 Herpesvirus 8, Human
"Herpesvirus 8, Human" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A species in the genus RHADINOVIRUS, subfamily GAMMAHERPESVIRINAE, isolated from patients with AIDS-related and "classical" Kaposi sarcoma.
| Descriptor ID |
D019288
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| MeSH Number(s) |
B04.280.382.400.700.330 B04.909.204.210.400.700.330 B04.909.204.382.400.700.330 B04.909.574.204.500.700.330
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| Concept/Terms |
Herpesvirus 8, Human- Herpesvirus 8, Human
- Herpesvirus, Kaposi's Sarcoma-Associated
- Herpesvirus, Kaposi's Sarcoma Associated
- Herpesvirus, Kaposis Sarcoma-Associated
- Herpesviruses, Kaposi's Sarcoma-Associated
- Kaposi's Sarcoma-Associated Herpesviruses
- Sarcoma-Associated Herpesviruses, Kaposi's
- KSHV
- Human herpesvirus 8
- Kaposi Sarcoma-Associated Herpesvirus
- Kaposi Sarcoma Associated Herpesvirus
- Kaposi's Sarcoma-Associated Herpesvirus
- Kaposi's Sarcoma Associated Herpesvirus
- Kaposis Sarcoma-Associated Herpesvirus
- Herpesvirus, Kaposi Sarcoma-Associated
- Herpesvirus, Kaposi Sarcoma Associated
- Sarcoma-Associated Herpesvirus, Kaposi
- HHV-8
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Below are MeSH descriptors whose meaning is more general than "Herpesvirus 8, Human".
Below are MeSH descriptors whose meaning is more specific than "Herpesvirus 8, Human".
This graph shows the total number of publications written about "Herpesvirus 8, Human" by people in UAMS Profiles by year, and whether "Herpesvirus 8, Human" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2022 | 1 | 0 | 1 | | 2021 | 3 | 0 | 3 | | 2020 | 5 | 2 | 7 | | 2019 | 5 | 1 | 6 | | 2018 | 1 | 1 | 2 | | 2017 | 6 | 1 | 7 | | 2016 | 3 | 2 | 5 | | 2015 | 2 | 2 | 4 | | 2014 | 6 | 1 | 7 | | 2013 | 2 | 1 | 3 | | 2012 | 1 | 0 | 1 | | 2011 | 3 | 0 | 3 | | 2010 | 4 | 1 | 5 | | 2009 | 0 | 1 | 1 | | 2008 | 2 | 1 | 3 | | 2006 | 1 | 0 | 1 | | 2005 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 1997 | 2 | 0 | 2 |
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Below are the most recent publications written about "Herpesvirus 8, Human" by people in Profiles over the past ten years.
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Chen J, Dai L, Kendrick S, Post SR, Qin Z. The Anti-COVID-19 Drug Remdesivir Promotes Oncogenic Herpesvirus Reactivation through Regulation of Intracellular Signaling Pathways. Antimicrob Agents Chemother. 2022 03 15; 66(3):e0239521.
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Pierson SK, Shenoy S, Oromendia AB, Gorzewski AM, Langan Pai RA, Nabel CS, Ruth JR, Parente SAT, Arenas DJ, Guilfoyle M, Reddy M, Weinblatt M, Shadick N, Bower M, Pria AD, Masaki Y, Katz L, Mezey J, Beineke P, Lee D, Tendler C, Kambayashi T, Fosså A, van Rhee F, Fajgenbaum DC. Discovery and validation of a novel subgroup and therapeutic target in idiopathic multicentric Castleman disease. Blood Adv. 2021 09 14; 5(17):3445-3456.
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Chen J, Dai L, Barrett L, James J, Plaisance-Bonstaff K, Post SR, Qin Z. SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus. Commun Biol. 2021 06 03; 4(1):682.
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Barrett L, Dai L, Wang S, Qin Z. Kaposi's sarcoma-associated herpesvirus and extracellular vesicles. J Med Virol. 2021 06; 93(6):3294-3299.
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van Rhee F, Oksenhendler E, Srkalovic G, Voorhees P, Lim M, Dispenzieri A, Ide M, Parente S, Schey S, Streetly M, Wong R, Wu D, Maillard I, Brandstadter J, Munshi N, Bowne W, Elenitoba-Johnson KS, Fössa A, Lechowicz MJ, Chandrakasan S, Pierson SK, Greenway A, Nasta S, Yoshizaki K, Kurzrock R, Uldrick TS, Casper C, Chadburn A, Fajgenbaum DC. International evidence-based consensus diagnostic and treatment guidelines for unicentric Castleman disease. Blood Adv. 2020 12 08; 4(23):6039-6050.
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Chen J, Goyal N, Dai L, Lin Z, Del Valle L, Zabaleta J, Liu J, Post SR, Foroozesh M, Qin Z. Developing new ceramide analogs and identifying novel sphingolipid-controlled genes against a virus-associated lymphoma. Blood. 2020 11 05; 136(19):2175-2187.
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Barrett L, Chen J, Dai L, Plaisance-Bonstaff K, Del Valle L, Qin Z. Role of Interleukin-1 Family Members and Signaling Pathways in KSHV Pathogenesis. Front Cell Infect Microbiol. 2020; 10:587929.
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Liang Z, Qin Z, Riker AI, Xi Y. CRISPR/Cas9 ablating viral microRNA promotes lytic reactivation of Kaposi's sarcoma-associated herpesvirus. Biochem Biophys Res Commun. 2020 12 17; 533(4):1400-1405.
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Ramos JC, Sparano JA, Chadburn A, Reid EG, Ambinder RF, Siegel ER, Moore PC, Rubinstein PG, Durand CM, Cesarman E, Aboulafia D, Baiocchi R, Ratner L, Kaplan L, Capoferri AA, Lee JY, Mitsuyasu R, Noy A. Impact of Myc in HIV-associated non-Hodgkin lymphomas treated with EPOCH and outcomes with vorinostat (AMC-075 trial). Blood. 2020 09 10; 136(11):1284-1297.
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Dai L, Jung BG, Chen J, Samten B, Forrest JC, Post SR, Qin Z. The potential impacts of early secreted antigenic target of 6?kDa of Mycobacterium tuberculosis on KSHV-infected cells. J Med Virol. 2021 06; 93(6):4028-4032.
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Dai L, Qiao J, Yin J, Goldstein A, Lin HY, Post SR, Qin Z. Kaposi Sarcoma-Associated Herpesvirus and Staphylococcus aureus Coinfection in Oral Cavities of HIV-Positive Patients: A Unique Niche for Oncogenic Virus Lytic Reactivation. J Infect Dis. 2020 03 28; 221(8):1331-1341.
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Morrison K, Manzano M, Chung K, Schipma MJ, Bartom ET, Gottwein E. The Oncogenic Kaposi's Sarcoma-Associated Herpesvirus Encodes a Mimic of the Tumor-Suppressive miR-15/16 miRNA Family. Cell Rep. 2019 12 03; 29(10):2961-2969.e6.
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Chen J, Dai L, Goldstein A, Zhang H, Tang W, Forrest JC, Post SR, Chen X, Qin Z. Identification of new antiviral agents against Kaposi's sarcoma-associated herpesvirus (KSHV) by high-throughput drug screening reveals the role of histamine-related signaling in promoting viral lytic reactivation. PLoS Pathog. 2019 12; 15(12):e1008156.
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Reid EG, Suazo A, Lensing SY, Dittmer DP, Ambinder RF, Maldarelli F, Gorelick RJ, Aboulafia D, Mitsuyasu R, Dickson MA, Wachsman W. Pilot Trial AMC-063: Safety and Efficacy of Bortezomib in AIDS-associated Kaposi Sarcoma. Clin Cancer Res. 2020 02 01; 26(3):558-565.
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Chen J, Del Valle L, Lin HY, Plaisance-Bonstaff K, Forrest JC, Post SR, Qin Z. Expression of PD-1 and PD-Ls in Kaposi's sarcoma and regulation by oncogenic herpesvirus lytic reactivation. Virology. 2019 10; 536:16-19.
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Nabel CS, Sameroff S, Shilling D, Alapat D, Ruth JR, Kawano M, Sato Y, Stone K, Spetalen S, Valdivieso F, Feldman MD, Chadburn A, Fosså A, van Rhee F, Lipkin WI, Fajgenbaum DC. Virome capture sequencing does not identify active viral infection in unicentric and idiopathic multicentric Castleman disease. PLoS One. 2019; 14(6):e0218660.
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Sopfe J, Endres A, Campbell K, Hayes K, Trout AT, Liang X, Lorsbach R, O'Brien MM, Cost CR. Castleman disease in pediatrics: Insights on presentation, treatment, and outcomes from a two-site retrospective cohort study. Pediatr Blood Cancer. 2019 05; 66(5):e27613.
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Manzano M, Patil A, Waldrop A, Dave SS, Behdad A, Gottwein E. Gene essentiality landscape and druggable oncogenic dependencies in herpesviral primary effusion lymphoma. Nat Commun. 2018 08 15; 9(1):3263.
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Qiao J, Cao Y, Zabaleta J, Yang L, Dai L, Qin Z. Regulation of Virus-Associated Lymphoma Growth and Gene Expression by Bacterial Quorum-Sensing Molecules. J Virol. 2018 07 15; 92(14).
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Dai L, Lin Z, Jiang W, Flemington EK, Qin Z. Lipids, lipid metabolism and Kaposi's sarcoma-associated herpesvirus pathogenesis. Virol Sin. 2017 Oct; 32(5):369-375.
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Dai L, Bai A, Smith CD, Rodriguez PC, Yu F, Qin Z. ABC294640, A Novel Sphingosine Kinase 2 Inhibitor, Induces Oncogenic Virus-Infected Cell Autophagic Death and Represses Tumor Growth. Mol Cancer Ther. 2017 Dec; 16(12):2724-2734.
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Gupta A, Oldenburg DG, Salinas E, White DW, Forrest JC. Murine Gammaherpesvirus 68 Expressing Kaposi Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen (LANA) Reveals both Functional Conservation and Divergence in LANA Homologs. J Virol. 2017 10 01; 91(19).
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Dai L, Cao Y, Jiang W, Zabaleta J, Liu Z, Qiao J, Qin Z. KSHV co-infection down-regulates HPV16 E6 and E7 from cervical cancer cells. Oncotarget. 2017 May 30; 8(22):35792-35803.
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Lam BQ, Dai L, Li L, Qiao J, Lin Z, Qin Z. Molecular mechanisms of activating c-MET in KSHV+ primary effusion lymphoma. Oncotarget. 2017 Mar 14; 8(11):18373-18380.
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Cao Y, Qiao J, Lin Z, Zabaleta J, Dai L, Qin Z. Up-regulation of tumor suppressor genes by exogenous dhC16-Cer contributes to its anti-cancer activity in primary effusion lymphoma. Oncotarget. 2017 Feb 28; 8(9):15220-15229.
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Fajgenbaum DC, Uldrick TS, Bagg A, Frank D, Wu D, Srkalovic G, Simpson D, Liu AY, Menke D, Chandrakasan S, Lechowicz MJ, Wong RS, Pierson S, Paessler M, Rossi JF, Ide M, Ruth J, Croglio M, Suarez A, Krymskaya V, Chadburn A, Colleoni G, Nasta S, Jayanthan R, Nabel CS, Casper C, Dispenzieri A, Fosså A, Kelleher D, Kurzrock R, Voorhees P, Dogan A, Yoshizaki K, van Rhee F, Oksenhendler E, Jaffe ES, Elenitoba-Johnson KS, Lim MS. International, evidence-based consensus diagnostic criteria for HHV-8-negative/idiopathic multicentric Castleman disease. Blood. 2017 Mar 23; 129(12):1646-1657.
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Dai L, Bai L, Lin Z, Qiao J, Yang L, Flemington EK, Zabaleta J, Qin Z. Transcriptomic analysis of KSHV-infected primary oral fibroblasts: The role of interferon-induced genes in the latency of oncogenic virus. Oncotarget. 2016 Jul 26; 7(30):47052-47060.
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Bender Ignacio RA, Lee JY, Rudek MA, Dittmer DP, Ambinder RF, Krown SE. Brief Report: A Phase 1b/Pharmacokinetic Trial of PTC299, a Novel PostTranscriptional VEGF Inhibitor, for AIDS-Related Kaposi's Sarcoma: AIDS Malignancy Consortium Trial 059. J Acquir Immune Defic Syndr. 2016 May 01; 72(1):52-7.
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Liu AY, Nabel CS, Finkelman BS, Ruth JR, Kurzrock R, van Rhee F, Krymskaya VP, Kelleher D, Rubenstein AH, Fajgenbaum DC. Idiopathic multicentric Castleman's disease: a systematic literature review. Lancet Haematol. 2016 Apr; 3(4):e163-75.
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Dai L, Qiao J, Nguyen D, Struckhoff AP, Doyle L, Bonstaff K, Del Valle L, Parsons C, Toole BP, Renne R, Qin Z. Role of heme oxygenase-1 in the pathogenesis and tumorigenicity of Kaposi's sarcoma-associated herpesvirus. Oncotarget. 2016 Mar 01; 7(9):10459-71.
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Dai L, Trillo-Tinoco J, Chen Y, Bonstaff K, Del Valle L, Parsons C, Ochoa AC, Zabaleta J, Toole BP, Qin Z. CD147 and downstream ADAMTSs promote the tumorigenicity of Kaposi's sarcoma-associated herpesvirus infected endothelial cells. Oncotarget. 2016 Jan 26; 7(4):3806-18.
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Dai L, Trillo-Tinoco J, Cao Y, Bonstaff K, Doyle L, Del Valle L, Whitby D, Parsons C, Reiss K, Zabaleta J, Qin Z. Targeting HGF/c-MET induces cell cycle arrest, DNA damage, and apoptosis for primary effusion lymphoma. Blood. 2015 Dec 24; 126(26):2821-31.
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Manzano M, Forte E, Raja AN, Schipma MJ, Gottwein E. Divergent target recognition by coexpressed 5'-isomiRs of miR-142-3p and selective viral mimicry. RNA. 2015 Sep; 21(9):1606-20.
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Dai L, Cao Y, Chen Y, Kaleeba JA, Zabaleta J, Qin Z. Genomic analysis of xCT-mediated regulatory network: Identification of novel targets against AIDS-associated lymphoma. Oncotarget. 2015 May 20; 6(14):12710-22.
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Dai L, Chen Y, Bonstaff K, Doyle L, Toole B, Parsons C, Qin Z. Induction of hyaluronan production by oncogenic KSHV and the contribution to viral pathogenesis in AIDS patients. Cancer Lett. 2015 Jul 01; 362(2):158-66.
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Forte E, Raja AN, Shamulailatpam P, Manzano M, Schipma MJ, Casey JL, Gottwein E. MicroRNA-mediated transformation by the Kaposi's sarcoma-associated herpesvirus Kaposin locus. J Virol. 2015 Feb; 89(4):2333-41.
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Qin Z, Peruzzi F, Reiss K, Dai L. Role of host microRNAs in Kaposi's sarcoma-associated herpesvirus pathogenesis. Viruses. 2014 Nov 21; 6(11):4571-80.
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Dai L, Plaisance-Bonstaff K, Voelkel-Johnson C, Smith CD, Ogretmen B, Qin Z, Parsons C. Sphingosine kinase-2 maintains viral latency and survival for KSHV-infected endothelial cells. PLoS One. 2014; 9(7):e102314.
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Dai L, DeFee MR, Cao Y, Wen J, Wen X, Noverr MC, Qin Z. Lipoteichoic acid (LTA) and lipopolysaccharides (LPS) from periodontal pathogenic bacteria facilitate oncogenic herpesvirus infection within primary oral cells. PLoS One. 2014; 9(6):e101326.
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Dai L, Cao Y, Chen Y, Parsons C, Qin Z. Targeting xCT, a cystine-glutamate transporter induces apoptosis and tumor regression for KSHV/HIV-associated lymphoma. J Hematol Oncol. 2014 Apr 04; 7:30.
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Fajgenbaum DC, van Rhee F, Nabel CS. HHV-8-negative, idiopathic multicentric Castleman disease: novel insights into biology, pathogenesis, and therapy. Blood. 2014 May 08; 123(19):2924-33.
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Dai L, Trillo-Tinoco J, Bai L, Kang B, Xu Z, Wen X, Del Valle L, Qin Z. Systematic analysis of a xenograft mice model for KSHV+ primary effusion lymphoma (PEL). PLoS One. 2014; 9(2):e90349.
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Qin Z, Dai L, Trillo-Tinoco J, Senkal C, Wang W, Reske T, Bonstaff K, Del Valle L, Rodriguez P, Flemington E, Voelkel-Johnson C, Smith CD, Ogretmen B, Parsons C. Targeting sphingosine kinase induces apoptosis and tumor regression for KSHV-associated primary effusion lymphoma. Mol Cancer Ther. 2014 Jan; 13(1):154-64.
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Manzano M, Shamulailatpam P, Raja AN, Gottwein E. Kaposi's sarcoma-associated herpesvirus encodes a mimic of cellular miR-23. J Virol. 2013 Nov; 87(21):11821-30.
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Dai L, Bai L, Lu Y, Xu Z, Reiss K, Del Valle L, Kaleeba J, Toole BP, Parsons C, Qin Z. Emmprin and KSHV: new partners in viral cancer pathogenesis. Cancer Lett. 2013 Sep 01; 337(2):161-6.
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Qin Z, Dai L, Defee M, Findlay VJ, Watson DK, Toole BP, Cameron J, Peruzzi F, Kirkwood K, Parsons C. Kaposi's sarcoma-associated herpesvirus suppression of DUSP1 facilitates cellular pathogenesis following de novo infection. J Virol. 2013 Jan; 87(1):621-35.
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