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Search Results to Michael Birrer

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One or more keywords matched the following items that are connected to Birrer, Michael

Item TypeName
Academic Article Choice of normal ovarian control influences determination of differentially expressed genes in ovarian cancer expression profiling studies.
Academic Article Gene expression profiles of serous, endometrioid, and clear cell subtypes of ovarian and endometrial cancer.
Academic Article Gene expression profiles associated with response to chemotherapy in epithelial ovarian cancers.
Academic Article Regulation of tumor angiogenesis by EZH2.
Academic Article Identification of novel therapeutic targets in microdissected clear cell ovarian cancers.
Concept Alleles
Concept Amino Acid Sequence
Concept Genes
Concept Multigene Family
Concept Base Sequence
Concept Molecular Structure
Concept Genes, p53
Concept Genes, fos
Concept Molecular Sequence Data
Concept Genes, myc
Concept Genes, Tumor Suppressor
Concept Gene Expression
Concept Consensus Sequence
Concept Genes, cdc
Concept Transgenes
Concept Genes, Reporter
Concept Genes, Suppressor
Concept Gene Expression Regulation, Enzymologic
Concept Sequence Homology
Concept Gene Amplification
Concept Gene Library
Concept Genes, jun
Concept Proto-Oncogenes
Concept Sequence Homology, Nucleic Acid
Concept Transcriptome
Concept Gene Regulatory Networks
Concept Gene-Environment Interaction
Concept Gene Expression Regulation, Developmental
Concept Gene Expression Regulation
Concept Gene Silencing
Concept Oncogenes
Concept Genes, Dominant
Concept Genes, Viral
Concept Genome, Human
Concept Genes, ras
Concept Gene Dosage
Concept Genes, erbB-2
Concept Gene Deletion
Concept Repetitive Sequences, Nucleic Acid
Concept Genes, erbB-1
Concept Genes, BRCA1
Concept Gene Expression Profiling
Concept Gene Knockdown Techniques
Concept Genome
Concept Genes, BRCA2
Concept Genes, Neoplasm
Concept Polymorphism, Single Nucleotide
Concept Quantitative Trait Loci
Concept Gene Expression Regulation, Neoplastic
Concept Conserved Sequence
Concept Genetic Loci
Academic Article CXCL12/CXCR4 blockade induces multimodal antitumor effects that prolong survival in an immunocompetent mouse model of ovarian cancer.
Academic Article Cyclin A is a c-Jun target gene and is necessary for c-Jun-induced anchorage-independent growth in RAT1a cells.
Academic Article Tissue-based immune monitoring I: tumor core needle biopsies allow in-depth interrogation of the tumor microenvironment.
Academic Article Tissue-based immune monitoring II: multiple tumor sites reveal immunologic homogeneity in serous ovarian carcinoma.
Academic Article p75-Ras-GRF1 is a c-Jun/AP-1 target protein: its up regulation results in increased Ras activity and is necessary for c-Jun-induced nonadherent growth of Rat1a cells.
Academic Article Wnt5a suppresses epithelial ovarian cancer by promoting cellular senescence.
Academic Article Targeting the Nuclear Import Receptor Kpn?1 as an Anticancer Therapeutic.
Academic Article Genomic analysis of epithelial ovarian cancer.
Academic Article Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer.
Academic Article Dysregulation of miR-181c expression influences recurrence of endometrial endometrioid adenocarcinoma by modulating NOTCH2 expression: An NRG Oncology/Gynecologic Oncology Group study.
Academic Article A gene signature predicting for survival in suboptimally debulked patients with ovarian cancer.
Academic Article Inhibition of Hedgehog signaling antagonizes serous ovarian cancer growth in a primary xenograft model.
Academic Article ALDH1A1 is a novel EZH2 target gene in epithelial ovarian cancer identified by genome-wide approaches.
Academic Article Expression profiling of serous low malignant potential, low-grade, and high-grade tumors of the ovary.
Academic Article Mutations in Homologous Recombination Genes and Outcomes in Ovarian Carcinoma Patients in GOG 218: An NRG Oncology/Gynecologic Oncology Group Study.
Academic Article Asparagine synthetase is a predictive biomarker of L-asparaginase activity in ovarian cancer cell lines.
Academic Article Egr1 regulates the coordinated expression of numerous EGF receptor target genes as identified by ChIP-on-chip.
Academic Article Multi-gene expression predictors of single drug responses to adjuvant chemotherapy in ovarian carcinoma: predicting platinum resistance.
Academic Article Better therapeutic trials in ovarian cancer.
Academic Article Expression profiling of mucinous tumors of the ovary identifies genes of clinicopathologic importance.
Academic Article Genome wide DNA copy number analysis of serous type ovarian carcinomas identifies genetic markers predictive of clinical outcome.
Academic Article Dysregulated microRNAs and their predicted targets associated with endometrioid endometrial adenocarcinoma in Hong Kong women.
Academic Article Inhibition of AP-1 transcriptional activity blocks the migration, invasion, and experimental metastasis of murine osteosarcoma.
Academic Article Dicer, Drosha, and outcomes in patients with ovarian cancer.
Academic Article Associations between ERBB2 amplification and progression-free survival and overall survival in advanced stage, suboptimally-resected epithelial ovarian cancers: a Gynecologic Oncology Group Study.
Academic Article BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group.
Academic Article A key role for early growth response-1 and nuclear factor-kappaB in mediating and maintaining GRO/CXCR2 proliferative signaling in esophageal cancer.
Academic Article NORE1A tumor suppressor candidate modulates p21CIP1 via p53.
Academic Article Biomarker discovery in epithelial ovarian cancer by genomic approaches.
Academic Article Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth.
Academic Article An RNA interference lethality screen of the human druggable genome to identify molecular vulnerabilities in epithelial ovarian cancer.
Academic Article Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential.
Academic Article Gene alterations identified by expression profiling in tumor-associated endothelial cells from invasive ovarian carcinoma.
Academic Article Consensus on Molecular Subtypes of High-Grade Serous Ovarian Carcinoma.
Academic Article Ovarian cancer: markers of response.
Academic Article A gene signature predictive for outcome in advanced ovarian cancer identifies a survival factor: microfibril-associated glycoprotein 2.
Academic Article EGF-R regulates MMP function in fibroblasts through MAPK and AP-1 pathways.
Academic Article Low-grade and high-grade serous Mullerian carcinoma: review and analysis of publicly available gene expression profiles.
Academic Article Prognostically relevant gene signatures of high-grade serous ovarian carcinoma.
Academic Article Overexpression of elafin in ovarian carcinoma is driven by genomic gains and activation of the nuclear factor kappaB pathway and is associated with poor overall survival.
Academic Article Primordial germ cells as a potential shared cell of origin for mucinous cystic neoplasms of the pancreas and mucinous ovarian tumors.
Academic Article Inherited variants in regulatory T cell genes and outcome of ovarian cancer.
Academic Article Whole genome oligonucleotide-based array comparative genomic hybridization analysis identified fibroblast growth factor 1 as a prognostic marker for advanced-stage serous ovarian adenocarcinomas.
Academic Article Identification of cJun-responsive genes in Rat-1a cells using multiple techniques: increased expression of stathmin is necessary for cJun-mediated anchorage-independent growth.
Academic Article GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.
Academic Article curatedOvarianData: clinically annotated data for the ovarian cancer transcriptome.
Academic Article Activation of NF-kappaB signaling by inhibitor of NF-kappaB kinase beta increases aggressiveness of ovarian cancer.
Academic Article Nuclear factor kappaB transcription factors are coexpressed and convey a poor outcome in ovarian cancer.
Academic Article AP-1 complexes containing cJun and JunB cause cellular transformation of Rat1a fibroblasts and share transcriptional targets.
Academic Article A link between histone deacetylase inhibitors and NF- kappaB signaling.
Academic Article Up-regulation of stromal versican expression in advanced stage serous ovarian cancer.
Academic Article The aryl hydrocarbon receptor repressor is a putative tumor suppressor gene in multiple human cancers.
Academic Article Comparing Platforms for Messenger RNA Expression Profiling of Archival Formalin-Fixed, Paraffin-Embedded Tissues.
Academic Article Creation of a Human Secretome: A Novel Composite Library of Human Secreted Proteins: Validation Using Ovarian Cancer Gene Expression Data and a Virtual Secretome Array.
Academic Article FGF18 as a prognostic and therapeutic biomarker in ovarian cancer.
Academic Article Loss of LKB1 and PTEN tumor suppressor genes in the ovarian surface epithelium induces papillary serous ovarian cancer.
Academic Article DNA copy number abnormality of oral squamous cell carcinoma detected with cDNA array-based comparative genomic hybridization.
Academic Article Classification of ovarian cancer: a genomic analysis.
Academic Article IL6-STAT3-HIF signaling and therapeutic response to the angiogenesis inhibitor sunitinib in ovarian clear cell cancer.
Academic Article Jun blockade of erythropoiesis: role for repression of GATA-1 by HERP2.
Academic Article The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing.
Academic Article Activation of YAP1 is associated with poor prognosis and response to taxanes in ovarian cancer.
Academic Article Cancer-associated fibroblasts regulate endothelial adhesion protein LPP to promote ovarian cancer chemoresistance.
Academic Article A polymorphism in the GALNT2 gene and ovarian cancer risk in four population based case-control studies.
Academic Article Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers.
Academic Article Mutation of ERBB2 provides a novel alternative mechanism for the ubiquitous activation of RAS-MAPK in ovarian serous low malignant potential tumors.
Academic Article Cyclin E amplification and overexpression in clear cell adenocarcinoma of the ovary.
Academic Article Connective tissue growth factor as a novel therapeutic target in high grade serous ovarian cancer.
Academic Article The Karyopherin proteins, Crm1 and Karyopherin beta1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation.
Academic Article Comparative meta-analysis of prognostic gene signatures for late-stage ovarian cancer.
Academic Article Anticancer Immunotherapy by MFAP5 Blockade Inhibits Fibrosis and Enhances Chemosensitivity in Ovarian and Pancreatic Cancer.
Academic Article RRP22 is a farnesylated, nucleolar, Ras-related protein with tumor suppressor potential.
Academic Article Integrative Kinome Profiling Identifies mTORC1/2 Inhibition as Treatment Strategy in Ovarian Clear Cell Carcinoma.
Academic Article Inflammatory cytokine tumor necrosis factor alpha confers precancerous phenotype in an organoid model of normal human ovarian surface epithelial cells.
Academic Article Prognostic relevance of c-MYC gene amplification and polysomy for chromosome 8 in suboptimally-resected, advanced stage epithelial ovarian cancers: a Gynecologic Oncology Group study.
Academic Article Identification of overexpression and amplification of ABCF2 in clear cell ovarian adenocarcinomas by cDNA microarray analyses.
Academic Article The Impact of Stroma Admixture on Molecular Subtypes and Prognostic Gene Signatures in Serous Ovarian Cancer.
Academic Article Identification of a potential ovarian cancer stem cell gene expression profile from advanced stage papillary serous ovarian cancer.
Academic Article Thymosin beta4 is a determinant of the transformed phenotype and invasiveness of S-adenosylmethionine decarboxylase-transfected fibroblasts.
Academic Article CD44 Splice Variant v8-10 as a Marker of Serous Ovarian Cancer Prognosis.
Academic Article The Doppelg?nger Effect: Hidden Duplicates in Databases of Transcriptome Profiles.
Academic Article Cyclin E expression is a significant predictor of survival in advanced, suboptimally debulked ovarian epithelial cancers: a Gynecologic Oncology Group study.
Academic Article The regulation of tumor suppressor genes by oncogenes.
Academic Article Expression profiling identifies altered expression of genes that contribute to the inhibition of transforming growth factor-beta signaling in ovarian cancer.
Academic Article CD157 in ovarian carcinoma: how does it help us?
Academic Article SUZ12 promotes human epithelial ovarian cancer by suppressing apoptosis via silencing HRK.
Academic Article Biologic directed therapies in gynecologic oncology.
Academic Article MAPK pathways mediate hyperoxia-induced oncotic cell death in lung epithelial cells.
Academic Article Common variants at 19p13 are associated with susceptibility to ovarian cancer.
Academic Article The origin of ovarian cancer?is it getting clearer?
Academic Article ATR inhibition disrupts rewired homologous recombination and fork protection pathways in PARP inhibitor-resistant BRCA-deficient cancer cells.
Academic Article Identification of FGFR4 as a potential therapeutic target for advanced-stage, high-grade serous ovarian cancer.
Academic Article AAV9 delivering a modified human Mullerian inhibiting substance as a gene therapy in patient-derived xenografts of ovarian cancer.
Academic Article HMG-I/Y is a c-Jun/activator protein-1 target gene and is necessary for c-Jun-induced anchorage-independent growth in Rat1a cells.
Academic Article Whole genome expression profiling of advance stage papillary serous ovarian cancer reveals activated pathways.
Academic Article Comparison of expression profiles in ovarian epithelium in vivo and ovarian cancer identifies novel candidate genes involved in disease pathogenesis.
Academic Article The anterior gradient homolog 3 (AGR3) gene is associated with differentiation and survival in ovarian cancer.
Academic Article Integrated analysis of multiple microarray datasets identifies a reproducible survival predictor in ovarian cancer.
Academic Article A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer.
Academic Article Identification of DNA copy number changes in microdissected serous ovarian cancer tissue using a cDNA microarray platform.
Academic Article Activator protein-1 contributes to high NaCl-induced increase in tonicity-responsive enhancer/osmotic response element-binding protein transactivating activity.
Academic Article Biomarkers of mucinous tumors of the ovary.
Academic Article Cell cycle and related protein.
Academic Article p21-activated kinase 3 (PAK3) is an AP-1 regulated gene contributing to actin organisation and migration of transformed fibroblasts.
Academic Article Multiomic Analysis of Subtype Evolution and Heterogeneity in High-Grade Serous Ovarian Carcinoma.
Grant The Use of Transcriptional Factors as Targets and Agents in Carcinogenesis
Grant The FGF18/FGFR4 amplicon: Novel therapeutic biomarkers for ovarian cancer
Grant The Molecular Genetics of Gynecologic Cancers
Grant Validation of a genomic signature that predicts for sub-optimal debulking of epithelial ovarian cancer
Grant Novel Biomarkers in Ovarian Cancer
Grant Genomic Stratification of Ovarian Cancer Patients
Academic Article Activation domains of L-Myc and c-Myc determine their transforming potencies in rat embryo cells.
Academic Article Regions within the c-Myc protein that are necessary for transformation are also required for inhibition of differentiation of murine erythroleukemia cells.
Academic Article Structure and expression of the human L-myc gene reveal a complex pattern of alternative mRNA processing.
Academic Article Multiple mechanisms for transcriptional regulation of the myc gene family in small-cell lung cancer.
Academic Article Molecular genetics of lung cancer.
Academic Article Chromosomal deletion, gene amplification, alternative processing, and autocrine growth factor production in the pathogenesis of human lung cancer.
Academic Article Translational research and epithelial carcinogenesis: molecular diagnostic assays now--molecular screening assays soon?
Academic Article Occurrence of p53 gene abnormalities in gastric carcinoma tumors and cell lines.
Academic Article Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73.
Academic Article The role of jun and fos gene family members in 12-O-tetradecanoylphorbol-13-acetate induced hemopoietic differentiation.
Academic Article Expression of the atrial natriuretic factor gene in small cell lung cancer tumors and tumor cell lines.
Academic Article Transcription factors and recessive oncogenes in the pathogenesis of human lung cancer.
Academic Article p53: a frequent target for genetic abnormalities in lung cancer.
Academic Article Deregulated expression of human c-jun transforms primary rat embryo cells in cooperation with an activated c-Ha-ras gene and transforms rat-1a cells as a single gene.
Academic Article Genetic changes in the pathogenesis of lung cancer.
Academic Article A transfected L-myc gene can substitute for c-myc in blocking murine erythroleukemia differentiation.
Academic Article The human L-myc gene encodes multiple nuclear phosphoproteins from alternatively processed mRNAs.
Academic Article Transformation by Raf and other oncogenes renders cells differentially sensitive to growth inhibition by a dominant negative c-jun mutant.
Academic Article Constitutive cJun expression induces partial macrophage differentiation in U-937 cells.
Academic Article Dominant negative mutant of c-Jun inhibits NF-AT transcriptional activity and prevents IL-2 gene transcription.
Academic Article Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells.
Academic Article The molecular biology of lung cancer: application to early detection and prevention.
Academic Article p53 and Ki-ras gene mutations in epithelial ovarian neoplasms.
Academic Article Initiators and promoters of lung cancer.
Academic Article Suppression of oncogene-induced transformation by a deletion mutant of c-jun.
Academic Article Role of c-jun in human myeloid leukemia cell apoptosis induced by pharmacological inhibitors of protein kinase C.
Academic Article Effect of 1-beta-D-arabinofuranosylcytosine on apoptosis and differentiation in human monocytic leukemia cells (U937) expressing a c-Jun dominant-negative mutant protein (TAM67).
Academic Article Breast cancer growth is inhibited by vasoactive intestinal peptide (VIP) hybrid, a synthetic VIP receptor antagonist.
Academic Article PACAP stimulates c-fos mRNAs in small cell lung cancer cells.
Academic Article Regulation of nuclear oncogenes expressed in lung cancer cell lines.
Academic Article Discoveries in the cell cycle and ovarian cancer.
Academic Article Molecular characterization of adenocarcinoma of the cervix.
Academic Article AP1 regulation of proliferation and initiation of apoptosis in erythropoietin-dependent erythroid cells.
Academic Article RRR-alpha-tocopheryl succinate induction of prolonged activation of c-jun amino-terminal kinase and c-jun during induction of apoptosis in human MDA-MB-435 breast cancer cells.
Academic Article cJun overexpression in MCF-7 breast cancer cells produces a tumorigenic, invasive and hormone resistant phenotype.
Academic Article Complementation analysis of measles virus mutants isolated from persistently infected lymphoblastoid cell lines.
Academic Article Abnormal expression of the retinoblastoma gene in ovarian neoplasms and correlation to p53 and K-ras mutations.
Academic Article c-jun and multistage carcinogenesis: association of overexpression of introduced c-jun with progression toward a neoplastic endpoint in mouse JB6 cells sensitive to tumor promoter-induced transformation.
Academic Article The molecular genetics of gyn malignancies.
Academic Article Bombesin stimulates c-fos and c-jun mRNAs in small cell lung cancer cells.
Academic Article Mechanism of action of a dominant-negative mutant of c-Jun.
Academic Article Stable expression of a c-JUN deletion mutant in two malignant mouse epidermal cell lines blocks tumor formation in nude mice.
Academic Article Altered cJUN expression: an early event in human lung carcinogenesis.
Academic Article Regulation of urokinase-type plasminogen activator expression by the v-mos oncogene.
Academic Article Activation and inhibition of the AP-1 complex in human breast cancer cells.
Academic Article The human papillomavirus type 16 E7 gene product interacts with and trans-activates the AP1 family of transcription factors.
Academic Article Dominant-negative mutants of cJun inhibit AP-1 activity through multiple mechanisms and with different potencies.
Academic Article Use of transcription factors as agents and targets for drug development.
Academic Article Analysis of Ki-ras, p53, and MDM2 genes in uterine leiomyomas and leiomyosarcomas.
Academic Article FHIT gene expression in human ovarian, endometrial, and cervical cancer cell lines.
Academic Article Breast cancer cells have lower activating protein 1 transcription factor activity than normal mammary epithelial cells.
Academic Article PACAP hybrid: a new PACAP receptor antagonist.
Academic Article Retinoic acid receptor beta expression and growth inhibition of gynecologic cancer cells by the synthetic retinoid N-(4-hydroxyphenyl) retinamide.
Academic Article PACAP(6-38) inhibits the growth of prostate cancer cells.
Academic Article Tumor necrosis factor alpha gene regulation: enhancement of C/EBPbeta-induced activation by c-Jun.
Academic Article Frequent loss of KAI1 expression in squamous and lymphoid neoplasms. An immunohistochemical study of archival tissues.
Academic Article Activator protein-1 mediates induced but not basal epidermal growth factor receptor gene expression.
Academic Article p27 and cyclin D1 abnormalities in uterine papillary serous carcinoma.
Academic Article Endocervical cancer is associated with an increase in the ligands and receptors for transforming growth factor-beta and a contrasting decrease in p27(Kip1).
Academic Article Lovastatin induces apoptosis in a primitive neuroectodermal tumor cell line in association with RB down-regulation and loss of the G1 checkpoint.
Academic Article c-Jun triggers apoptosis in human vascular endothelial cells.
Academic Article TNF-alpha gene expression in macrophages: regulation by NF-kappa B is independent of c-Jun or C/EBP beta.
Academic Article Ras uses the novel tumor suppressor RASSF1 as an effector to mediate apoptosis.
Academic Article Alterations in the gene expression profile of MCF-7 breast tumor cells in response to c-Jun.
Academic Article In situ detection of unexpected patterns of mutant p53 gene expression in non-small cell lung cancers.
Academic Article RASSF6 is a novel member of the RASSF family of tumor suppressors.
Academic Article Identification of molecular markers and signaling pathway in endometrial cancer in Hong Kong Chinese women by genome-wide gene expression profiling.
Academic Article FOXO3a loss is a frequent early event in high-grade pelvic serous carcinogenesis.
Academic Article Ovarian cancer: genomic analysis.
Academic Article Identification of LMX1B as a novel oncogene in human ovarian cancer.
Academic Article Epithelial ovarian cancer: the molecular genetics of epithelial ovarian cancer.
Academic Article How can molecular abnormalities influence our clinical approach.
Academic Article Inhibition of Kpn?1 mediated nuclear import enhances cisplatin chemosensitivity in cervical cancer.
Academic Article Sex Hormones, Insulin, and Insulin-like Growth Factors in Recurrence of High-Stage Endometrial Cancer.
Academic Article A highly annotated database of genes associated with platinum resistance in cancer.
Academic Article Impact of homologous recombination status and responses with veliparib combined with first-line chemotherapy in ovarian cancer in the Phase 3 VELIA/GOG-3005 study.
Academic Article Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer.

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