Osteolysis
"Osteolysis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Dissolution of bone that particularly involves the removal or loss of calcium.
Descriptor ID |
D010014
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MeSH Number(s) |
C05.116.264.579 G11.427.590.195.150.570
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Osteolysis".
Below are MeSH descriptors whose meaning is more specific than "Osteolysis".
This graph shows the total number of publications written about "Osteolysis" by people in UAMS Profiles by year, and whether "Osteolysis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2022 | 2 | 0 | 2 | 2021 | 0 | 1 | 1 | 2019 | 1 | 0 | 1 | 2018 | 0 | 2 | 2 | 2017 | 1 | 2 | 3 | 2015 | 2 | 0 | 2 | 2014 | 1 | 2 | 3 | 2013 | 2 | 0 | 2 | 2012 | 1 | 4 | 5 | 2011 | 1 | 0 | 1 | 2010 | 2 | 2 | 4 | 2009 | 1 | 0 | 1 | 2008 | 1 | 0 | 1 | 2006 | 3 | 0 | 3 | 2005 | 1 | 0 | 1 | 2004 | 0 | 1 | 1 | 2003 | 4 | 1 | 5 | 1998 | 1 | 0 | 1 |
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Below are the most recent publications written about "Osteolysis" by people in Profiles over the past ten years.
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Gai D, Chen JR, Stewart JP, Nookaew I, Habelhah H, Ashby C, Sun F, Cheng Y, Li C, Xu H, Peng B, Garg TK, Schinke C, Thanendrarajan S, Zangari M, Chen F, Barlogie B, van Rhee F, Tricot G, Shaughnessy JD, Zhan F. CST6 suppresses osteolytic bone disease in multiple myeloma by blocking osteoclast differentiation. J Clin Invest. 2022 09 15; 132(18).
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Sabol HM, Amorim T, Ashby C, Halladay D, Anderson J, Cregor M, Sweet M, Nookaew I, Kurihara N, Roodman GD, Bellido T, Delgado-Calle J. Notch3 signaling between myeloma cells and osteocytes in the tumor niche promotes tumor growth and bone destruction. Neoplasia. 2022 06; 28:100785.
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Sabol HM, Ferrari AJ, Adhikari M, Amorim T, McAndrews K, Anderson J, Vigolo M, Lehal R, Cregor M, Khan S, Cuevas PL, Helms JA, Kurihara N, Srinivasan V, Ebetino FH, Boeckman RK, Roodman GD, Bellido T, Delgado-Calle J. Targeting Notch Inhibitors to the Myeloma Bone Marrow Niche Decreases Tumor Growth and Bone Destruction without Gut Toxicity. Cancer Res. 2021 10 01; 81(19):5102-5114.
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Sun F, Cheng Y, Walsh SA, Acevedo MR, Jing X, Han SS, Pisano MD, Tomasson MH, Lichtenstein AK, Zhan F, Hari P, Janz S. Osteolytic disease in IL-6 and Myc dependent mouse model of human myeloma. Haematologica. 2020 03; 105(3):e111-e115.
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Stambough JB, Rames RD, Pashos GE, Maloney WJ, Martell JM, Clohisy JC. Conventional Polyethylene in Total Hip Arthroplasty in Young Patients: Survivorship, Wear Analysis, and Clinical Outcomes Between 15 and 20 Years. J Arthroplasty. 2018 12; 33(12):3712-3718.
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Bonutti PM, Mesko JW, Ramakrishnan R. Long-term Wear Data From a Prospective Multicenter Study of Second-Generation Highly Cross-linked Polyethylene Inserts in Total Hip Arthroplasty. Orthopedics. 2018 Jul 01; 41(4):e529-e533.
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Johnson RW, Suva LJ. Hallmarks of Bone Metastasis. Calcif Tissue Int. 2018 02; 102(2):141-151.
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Thummuri D, Naidu VGM, Chaudhari P. Carnosic acid attenuates RANKL-induced oxidative stress and osteoclastogenesis via induction of Nrf2 and suppression of NF-?B and MAPK signalling. J Mol Med (Berl). 2017 10; 95(10):1065-1076.
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Delgado-Calle J, Anderson J, Cregor MD, Condon KW, Kuhstoss SA, Plotkin LI, Bellido T, Roodman GD. Genetic deletion of Sost or pharmacological inhibition of sclerostin prevent multiple myeloma-induced bone disease without affecting tumor growth. Leukemia. 2017 12; 31(12):2686-2694.
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Sinacore DR, Bohnert KL, Smith KE, Hastings MK, Commean PK, Gutekunst DJ, Johnson JE, Prior FW. Persistent inflammation with pedal osteolysis 1year after Charcot neuropathic osteoarthropathy. J Diabetes Complications. 2017 Jun; 31(6):1014-1020.
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Haynes JA, Stambough JB, Sassoon AA, Johnson SR, Clohisy JC, Nunley RM. Contemporary Surgical Indications and Referral Trends in Revision Total Hip Arthroplasty: A 10-Year Review. J Arthroplasty. 2016 Mar; 31(3):622-5.
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Thummuri D, Jeengar MK, Shrivastava S, Nemani H, Ramavat RN, Chaudhari P, Naidu VG. Thymoquinone prevents RANKL-induced osteoclastogenesis activation and osteolysis in an in vivo model of inflammation by suppressing NF-KB and MAPK Signalling. Pharmacol Res. 2015 Sep; 99:63-73.
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Trotter TN, Li M, Pan Q, Peker D, Rowan PD, Li J, Zhan F, Suva LJ, Javed A, Yang Y. Myeloma cell-derived Runx2 promotes myeloma progression in bone. Blood. 2015 Jun 04; 125(23):3598-608.
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Jackson GH, Morgan GJ, Davies FE, Wu P, Gregory WM, Bell SE, Szubert AJ, Navarro Coy N, Drayson MT, Owen RG, Feyler S, Ashcroft AJ, Ross FM, Byrne J, Roddie H, Rudin C, Boyd KD, Osborne WL, Cook G, Child JA. Osteonecrosis of the jaw and renal safety in patients with newly diagnosed multiple myeloma: Medical Research Council Myeloma IX Study results. Br J Haematol. 2014 Jul; 166(1):109-17.
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Graham TJ, Box G, Tunariu N, Crespo M, Spinks TJ, Miranda S, Attard G, de Bono J, Eccles SA, Davies FE, Robinson SP. Preclinical evaluation of imaging biomarkers for prostate cancer bone metastasis and response to cabozantinib. J Natl Cancer Inst. 2014 Apr; 106(4):dju033.
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Kamalakar A, Bendre MS, Washam CL, Fowler TW, Carver A, Dilley JD, Bracey JW, Akel NS, Margulies AG, Skinner RA, Swain FL, Hogue WR, Montgomery CO, Lahiji P, Maher JJ, Leitzel KE, Ali SM, Lipton A, Nicholas RW, Gaddy D, Suva LJ. Circulating interleukin-8 levels explain breast cancer osteolysis in mice and humans. Bone. 2014 Apr; 61:176-85.
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Bakhous A, Zhu H, Waheed S. Waldeström macroglobulinaemia relapsing with focal bone disease and achieving major response with single-agent zoledronic acid. Br J Haematol. 2013 Nov; 163(3):293.
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