Item Type | Name |
Academic Article
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Identification of defects in glycosylphosphatidylinositol anchor biosynthesis in the Thy-1 expression mutants.
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Academic Article
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Differential expression of glycosylphosphatidylinositol-anchored proteins in a murine T cell hybridoma mutant producing limiting amounts of the glycolipid core. Implications for paroxysmal nocturnal hemoglobinuria.
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Academic Article
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Identification of a missing link in glycosylphosphatidylinositol anchor biosynthesis in mammalian cells.
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Academic Article
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Complexity of ethanolamine phosphate addition in the biosynthesis of glycosylphosphatidylinositol anchors in mammalian cells.
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Academic Article
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Inhibition of glycosylphosphatidylinositol anchor formation by mannosamine.
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Concept
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Antigen-Presenting Cells
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Concept
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Cell Cycle
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Concept
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Cell Membrane Permeability
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Concept
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Cell Movement
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Concept
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Cell Line, Transformed
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Concept
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Cell Membrane
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Concept
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Cell-Free System
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Concept
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Cell Division
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Concept
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Clone Cells
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Concept
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Eukaryotic Cells
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Concept
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Cell Compartmentation
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Concept
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Blood Cell Count
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Concept
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Cell Adhesion
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Concept
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Cell Transformation, Neoplastic
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Concept
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Cells, Cultured
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Concept
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Cell Differentiation
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Concept
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Carcinoma, Renal Cell
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Concept
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Bone Marrow Cells
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Concept
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Cell Nucleus
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Concept
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HeLa Cells
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Concept
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Hematopoietic Stem Cells
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Concept
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Hematopoietic Stem Cell Transplantation
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Concept
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Cell Hypoxia
|
Concept
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Vascular Cell Adhesion Molecule-1
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Concept
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Cell Line
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Concept
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Cell Survival
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Concept
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Proliferating Cell Nuclear Antigen
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Concept
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Cell Adhesion Molecules
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Concept
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Erythroid Precursor Cells
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Concept
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Cell Proliferation
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Concept
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Cell Lineage
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Concept
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Cell Nucleus Structures
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Concept
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Stem Cell Transplantation
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Concept
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Cell Death
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Concept
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Cell Surface Extensions
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Concept
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Mesenchymal Stem Cell Transplantation
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Concept
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Adult Stem Cells
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Concept
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HEK293 Cells
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Concept
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Endothelial Cells
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Concept
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Cell Line, Tumor
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Concept
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Cell Fusion
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Concept
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Cell Polarity
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Concept
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Killer Cells, Natural
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Concept
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Human Umbilical Vein Endothelial Cells
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Concept
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Stem Cells
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Concept
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Hybrid Cells
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Concept
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Tumor Cells, Cultured
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Concept
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Receptors, Antigen, T-Cell
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Concept
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Cell Transdifferentiation
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Concept
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Cell Cycle Proteins
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Concept
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Myeloid Cells
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Concept
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CHO Cells
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Concept
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Cell Culture Techniques
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Concept
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Stem Cell Niche
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Concept
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COS Cells
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Concept
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Active Transport, Cell Nucleus
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Concept
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NIH 3T3 Cells
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Concept
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Cell Growth Processes
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Grant
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PATHOBIOCHEMISTRY OF ACUTE PROMYELOCYTIC LEUKEMIA
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Grant
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PATHOBIOLOGY OF PAROXYSMAL NOCTURNAL HEMOGLOBINURIA
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Grant
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STUDIES OF THE SENTRIN FAMILY OF UBIQUITIN-LIKE PROTEINS
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Academic Article
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PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1.
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Academic Article
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Identification of a novel isopeptidase with dual specificity for ubiquitin- and NEDD8-conjugated proteins.
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Academic Article
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Biosynthesis and processing of the glycosylphosphatidylinositol anchor in mammalian cells.
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Academic Article
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A dominant-negative UBC12 mutant sequesters NEDD8 and inhibits NEDD8 conjugation in vivo.
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Academic Article
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Correction of the class H defect in glycosylphosphatidylinositol anchor biosynthesis in Ltk- cells by a human cDNA clone.
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Academic Article
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SUMO-specific protease 1 regulates mitochondrial biogenesis through PGC-1a.
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Academic Article
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Preferential modification of nuclear proteins by a novel ubiquitin-like molecule.
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Academic Article
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Characterization of NEDD8, a developmentally down-regulated ubiquitin-like protein.
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Academic Article
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Covalent modification of PML by the sentrin family of ubiquitin-like proteins.
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Academic Article
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Identification of three major sentrinization sites in PML.
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Academic Article
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Identification of NEDD8-conjugation site in human cullin-2.
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Academic Article
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The von Hippel-Lindau tumor suppressor gene product promotes, but is not essential for, NEDD8 conjugation to cullin-2.
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Academic Article
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SENP3-mediated de-conjugation of SUMO2/3 from promyelocytic leukemia is correlated with accelerated cell proliferation under mild oxidative stress.
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Academic Article
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Regulation of the NEDD8 conjugation system by a splicing variant, NUB1L.
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Academic Article
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NUB1, a NEDD8-interacting protein, is induced by interferon and down-regulates the NEDD8 expression.
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Academic Article
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Targeting of NEDD8 and its conjugates for proteasomal degradation by NUB1.
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Academic Article
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An essential role of small ubiquitin-like modifier (SUMO)-specific Protease 2 in myostatin expression and myogenesis.
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Academic Article
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NUB1-mediated targeting of the ubiquitin precursor UbC1 for its C-terminal hydrolysis.
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Academic Article
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Induction of SENP1 in endothelial cells contributes to hypoxia-driven VEGF expression and angiogenesis.
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Academic Article
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Differential regulation of c-Jun-dependent transcription by SUMO-specific proteases.
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Academic Article
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DeSUMOylation of MKK7 kinase by the SUMO2/3 protease SENP3 potentiates lipopolysaccharide-induced inflammatory signaling in macrophages.
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Academic Article
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De-SUMOylation of FOXC2 by SENP3 promotes the epithelial-mesenchymal transition in gastric cancer cells.
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Academic Article
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SENP1 induces prostatic intraepithelial neoplasia through multiple mechanisms.
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Academic Article
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SUMOylation and SENP3 regulate STAT3 activation in head and neck cancer.
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Academic Article
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Glycosyl-phosphatidylinositol anchor synthesis in paroxysmal nocturnal hemoglobinuria: partial or complete defect in an early step.
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Academic Article
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Protection against Fas/APO-1- and tumor necrosis factor-mediated cell death by a novel protein, sentrin.
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Academic Article
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Induction of the SUMO-specific protease 1 transcription by the androgen receptor in prostate cancer cells.
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Academic Article
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Characterization of a family of nucleolar SUMO-specific proteases with preference for SUMO-2 or SUMO-3.
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Academic Article
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Activation-induced aggregation and processing of the human Fas antigen. Detection with cytoplasmic domain-specific antibodies.
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Academic Article
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Characterization of a second member of the sentrin family of ubiquitin-like proteins.
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Academic Article
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sNASP inhibits TLR signaling to regulate immune response in sepsis.
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Academic Article
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Correction: SHP-1 regulates hematopoietic stem cell quiescence by coordinating TGF-? signaling.
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Academic Article
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Desumoylase SENP6 maintains osteochondroprogenitor homeostasis by suppressing the p53 pathway.
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Academic Article
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SUMOylated ORC2 Recruits a Histone Demethylase to Regulate Centromeric Histone Modification and Genomic Stability.
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Academic Article
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SHP-1 regulates hematopoietic stem cell quiescence by coordinating TGF-? signaling.
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Academic Article
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SENP1 regulates PTEN stability to dictate prostate cancer development.
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Academic Article
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Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional ? cells.
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Academic Article
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A Critical SUMO1 Modification of LKB1 Regulates AMPK Activity during Energy Stress.
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Academic Article
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Disturbed flow-activated p90RSK kinase accelerates atherosclerosis by inhibiting SENP2 function.
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Academic Article
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Induction of SENP1 in myocardium contributes to abnormities of mitochondria and cardiomyopathy.
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Academic Article
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Hyper-SUMOylation of the Kv7 potassium channel diminishes the M-current leading to seizures and sudden death.
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Academic Article
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De-SUMOylation enzyme of sentrin/SUMO-specific protease 2 regulates disturbed flow-induced SUMOylation of ERK5 and p53 that leads to endothelial dysfunction and atherosclerosis.
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Academic Article
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Targeting constitutively activated ?1 integrins inhibits prostate cancer metastasis.
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Academic Article
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Differential expression of SUMO-specific protease 7 variants regulates epithelial-mesenchymal transition.
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Academic Article
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Heparin and bone marrow-derived cell therapy: friend or foe?
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Academic Article
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SUMO-specific protease 1 promotes prostate cancer progression and metastasis.
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Academic Article
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SUMO-specific protease 1 is critical for early lymphoid development through regulation of STAT5 activation.
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Academic Article
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Microphthalmia-associated transcription factor, melanoma, and renal carcinoma: the small ubiquitin-like modifier connection.
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Academic Article
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Molecular imaging of mesenchymal stem cell: mechanistic insight into cardiac repair after experimental myocardial infarction.
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Academic Article
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Balancing act during development: lessons from a SUMO-less SF-1.
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Academic Article
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NF-?B induction of the SUMO protease SENP2: A negative feedback loop to attenuate cell survival response to genotoxic stress.
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Academic Article
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Dual targeting of tumor angiogenesis and chemotherapy by endostatin-cytosine deaminase-uracil phosphoribosyltransferase.
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Academic Article
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Redox regulation of the stability of the SUMO protease SENP3 via interactions with CHIP and Hsp90.
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Academic Article
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Regulation of DNA repair through deSUMOylation and SUMOylation of replication protein A complex.
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Academic Article
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PIASy stimulates HIF1a SUMOylation and negatively regulates HIF1a activity in response to hypoxia.
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Academic Article
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Human CD34+ cells in experimental myocardial infarction: long-term survival, sustained functional improvement, and mechanism of action.
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Academic Article
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SUMO-specific protease 2 is essential for suppression of polycomb group protein-mediated gene silencing during embryonic development.
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Academic Article
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SENP3 is responsible for HIF-1 transactivation under mild oxidative stress via p300 de-SUMOylation.
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Academic Article
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Adult progenitor cells for cardiac repair: preclinical studies.
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Academic Article
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Cadherin-11 promotes the metastasis of prostate cancer cells to bone.
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Academic Article
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SUMO-specific protease 1 is essential for stabilization of HIF1alpha during hypoxia.
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Academic Article
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Fusion of human hematopoietic progenitor cells and murine cardiomyocytes is mediated by alpha 4 beta 1 integrin/vascular cell adhesion molecule-1 interaction.
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Academic Article
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Neddylation of a breast cancer-associated protein recruits a class III histone deacetylase that represses NFkappaB-dependent transcription.
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Academic Article
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Nucleocytoplasmic shuttling modulates activity and ubiquitination-dependent turnover of SUMO-specific protease 2.
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Academic Article
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A novel approach to studying transformation of human stem cells into cardiac cells in vivo.
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Academic Article
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The pleiotropic effects of statins.
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Academic Article
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Blood-derived progenitor cells after recanalization of chronic coronary artery occlusions in humans.
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Academic Article
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Inhibition of tumor-necrosis-factor-alpha induced endothelial cell activation by a new class of PPAR-gamma agonists. An in vitro study showing receptor-independent effects.
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Academic Article
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Kaposi's sarcoma-associated herpesvirus K-bZIP represses gene transcription via SUMO modification.
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Academic Article
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A proline-90 residue unique to SUMO-4 prevents maturation and sumoylation.
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Academic Article
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Structural characterization of the TAP molecule: a phosphatidylinositol-linked glycoprotein distinct from the T cell receptor/T3 complex and Thy-1.
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Academic Article
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TAP transcription and phosphatidylinositol linkage mutants are defective in activation through the T cell receptor.
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Academic Article
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Gene encoding T-cell-activating protein TAP maps to the Ly-6 locus.
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Academic Article
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Expression of T-cell-activating protein in peripheral lymphocyte subsets.
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Academic Article
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Stimulation of T cells via the TAP molecule, a member in a family of activating proteins encoded in the Ly-6 locus.
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Academic Article
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Heat shock and Cd2+ exposure regulate PML and Daxx release from ND10 by independent mechanisms that modify the induction of heat-shock proteins 70 and 25 differently.
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Academic Article
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Bone marrow mononuclear cell therapy for acute myocardial infarction: a perspective from the cardiovascular cell therapy research network.
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Academic Article
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Analysis of thymocyte MHC specificity with thymocyte hybridomas.
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Academic Article
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Inflammatory cytokines stimulated C-reactive protein production by human coronary artery smooth muscle cells.
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Academic Article
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Spindle dynamics and cell cycle regulation of dynein in the budding yeast, Saccharomyces cerevisiae.
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Academic Article
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Transdifferentiation of human peripheral blood CD34+-enriched cell population into cardiomyocytes, endothelial cells, and smooth muscle cells in vivo.
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Academic Article
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A putative cation channel, NCA-1, and a novel protein, UNC-80, transmit neuronal activity in C. elegans.
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Academic Article
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SENP1 enhances androgen receptor-dependent transcription through desumoylation of histone deacetylase 1.
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Academic Article
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A tissue plasminogen activator/P-selectin fusion protein is an effective thrombolytic agent.
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Academic Article
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A cyclic hexapeptide is a potent antagonist of alpha 4 integrins.
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Academic Article
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Activation of CPP32-like protease in tumor necrosis factor-induced apoptosis is dependent on mitochondrial function.
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Academic Article
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Resistin promotes smooth muscle cell proliferation through activation of extracellular signal-regulated kinase 1/2 and phosphatidylinositol 3-kinase pathways.
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Academic Article
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Biosynthesis of phosphatidylinositol-glycan (PI-G)-anchored membrane proteins in cell-free systems: PI-G is an obligatory cosubstrate for COOH-terminal processing of nascent proteins.
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Academic Article
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Inhibition of alpha4 integrin and ICAM-1 markedly attenuate macrophage homing to atherosclerotic plaques in ApoE-deficient mice.
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Academic Article
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Both cell fusion and transdifferentiation account for the transformation of human peripheral blood CD34-positive cells into cardiomyocytes in vivo.
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Academic Article
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Tightly centromere-linked gene (SPO15) essential for meiosis in the yeast Saccharomyces cerevisiae.
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Academic Article
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Life and death of the cell.
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Academic Article
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Inhibition of mitochondrial respiratory chain complex I by TNF results in cytochrome c release, membrane permeability transition, and apoptosis.
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Academic Article
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Regulation of reactive oxygen species-induced apoptosis and necrosis by caspase 3-like proteases.
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Academic Article
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Fusion of the SUMO/Sentrin-specific protease 1 gene SENP1 and the embryonic polarity-related mesoderm development gene MESDC2 in a patient with an infantile teratoma and a constitutional t(12;15)(q13;q25).
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Academic Article
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Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-gamma activators.
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Academic Article
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Differential regulation of sentrinized proteins by a novel sentrin-specific protease.
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Academic Article
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Regulation of microphthalmia-associated transcription factor MITF protein levels by association with the ubiquitin-conjugating enzyme hUBC9.
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Academic Article
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Neuralized functions cell autonomously to regulate Drosophila sense organ development.
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Academic Article
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Regulation of apoptosis and cell cycle progression by MCL1. Differential role of proliferating cell nuclear antigen.
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Academic Article
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Direct proinflammatory effect of C-reactive protein on human endothelial cells.
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Academic Article
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Dynamic positioning of mitotic spindles in yeast: role of microtubule motors and cortical determinants.
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Academic Article
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Inhibition of coronary thrombosis and local inflammation by a noncarbohydrate selectin inhibitor.
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Academic Article
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Modulation of C-reactive protein-mediated monocyte chemoattractant protein-1 induction in human endothelial cells by anti-atherosclerosis drugs.
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Academic Article
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p47phox is required for atherosclerotic lesion progression in ApoE(-/-) mice.
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Academic Article
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Selection of T cell receptor expression mutants through the functionally linked Ly-6A.
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Academic Article
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A comparative study on the xenotransplantability of human solid tumors into mice with different genetic immune deficiencies.
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Academic Article
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TAP, a novel T cell-activating protein involved in the stimulation of MHC-restricted T lymphocytes.
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Academic Article
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The expression, function, and ontogeny of a novel T cell-activating protein, TAP, in the thymus.
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Academic Article
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SENP2-PLC?4 signaling regulates neurogenesis through the maintenance of calcium homeostasis.
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Academic Article
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Regulation of TLR4 signaling through the TRAF6/sNASP axis by reversible phosphorylation mediated by CK2 and PP4.
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Academic Article
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Dipeptidylpeptidase 4 promotes survival and stemness of acute myeloid leukemia stem cells.
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Academic Article
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Loss of SUMO-specific protease 2 causes isolated glucocorticoid deficiency by blocking adrenal cortex zonal transdifferentiation in mice.
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Grant
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Doxorubicin-induced Cardiotoxicity: the Role of Topoisomerase 2b
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