s1s Is Required for Optimal Reovirus Protein Expression. J Virol. 2018 04 01; 92(7).
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Taylor JK, Coleman CM, Postel S, Sisk JM, Bernbaum JG, Venkataraman T, Sundberg EJ, Frieman MB. Severe Acute Respiratory Syndrome Coronavirus ORF7a Inhibits Bone Marrow Stromal Antigen 2 Virion Tethering through a Novel Mechanism of Glycosylation Interference. J Virol. 2015 Dec; 89(23):11820-33.
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Reynolds KA, Cameron CE, Raney KD. Melting of Duplex DNA in the Absence of ATP by the NS3 Helicase Domain through Specific Interaction with a Single-Strand/Double-Strand Junction. Biochemistry. 2015 Jul 14; 54(27):4248-58.
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Liu S, Chen R, Hagedorn CH. Direct visualization of hepatitis C virus-infected Huh7.5 cells with a high titre of infectious chimeric JFH1-EGFP reporter virus in three-dimensional Matrigel cell cultures. J Gen Virol. 2014 Feb; 95(Pt 2):423-33.
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Boehme KW, Hammer K, Tollefson WC, Konopka-Anstadt JL, Kobayashi T, Dermody TS. Nonstructural protein s1s mediates reovirus-induced cell cycle arrest and apoptosis. J Virol. 2013 Dec; 87(23):12967-79.
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Liu S, Xiao L, Nelson C, Hagedorn CH, Hagedorn C. A cell culture adapted HCV JFH1 variant that increases viral titers and permits the production of high titer infectious chimeric reporter viruses. PLoS One. 2012; 7(9):e44965.
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Cao J, Zhang X. Comparative in vivo analysis of the nsp15 endoribonuclease of murine, porcine and severe acute respiratory syndrome coronaviruses. Virus Res. 2012 Aug; 167(2):247-58.
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Han Q, Aligo J, Manna D, Belton K, Chintapalli SV, Hong Y, Patterson RL, van Rossum DB, Konan KV. Conserved GXXXG- and S/T-like motifs in the transmembrane domains of NS4B protein are required for hepatitis C virus replication. J Virol. 2011 Jul; 85(13):6464-79.
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Trask SD, Taraporewala ZF, Boehme KW, Dermody TS, Patton JT. Dual selection mechanisms drive efficient single-gene reverse genetics for rotavirus. Proc Natl Acad Sci U S A. 2010 Oct 26; 107(43):18652-7.
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Hwang J, Huang L, Cordek DG, Vaughan R, Reynolds SL, Kihara G, Raney KD, Kao CC, Cameron CE. Hepatitis C virus nonstructural protein 5A: biochemical characterization of a novel structural class of RNA-binding proteins. J Virol. 2010 Dec; 84(24):12480-91.
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Harrus D, Ahmed-El-Sayed N, Simister PC, Miller S, Triconnet M, Hagedorn CH, Mahias K, Rey FA, Astier-Gin T, Bressanelli S. Further insights into the roles of GTP and the C terminus of the hepatitis C virus polymerase in the initiation of RNA synthesis. J Biol Chem. 2010 Oct 22; 285(43):32906-18.
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Raney KD, Sharma SD, Moustafa IM, Cameron CE. Hepatitis C virus non-structural protein 3 (HCV NS3): a multifunctional antiviral target. J Biol Chem. 2010 Jul 23; 285(30):22725-31.
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Brown RA, Gralewski JH, Eid AJ, Knoll BM, Finberg RW, Razonable RR. R753Q single-nucleotide polymorphism impairs toll-like receptor 2 recognition of hepatitis C virus core and nonstructural 3 proteins. Transplantation. 2010 Apr 15; 89(7):811-5.
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Matlock DL, Yeruva L, Byrd AK, Mackintosh SG, Langston C, Brown C, Cameron CE, Fischer CJ, Raney KD. Investigation of translocation, DNA unwinding, and protein displacement by NS3h, the helicase domain from the hepatitis C virus helicase. Biochemistry. 2010 Mar 16; 49(10):2097-109.
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