Item Type | Name |
Academic Article
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Choice of normal ovarian control influences determination of differentially expressed genes in ovarian cancer expression profiling studies.
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Academic Article
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Gene expression profiles of serous, endometrioid, and clear cell subtypes of ovarian and endometrial cancer.
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Academic Article
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Gene expression profiles associated with response to chemotherapy in epithelial ovarian cancers.
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Academic Article
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Regulation of tumor angiogenesis by EZH2.
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Academic Article
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Identification of novel therapeutic targets in microdissected clear cell ovarian cancers.
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Concept
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Alleles
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Concept
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Amino Acid Sequence
|
Concept
|
Genes
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Concept
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Multigene Family
|
Concept
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Base Sequence
|
Concept
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Molecular Structure
|
Concept
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Genes, p53
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Concept
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Genes, fos
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Concept
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Molecular Sequence Data
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Concept
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Genes, myc
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Concept
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Genes, Tumor Suppressor
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Concept
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Gene Expression
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Concept
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Consensus Sequence
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Concept
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Genes, cdc
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Concept
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Transgenes
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Concept
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Genes, Reporter
|
Concept
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Genes, Suppressor
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Concept
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Gene Expression Regulation, Enzymologic
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Concept
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Sequence Homology
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Concept
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Gene Amplification
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Concept
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Gene Library
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Concept
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Genes, jun
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Concept
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Proto-Oncogenes
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Concept
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Sequence Homology, Nucleic Acid
|
Concept
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Transcriptome
|
Concept
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Gene Regulatory Networks
|
Concept
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Gene-Environment Interaction
|
Concept
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Gene Expression Regulation, Developmental
|
Concept
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Gene Expression Regulation
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Concept
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Gene Silencing
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Concept
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Oncogenes
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Concept
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Genes, Dominant
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Concept
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Genes, Viral
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Concept
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Genome, Human
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Concept
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Genes, ras
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Concept
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Gene Dosage
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Concept
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Genes, erbB-2
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Concept
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Gene Deletion
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Concept
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Repetitive Sequences, Nucleic Acid
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Concept
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Genes, erbB-1
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Concept
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Genes, BRCA1
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Concept
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Gene Expression Profiling
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Concept
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Gene Knockdown Techniques
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Concept
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Genome
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Concept
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Genes, BRCA2
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Concept
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Genes, Neoplasm
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Concept
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Polymorphism, Single Nucleotide
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Concept
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Quantitative Trait Loci
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Concept
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Gene Expression Regulation, Neoplastic
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Concept
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Conserved Sequence
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Concept
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Genetic Loci
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Academic Article
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CXCL12/CXCR4 blockade induces multimodal antitumor effects that prolong survival in an immunocompetent mouse model of ovarian cancer.
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Academic Article
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Cyclin A is a c-Jun target gene and is necessary for c-Jun-induced anchorage-independent growth in RAT1a cells.
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Academic Article
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Tissue-based immune monitoring I: tumor core needle biopsies allow in-depth interrogation of the tumor microenvironment.
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Academic Article
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Tissue-based immune monitoring II: multiple tumor sites reveal immunologic homogeneity in serous ovarian carcinoma.
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Academic Article
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p75-Ras-GRF1 is a c-Jun/AP-1 target protein: its up regulation results in increased Ras activity and is necessary for c-Jun-induced nonadherent growth of Rat1a cells.
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Academic Article
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Wnt5a suppresses epithelial ovarian cancer by promoting cellular senescence.
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Academic Article
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Targeting the Nuclear Import Receptor Kpn?1 as an Anticancer Therapeutic.
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Academic Article
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Genomic analysis of epithelial ovarian cancer.
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Academic Article
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Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer.
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Academic Article
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Dysregulation of miR-181c expression influences recurrence of endometrial endometrioid adenocarcinoma by modulating NOTCH2 expression: An NRG Oncology/Gynecologic Oncology Group study.
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Academic Article
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A gene signature predicting for survival in suboptimally debulked patients with ovarian cancer.
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Academic Article
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Inhibition of Hedgehog signaling antagonizes serous ovarian cancer growth in a primary xenograft model.
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Academic Article
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ALDH1A1 is a novel EZH2 target gene in epithelial ovarian cancer identified by genome-wide approaches.
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Academic Article
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Expression profiling of serous low malignant potential, low-grade, and high-grade tumors of the ovary.
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Academic Article
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Mutations in Homologous Recombination Genes and Outcomes in Ovarian Carcinoma Patients in GOG 218: An NRG Oncology/Gynecologic Oncology Group Study.
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Academic Article
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Asparagine synthetase is a predictive biomarker of L-asparaginase activity in ovarian cancer cell lines.
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Academic Article
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Egr1 regulates the coordinated expression of numerous EGF receptor target genes as identified by ChIP-on-chip.
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Academic Article
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Multi-gene expression predictors of single drug responses to adjuvant chemotherapy in ovarian carcinoma: predicting platinum resistance.
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Academic Article
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Better therapeutic trials in ovarian cancer.
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Academic Article
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Expression profiling of mucinous tumors of the ovary identifies genes of clinicopathologic importance.
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Academic Article
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Genome wide DNA copy number analysis of serous type ovarian carcinomas identifies genetic markers predictive of clinical outcome.
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Academic Article
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Dysregulated microRNAs and their predicted targets associated with endometrioid endometrial adenocarcinoma in Hong Kong women.
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Academic Article
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Inhibition of AP-1 transcriptional activity blocks the migration, invasion, and experimental metastasis of murine osteosarcoma.
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Academic Article
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Dicer, Drosha, and outcomes in patients with ovarian cancer.
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Academic Article
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Associations between ERBB2 amplification and progression-free survival and overall survival in advanced stage, suboptimally-resected epithelial ovarian cancers: a Gynecologic Oncology Group Study.
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Academic Article
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BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group.
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Academic Article
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A key role for early growth response-1 and nuclear factor-kappaB in mediating and maintaining GRO/CXCR2 proliferative signaling in esophageal cancer.
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Academic Article
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NORE1A tumor suppressor candidate modulates p21CIP1 via p53.
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Academic Article
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Biomarker discovery in epithelial ovarian cancer by genomic approaches.
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Academic Article
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Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth.
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Academic Article
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An RNA interference lethality screen of the human druggable genome to identify molecular vulnerabilities in epithelial ovarian cancer.
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Academic Article
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Calcium-dependent FAK/CREB/TNNC1 signalling mediates the effect of stromal MFAP5 on ovarian cancer metastatic potential.
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Academic Article
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Gene alterations identified by expression profiling in tumor-associated endothelial cells from invasive ovarian carcinoma.
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Academic Article
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Consensus on Molecular Subtypes of High-Grade Serous Ovarian Carcinoma.
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Academic Article
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Ovarian cancer: markers of response.
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Academic Article
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A gene signature predictive for outcome in advanced ovarian cancer identifies a survival factor: microfibril-associated glycoprotein 2.
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Academic Article
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EGF-R regulates MMP function in fibroblasts through MAPK and AP-1 pathways.
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Academic Article
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Low-grade and high-grade serous Mullerian carcinoma: review and analysis of publicly available gene expression profiles.
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Academic Article
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Prognostically relevant gene signatures of high-grade serous ovarian carcinoma.
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Academic Article
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Overexpression of elafin in ovarian carcinoma is driven by genomic gains and activation of the nuclear factor kappaB pathway and is associated with poor overall survival.
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Academic Article
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Primordial germ cells as a potential shared cell of origin for mucinous cystic neoplasms of the pancreas and mucinous ovarian tumors.
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Academic Article
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Inherited variants in regulatory T cell genes and outcome of ovarian cancer.
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Academic Article
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Whole genome oligonucleotide-based array comparative genomic hybridization analysis identified fibroblast growth factor 1 as a prognostic marker for advanced-stage serous ovarian adenocarcinomas.
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Academic Article
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Identification of cJun-responsive genes in Rat-1a cells using multiple techniques: increased expression of stathmin is necessary for cJun-mediated anchorage-independent growth.
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Academic Article
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GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.
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Academic Article
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curatedOvarianData: clinically annotated data for the ovarian cancer transcriptome.
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Academic Article
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Activation of NF-kappaB signaling by inhibitor of NF-kappaB kinase beta increases aggressiveness of ovarian cancer.
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Academic Article
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Nuclear factor kappaB transcription factors are coexpressed and convey a poor outcome in ovarian cancer.
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Academic Article
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AP-1 complexes containing cJun and JunB cause cellular transformation of Rat1a fibroblasts and share transcriptional targets.
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Academic Article
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A link between histone deacetylase inhibitors and NF- kappaB signaling.
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Academic Article
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Up-regulation of stromal versican expression in advanced stage serous ovarian cancer.
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Academic Article
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The aryl hydrocarbon receptor repressor is a putative tumor suppressor gene in multiple human cancers.
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Academic Article
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Comparing Platforms for Messenger RNA Expression Profiling of Archival Formalin-Fixed, Paraffin-Embedded Tissues.
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Academic Article
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Creation of a Human Secretome: A Novel Composite Library of Human Secreted Proteins: Validation Using Ovarian Cancer Gene Expression Data and a Virtual Secretome Array.
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Academic Article
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FGF18 as a prognostic and therapeutic biomarker in ovarian cancer.
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Academic Article
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Loss of LKB1 and PTEN tumor suppressor genes in the ovarian surface epithelium induces papillary serous ovarian cancer.
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Academic Article
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DNA copy number abnormality of oral squamous cell carcinoma detected with cDNA array-based comparative genomic hybridization.
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Academic Article
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Classification of ovarian cancer: a genomic analysis.
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Academic Article
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IL6-STAT3-HIF signaling and therapeutic response to the angiogenesis inhibitor sunitinib in ovarian clear cell cancer.
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Academic Article
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Jun blockade of erythropoiesis: role for repression of GATA-1 by HERP2.
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Academic Article
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The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing.
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Academic Article
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Activation of YAP1 is associated with poor prognosis and response to taxanes in ovarian cancer.
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Academic Article
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Cancer-associated fibroblasts regulate endothelial adhesion protein LPP to promote ovarian cancer chemoresistance.
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Academic Article
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A polymorphism in the GALNT2 gene and ovarian cancer risk in four population based case-control studies.
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Academic Article
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Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers.
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Academic Article
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Mutation of ERBB2 provides a novel alternative mechanism for the ubiquitous activation of RAS-MAPK in ovarian serous low malignant potential tumors.
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Academic Article
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Cyclin E amplification and overexpression in clear cell adenocarcinoma of the ovary.
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Academic Article
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Connective tissue growth factor as a novel therapeutic target in high grade serous ovarian cancer.
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Academic Article
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The Karyopherin proteins, Crm1 and Karyopherin beta1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation.
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Academic Article
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Comparative meta-analysis of prognostic gene signatures for late-stage ovarian cancer.
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Academic Article
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Anticancer Immunotherapy by MFAP5 Blockade Inhibits Fibrosis and Enhances Chemosensitivity in Ovarian and Pancreatic Cancer.
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Academic Article
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RRP22 is a farnesylated, nucleolar, Ras-related protein with tumor suppressor potential.
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Academic Article
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Integrative Kinome Profiling Identifies mTORC1/2 Inhibition as Treatment Strategy in Ovarian Clear Cell Carcinoma.
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Academic Article
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Inflammatory cytokine tumor necrosis factor alpha confers precancerous phenotype in an organoid model of normal human ovarian surface epithelial cells.
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Academic Article
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Prognostic relevance of c-MYC gene amplification and polysomy for chromosome 8 in suboptimally-resected, advanced stage epithelial ovarian cancers: a Gynecologic Oncology Group study.
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Academic Article
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Identification of overexpression and amplification of ABCF2 in clear cell ovarian adenocarcinomas by cDNA microarray analyses.
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Academic Article
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The Impact of Stroma Admixture on Molecular Subtypes and Prognostic Gene Signatures in Serous Ovarian Cancer.
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Academic Article
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Identification of a potential ovarian cancer stem cell gene expression profile from advanced stage papillary serous ovarian cancer.
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Academic Article
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Thymosin beta4 is a determinant of the transformed phenotype and invasiveness of S-adenosylmethionine decarboxylase-transfected fibroblasts.
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Academic Article
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CD44 Splice Variant v8-10 as a Marker of Serous Ovarian Cancer Prognosis.
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Academic Article
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The Doppelg?nger Effect: Hidden Duplicates in Databases of Transcriptome Profiles.
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Academic Article
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Cyclin E expression is a significant predictor of survival in advanced, suboptimally debulked ovarian epithelial cancers: a Gynecologic Oncology Group study.
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Academic Article
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The regulation of tumor suppressor genes by oncogenes.
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Academic Article
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Expression profiling identifies altered expression of genes that contribute to the inhibition of transforming growth factor-beta signaling in ovarian cancer.
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Academic Article
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CD157 in ovarian carcinoma: how does it help us?
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Academic Article
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SUZ12 promotes human epithelial ovarian cancer by suppressing apoptosis via silencing HRK.
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Academic Article
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Biologic directed therapies in gynecologic oncology.
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Academic Article
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MAPK pathways mediate hyperoxia-induced oncotic cell death in lung epithelial cells.
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Academic Article
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Common variants at 19p13 are associated with susceptibility to ovarian cancer.
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Academic Article
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The origin of ovarian cancer?is it getting clearer?
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Academic Article
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ATR inhibition disrupts rewired homologous recombination and fork protection pathways in PARP inhibitor-resistant BRCA-deficient cancer cells.
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Academic Article
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Identification of FGFR4 as a potential therapeutic target for advanced-stage, high-grade serous ovarian cancer.
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Academic Article
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AAV9 delivering a modified human Mullerian inhibiting substance as a gene therapy in patient-derived xenografts of ovarian cancer.
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Academic Article
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HMG-I/Y is a c-Jun/activator protein-1 target gene and is necessary for c-Jun-induced anchorage-independent growth in Rat1a cells.
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Academic Article
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Whole genome expression profiling of advance stage papillary serous ovarian cancer reveals activated pathways.
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Academic Article
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Comparison of expression profiles in ovarian epithelium in vivo and ovarian cancer identifies novel candidate genes involved in disease pathogenesis.
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Academic Article
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The anterior gradient homolog 3 (AGR3) gene is associated with differentiation and survival in ovarian cancer.
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Academic Article
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Integrated analysis of multiple microarray datasets identifies a reproducible survival predictor in ovarian cancer.
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Academic Article
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A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer.
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Academic Article
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Identification of DNA copy number changes in microdissected serous ovarian cancer tissue using a cDNA microarray platform.
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Academic Article
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Activator protein-1 contributes to high NaCl-induced increase in tonicity-responsive enhancer/osmotic response element-binding protein transactivating activity.
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Academic Article
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Biomarkers of mucinous tumors of the ovary.
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Academic Article
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Cell cycle and related protein.
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Academic Article
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p21-activated kinase 3 (PAK3) is an AP-1 regulated gene contributing to actin organisation and migration of transformed fibroblasts.
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Academic Article
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Multiomic Analysis of Subtype Evolution and Heterogeneity in High-Grade Serous Ovarian Carcinoma.
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Grant
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The Use of Transcriptional Factors as Targets and Agents in Carcinogenesis
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Grant
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The FGF18/FGFR4 amplicon: Novel therapeutic biomarkers for ovarian cancer
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Grant
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The Molecular Genetics of Gynecologic Cancers
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Grant
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Validation of a genomic signature that predicts for sub-optimal debulking of epithelial ovarian cancer
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Grant
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Novel Biomarkers in Ovarian Cancer
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Grant
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Genomic Stratification of Ovarian Cancer Patients
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Academic Article
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Activation domains of L-Myc and c-Myc determine their transforming potencies in rat embryo cells.
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Academic Article
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Regions within the c-Myc protein that are necessary for transformation are also required for inhibition of differentiation of murine erythroleukemia cells.
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Academic Article
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Structure and expression of the human L-myc gene reveal a complex pattern of alternative mRNA processing.
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Academic Article
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Multiple mechanisms for transcriptional regulation of the myc gene family in small-cell lung cancer.
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Academic Article
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Molecular genetics of lung cancer.
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Academic Article
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Chromosomal deletion, gene amplification, alternative processing, and autocrine growth factor production in the pathogenesis of human lung cancer.
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Academic Article
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Translational research and epithelial carcinogenesis: molecular diagnostic assays now--molecular screening assays soon?
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Academic Article
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Occurrence of p53 gene abnormalities in gastric carcinoma tumors and cell lines.
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Academic Article
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Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73.
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Academic Article
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The role of jun and fos gene family members in 12-O-tetradecanoylphorbol-13-acetate induced hemopoietic differentiation.
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Academic Article
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Expression of the atrial natriuretic factor gene in small cell lung cancer tumors and tumor cell lines.
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Academic Article
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Transcription factors and recessive oncogenes in the pathogenesis of human lung cancer.
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Academic Article
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p53: a frequent target for genetic abnormalities in lung cancer.
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Academic Article
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Deregulated expression of human c-jun transforms primary rat embryo cells in cooperation with an activated c-Ha-ras gene and transforms rat-1a cells as a single gene.
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Academic Article
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Genetic changes in the pathogenesis of lung cancer.
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Academic Article
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A transfected L-myc gene can substitute for c-myc in blocking murine erythroleukemia differentiation.
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Academic Article
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The human L-myc gene encodes multiple nuclear phosphoproteins from alternatively processed mRNAs.
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Academic Article
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Transformation by Raf and other oncogenes renders cells differentially sensitive to growth inhibition by a dominant negative c-jun mutant.
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Academic Article
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Constitutive cJun expression induces partial macrophage differentiation in U-937 cells.
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Academic Article
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Dominant negative mutant of c-Jun inhibits NF-AT transcriptional activity and prevents IL-2 gene transcription.
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Academic Article
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Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells.
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Academic Article
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The molecular biology of lung cancer: application to early detection and prevention.
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Academic Article
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p53 and Ki-ras gene mutations in epithelial ovarian neoplasms.
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Academic Article
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Initiators and promoters of lung cancer.
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Academic Article
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Suppression of oncogene-induced transformation by a deletion mutant of c-jun.
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Academic Article
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Role of c-jun in human myeloid leukemia cell apoptosis induced by pharmacological inhibitors of protein kinase C.
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Academic Article
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Effect of 1-beta-D-arabinofuranosylcytosine on apoptosis and differentiation in human monocytic leukemia cells (U937) expressing a c-Jun dominant-negative mutant protein (TAM67).
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Academic Article
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Breast cancer growth is inhibited by vasoactive intestinal peptide (VIP) hybrid, a synthetic VIP receptor antagonist.
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Academic Article
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PACAP stimulates c-fos mRNAs in small cell lung cancer cells.
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Academic Article
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Regulation of nuclear oncogenes expressed in lung cancer cell lines.
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Academic Article
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Discoveries in the cell cycle and ovarian cancer.
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Academic Article
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Molecular characterization of adenocarcinoma of the cervix.
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Academic Article
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AP1 regulation of proliferation and initiation of apoptosis in erythropoietin-dependent erythroid cells.
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Academic Article
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RRR-alpha-tocopheryl succinate induction of prolonged activation of c-jun amino-terminal kinase and c-jun during induction of apoptosis in human MDA-MB-435 breast cancer cells.
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Academic Article
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cJun overexpression in MCF-7 breast cancer cells produces a tumorigenic, invasive and hormone resistant phenotype.
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Academic Article
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Complementation analysis of measles virus mutants isolated from persistently infected lymphoblastoid cell lines.
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Academic Article
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Abnormal expression of the retinoblastoma gene in ovarian neoplasms and correlation to p53 and K-ras mutations.
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Academic Article
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c-jun and multistage carcinogenesis: association of overexpression of introduced c-jun with progression toward a neoplastic endpoint in mouse JB6 cells sensitive to tumor promoter-induced transformation.
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Academic Article
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The molecular genetics of gyn malignancies.
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Academic Article
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Bombesin stimulates c-fos and c-jun mRNAs in small cell lung cancer cells.
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Academic Article
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Mechanism of action of a dominant-negative mutant of c-Jun.
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Academic Article
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Stable expression of a c-JUN deletion mutant in two malignant mouse epidermal cell lines blocks tumor formation in nude mice.
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Academic Article
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Altered cJUN expression: an early event in human lung carcinogenesis.
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Academic Article
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Regulation of urokinase-type plasminogen activator expression by the v-mos oncogene.
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Academic Article
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Activation and inhibition of the AP-1 complex in human breast cancer cells.
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Academic Article
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The human papillomavirus type 16 E7 gene product interacts with and trans-activates the AP1 family of transcription factors.
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Academic Article
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Dominant-negative mutants of cJun inhibit AP-1 activity through multiple mechanisms and with different potencies.
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Academic Article
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Use of transcription factors as agents and targets for drug development.
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Academic Article
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Analysis of Ki-ras, p53, and MDM2 genes in uterine leiomyomas and leiomyosarcomas.
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Academic Article
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FHIT gene expression in human ovarian, endometrial, and cervical cancer cell lines.
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Academic Article
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Breast cancer cells have lower activating protein 1 transcription factor activity than normal mammary epithelial cells.
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Academic Article
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PACAP hybrid: a new PACAP receptor antagonist.
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Academic Article
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Retinoic acid receptor beta expression and growth inhibition of gynecologic cancer cells by the synthetic retinoid N-(4-hydroxyphenyl) retinamide.
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Academic Article
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PACAP(6-38) inhibits the growth of prostate cancer cells.
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Academic Article
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Tumor necrosis factor alpha gene regulation: enhancement of C/EBPbeta-induced activation by c-Jun.
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Academic Article
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Frequent loss of KAI1 expression in squamous and lymphoid neoplasms. An immunohistochemical study of archival tissues.
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Academic Article
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Activator protein-1 mediates induced but not basal epidermal growth factor receptor gene expression.
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Academic Article
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p27 and cyclin D1 abnormalities in uterine papillary serous carcinoma.
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Academic Article
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Endocervical cancer is associated with an increase in the ligands and receptors for transforming growth factor-beta and a contrasting decrease in p27(Kip1).
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Academic Article
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Lovastatin induces apoptosis in a primitive neuroectodermal tumor cell line in association with RB down-regulation and loss of the G1 checkpoint.
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Academic Article
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c-Jun triggers apoptosis in human vascular endothelial cells.
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Academic Article
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TNF-alpha gene expression in macrophages: regulation by NF-kappa B is independent of c-Jun or C/EBP beta.
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Academic Article
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Ras uses the novel tumor suppressor RASSF1 as an effector to mediate apoptosis.
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Academic Article
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Alterations in the gene expression profile of MCF-7 breast tumor cells in response to c-Jun.
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Academic Article
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In situ detection of unexpected patterns of mutant p53 gene expression in non-small cell lung cancers.
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Academic Article
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RASSF6 is a novel member of the RASSF family of tumor suppressors.
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Academic Article
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Identification of molecular markers and signaling pathway in endometrial cancer in Hong Kong Chinese women by genome-wide gene expression profiling.
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Academic Article
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FOXO3a loss is a frequent early event in high-grade pelvic serous carcinogenesis.
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Academic Article
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Ovarian cancer: genomic analysis.
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Academic Article
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Identification of LMX1B as a novel oncogene in human ovarian cancer.
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Academic Article
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Epithelial ovarian cancer: the molecular genetics of epithelial ovarian cancer.
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Academic Article
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How can molecular abnormalities influence our clinical approach.
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Academic Article
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Inhibition of Kpn?1 mediated nuclear import enhances cisplatin chemosensitivity in cervical cancer.
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Academic Article
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Sex Hormones, Insulin, and Insulin-like Growth Factors in Recurrence of High-Stage Endometrial Cancer.
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Academic Article
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A highly annotated database of genes associated with platinum resistance in cancer.
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Academic Article
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Impact of homologous recombination status and responses with veliparib combined with first-line chemotherapy in ovarian cancer in the Phase 3 VELIA/GOG-3005 study.
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Academic Article
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Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer.
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