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Phenytoin

"Phenytoin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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An anticonvulsant that is used in a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs.


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This graph shows the total number of publications written about "Phenytoin" by people in UAMS Profiles by year, and whether "Phenytoin" was a major or minor topic of these publications.
Bar chart showing 16 publications over 11 distinct years, with a maximum of 3 publications in 1998 and 2007
To see the data from this visualization as text, click here.