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Search Results to Fenghuang Zhan

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Zhan, Fenghuang

One or more keywords matched the following items that are connected to Zhan, Fenghuang

Item Type	Name
Academic Article	Toward the identification of distinct molecular and clinical entities of multiple myeloma using global gene expression profiling.
Academic Article	The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma.
Academic Article	Gene expression profiling and multiple myeloma.
Academic Article	Gene expression profiles of primary HPV16- and HPV18-infected early stage cervical cancers and normal cervical epithelium: identification of novel candidate molecular markers for cervical cancer diagnosis and therapy.
Academic Article	Gene-expression signature of benign monoclonal gammopathy evident in multiple myeloma is linked to good prognosis.
Academic Article	Gene expression profiles in primary ovarian serous papillary tumors and normal ovarian epithelium: identification of candidate molecular markers for ovarian cancer diagnosis and therapy.
Academic Article	Continuous absence of metaphase-defined cytogenetic abnormalities, especially of chromosome 13 and hypodiploidy, ensures long-term survival in multiple myeloma treated with Total Therapy I: interpretation in the context of global gene expression.
Academic Article	The distinct gene expression profiles of chronic lymphocytic leukemia and multiple myeloma suggest different anti-apoptotic mechanisms but predict only some differences in phenotype.
Academic Article	High heparanase activity in multiple myeloma is associated with elevated microvessel density.
Academic Article	RHAMM expression and isoform balance predict aggressive disease and poor survival in multiple myeloma.
Academic Article	Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma.
Academic Article	CKS1B, overexpressed in aggressive disease, regulates multiple myeloma growth and survival through SKP2- and p27Kip1-dependent and -independent mechanisms.
Academic Article	Heparanase enhances syndecan-1 shedding: a novel mechanism for stimulation of tumor growth and metastasis.
Academic Article	Dickkopf-1 (DKK1) is a widely expressed and potent tumor-associated antigen in multiple myeloma.
Academic Article	Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma.
Academic Article	Fibroblast activation protein (FAP) is upregulated in myelomatous bone and supports myeloma cell survival.
Academic Article	Gene expression profiles of tumor biology provide a novel approach to prognosis and may guide the selection of therapeutic targets in multiple myeloma.
Academic Article	Gene expression profiling defines a high-risk entity of multiple myeloma.
Academic Article	The molecular classification of multiple myeloma.
Academic Article	Over-expression of CKS1B activates both MEK/ERK and JAK/STAT3 signaling pathways and promotes myeloma cell drug-resistance.
Academic Article	ARK5 is transcriptionally regulated by the Large-MAF family and mediates IGF-1-induced cell invasion in multiple myeloma: ARK5 as a new molecular determinant of malignant multiple myeloma.
Academic Article	Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transplantation.
Academic Article	Tumor cell gene expression changes following short-term in vivo exposure to single agent chemotherapeutics are related to survival in multiple myeloma.
Academic Article	NEK2 induces drug resistance mainly through activation of efflux drug pumps and is associated with poor prognosis in myeloma and other cancers.
Academic Article	High-risk myeloma: a gene expression based risk-stratification model for newly diagnosed multiple myeloma treated with high-dose therapy is predictive of outcome in relapsed disease treated with single-agent bortezomib or high-dose dexamethasone.
Academic Article	CS1, a potential new therapeutic antibody target for the treatment of multiple myeloma.
Academic Article	High expression of BCL3 in human myeloma cells is associated with increased proliferation and inferior prognosis.
Academic Article	NY-ESO-1 is highly expressed in poor-prognosis multiple myeloma and induces spontaneous humoral and cellular immune responses.
Academic Article	A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1.
Academic Article	The oxidative stress response regulates DKK1 expression through the JNK signaling cascade in multiple myeloma plasma cells.
Academic Article	Overexpression and involvement in migration by the metastasis-associated phosphatase PRL-3 in human myeloma cells.
Academic Article	Benefit of complete response in multiple myeloma limited to high-risk subgroup identified by gene expression profiling.
Academic Article	Identification of early growth response protein 1 (EGR-1) as a novel target for JUN-induced apoptosis in multiple myeloma.
Academic Article	RARalpha2 expression is associated with disease progression and plays a crucial role in efficacy of ATRA treatment in myeloma.
Academic Article	Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells.
Academic Article	An analysis of the clinical and biologic significance of TP53 loss and the identification of potential novel transcriptional targets of TP53 in multiple myeloma.
Academic Article	High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients.
Academic Article	Combinatorial efficacy of anti-CS1 monoclonal antibody elotuzumab (HuLuc63) and bortezomib against multiple myeloma.
Concept	Alleles
Concept	Multigene Family
Concept	Base Sequence
Concept	Gene Expression Regulation, Leukemic
Concept	Genes, abl
Concept	Molecular Sequence Data
Concept	Genes, myc
Concept	Genes, Tumor Suppressor
Concept	Gene Expression
Concept	Gene Expression Regulation, Enzymologic
Concept	Transcriptome
Concept	Gene Knockout Techniques
Concept	Gene Expression Regulation, Developmental
Concept	Gene Expression Regulation
Concept	Gene Silencing
Concept	Genome, Human
Concept	Gene Dosage
Concept	Gene Deletion
Concept	Gene Expression Profiling
Concept	Gene Knockdown Techniques
Concept	Genes, Neoplasm
Concept	Gene Expression Regulation, Neoplastic
Academic Article	Gene expression profiling reveals different pathways related to Abl and other genes that cooperate with c-Myc in a model of plasma cell neoplasia.
Academic Article	Gene expression profiling of plasma cells and plasmablasts: toward a better understanding of the late stages of B-cell differentiation.
Academic Article	Expression of PAX5 in CD20-positive multiple myeloma assessed by immunohistochemistry and oligonucleotide microarray.
Academic Article	Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib.
Academic Article	Smoldering multiple myeloma.
Academic Article	Heterologous tissue culture expression signature predicts human breast cancer prognosis.
Academic Article	Generation of polyclonal plasmablasts from peripheral blood B cells: a normal counterpart of malignant plasmablasts.
Academic Article	Myeloma cell-derived Runx2 promotes myeloma progression in bone.
Academic Article	Destabilizing NEK2 overcomes resistance to proteasome inhibition in multiple myeloma.
Grant	Gene expression profiling vs MRD assessment in Myeloma
Academic Article	Gene Expression Profiling Reveals Aberrant T-cell Marker Expression on Tumor Cells of Waldenstr?m's Macroglobulinemia.
Academic Article	Decreased ferroportin promotes myeloma cell growth and osteoclast differentiation.
Academic Article	Junctional adhesion molecule-A is overexpressed in advanced multiple myeloma and determines response to oncolytic reovirus.
Academic Article	RARa2 expression confers myeloma stem cell features.
Academic Article	Upregulation of FOXM1 leads to diminished drug sensitivity in myeloma.
Academic Article	Upregulation of FOXM1 in a subset of relapsed myeloma results in poor outcome.
Academic Article	NEDD8 Inhibition Overcomes CKS1B-Induced Drug Resistance by Upregulation of p21 in Multiple Myeloma.
Academic Article	Neoplastic plasma cell aberrant antigen expression patterns and their association with genetic abnormalities.
Academic Article	Ferroportin downregulation promotes cell proliferation by modulating the Nrf2-miR-17-5p axis in multiple myeloma.
Academic Article	Serum high expression of miR-214 and miR-135b as novel predictor for myeloma bone disease development and prognosis.
Academic Article	TRIP13 impairs mitotic checkpoint surveillance and is associated with poor prognosis in multiple myeloma.
Academic Article	Osteolytic disease in IL-6 and Myc dependent mouse model of human myeloma.
Academic Article	Profiling bortezomib resistance identifies secondary therapies in a mouse myeloma model.
Academic Article	Scavenger receptor class A member 3 (SCARA3) in disease progression and therapy resistance in multiple myeloma.
Academic Article	Down-regulation of 11?-hydroxysteroid dehydrogenase type 2 by bortezomib sensitizes Jurkat leukemia T cells against glucocorticoid-induced apoptosis.
Academic Article	Chromosome 1q21 gains confer inferior outcomes in multiple myeloma treated with bortezomib but copy number variation and percentage of plasma cells involved have no additional prognostic value.
Academic Article	Myeloma cells resistance to NK cell lysis mainly involves an HLA class I-dependent mechanism.
Academic Article	Mitochondrial-Targeted Decyl-Triphenylphosphonium Enhances 2-Deoxy-D-Glucose Mediated Oxidative Stress and Clonogenic Killing of Multiple Myeloma Cells.
Academic Article	Low serum miR-19a expression as a novel poor prognostic indicator in multiple myeloma.
Academic Article	Copper-zinc superoxide dismutase-mediated redox regulation of bortezomib resistance in multiple myeloma.
Academic Article	Polycomb-like Protein 3 Induces Proliferation and Drug Resistance in Multiple Myeloma and Is Regulated by miRNA-15a.
Grant	Retinoid Based Treatment Approaches to Target the Myeloma Stem Cell
Grant	NEK2 Over-expression Causes Drug Resistance in Myeloma
Academic Article	RFWD2 induces cellular proliferation and selective proteasome inhibitor resistance by mediating P27 ubiquitination in multiple myeloma.
Academic Article	The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma.
Grant	Biological Validation of Candidate Myeloma Driver Genes
Academic Article	Therapeutic effects of oligo-single-stranded DNA mimicking of hsa-miR-15a-5p on multiple myeloma.
Academic Article	Role of NEK2A in human cancer and its therapeutic potentials.
Academic Article	Epigenetic Deregulation of Telomere-Related Genes in Newly Diagnosed Multiple Myeloma Patients.
Academic Article	WDR26 and MTF2 are therapeutic targets in multiple myeloma.
Academic Article	FOXM1 regulates glycolysis and energy production in multiple myeloma.
Academic Article	A gene signature can predict risk of MGUS progressing to multiple myeloma.

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