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@uark.edu
University of Arkansas for Medical Sciences
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PIASy stimulates HIF1a SUMOylation and negatively regulates HIF1a activity in response to hypoxia.
Kang X, Li J, Zou Y, Yi J, Zhang H, Cao M, Yeh ET, Cheng J. PIASy stimulates HIF1a SUMOylation and negatively regulates HIF1a activity in response to hypoxia. Oncogene. 2010 Oct 14; 29(41):5568-78.
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PubMed
subject areas
Animals
Cell Hypoxia
Cell Line
Cells, Cultured
Colonic Neoplasms
Cysteine Endopeptidases
Endopeptidases
Humans
Hypoxia-Inducible Factor 1, alpha Subunit
Immunoblotting
Immunohistochemistry
Immunoprecipitation
Mice
Mice, Knockout
Neovascularization, Pathologic
Protein Binding
Protein Inhibitors of Activated STAT
Reverse Transcriptase Polymerase Chain Reaction
RNA Interference
SUMO-1 Protein
Ubiquitin-Protein Ligases
authors with profiles
Edward Yeh