 Genes, myc
"Genes, myc" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Family of retrovirus-associated DNA sequences (myc) originally isolated from an avian myelocytomatosis virus. The proto-oncogene myc (c-myc) codes for a nuclear protein which is involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Truncation of the first exon, which appears to regulate c-myc expression, is crucial for tumorigenicity. The human c-myc gene is located at 8q24 on the long arm of chromosome 8.
| Descriptor ID |
D016259
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| MeSH Number(s) |
G05.360.340.024.340.375.500.791.420
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| Concept/Terms |
c-myc Genes- c-myc Genes
- Gene, c-myc
- Genes, c-myc
- c myc Genes
- c-myc Gene
c-myc Proto-Oncogenes- c-myc Proto-Oncogenes
- Proto-Oncogene, c-myc
- Proto-Oncogenes, c-myc
- c myc Proto Oncogenes
- c-myc Proto-Oncogene
v-myc Genes- v-myc Genes
- Gene, v-myc
- Genes, v-myc
- v myc Genes
- v-myc Gene
L-myc Proto-Oncogenes- L-myc Proto-Oncogenes
- L myc Proto Oncogenes
- L-myc Proto-Oncogene
- Proto-Oncogene, L-myc
- Proto-Oncogenes, L-myc
myc Oncogene- myc Oncogene
- Oncogene, myc
- Oncogenes, myc
- myc Oncogenes
N-myc Genes- N-myc Genes
- Gene, N-myc
- Genes, N-myc
- N myc Genes
- N-myc Gene
N-myc Proto-Oncogenes- N-myc Proto-Oncogenes
- N myc Proto Oncogenes
- N-myc Proto-Oncogene
- Proto-Oncogene, N-myc
- Proto-Oncogenes, N-myc
v-myc Oncogenes- v-myc Oncogenes
- Oncogene, v-myc
- Oncogenes, v-myc
- v myc Oncogenes
- v-myc Oncogene
L-myc Genes- L-myc Genes
- Gene, L-myc
- Genes, L-myc
- L myc Genes
- L-myc Gene
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Below are MeSH descriptors whose meaning is more general than "Genes, myc".
Below are MeSH descriptors whose meaning is more specific than "Genes, myc".
This graph shows the total number of publications written about "Genes, myc" by people in UAMS Profiles by year, and whether "Genes, myc" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2021 | 0 | 1 | 1 | | 2020 | 2 | 1 | 3 | | 2019 | 1 | 1 | 2 | | 2018 | 1 | 0 | 1 | | 2015 | 2 | 0 | 2 | | 2014 | 0 | 1 | 1 | | 2013 | 3 | 0 | 3 | | 2012 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 1997 | 1 | 0 | 1 | | 1996 | 0 | 1 | 1 | | 1994 | 1 | 0 | 1 | | 1992 | 2 | 0 | 2 |
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Below are the most recent publications written about "Genes, myc" by people in Profiles over the past ten years.
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Ketkar A, Smith L, Johnson C, Richey A, Berry M, Hartman JH, Maddukuri L, Reed MR, Gunderson JEC, Leung JWC, Eoff RL. Human Rev1 relies on insert-2 to promote selective binding and accurate replication of stabilized G-quadruplex motifs. Nucleic Acids Res. 2021 02 26; 49(4):2065-2084.
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Shponka V, Reveles CY, Alam S, Jaramillo M, Maguire A, Rimsza LM, Kendrick S. Frequent expression of activation-induced cytidine deaminase in diffuse large B-cell lymphoma tissues from persons living with HIV. AIDS. 2020 11 15; 34(14):2025-2035.
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Ramos JC, Sparano JA, Chadburn A, Reid EG, Ambinder RF, Siegel ER, Moore PC, Rubinstein PG, Durand CM, Cesarman E, Aboulafia D, Baiocchi R, Ratner L, Kaplan L, Capoferri AA, Lee JY, Mitsuyasu R, Noy A. Impact of Myc in HIV-associated non-Hodgkin lymphomas treated with EPOCH and outcomes with vorinostat (AMC-075 trial). Blood. 2020 09 10; 136(11):1284-1297.
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Pina-Oviedo S, Bellamy WT, Gokden M. Analysis of primary central nervous system large B-cell lymphoma in the era of high-grade B-cell lymphoma: Detection of two cases with MYC and BCL6 rearrangements in a cohort of 12 cases. Ann Diagn Pathol. 2020 Oct; 48:151610.
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Sun F, Cheng Y, Walsh SA, Acevedo MR, Jing X, Han SS, Pisano MD, Tomasson MH, Lichtenstein AK, Zhan F, Hari P, Janz S. Osteolytic disease in IL-6 and Myc dependent mouse model of human myeloma. Haematologica. 2020 03; 105(3):e111-e115.
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Mikulasova A, Ashby C, Tytarenko RG, Qu P, Rosenthal A, Dent JA, Ryan KR, Bauer MA, Wardell CP, Hoering A, Mavrommatis K, Trotter M, Deshpande S, Yaccoby S, Tian E, Keats J, Auclair D, Jackson GH, Davies FE, Thakurta A, Morgan GJ, Walker BA. Microhomology-mediated end joining drives complex rearrangements and overexpression of MYC and PVT1 in multiple myeloma. Haematologica. 2020 04; 105(4):1055-1066.
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Walker BA. Whole Exome Sequencing in Multiple Myeloma to Identify Somatic Single Nucleotide Variants and Key Translocations Involving Immunoglobulin Loci and MYC. Methods Mol Biol. 2018; 1792:71-95.
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Caponetti GC, Dave BJ, Perry AM, Smith LM, Jain S, Meyer PN, Bast M, Bierman PJ, Bociek RG, Vose JM, Armitage JO, Aoun P, Fu K, Greiner TC, Chan WC, Sanger WG, Weisenburger DD. Isolated MYC cytogenetic abnormalities in diffuse large B-cell lymphoma do not predict an adverse clinical outcome. Leuk Lymphoma. 2015; 56(11):3082-9.
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Xiang Z, Abdallah AO, Govindarajan R, Mehta P, Emanuel PD, Papenhausen P, Schichman SA. MYC amplification in multiple marker chromosomes and EZH2 microdeletion in a man with acute myeloid leukemia. Cancer Genet. 2015 Mar; 208(3):96-100.
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